Research Topics
| Eric A F SimoesSummaryAffiliation: University of Colorado Health Sciences Center Country: USA Publications
| Collaborators
|
Detail Information
Publications
Environmental and demographic risk factors for respiratory syncytial virus lower respiratory tract diseaseEric A F Simoes
Section of Infectious Diseases, The University of Colorado School of Medicine and The Children s Hospital, Denver, Colorado 80218, USA
J Pediatr 143:S118-26. 2003..To critically review the literature examining risk factors for development of severe respiratory syncytial virus lower respiratory tract infection (RSV LRI)...
Optimization and clinical validation of a pathogen detection microarrayChristopher W Wong
Genomic Technologies, Genome Institute of Singapore, Republic of Singapore
Genome Biol 8:R93. 2007..Our findings show that microarrays can be used for the robust and accurate diagnosis of pathogens, and further substantiate the use of microarray technology in clinical diagnostics...
Clinical case review: a method to improve identification of true clinical and radiographic pneumonia in children meeting the World Health Organization definition for pneumoniaTaneli Puumalainen
National Public Health Institute, Mannerheimintie 166, FIN 00300 Helsinki, Finland
BMC Infect Dis 8:95. 2008..The definition is also commonly used as an entry criteria or endpoint in different intervention and disease burden studies...
A predictive model for respiratory syncytial virus (RSV) hospitalisation of premature infants born at 33-35 weeks of gestational age, based on data from the Spanish FLIP StudyEric A F Simoes
Department of Pediatrics, The University of Colorado School of Medicine and The Children s Hospital, Denver, USA
Respir Res 9:78. 2008..The aim of this study, conducted in Europe, was to develop a validated risk factor based model to predict RSV-related hospitalisation in premature infants born 33-35 weeks' gestational age (GA)...
Maternal smoking, asthma, and bronchiolitis: clear-cut association or equivocal evidence?Eric A F Simoes
Department of Pediatrics, University of Colorado at Denver and Health Sciences Center and Children s Hospital, 1056 E 19th Ave, B070, Denver, CO 80218, USA
Pediatrics 119:1210-2. 2007
Management of severely ill children at first-level health facilities in sub-Saharan Africa when referral is difficultEric A F Simoes
University of Colorado School of Medicine and The Children s Hospital, Denver, USA
Bull World Health Organ 81:522-31. 2003....
Immunoprophylaxis of respiratory syncytial virus: global experienceEric A F Simoes
Department of Pediatrics, Section of Infectious Diseases, The University of Colorado School of Medicine and The Children s Hospital, Denver, Colorado, USA
Respir Res 3:S26-33. 2002..The efficacy and safety of palivizumab continue to be supported by both clinical trial and outcomes data...
Palivizumab prophylaxis, respiratory syncytial virus, and subsequent recurrent wheezingEric A F Simoes
Department of Pediatric Infectious Diseases, University of Colorado School of Medicine and The Children s Hospital, Denver, CO 80218, USA
J Pediatr 151:34-42, 42.e1. 2007..We hypothesized that palivizumab, by ameliorating or preventing early RSV LRTI in preterm infants, might decrease later recurrent wheezing...
The effect of respiratory syncytial virus on subsequent recurrent wheezing in atopic and nonatopic childrenEric A F Simoes
Department of Pediatric Infectious Diseases, University of Colorado School of Medicine, and The Children s Hospital, Aurora, Colo, USA
J Allergy Clin Immunol 126:256-62. 2010..Although respiratory syncytial virus (RSV) lower respiratory tract infections (LRTIs) in early life are followed by later airway hyperreactivity, it is unclear whether there is a causal relationship between this and an atopic diathesis...
Down syndrome and hospitalizations due to respiratory syncytial virus: a population-based studyPhilip Zachariah
Department of Pediatrics, University of Colorado, Denver, CO, USA
J Pediatr 160:827-31.e1. 2012..To assess the risk estimates for respiratory syncytial virus (RSV) hospitalization in children with Down syndrome (DS) and the clinical features and severity of RSV lower respiratory tract infection (LRTI) in hospitalized children...
European risk factors' model to predict hospitalization of premature infants born 33-35 weeks' gestational age with respiratory syncytial virus: validation with Italian dataEric A F Simoes
Department of Pediatrics, Section of Infectious Diseases, The University of Colorado Denver School of Medicine and The Children s Hospital, Denver, Colorado, USA
J Matern Fetal Neonatal Med 24:152-7. 2011..The model correctly classified 71% of cases and the area under the receiver operating characteristic (ROC) curve was 0.791. To assess its applicability in Italy, the model was validated against data from the Osservatorio VRS study...
The epidemiology of respiratory syncytial virus lower respiratory tract infections in children less than 5 years of age in IndonesiaEric A F Simoes
Section of Infectious Diseases, Department of Pediatrics, University of Colorado at Denver Health Sciences Center and The Children s Hospital, Denver, CO, USA
Pediatr Infect Dis J 30:778-84. 2011..Although the epidemiology of respiratory syncytial virus (RSV) lower respiratory tract infections (LRI) is well known in industrialized countries, the burden in developing Asian countries is not well studied...
Predictors of the duration of the respiratory syncytial virus seasonPhilip Zachariah
Department of Pediatrics, Section of Infectious Diseases, University of Colorado Denver, Anschutz Medical Campus, Denver, CO, USA
Pediatr Infect Dis J 28:772-6. 2009..To enable accurate recommendations for surveillance and prophylaxis at a local level, we examined this variation in detail and determined predictors for the duration of the RSV season...
RSV disease in the pediatric population: epidemiology, seasonal variability, and long-term outcomesEric A F Simoes
Division of Infectious Diseases, University of Colorado Denver Health Sciences Center, Denver, USA
Manag Care 17:3-6, discussion 18-9. 2008..Although hospitalization is a major outcome of severe RSV infections in infants, the development of wheezing and physician-diagnosed asthma later in life may be a long-term outcome that should be considered...
Cell-to-cell spread of poliovirus in the spinal cord of bonnet monkeys (Macaca radiata)E M Ponnuraj
Department of Microbiology and Virology, Christian Medical College and Hospital, Vellore, India
J Gen Virol 79:2393-403. 1998..onwards. The temporal distribution of the virus spread, distribution of viral RNA, histopathological and clinical changes indicate a cell-to-cell spread of poliovirus in the CNS, having gained access to the CNS from the peripheral nerve...
Sabin attenuated LSc/2ab strain of poliovirus spreads to the spinal cord from a peripheral nerve in bonnet monkeys (Macaca radiata)E M Ponnuraj
Department of Microbiology and Virology, Christian Medical College Hospital, 632004, Vellore, India
J Gen Virol 82:1329-38. 2001..Spread of attenuated poliovirus in spinal cord neurons without causing paralysis following inoculation into the ulnar nerve is an important finding...
Increased replication of respiratory syncytial virus (RSV) in pulmonary infiltrates is associated with enhanced histopathological disease in bonnet monkeys (Macaca radiata) pre-immunized with a formalin-inactivated RSV vaccineE M Ponnuraj
Department of Pediatrics, Box B140, Section of Infectious Diseases, University of Colorado Health Sciences Center, 4200 East 9th Avenue, Denver, CO 80262, USA
J Gen Virol 82:2663-74. 2001....
Hospitalizations due to respiratory syncytial virus in children with congenital malformationsPhilip Zachariah
Section of Infectious Diseases, Department of Pediatrics, University of Colorado Denver, and The Children s Hospital, Denver, CO, USA
Pediatr Infect Dis J 30:442-5. 2011....
Effect of altitude on hospitalizations for respiratory syncytial virus infectionJulie A Choudhuri
Preventive Medicine and Biometrics, University of Colorado and Health Sciences Center, Denver, Colorado, USA
Pediatrics 117:349-56. 2006..Practitioners in these regions should consider additional efforts to educate parents about RSV infection and its prevention and the importance of early treatment...
Antibodies for prevention and treatment of respiratory syncytial virus infections in childrenBessey Geevarghese
Department of Pediatrics, Section of Infectious Diseases, University of Colorado, Denver, CO, USA
Antivir Ther 17:201-11. 2012..This review will concentrate on the past, present and future history of RSV immunoprophylaxis with an emphasis on the role of polyclonal and monoclonal antibodies...
Respiratory syncytial virus vaccine: a systematic overview with emphasis on respiratory syncytial virus subunit vaccinesE A Simoes
Department of Pediatrics, Section of Infectious Diseases, Health Sciences Center, University of Colorado, Denver, CO, USA
Vaccine 20:954-60. 2001..However, RSV subunit vaccines must be tested in large field trials because of concerns about the appropriateness of pooling, the risk of publication bias and the fact that the clinically important outcome of RSV LRI was not reduced...
Antibody-dependent enhancement, a possible mechanism in augmented pulmonary disease of respiratory syncytial virus in the Bonnet monkey modelEsther M Ponnuraj
Department of Pediatrics, University of Colorado Health Sciences Center, Denver, Colorado, USA
J Infect Dis 187:1257-63. 2003..In the presence of serum samples from animals immunized with FI-RSV, an increased number of U937 cells was infected. The enhancement index correlated positively with the pathologic scores of the FI-RSV-vaccinated monkeys...
WU and KI polyomavirus infections in pediatric hematology/oncology patients with acute respiratory tract illnessSuchitra Rao
Department of Pediatrics, B158 The Children s Hospital and University of Colorado School of Medicine, Aurora, CO 80045, USA
J Clin Virol 52:28-32. 2011..Other polyomaviruses (BKPyV and JCPyV) have been associated with illness in immunocompromised patients, and some studies suggest a higher prevalence of WUPyV and KIPyV in this population...
Safety and pharmacokinetics of an intramuscular monoclonal antibody (SB 209763) against respiratory syncytial virus (RSV) in infants and young children at risk for severe RSV diseaseH C Meissner
Department of Pediatrics, New England Medical Center, Tufts University School of Medicine, Boston, Massachusetts 02111, USA
Antimicrob Agents Chemother 43:1183-8. 1999....
