Research Topics
| Faye S SilversteinSummaryAffiliation: University of Michigan Country: USA Publications
| Collaborators
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Detail Information
Publications
Improving the treatment of neonatal seizures: National Institute of Neurological Disorders and Stroke workshop reportFaye S Silverstein
Department of Pediatrics and Neurology University of Michigan, Ann Arbor, MI, USA
J Pediatr 153:12-5. 2008
Neonatal seizuresFaye S Silverstein
Department of Pediatrics, University of Michigan, Ann Arbor, MI 48109 0646, USA
Ann Neurol 62:112-20. 2007....
Phenobarbital augments hypothermic neuroprotectionJohn D Barks
Departments of Pediatrics and Neurology, University of Michigan, Ann Arbor, Michigan 48109, USA
Pediatr Res 67:532-7. 2010..05). These results suggest that early posthypoxia-ischemia administration of phenobarbital may augment the neuroprotective efficacy of therapeutic hypothermia...
Bumetanide augments the neuroprotective efficacy of phenobarbital plus hypothermia in a neonatal hypoxia-ischemia modelYiQing Liu
Department of Pediatrics, University of Michigan, Ann Arbor, Michigan, USA
Pediatr Res 71:559-65. 2012..We evaluated whether BUM influenced the neuroprotective efficacy of combination treatment with PB and HT...
Neonatal seizures: multicenter variability in current treatment practicesAgnes I Bartha
Department of Pediatrics, University of California at San Francisco, San Francisco, California 94143 0663, and Legacy Emanuel Children s Hospital, Portland, OR, USA
Pediatr Neurol 37:85-90. 2007..Trials of anticonvulsants with long-term neurodevelopmental follow-up are needed to develop evidence-based treatment guidelines...
In-hospital versus out-of-hospital pediatric cardiac arrest: a multicenter cohort studyFrank W Moler
Children s Hospital Medical Center, University of Cincinnati, Cincinnati, OH, USA
Crit Care Med 37:2259-67. 2009....
Off-label use of antiepileptic drugs for the treatment of neonatal seizuresFaye S Silverstein
Department of Pediatrics and Neurology, University of Michigan, Ann Arbor, Michigan 48109 5646, USA
Pediatr Neurol 39:77-9. 2008..These results highlight the urgent need for rigorous clinical trials to understand the risks and benefits of new drug therapies for neonatal seizures...
Hypoxic-ischemic injury stimulates subventricular zone proliferation and neurogenesis in the neonatal ratJennifer Ong
Department of Pediatrics, University of Michigan, Ann Arbor, MI 48109, USA
Pediatr Res 58:600-6. 2005..Identification of the trophic factors that enhance maturation and survival of immature neurons could provide important clues for improving recovery after neonatal brain injury...
Neonatal hypoxic-ischemic injury increases forebrain subventricular zone neurogenesis in the mouseJennifer M Plane
Department of Pediatrics, University of Michigan Medical Center, Ann Arbor, MI 48109, USA
Neurobiol Dis 16:585-95. 2004..These results suggest that augmenting SVZ neuroblast recruitment and survival may improve neural repair after neonatal brain injury...
Topiramate extends the therapeutic window for hypothermia-mediated neuroprotection after stroke in neonatal ratsYiQing Liu
Department of Pediatrics, University of Michigan, Ann Arbor, Mich, USA
Stroke 35:1460-5. 2004..001); trends were similar at P35. CONCLUSIONS: Our data provide the impetus for further evaluation of therapeutic approaches that combine drug therapy with delayed-onset cooling after neonatal HI brain injury...
Complement activation contributes to hypoxic-ischemic brain injury in neonatal ratsRita M Cowell
Department of Neurology, University of Michigan, Ann Arbor, Michigan 48109, USA
J Neurosci 23:9459-68. 2003....
Hypoxic-ischemic injury induces macrophage inflammatory protein-1alpha expression in immature rat brainRita M Cowell
Department of Pediatrics, University of Michigan, Ann Arbor, Mich, USA
Stroke 33:795-801. 2002..CONCLUSIONS: These data implicate MIP-1alpha as a mediator of the complex and sustained inflammatory response initiated by perinatal HI braininjury...
Microglial expression of chemokine receptor CCR5 during rat forebrain development and after perinatal hypoxia-ischemiaRita M Cowell
Department of Neurology, University of Michigan Medical School, Ann Arbor, MI 48109, USA
J Neuroimmunol 173:155-65. 2006..These data implicate CCR5 in microglial recruitment and activation during brain development and after neonatal brain injury...
Impact of indolent inflammation on neonatal hypoxic-ischemic brain injury in miceJohn D E Barks
Departments of Pediatrics and Neurology, University of Michigan Medical School, Ann Arbor, MI 48109, USA
Int J Dev Neurosci 26:57-65. 2008..The results of the present study demonstrate that systemic inflammation influences the evolution of tissue injury after neonatal cerebral hypoxia-ischemia and may also impair potential recovery mechanisms...
Hypoxic-ischemic oligodendroglial injury in neonatal rat brainYiQing Liu
Department of Pediatrics, University of Michigan, Ann Arbor, Michigan 48109-0646, USA
Pediatr Res 51:25-33. 2002..Most importantly, we show that in this neonatal rodent stroke model, restoration of myelin proteins occurs after moderate, but not after more severe, cerebral hypoxia-ischemia...
New oligodendrocytes are generated after neonatal hypoxic-ischemic brain injury in rodentsAliya U Zaidi
Department of Anatomy and Cell Biology, Wayne State University School of Medicine, Detroit, Michigan 48201, USA
Glia 46:380-90. 2004..Although the neonatal brain undergoes massive cell death and atrophy the first week after injury, it retains the potential to generate new OLGs up to 4 weeks after injury within and surrounding the infarct...
Plasticity of neurons and glia following neonatal hypoxic-ischemic brain injury in ratsRobert P Skoff
Department of Anatomy and Cell Biology, Wayne State University School of Medicine, 540 E Canfield, Detroit, MI 48201, USA
Neurochem Res 32:331-42. 2007..While massive destruction of neurons and glia are striking events shortly after brain HI, neural cells re-express their intrinsic properties and attempt an anatomical recovery long after injury...
