Michael J Simmons

Summary

Affiliation: University of Minnesota
Country: USA

Publications

  1. doi request reprint Maternal enhancement of cytotype regulation in Drosophila melanogaster by genetic interactions between telomeric P elements and non-telomeric transgenic P elements
    Michael J Simmons
    Department of Genetics, Cell Biology and Development, University of Minnesota, St Paul, MN 55108 1095, USA
    Genet Res (Camb) 94:339-51. 2012
  2. pmc Cytotype regulation by telomeric P elements in Drosophila melanogaster: evidence for involvement of an RNA interference gene
    Michael J Simmons
    Department of Genetics, Cell Biology, and Development, 250 BioScience Center, University of Minnesota, 1445 Gortner Avenue, St Paul, MN 55108 1095, USA
    Genetics 176:1945-55. 2007
  3. pmc Cytotype regulation by telomeric P elements in Drosophila melanogaster: interactions with P elements from M' strains
    Michael J Simmons
    Department of Genetics, Cell Biology, and Development, 250 BioScience Center, University of Minnesota, 1445 Gortner Avenue, St Paul, MN 55108 1095, USA
    Genetics 176:1957-66. 2007
  4. doi request reprint Maternal impairment of transposon regulation in Drosophila melanogaster by mutations in the genes aubergine, piwi and Suppressor of variegation 205
    Michael J Simmons
    Department of Genetics, Cell Biology and Development, University of Minnesota, St Paul, MN 55108 1095, USA
    Genet Res (Camb) 92:261-72. 2010
  5. pmc The P cytotype in Drosophila melanogaster: a maternally transmitted regulatory state of the germ line associated with telomeric P elements
    Michael J Simmons
    Department of Genetics, Cell Biology and Development, University of Minnesota, Saint Paul, Minnesota 55108 1095, USA
    Genetics 166:243-54. 2004
  6. pmc Establishment and maintenance of the P cytotype associated with telomeric P elements in Drosophila melanogaster
    Jarad B Niemi
    Department of Genetics, Cell Biology and Development, University of Minnesota, Saint Paul, Minnesota 55108 1095, USA
    Genetics 166:255-64. 2004
  7. doi request reprint Cytotype regulation by telomeric P elements in Drosophila melanogaster: variation in regulatory strength and maternal effects
    Michael W Thorp
    Department of Genetics, Cell Biology and Development, University of Minnesota, St Paul, MN 55108 1095, USA
    Genet Res (Camb) 91:327-36. 2009
  8. pmc Regulation of P-element transposase activity in Drosophila melanogaster by hobo transgenes that contain KP elements
    Michael J Simmons
    Department of Genetics, Cell Biology and Development, University of Minnesota, Saint Paul, Minnesota 55108 1095, USA
    Genetics 161:205-15. 2002
  9. pmc Impairment of cytotype regulation of P-element activity in Drosophila melanogaster by mutations in the Su(var)205 gene
    Kevin J Haley
    Department of Genetics, Cell Biology and Development, University of Minnesota, St Paul, 55108, USA
    Genetics 171:583-95. 2005
  10. pmc Cytotype regulation of P transposable elements in Drosophila melanogaster: repressor polypeptides or piRNAs?
    Philip A Jensen
    Department of Genetics, Cell Biology, and Development, University of Minnesota, St Paul, Minnesota 55108 1095, USA
    Genetics 179:1785-93. 2008

Collaborators

  • Jeremy R Stuart
  • Jarad B Niemi
  • Kevin J Haley
  • Michael W Thorp
  • Eric W Cross
  • Philip A Jensen
  • Jamie Paterson
  • John D Raymond
  • Eric J Chapman
  • Joseph W Goodman
  • Michael P Goodpaster
  • Kevin O'Hare
  • Ryan Patrek
  • Douglas Swedzinski
  • Peter J Merriman
  • Paul E Kocian
  • Samuel Lockner

Detail Information

Publications15

  1. doi request reprint Maternal enhancement of cytotype regulation in Drosophila melanogaster by genetic interactions between telomeric P elements and non-telomeric transgenic P elements
    Michael J Simmons
    Department of Genetics, Cell Biology and Development, University of Minnesota, St Paul, MN 55108 1095, USA
    Genet Res (Camb) 94:339-51. 2012
    ....
  2. pmc Cytotype regulation by telomeric P elements in Drosophila melanogaster: evidence for involvement of an RNA interference gene
    Michael J Simmons
    Department of Genetics, Cell Biology, and Development, 250 BioScience Center, University of Minnesota, 1445 Gortner Avenue, St Paul, MN 55108 1095, USA
    Genetics 176:1945-55. 2007
    ..Cytotype regulation by telomeric P elements may be tied to a system that uses RNAi to regulate the activities of telomeric retrotransposons in Drosophila...
  3. pmc Cytotype regulation by telomeric P elements in Drosophila melanogaster: interactions with P elements from M' strains
    Michael J Simmons
    Department of Genetics, Cell Biology, and Development, 250 BioScience Center, University of Minnesota, 1445 Gortner Avenue, St Paul, MN 55108 1095, USA
    Genetics 176:1957-66. 2007
    ..This synergism between TP and M' P elements also appears to persist for at least one generation after the TP has been removed from the genotype...
  4. doi request reprint Maternal impairment of transposon regulation in Drosophila melanogaster by mutations in the genes aubergine, piwi and Suppressor of variegation 205
    Michael J Simmons
    Department of Genetics, Cell Biology and Development, University of Minnesota, St Paul, MN 55108 1095, USA
    Genet Res (Camb) 92:261-72. 2010
    ..These findings are discussed in terms of a model of P-element regulation that involves post-transcriptional and chromatin re-organizing events mediated by maternally transmitted small RNAs derived from the telomeric P element...
  5. pmc The P cytotype in Drosophila melanogaster: a maternally transmitted regulatory state of the germ line associated with telomeric P elements
    Michael J Simmons
    Department of Genetics, Cell Biology and Development, University of Minnesota, Saint Paul, Minnesota 55108 1095, USA
    Genetics 166:243-54. 2004
    ..Regulation by telomeric P elements appears to be epistatic to regulation by repressor P polypeptides...
  6. pmc Establishment and maintenance of the P cytotype associated with telomeric P elements in Drosophila melanogaster
    Jarad B Niemi
    Department of Genetics, Cell Biology and Development, University of Minnesota, Saint Paul, Minnesota 55108 1095, USA
    Genetics 166:255-64. 2004
    ..However, some of the stocks do not attain the regulatory ability of the original population...
  7. doi request reprint Cytotype regulation by telomeric P elements in Drosophila melanogaster: variation in regulatory strength and maternal effects
    Michael W Thorp
    Department of Genetics, Cell Biology and Development, University of Minnesota, St Paul, MN 55108 1095, USA
    Genet Res (Camb) 91:327-36. 2009
    ....
  8. pmc Regulation of P-element transposase activity in Drosophila melanogaster by hobo transgenes that contain KP elements
    Michael J Simmons
    Department of Genetics, Cell Biology and Development, University of Minnesota, Saint Paul, Minnesota 55108 1095, USA
    Genetics 161:205-15. 2002
    ....
  9. pmc Impairment of cytotype regulation of P-element activity in Drosophila melanogaster by mutations in the Su(var)205 gene
    Kevin J Haley
    Department of Genetics, Cell Biology and Development, University of Minnesota, St Paul, 55108, USA
    Genetics 171:583-95. 2005
    ..The regulatory abilities of the TP5 and TP6 elements are therefore not equally susceptible to the effects of elongated telomeres in the mutant Su(var)205 and Gaiano stocks...
  10. pmc Cytotype regulation of P transposable elements in Drosophila melanogaster: repressor polypeptides or piRNAs?
    Philip A Jensen
    Department of Genetics, Cell Biology, and Development, University of Minnesota, St Paul, Minnesota 55108 1095, USA
    Genetics 179:1785-93. 2008
    ....
  11. pmc Telomeric P elements associated with cytotype regulation of the P transposon family in Drosophila melanogaster
    Jeremy R Stuart
    Department of Genetics, Cell Biology and Development, University of Minnesota, Twin Cities, St Paul, Minnesota 55108, USA
    Genetics 162:1641-54. 2002
    ..Collectively, these findings indicate that the regulatory abilities of telomeric P elements are similar to those of the P cytotype...
  12. pmc Maternal transmission of P element transposase activity in Drosophila melanogaster depends on the last P intron
    Michael J Simmons
    Department of Genetics, Cell Biology, and Development, University of Minnesota, Twin Cities 250 BioScience Center, 1445 Gortner Avenue, St Paul, MN 55108 1095, USA
    Proc Natl Acad Sci U S A 99:9306-9. 2002
    ..This same intron limits expression of the P transposase to the germ line of Drosophila. Thus, the last P intron has two important biological functions...
  13. doi request reprint Does RNA interference influence meiotic crossing over in Drosophila melanogaster?
    Eric W Cross
    Department of Genetics, Cell Biology and Development, University of Minnesota, St Paul, MN 55108 1095, USA
    Genet Res (Camb) 90:253-8. 2008
    ..Mutations in aub and piwi did not affect the frequency of crossing over in the centric heterochromatin of chromosome II; nor did a balancer chromosome III...
  14. pmc A hobo transgene that encodes the P-element transposase in Drosophila melanogaster: autoregulation and cytotype control of transposase activity
    Michael J Simmons
    Department of Genetics, Cell Biology and Development, University of Minnesota, Saint Paul, Minnesota 55108 1095, USA
    Genetics 161:195-204. 2002
    ..However, this ability and the ability to induce P-element excisions are repressed by the P cytotype, a chromosomal/cytoplasmic state that regulates P elements in the germline...
  15. ncbi request reprint Transcription of the singed-weak mutation of Drosophila melanogaster: elimination of P-element sequences by RNA splicing and repression of singed transcription in a P genetic background
    Jamie Paterson
    Division of Cell and Molecular Biology, Faculty of Natural Sciences, Imperial College London, Biochemistry Building, South Kensington Campus, London, SW7 2AZ, UK
    Mol Genet Genomics 278:53-64. 2007
    ....