Alexander Simon

Summary

Affiliation: University of Arizona
Country: USA

Publications

  1. request reprint
    Simon A, Chen H, Jackson C. Cx37 and Cx43 localize to zona pellucida in mouse ovarian follicles. Cell Commun Adhes. 2006;13:61-77 pubmed
    ..We suggest that in addition to its role in oocyte-granulosa cell communication, Cx37 could enable a distinct communication pathway between those granulosa cells that are in direct contact with the oocyte. ..
  2. request reprint
    Simon A, McWhorter A. Decreased intercellular dye-transfer and downregulation of non-ablated connexins in aortic endothelium deficient in connexin37 or connexin40. J Cell Sci. 2003;116:2223-36 pubmed
    ..Furthermore, Cx37 and Cx40 are codependent on each other for optimal expression in vascular endothelium. ..
  3. request reprint
    Simon A, McWhorter A, Dones J, Jackson C, Chen H. Heart and head defects in mice lacking pairs of connexins. Dev Biol. 2004;265:369-83 pubmed
    ..Moreover, ablating different pairs of cardiac connexins results in distinct heart defects, suggesting both common and unique functions for Cx40, Cx43, and Cx37 during cardiac morphogenesis. ..
  4. request reprint
    Simon A, McWhorter A, Chen H, Jackson C, Ouellette Y. Decreased intercellular communication and connexin expression in mouse aortic endothelium during lipopolysaccharide-induced inflammation. J Vasc Res. 2004;41:323-33 pubmed
    ..These results suggest that LPS mediates changes in endothelial gap junction-mediated communication, at least in part, through modulation of Cx40 and Cx37 levels. ..

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Detail Information

Publications4

  1. request reprint
    Simon A, Chen H, Jackson C. Cx37 and Cx43 localize to zona pellucida in mouse ovarian follicles. Cell Commun Adhes. 2006;13:61-77 pubmed
    ..We suggest that in addition to its role in oocyte-granulosa cell communication, Cx37 could enable a distinct communication pathway between those granulosa cells that are in direct contact with the oocyte. ..
  2. request reprint
    Simon A, McWhorter A. Decreased intercellular dye-transfer and downregulation of non-ablated connexins in aortic endothelium deficient in connexin37 or connexin40. J Cell Sci. 2003;116:2223-36 pubmed
    ..Furthermore, Cx37 and Cx40 are codependent on each other for optimal expression in vascular endothelium. ..
  3. request reprint
    Simon A, McWhorter A, Dones J, Jackson C, Chen H. Heart and head defects in mice lacking pairs of connexins. Dev Biol. 2004;265:369-83 pubmed
    ..Moreover, ablating different pairs of cardiac connexins results in distinct heart defects, suggesting both common and unique functions for Cx40, Cx43, and Cx37 during cardiac morphogenesis. ..
  4. request reprint
    Simon A, McWhorter A, Chen H, Jackson C, Ouellette Y. Decreased intercellular communication and connexin expression in mouse aortic endothelium during lipopolysaccharide-induced inflammation. J Vasc Res. 2004;41:323-33 pubmed
    ..These results suggest that LPS mediates changes in endothelial gap junction-mediated communication, at least in part, through modulation of Cx40 and Cx37 levels. ..