Faye S Silverstein
Affiliation: University of Michigan
- Improving the treatment of neonatal seizures: National Institute of Neurological Disorders and Stroke workshop reportFaye S Silverstein
Department of Pediatrics and Neurology University of Michigan, Ann Arbor, MI, USA
J Pediatr 153:12-5. 2008
- Neonatal seizuresFaye S Silverstein
Department of Pediatrics, University of Michigan, Ann Arbor, MI 48109 0646, USA
Ann Neurol 62:112-20. 2007....
- Phenobarbital augments hypothermic neuroprotectionJohn D Barks
Departments of Pediatrics and Neurology, University of Michigan, Ann Arbor, Michigan 48109, USA
Pediatr Res 67:532-7. 2010..05). These results suggest that early posthypoxia-ischemia administration of phenobarbital may augment the neuroprotective efficacy of therapeutic hypothermia...
- Docosahexaenoic acid augments hypothermic neuroprotection in a neonatal rat asphyxia modelDeborah R Berman
Division of Maternal Fetal Medicine, Department of Obstetrics and Gynecology, University of Michigan, Ann Arbor, Mich, USA
Neonatology 104:71-8. 2013..In neonatal rats, early post-hypoxia-ischemia (HI) administration of the omega-3 fatty acid docosahexaenoic acid (DHA) improves sensorimotor function, but does not attenuate brain damage...
- Bumetanide augments the neuroprotective efficacy of phenobarbital plus hypothermia in a neonatal hypoxia-ischemia modelYiQing Liu
Department of Pediatrics, University of Michigan, Ann Arbor, Michigan, USA
Pediatr Res 71:559-65. 2012..We evaluated whether BUM influenced the neuroprotective efficacy of combination treatment with PB and HT...
- Neonatal seizures: multicenter variability in current treatment practicesAgnes I Bartha
Department of Pediatrics, University of California at San Francisco, San Francisco, California 94143 0663, and Legacy Emanuel Children s Hospital, Portland, OR, USA
Pediatr Neurol 37:85-90. 2007..Trials of anticonvulsants with long-term neurodevelopmental follow-up are needed to develop evidence-based treatment guidelines...
- In-hospital versus out-of-hospital pediatric cardiac arrest: a multicenter cohort studyFrank W Moler
Children s Hospital Medical Center, University of Cincinnati, Cincinnati, OH, USA
Crit Care Med 37:2259-67. 2009....
- Off-label use of antiepileptic drugs for the treatment of neonatal seizuresFaye S Silverstein
Department of Pediatrics and Neurology, University of Michigan, Ann Arbor, Michigan 48109 5646, USA
Pediatr Neurol 39:77-9. 2008..These results highlight the urgent need for rigorous clinical trials to understand the risks and benefits of new drug therapies for neonatal seizures...
- Hypoxic-ischemic injury stimulates subventricular zone proliferation and neurogenesis in the neonatal ratJennifer Ong
Department of Pediatrics, University of Michigan, Ann Arbor, MI 48109, USA
Pediatr Res 58:600-6. 2005..Identification of the trophic factors that enhance maturation and survival of immature neurons could provide important clues for improving recovery after neonatal brain injury...
- Neonatal hypoxic-ischemic injury increases forebrain subventricular zone neurogenesis in the mouseJennifer M Plane
Department of Pediatrics, University of Michigan Medical Center, Ann Arbor, MI 48109, USA
Neurobiol Dis 16:585-95. 2004..These results suggest that augmenting SVZ neuroblast recruitment and survival may improve neural repair after neonatal brain injury...
- Topiramate extends the therapeutic window for hypothermia-mediated neuroprotection after stroke in neonatal ratsYiQing Liu
Department of Pediatrics, University of Michigan, Ann Arbor, Mich, USA
Stroke 35:1460-5. 2004..We evaluated whether treatment with topiramate, a clinically available anticonvulsant, increased the efficacy of delayed post-HI hypothermia in a neonatal rat stroke model...
- Complement activation contributes to hypoxic-ischemic brain injury in neonatal ratsRita M Cowell
Department of Neurology, University of Michigan, Ann Arbor, Michigan 48109, USA
J Neurosci 23:9459-68. 2003....
- Hypoxic-ischemic injury induces macrophage inflammatory protein-1alpha expression in immature rat brainRita M Cowell
Department of Pediatrics, University of Michigan, Ann Arbor, Mich, USA
Stroke 33:795-801. 2002..We evaluated the impact of acute hypoxic-ischemic (HI) brain injury on the expression of MIP-1alpha in neonatal rat brain...
- Microglial expression of chemokine receptor CCR5 during rat forebrain development and after perinatal hypoxia-ischemiaRita M Cowell
Department of Neurology, University of Michigan Medical School, Ann Arbor, MI 48109, USA
J Neuroimmunol 173:155-65. 2006..These data implicate CCR5 in microglial recruitment and activation during brain development and after neonatal brain injury...
- Rationale, timeline, study design, and protocol overview of the therapeutic hypothermia after pediatric cardiac arrest trialsFrank W Moler
1Department of Pediatrics, University of Michigan, Ann Arbor, MI 2Department of Pediatrics, Wayne State University, Detroit, MI 3Department of Pediatrics, University of Utah, Salt Lake City, UT 4Department of Neuropsychology, Kennedy Krieger Institute, Baltimore, MD 5Department of Pediatric Rehabilitation Medicine, Kennedy Krieger Institute, Baltimore, MD
Pediatr Crit Care Med 14:e304-15. 2013..To describe the rationale, timeline, study design, and protocol overview of the Therapeutic Hypothermia after Pediatric Cardiac Arrest trials...
- Impact of indolent inflammation on neonatal hypoxic-ischemic brain injury in miceJohn D E Barks
Departments of Pediatrics and Neurology, University of Michigan Medical School, Ann Arbor, MI 48109, USA
Int J Dev Neurosci 26:57-65. 2008..The results of the present study demonstrate that systemic inflammation influences the evolution of tissue injury after neonatal cerebral hypoxia-ischemia and may also impair potential recovery mechanisms...
- Hypoxic-ischemic oligodendroglial injury in neonatal rat brainYiQing Liu
Department of Pediatrics, University of Michigan, Ann Arbor, Michigan 48109 0646, USA
Pediatr Res 51:25-33. 2002..Most importantly, we show that in this neonatal rodent stroke model, restoration of myelin proteins occurs after moderate, but not after more severe, cerebral hypoxia-ischemia...
- New oligodendrocytes are generated after neonatal hypoxic-ischemic brain injury in rodentsAliya U Zaidi
Department of Anatomy and Cell Biology, Wayne State University School of Medicine, Detroit, Michigan 48201, USA
Glia 46:380-90. 2004..Although the neonatal brain undergoes massive cell death and atrophy the first week after injury, it retains the potential to generate new OLGs up to 4 weeks after injury within and surrounding the infarct...
- Plasticity of neurons and glia following neonatal hypoxic-ischemic brain injury in ratsRobert P Skoff
Department of Anatomy and Cell Biology, Wayne State University School of Medicine, 540 E Canfield, Detroit, MI 48201, USA
Neurochem Res 32:331-42. 2007..While massive destruction of neurons and glia are striking events shortly after brain HI, neural cells re-express their intrinsic properties and attempt an anatomical recovery long after injury...