Research Topics
| Anthony SimmonsSummaryAffiliation: University of Texas Medical Branch Country: USA Publications
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Detail Information
Publications
Herpesvirus and multiple sclerosisA Simmons
Department of Pediatrics, Sealy Center for Vaccine Development, University of Texas Medical Branch, 301 University Boulevard, Galveston, TX 77555 0739, USA
Herpes 8:60-3. 2001..One of the greatest challenges in confirming or refuting a role for herpesviruses in chronic diseases is their ubiquitous nature. It is stated from the outset that the associations described here remain controversial...
Clinical manifestations and treatment considerations of herpes simplex virus infectionAnthony Simmons
Children s Hospital, University of Texas Medical Branch at Galveston, Galveston, TX 77555 0373, USA
J Infect Dis 186:S71-7. 2002..This review extends contemporary thinking about how new antiherpetic drugs might be put to greater therapeutic use in the future...
Use of recombinant lentivirus pseudotyped with vesicular stomatitis virus glycoprotein G for efficient generation of human anti-cancer chimeric T cells by transduction of human peripheral blood lymphocytes in vitroAnthony Simmons
Department of Pediatrics, University of Texas Medical Branch, Galveston, Texas, USA
Virol J 3:8. 2006..To redirect human peripheral blood lymphocytes (PBLs) with a chimeric T cell receptor (chTCR) so that they recognize a new target requires a high degree of transfection efficiency, a process that is regarded as technically demanding...
Use of a lentivirus/VSV pseudotype virus for highly efficient genetic redirection of human peripheral blood lymphocytesAnthony Simmons
Division of Virology, Children s Hospital, 301 University Boulevard, Galveston, Texas 77555 0372, USA
Nat Protoc 1:2688-700. 2006..Here we describe a highly efficient protocol that uses a lentivirus/vesicular stomatitis virus pseudotyped virus to engineer CD3/CD28-stimulated human peripheral blood cells (i.e., primarily T cells), with near 100% efficiency...
Prevention of genital herpes in a guinea pig model using a glycoprotein D-specific single chain antibody as a microbicideJianmin Chen
University of Texas Medical Branch, Galveston, Texas, USA
Virol J 1:11. 2004..Further, the results predict that bacterial expression of active single chain antibodies can be optimized to manufacture inexpensively a useful microbicidal product active against HSV...
Impaired clearance of herpes simplex virus type 1 from mice lacking CD1d or NKT cells expressing the semivariant V alpha 14-J alpha 281 TCRBranka Grubor-Bauk
Infectious Diseases Laboratories, Institute of Medical and Veterinary Science, Adelaide, SA, Australia
J Immunol 170:1430-4. 2003..In J alpha 281 GKO mice there was also impairment of virus clearance, resembling that seen in CD1 GKO mice. These results imply roles for the V alpha 14-J alpha 281 subset of NKT cells and for CD1d in control of HSV infection...
Herpes simplex virus infection of murine sensory ganglia induces proliferation of neuronal satellite cellsKaren Elson
Herpes Research Laboratory, Institute of Medical and Veterinary Science, Frome Road, Adelaide, SA 5000, Australia
J Gen Virol 84:1079-84. 2003..We report that during acute ganglionic HSV infection there is a substantial increase in SC numbers. We suggest that SC proliferation in response to HSV infection may occur in order to facilitate neuronal survival...
