Affiliation: University of Texas Medical Branch
- Herpesvirus and multiple sclerosisA Simmons
Department of Pediatrics, Sealy Center for Vaccine Development, University of Texas Medical Branch, 301 University Boulevard, Galveston, TX 77555 0739, USA
Herpes 8:60-3. 2001..One of the greatest challenges in confirming or refuting a role for herpesviruses in chronic diseases is their ubiquitous nature. It is stated from the outset that the associations described here remain controversial...
- Clinical manifestations and treatment considerations of herpes simplex virus infectionAnthony Simmons
Children s Hospital, University of Texas Medical Branch at Galveston, Galveston, TX 77555 0373, USA
J Infect Dis 186:S71-7. 2002..This review extends contemporary thinking about how new antiherpetic drugs might be put to greater therapeutic use in the future...
- Use of recombinant lentivirus pseudotyped with vesicular stomatitis virus glycoprotein G for efficient generation of human anti-cancer chimeric T cells by transduction of human peripheral blood lymphocytes in vitroAnthony Simmons
Department of Pediatrics, University of Texas Medical Branch, Galveston, Texas, USA
Virol J 3:8. 2006..To redirect human peripheral blood lymphocytes (PBLs) with a chimeric T cell receptor (chTCR) so that they recognize a new target requires a high degree of transfection efficiency, a process that is regarded as technically demanding...
- Use of a lentivirus/VSV pseudotype virus for highly efficient genetic redirection of human peripheral blood lymphocytesAnthony Simmons
Division of Virology, Children s Hospital, 301 University Boulevard, Galveston, Texas 77555 0372, USA
Nat Protoc 1:2688-700. 2006..Here we describe a highly efficient protocol that uses a lentivirus/vesicular stomatitis virus pseudotyped virus to engineer CD3/CD28-stimulated human peripheral blood cells (i.e., primarily T cells), with near 100% efficiency...
- Prevention of genital herpes in a guinea pig model using a glycoprotein D-specific single chain antibody as a microbicideJianmin Chen
University of Texas Medical Branch, Galveston, Texas, USA
Virol J 1:11. 2004..Further, the results predict that bacterial expression of active single chain antibodies can be optimized to manufacture inexpensively a useful microbicidal product active against HSV...
- Impaired clearance of herpes simplex virus type 1 from mice lacking CD1d or NKT cells expressing the semivariant V alpha 14-J alpha 281 TCRBranka Grubor-Bauk
Infectious Diseases Laboratories, Institute of Medical and Veterinary Science, Adelaide, SA, Australia
J Immunol 170:1430-4. 2003..In J alpha 281 GKO mice there was also impairment of virus clearance, resembling that seen in CD1 GKO mice. These results imply roles for the V alpha 14-J alpha 281 subset of NKT cells and for CD1d in control of HSV infection...
- Herpes simplex virus infection of murine sensory ganglia induces proliferation of neuronal satellite cellsKaren Elson
Herpes Research Laboratory, Institute of Medical and Veterinary Science, Frome Road, Adelaide, SA 5000, Australia
J Gen Virol 84:1079-84. 2003..We report that during acute ganglionic HSV infection there is a substantial increase in SC numbers. We suggest that SC proliferation in response to HSV infection may occur in order to facilitate neuronal survival...