Emma Shtivelman

Summary

Affiliation: University of California
Country: USA

Publications

  1. ncbi A role for PI 3-kinase and PKB activity in the G2/M phase of the cell cycle
    Emma Shtivelman
    Cancer Research Institute, University of California San Francisco, San Francisco, CA 94143 0128, USA
    Curr Biol 12:919-24. 2002
  2. ncbi Inhibition of Chk1 by activated PKB/Akt
    Frank W King
    Cancer Research Institute, University of California San Francisco, 94115, USA
    Cell Cycle 3:634-7. 2004
  3. ncbi Estrogen receptor β causes a G2 cell cycle arrest by inhibiting CDK1 activity through the regulation of cyclin B1, GADD45A, and BTG2
    Sreenivasan Paruthiyil
    Department of Obstetrics and Center for Reproductive Sciences, University of California, San Francisco, CA 94143, USA
    Breast Cancer Res Treat 129:777-84. 2011
  4. ncbi Promotion of mitosis by activated protein kinase B after DNA damage involves polo-like kinase 1 and checkpoint protein CHFR
    Emma Shtivelman
    Cancer Research Institute, Comprehensive Cancer Center, University of California San Francisco, San Francisco, CA 94115, USA
    Mol Cancer Res 1:959-69. 2003
  5. ncbi Inhibition of nuclear import by the proapoptotic protein CC3
    Frank W King
    Cancer Research Institute, University of California San Francisco, 94115, USA
    Mol Cell Biol 24:7091-101. 2004
  6. ncbi Phase I trial and antitumor effects of BZL101 for patients with advanced breast cancer
    Hope Rugo
    University of California, San Francisco Carol Franc Buck Breast Care Center, San Francisco, USA
    Breast Cancer Res Treat 105:17-28. 2007
  7. ncbi Multiple developmental roles of Ahnak are suggested by localization to sites of placentation and neural plate fusion in the mouse conceptus
    Karen M Downs
    Department of Anatomy, University of Wisconsin Madison Medical School, 1300 University Avenue, Madison, WI 53706, USA
    Gene Expr Patterns 2:27-34. 2002
  8. ncbi AHNAK interacts with the DNA ligase IV-XRCC4 complex and stimulates DNA ligase IV-mediated double-stranded ligation
    Thomas Stiff
    Genome Damage and Stability Centre, University of Sussex, Science Park Road, Falmer, Brighton BN1 9RQ, UK
    DNA Repair (Amst) 3:245-56. 2004
  9. ncbi Molecular mechanisms underlying selective cytotoxic activity of BZL101, an extract of Scutellaria barbata, towards breast cancer cells
    Sylvia Fong
    BioNovo, Inc, Emeryville, California 94608, USA
    Cancer Biol Ther 7:577-86. 2008

Collaborators

Detail Information

Publications9

  1. ncbi A role for PI 3-kinase and PKB activity in the G2/M phase of the cell cycle
    Emma Shtivelman
    Cancer Research Institute, University of California San Francisco, San Francisco, CA 94143 0128, USA
    Curr Biol 12:919-24. 2002
    ....
  2. ncbi Inhibition of Chk1 by activated PKB/Akt
    Frank W King
    Cancer Research Institute, University of California San Francisco, 94115, USA
    Cell Cycle 3:634-7. 2004
    ..Inhibition of these steps provides a plausible explanation for the observed attenuation of Chk1 activation by activated PKB after DNA damage...
  3. ncbi Estrogen receptor β causes a G2 cell cycle arrest by inhibiting CDK1 activity through the regulation of cyclin B1, GADD45A, and BTG2
    Sreenivasan Paruthiyil
    Department of Obstetrics and Center for Reproductive Sciences, University of California, San Francisco, CA 94143, USA
    Breast Cancer Res Treat 129:777-84. 2011
    ..These results provide evidence that drugs that stimulate the production of unliganded ERβ may be effective new therapies to prevent breast cancer...
  4. ncbi Promotion of mitosis by activated protein kinase B after DNA damage involves polo-like kinase 1 and checkpoint protein CHFR
    Emma Shtivelman
    Cancer Research Institute, Comprehensive Cancer Center, University of California San Francisco, San Francisco, CA 94115, USA
    Mol Cancer Res 1:959-69. 2003
    ..The deregulated activation of PKB that occurs frequently in tumors might inhibit CHFR activity after DNA damage and therefore promote Plk1 accumulation leading to the disruption of the DNA damage checkpoint...
  5. ncbi Inhibition of nuclear import by the proapoptotic protein CC3
    Frank W King
    Cancer Research Institute, University of California San Francisco, 94115, USA
    Mol Cell Biol 24:7091-101. 2004
    ..Significantly, a dominant-negative form of importin beta1 shown previously to inhibit multiple transport pathways induces rapid cell death, strongly indicating that inhibition of nuclear transport serves as a potent apoptotic signal...
  6. ncbi Phase I trial and antitumor effects of BZL101 for patients with advanced breast cancer
    Hope Rugo
    University of California, San Francisco Carol Franc Buck Breast Care Center, San Francisco, USA
    Breast Cancer Res Treat 105:17-28. 2007
    ..We studied mechanisms of activity and performed a phase I clinical trial in patients with advanced breast cancer to evaluate BZL101, an aqueous extract from Scutellaria barbata...
  7. ncbi Multiple developmental roles of Ahnak are suggested by localization to sites of placentation and neural plate fusion in the mouse conceptus
    Karen M Downs
    Department of Anatomy, University of Wisconsin Madison Medical School, 1300 University Avenue, Madison, WI 53706, USA
    Gene Expr Patterns 2:27-34. 2002
    ..On the basis of these observations, we suggest that Ahnak may play heretofore unrecognized roles in tissue union during normal mouse development...
  8. ncbi AHNAK interacts with the DNA ligase IV-XRCC4 complex and stimulates DNA ligase IV-mediated double-stranded ligation
    Thomas Stiff
    Genome Damage and Stability Centre, University of Sussex, Science Park Road, Falmer, Brighton BN1 9RQ, UK
    DNA Repair (Amst) 3:245-56. 2004
    ..Together, these findings demonstrate new activities for AHNAK, and raise the possibility that it may function to modulate DNA non-homologous end-joining...
  9. ncbi Molecular mechanisms underlying selective cytotoxic activity of BZL101, an extract of Scutellaria barbata, towards breast cancer cells
    Sylvia Fong
    BioNovo, Inc, Emeryville, California 94608, USA
    Cancer Biol Ther 7:577-86. 2008
    ..The promising selectivity of BZL101 towards cancer cells is based on metabolic differences between highly glycolytic tumor cells and normal cells...