Research Topics
| Marian D SigmanSummaryAffiliation: University of California Country: USA Publications
Research Grants
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Detail Information
Publications
Improvement in cognitive and language skills from preschool to adolescence in autismMarian Sigman
Department of Psychiatry, UCLA School of Medicine, 760 Westwood Plaza, Room 68 237, Los Angeles, CA, 90095 1759, USA
J Autism Dev Disord 35:15-23. 2005..Early childhood predictors of language skills in adolescence were functional play skills, responsiveness to others' bids for joint attention, and the frequency of requesting behaviors...- IQ on the rise: the Flynn effect in rural Kenyan childrenTamara C Daley
Department of Psychology, University of California, Los Angeles 90095 1563, USA
Psychol Sci 14:215-9. 2003..The hypotheses that resonate best with our findings are those related to parents' literacy, family structure, and children's nutrition and health... - Diagnostic conceptualization of autism among Indian psychiatrists, psychologists, and pediatriciansTamara C Daley
Department of Psychology, University of California Los Angeles, 90095 1563, USA
J Autism Dev Disord 32:13-23. 2002..Comparisons with DSM-III and DSM-IV criteria suggest that Indian professionals may adhere to these systems. Conclusions about diagnosis in a cultural context and areas for future research are suggested... - Autism from developmental and neuropsychological perspectivesMarian Sigman
Department of Psychiatry and Biobehavioral Sciences, David Geffen School of Medicine, University of California, Los Angeles, California 90095, USA
Annu Rev Clin Psychol 2:327-55. 2006.... 
Autistic disorder associated with a paternally derived unbalanced translocation leading to duplication of chromosome 15pter-q13.2: a case reportDavid J Wu
Department of Biological Sciences, University of Delaware, Newark, USA
Mol Cytogenet 2:27. 2009..This case suggests that biallelically expressed genes on proximal 15q contribute to the idic(15) autism phenotype...- Play and developmental outcomes in infant siblings of children with autismLisa Christensen
Department of Psychology, University of California, Los Angeles, 1237 Franz Hall, Los Angeles, CA 90095 1563, USA
J Autism Dev Disord 40:946-57. 2010..Group differences disappeared with the inclusion of verbal mental age. Play as an early indicator of autism and its relationship to the broader autism phenotype is discussed... - Multiple forms of atypical rearrangements generating supernumerary derivative chromosome 15Nicholas J Wang
Nemours Biomedical Research, Alfred I, duPont Hospital for Children, Wilmington, Delaware, 19803, USA
BMC Genet 9:2. 2008..Five recurrent breakpoints have been described in most cases of segmental aneuploidy of chromosome 15q11-q13 and previous studies have shown that most idic(15) chromosomes arise through BP3:BP3 or BP4:BP5 recombination events... - Early detection of core deficits in autismMarian Sigman
University of California at Los Angeles, Psychiatry Biobehavioral Sci Psych Dev, Box 95175759, 68 237 NPI, Los Angeles, CA 90095, USA
Ment Retard Dev Disabil Res Rev 10:221-33. 2004..The review concludes that all of these areas are worthy of investigation in young children, particularly those at higher risk of showing some of the core deficits of autism such as the infant siblings of children with autism... - Diet quality affects the playground activities of Kenyan childrenMarian Sigman
Department of Psychiatry, School of Medicine, University of California, Los Angeles, CA 90095 1759, USA
Food Nutr Bull 26:S202-12. 2005..These results support our previous findings from naturalistic studies in the same community that both diet quantity and quality are important for children's development... 
Modeling longitudinal change in the language abilities of children with autism: parent behaviors and child characteristics as predictors of changeMichael Siller
Department of Psychology, University of California, Los Angeles, USA
Dev Psychol 44:1691-704. 2008..These findings support a social?pragmatic view on language acquisition, which emphasizes the collaborative process through which children and their parents negotiate shared meaning...- Neural basis of irony comprehension in children with autism: the role of prosody and contextA Ting Wang
Department of Psychology, University of California, Los Angeles, CA, USA
Brain 129:932-43. 2006.... - Social and cardiac responses of young children with autismMarian Sigman
Department of Psychiatry, University of California at Los Angles, School of Medicine, 90095-1752, USA
Autism 7:205-16. 2003..The findings suggest that the lack of social attention often demonstrated by children with autism does not stem from increased arousal in social situations. An alternative explanation is considered... - Reading affect in the face and voice: neural correlates of interpreting communicative intent in children and adolescents with autism spectrum disordersA Ting Wang
Department of Psychiatry, University of California, Los Angeles, USA
Arch Gen Psychiatry 64:698-708. 2007..However, there is also evidence that activity in key regions can be increased if task demands allow for explicit processing of emotion... - Neural correlates of facial affect processing in children and adolescents with autism spectrum disorderA Ting Wang
Department of Psychology, UCLA, Los Angeles, CA, USA
J Am Acad Child Adolesc Psychiatry 43:481-90. 2004..High-functioning individuals with ASD may be relatively unimpaired in the cognitive assessment of basic emotions, yet still show differences in the automatic processing of facial expressions... - Interactions between mothers and children: impacts of maternal and child anxietyPhoebe S Moore
Department of Psychology, University of California, Los Angeles, Los Angeles, CA, USA
J Abnorm Psychol 113:471-6. 2004..01), with anxious mothers and nonanxious mothers of anxious children likely to catastrophize. Theoretical and research implications are discussed... - Frontal contributions to face processing differences in autism: evidence from fMRI of inverted face processingSusan Y Bookheimer
Department of Psychiatry and Biobehavioral Sciences, David Geffen School of Medicine, University of California Los Angeles, Los Angeles, California 90095, USA
J Int Neuropsychol Soc 14:922-32. 2008..Our results are consistent with other recent studies implicating frontal and limbic dysfunction during face processing in autism... - One-year follow-up of family versus child CBT for anxiety disorders: Exploring the roles of child age and parental intrusivenessJeffrey J Wood
UCLA, Los Angeles, CA, USA
Child Psychiatry Hum Dev 40:301-16. 2009..To compare the relative long-term benefit of family-focused cognitive behavioral therapy (FCBT) and child-focused cognitive behavioral therapy (CCBT) for child anxiety disorders at a 1-year follow-up... - Mothers' narratives regarding their child with autism predict maternal synchronous behavior during playTed Hutman
Department of Psychiatry and Bio behavioral Science, University of California, Los Angeles, CA 90095 1759, USA
J Child Psychol Psychiatry 50:1255-63. 2009..This study sought to explain individual differences in maternal synchrony in order to improve parent-training programs targeting communication skills in children with autism... - Head circumference and height in autism: a study by the Collaborative Program of Excellence in AutismJanet E Lainhart
Department of Psychiatry, The Brain Institute at the University of Utah, Salt Lake City, Utah 84108, USA
Am J Med Genet A 140:2257-74. 2006..The wide distribution of head circumference in autism has major implications for genetic, neuroimaging, and other neurobiological research... - Intergenerational benefits of family-based HIV interventionsMary Jane Rotheram-Borus
Center for Community Health, University of California, Los Angeles, CA 90024, USA
J Consult Clin Psychol 74:622-7. 2006..These results suggest that there are possibly long-term, intergenerational benefits of an intervention for families coping with HIV... - Knowledge about condoms among low-income pregnant Latina adolescents in relation to explicit maternal discussion of contraceptivesErum Nadeem
UCLA Health Services Research Center, University of California, Los Angeles, Los Angeles, California 90024 6505, USA
J Adolesc Health 39:119.e9-15. 2006..To examine pregnant adolescents' conceptual knowledge about condom use and its relation to maternal implicit and explicit communication about contraceptives... - The behaviors of parents of children with autism predict the subsequent development of their children's communicationMichael Siller
Department of Psychiatry, University of California, Los Angeles 90024 1759, USA
J Autism Dev Disord 32:77-89. 2002..These findings suggest a developmental link between parental sensitivity and the child's subsequent development of communication skills in children with autism. Implications for parent training interventions are discussed... - A longitudinal study of maternal messages about dating and sexuality and their influence on Latino adolescentsLaura F Romo
Departments of Child and Adolescent Development and Chicano Studies, California State University, Northridge, California, USA
J Adolesc Health 31:59-69. 2002..To learn more about the nature of mother-adolescent discussions about sexuality and their influence on adolescents' behaviors and attitudes in Latino families... - Parenting and childhood anxiety: theory, empirical findings, and future directionsJeffrey J Wood
Department of Psychology, University of California, Los Angeles 90095, USA
J Child Psychol Psychiatry 44:134-51. 2003..Improved methodological designs are proposed, including the use of repeated-measure and experimental designs for examining the direction of effects... - Animal source foods improve dietary quality, micronutrient status, growth and cognitive function in Kenyan school children: background, study design and baseline findingsCharlotte G Neumann
Department of Community Health Sciences and Pediatrics, Schools of Public Health and Medicine, University of California, Los Angeles, CA, USA
J Nutr 133:3941S-3949S. 2003..Hierarchical linear random effects modeling was used for analysis of outcomes... - The impact of dietary intervention on the cognitive development of Kenyan school childrenShannon E Whaley
Department of Psychiatry and Psychology, Neuropsychiatric Institute, University of California, Los Angeles, CA, USA
J Nutr 133:3965S-3971S. 2003..Implications of these findings for supplementation programs in developing countries are discussed... - Understanding emotions in others: mirror neuron dysfunction in children with autism spectrum disordersMirella Dapretto
Ahmanson Lovelace Brain Mapping Center, Semel Institute for Neuroscience and Human Behavior, Department of Psychiatry and Biobehavioral Sciences, David Geffen School of Medicine, University of California Los Angeles, 90095, USA
Nat Neurosci 9:28-30. 2006..Notably, activity in this area was inversely related to symptom severity in the social domain, suggesting that a dysfunctional 'mirror neuron system' may underlie the social deficits observed in autism... - Family cognitive behavioral therapy for child anxiety disordersJeffrey J Wood
Department of Education, University of California, Los Angeles 90095, USA
J Am Acad Child Adolesc Psychiatry 45:314-21. 2006..This study compared family-focused cognitive behavioral therapy (CBT; the Building Confidence Program) with traditional child-focused CBT with minimal family involvement for children with anxiety disorders... - Response to distress in infants at risk for autism: a prospective longitudinal studyTed Hutman
UCLA Center for Autism Research and Treatment, Semel Institute for Neuroscience and Human Behavior, University of California, Los Angeles, Los Angeles, CA 90095 1759, USA
J Child Psychol Psychiatry 51:1010-20. 2010..This deficit is expected to disrupt social interactions, social learning, and the formation of close relationships. Response to distress has not been evaluated previously in infants with ASD earlier than 18 months of age... - Continuity and change from early childhood to adolescence in autismCorina W McGovern
University of California at Los Angeles, CA 90095-1759, USA
J Child Psychol Psychiatry 46:401-8. 2005..Thus, any early intervention that impacts the cognitive abilities of young children with autism is likely to have a parallel influence on their social skills as they mature into late adolescence and early adulthood... - No neural evidence of statistical learning during exposure to artificial languages in children with autism spectrum disordersAshley A Scott-Van Zeeland
Semel Institute for Neuroscience and Human Behavior, University of California, Los Angeles, California, USA
Biol Psychiatry 68:345-51. 2010..Importantly, early word segmentation skills have been shown to predict later language development in typically developing (TD) children... - Genome-wide expression profiling of lymphoblastoid cell lines distinguishes different forms of autism and reveals shared pathwaysYuhei Nishimura
Center for Autism Research and Treatment, Semel Institute for Neuroscience and Human Behavior, David Geffen School of Medicine, University of California Los Angeles, Los Angeles, CA 90095, USA
Hum Mol Genet 16:1682-98. 2007..These results provide evidence that blood derived lymphoblastoid cells gene expression is likely to be useful for identifying etiological subsets of autism and exploring its pathophysiology...
Research Grants
- Children's Anxiety Regulation and Maternal CommunicationMarian Sigman; Fiscal Year: 2002....
- DETERMINANTS OF SOCIAL COMMUNICATION SKILLS IN AUTISMMarian Sigman; Fiscal Year: 2006....
- Social & Language Deficits in Autism-Biology & TreamentMarian Sigman; Fiscal Year: 2007..abstract_text> ..