Research Topics
Species | A SiderowfSummaryAffiliation: University of Pennsylvania Country: USA Publications
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Detail Information
Publications
Parkinson's disease: clinical features, epidemiology and geneticsA Siderowf
Parkinson s Disease and Movement Disorders Center, University of Pennsylvania, Philadelphia, Pennsylvania 19107, USA
Neurol Clin 19:565-78, vi. 2001..This article reviews the clinical features, epidemiology and genetics of PD, with emphasis on insights from recent genetic and epidemiological studies...
Premotor Parkinson's disease: concepts and definitionsAndrew Siderowf
Parkinson s Disease and Mov Disord Center, Department of Neurology, University of Pennsylvania, Philadelphia, Pennsylvania, USA
Mov Disord 27:608-16. 2012....- CSF amyloid {beta} 1-42 predicts cognitive decline in Parkinson diseaseA Siderowf
Department of Neurology, 330 South 9th Street, Second Floor, Philadelphia, PA 19107, USA
Neurology 75:1055-61. 2010..Cognitive decline associated with Parkinson disease (PD) is common and highly disabling. Biomarkers that help identify patients at risk for cognitive decline would be useful additions to the clinical management of the disease... - [99mTc]TRODAT-1 SPECT imaging correlates with odor identification in early Parkinson diseaseA Siderowf
Parkinson Disease and Movement Disorders Center, Department of Neurology, University of Pennsylvania, Philadelphia, USA
Neurology 64:1716-20. 2005..In vivo imaging of the dopamine transporter with [99mTc]TRODAT-1 (TRODAT) and olfactory testing have both been proposed as potential biomarkers in Parkinson disease (PD)... - Cognitive performance of GBA mutation carriers with early-onset PD: the CORE-PD studyR N Alcalay
Department of Neurology, College of Physicians and Surgeons, Columbia University, New York, NY, USA
Neurology 78:1434-40. 2012..To assess the cognitive phenotype of glucocerebrosidase (GBA) mutation carriers with early-onset Parkinson disease (PD)... - The relation between depression and parkin genotype: the CORE-PD studyA Srivastava
Department of Neurology, College of Physicians and Surgeons, Columbia University, New York, NY, USA
Parkinsonism Relat Disord 17:740-4. 2011..Genetic factors for depression are similarly not well characterized. We investigate the role of parkin mutations in depression among those with EOPD and their relatives... - Novel CSF biomarkers for frontotemporal lobar degenerationsW T Hu
Department of Neurology, University of Pennsylvania School of Medicine, Philadelphia 19104 4283, USA
Neurology 75:2079-86. 2010..To identify antemortem CSF diagnostic biomarkers that can potentially distinguish between the 2 main causes of frontotemporal lobar degeneration (FTLD), i.e., FTLD with TDP-43 pathology (FTLD-TDP) and FTLD with tau pathology (FTLD-tau)... - Interest in predictive testing for Parkinson's disease: impact of neuroprotective therapyN Dahodwala
Department of Neurology, Pennsylvania Hospital, University of Pennsylvania, USA
Parkinsonism Relat Disord 13:495-9. 2007..001). Interest in predictive testing for PD is moderate in the absence of effective therapy, and goes up significantly when both clinical trial participation and neuroprotective therapy are offered... - Multiple pathologies in a patient with a progressive neurodegenerative syndromeT W Liang
Neurology, University of Pennsylvania School of Medicine, Philadelphia, PA, USA
J Neurol Neurosurg Psychiatry 76:252-5. 2005..This case raises the possibility that three distinct neuropathological diagnoses share a common aetiology... - Olfaction in Parkin heterozygotes and compound heterozygotes: the CORE-PD studyR N Alcalay
Department of Neurology, College of Physicians and Surgeons, Columbia University, New York, NY 10032, USA
Neurology 76:319-26. 2011..Whether olfaction differs between Parkin mutation heterozygotes and carriers of 2 Parkin mutations (compound heterozygotes) is unknown... - Postural change of forced vital capacity predicts some respiratory symptoms in ALSJ Varrato
Department of Neurology, University of Pennsylvania, Philadelphia, USA
Neurology 57:357-9. 2001..The supine FVC is significantly lower and the erect--supine FVC difference is significantly greater in patients with complaints of dyspnea, orthopnea, and daytime fatigue... - Diagnostic accuracy of [99mTc]TRODAT-1 SPECT imaging in early Parkinson's diseaseK L Chou
Parkinson s Disease and Movement Disorders Center, University of Pennsylvania School of Medicine, Pennsylvania Hospital, 330 South Ninth Street, Philadelphia, PA 19107, USA
Parkinsonism Relat Disord 10:375-9. 2004..79, specificity 0.92). These findings show that TRODAT imaging can accurately differentiate early PD patients from controls and has the potential to improve the diagnosis of patients with early signs of PD... - Venous thrombosis in an ALS population over four yearsL B Elman
Penn Neurological Institute, 330 South 9th Street, University of Pennsylvania, Philadelphia, PA 19107, USA
Amyotroph Lateral Scler Other Motor Neuron Disord 6:246-9. 2005..Immobility was significantly associated with increased risk of venous thrombosis (RR = 4.96; 95% CI 1.39-17.78)... - Emergence of complex, involuntary movements after gamma knife radiosurgery for essential tremorA Siderowf
Department of Neurology, University of Pennsylvania, School of Medicine, Philadelphia, Pennsylvania 19104, USA
Mov Disord 16:965-7. 2001..This case illustrates the need for long-term follow-up to fully evaluate the potential for complications following radiosurgery... - Projected number of people with Parkinson disease in the most populous nations, 2005 through 2030E R Dorsey
Department of Neurology, University of Rochester Medical Center, 1351 Mt Hope Blvd, Suite 223, Rochester, NY 14620, USA
Neurology 68:384-6. 2007..The number of individuals with PD over age 50 in these countries was between 4.1 and 4.6 million in 2005 and will double to between 8.7 and 9.3 million by 2030...