N L Sicotte
Affiliation: University of California
- Neuroimaging in multiple sclerosis: neurotherapeutic implicationsNancy L Sicotte
Division of Brain Mapping, Department of Neurology, David Geffen School of Medicine at UCLA, Los Angeles, California 90095, USA
Neurotherapeutics 8:54-62. 2011....
- Onset of multiple sclerosis associated with anti-TNF therapyN L Sicotte
Division of Brain Mapping, UCLA School of Medicine, Los Angeles, CA, USA
Neurology 57:1885-8. 2001..We report a patient with new onset MS closely associated with the initiation of anti-TNF therapy for juvenile rheumatoid arthritis. It is possible that the inhibition of TNF triggered MS in this individual...
- Regional hippocampal atrophy in multiple sclerosisN L Sicotte
Department of Neurology, David Geffen School of Medicine at UCLA, Los Angeles, CA 90095, USA
Brain 131:1134-41. 2008..Further understanding of this process could provide targets for therapeutic interventions including neuroprotective treatments...
- Diffusion tensor MRI shows abnormal brainstem crossing fibers associated with ROBO3 mutationsN L Sicotte
Department of Neurology, Division of Brain Mapping, Interdepartmental Programs, UCLA, USA
Neurology 67:519-21. 2006..Mutations in the ROBO3 gene lead to a widespread lack of crossing fibers throughout the brainstem...
- A longitudinal fMRI study of the paced auditory serial addition taskK S Cardinal
Department of Neurology, David Geffen School of Medicine at UCLA, Los Angeles, CA, USA
Mult Scler 14:465-71. 2008....
- Detection and segmentation of pathological structures by the extended graph-shifts algorithmJason J Corso
Center for Computational Biology, Laboratory of Neuro Imaging, University of California, Los Angeles, USA
Med Image Comput Comput Assist Interv 10:985-93. 2007..We demonstrate accurate results, precision and recall in the order of 93%, and also show that the algorithm is computationally efficient, segmenting a full 3D volume in about one minute...
- Normal variants of Microcephalin and ASPM do not account for brain size variabilityRoger P Woods
Ahmanson Lovelace Brain Mapping Center, David Geffen School of Medicine, University of California, CA 90095, USA
Hum Mol Genet 15:2025-9. 2006..This result suggests that the selective pressure on these genes may be related to subtle neurobiological effects or to their expression outside the brain...
- Mutations in a human ROBO gene disrupt hindbrain axon pathway crossing and morphogenesisJoanna C Jen
Department of Neurology, University of California, Los Angeles, CA 90095, USA
Science 304:1509-13. 2004..Like its murine homolog Rig1/Robo3, but unlike other Robo proteins, ROBO3 is required for hindbrain axon midline crossing...
- Creation and use of a Talairach-compatible atlas for accurate, automated, nonlinear intersubject registration, and analysis of functional imaging dataR P Woods
Department of Neurology, Neuropsychiatric Institute, UCLA School of Medicine, Los Angeles, California 90095 7085, USA
Hum Brain Mapp 8:73-9. 1999....
- Comparison of multiple sclerosis lesions at 1.5 and 3.0 TeslaNancy L Sicotte
Department of Neurology, Division of Brain Mapping, University of California Los Angeles, Los Angeles, CA, USA
Invest Radiol 38:423-7. 2003..To evaluate the relative sensitivity of MR scanning for multiple sclerosis (MS) at 1.5 Tesla (T) and 3.0 T using identical acquisition conditions, as is typical of multicenter clinical trials...
- Treatment of multiple sclerosis with the pregnancy hormone estriolNancy L Sicotte
Department of Neurology, Reed Neurological Research Center, University of California Los Angeles, Los Angeles, CA 90095, USA
Ann Neurol 52:421-8. 2002..This novel treatment strategy of using pregnancy doses of estriol in multiple sclerosis has relevance to other autoimmune diseases that also improve during pregnancy...
- Dysregulation of IL-10 and IL-12p40 in secondary progressive multiple sclerosisSamantha S Soldan
Department of Neurology, Reed Neurological Research Center, University of California School of Medicine, 750 Westwood Plaza, Los Angeles, CA 90095, USA
J Neuroimmunol 146:209-15. 2004..Differences in immune responsiveness in RRMS and SPMS are important in the understanding of the evolution of the immunopathogenesis of the disease and for the development of disease type specific treatments...
- Testosterone treatment in multiple sclerosis: a pilot studyNancy L Sicotte
Division of Brain Mapping, Department of Neurology, The David Geffen School of Medicine at UCLA, Los Angeles, California, USA
Arch Neurol 64:683-8. 2007..To study the effect of testosterone supplementation on men with multiple sclerosis (MS)...
- Immune modulation in multiple sclerosis patients treated with the pregnancy hormone estriolSamantha S Soldan
Department of Neurology, Reed Neurological Research Center, University of California School of Medicine, Los Angeles, CA 90095, USA
J Immunol 171:6267-74. 2003..Further study of oral estriol therapy is warranted in Th1-mediated autoimmune diseases with known improvement during pregnancy...