Sadeep Shrestha

Summary

Affiliation: University of Alabama at Birmingham
Country: USA

Publications

  1. pmc Genomic copy number variants: evidence for association with antibody response to anthrax vaccine adsorbed
    Michael I Falola
    Department of Epidemiology, University of Alabama at Birmingham, Birmingham, Alabama, United States of America
    PLoS ONE 8:e64813. 2013
  2. pmc The utility of mitochondrial and y chromosome phylogenetic data to improve correction for population stratification
    Robert Makowsky
    Department of Biostatistics, School of Public Health, University of Alabama at Birmingham Birmingham, AL, USA
    Front Genet 3:301. 2012
  3. pmc RYR3 gene polymorphisms and cardiovascular disease outcomes in the context of antihypertensive treatment
    A I Lynch
    Department of Epidemiology, University of Alabama at Birmingham, Birmingham, AL 35294, USA
    Pharmacogenomics J 13:330-4. 2013
  4. pmc Short communication: lack of occult HIV infection among non-AIDS-defining cancer patients in three academic oncology clinics in the United States
    Sadeep Shrestha
    Department of Epidemiology, University of Alabama at Birmingham, Birmingham, AL 35294 0022, USA
    AIDS Res Hum Retroviruses 29:887-91. 2013
  5. doi request reprint Influence of host genetic and ecological factors in complex concomitant infections - relevance to sexually transmitted infections
    Sadeep Shrestha
    Department of Epidemiology, University of Alabama at Birmingham, Birmingham, AL 35294 0022, USA
    J Reprod Immunol 92:27-32. 2011
  6. pmc Replication of RYR3 gene polymorphism association with cIMT among HIV-infected whites
    Sadeep Shrestha
    Department of Epidemiology, University of Alabama at Birmingham, Birmingham, AL 35294 0022, USA
    AIDS 26:1571-3. 2012
  7. pmc The impact of highly active antiretroviral therapy on prevalence and incidence of cervical human papillomavirus infections in HIV-positive adolescents
    Sadeep Shrestha
    Department of Epidemiology, School of Public Health, University of Alabama at Birmingham, Birmingham, Alabama, USA
    BMC Infect Dis 10:295. 2010
  8. pmc The influence of human leukocyte antigen class I alleles and their population frequencies on human immunodeficiency virus type 1 control among African Americans
    Aleksandr Lazaryan
    University of Alabama at Birmingham, Birmingham, AL 35294 0022, USA
    Hum Immunol 72:312-8. 2011
  9. ncbi request reprint FcγR gene copy number in Kawasaki disease and intravenous immunoglobulin treatment response
    Robert Makowsky
    Department of Biostatistics, Division of Clinical Immunology and Rheumatology, University of Alabama at Birmingham, Birmingham, Alabama, USA
    Pharmacogenet Genomics 23:455-62. 2013
  10. pmc Interleukin-10 (IL-10) pathway: genetic variants and outcomes of HIV-1 infection in African American adolescents
    Sadeep Shrestha
    Department of Epidemiology, University of Alabama at Birmingham, Birmingham, Alabama, United States of America
    PLoS ONE 5:e13384. 2010

Detail Information

Publications32

  1. pmc Genomic copy number variants: evidence for association with antibody response to anthrax vaccine adsorbed
    Michael I Falola
    Department of Epidemiology, University of Alabama at Birmingham, Birmingham, Alabama, United States of America
    PLoS ONE 8:e64813. 2013
    ..We have tested this hypothesis in two study populations from a clinical trial of anthrax vaccination...
  2. pmc The utility of mitochondrial and y chromosome phylogenetic data to improve correction for population stratification
    Robert Makowsky
    Department of Biostatistics, School of Public Health, University of Alabama at Birmingham Birmingham, AL, USA
    Front Genet 3:301. 2012
    ....
  3. pmc RYR3 gene polymorphisms and cardiovascular disease outcomes in the context of antihypertensive treatment
    A I Lynch
    Department of Epidemiology, University of Alabama at Birmingham, Birmingham, AL 35294, USA
    Pharmacogenomics J 13:330-4. 2013
    ....
  4. pmc Short communication: lack of occult HIV infection among non-AIDS-defining cancer patients in three academic oncology clinics in the United States
    Sadeep Shrestha
    Department of Epidemiology, University of Alabama at Birmingham, Birmingham, AL 35294 0022, USA
    AIDS Res Hum Retroviruses 29:887-91. 2013
    ....
  5. doi request reprint Influence of host genetic and ecological factors in complex concomitant infections - relevance to sexually transmitted infections
    Sadeep Shrestha
    Department of Epidemiology, University of Alabama at Birmingham, Birmingham, AL 35294 0022, USA
    J Reprod Immunol 92:27-32. 2011
    ....
  6. pmc Replication of RYR3 gene polymorphism association with cIMT among HIV-infected whites
    Sadeep Shrestha
    Department of Epidemiology, University of Alabama at Birmingham, Birmingham, AL 35294 0022, USA
    AIDS 26:1571-3. 2012
    ..SNP rs2229116 was associated with common cIMT in HIV infected white men after adjusting for age and use of stavudine (d4T). The association was more evident at younger ages and decreased among older individuals...
  7. pmc The impact of highly active antiretroviral therapy on prevalence and incidence of cervical human papillomavirus infections in HIV-positive adolescents
    Sadeep Shrestha
    Department of Epidemiology, School of Public Health, University of Alabama at Birmingham, Birmingham, Alabama, USA
    BMC Infect Dis 10:295. 2010
    ..However, the impact of HAART on cervical human papillomavirus (HPV) infection, clearance, and persistence in high-risk adolescents remains controversial...
  8. pmc The influence of human leukocyte antigen class I alleles and their population frequencies on human immunodeficiency virus type 1 control among African Americans
    Aleksandr Lazaryan
    University of Alabama at Birmingham, Birmingham, AL 35294 0022, USA
    Hum Immunol 72:312-8. 2011
    ..Certain HLA class I associations with control of HIV-1 infection cross the boundaries of race and viral subtype, whereas others appear confined within one or the other of those boundaries...
  9. ncbi request reprint FcγR gene copy number in Kawasaki disease and intravenous immunoglobulin treatment response
    Robert Makowsky
    Department of Biostatistics, Division of Clinical Immunology and Rheumatology, University of Alabama at Birmingham, Birmingham, Alabama, USA
    Pharmacogenet Genomics 23:455-62. 2013
    ..However, it is not known whether the existing gene copy number (GCN) variability relates to KD treatment response, susceptibility, or associated sequelae...
  10. pmc Interleukin-10 (IL-10) pathway: genetic variants and outcomes of HIV-1 infection in African American adolescents
    Sadeep Shrestha
    Department of Epidemiology, University of Alabama at Birmingham, Birmingham, Alabama, United States of America
    PLoS ONE 5:e13384. 2010
    ....
  11. pmc Host genetics and HIV-1 viral load set-point in African-Americans
    Sadeep Shrestha
    Department of Epidemiology, School of Public Health, University of Alabama at Birmingham, Birmingham, Alabama 35294 0022, USA
    AIDS 23:673-7. 2009
    ..We attempted to confirm this finding in African-Americans and to address whether these SNPs are in linkage disequilibrium with human leukocyte antigen (HLA) class I alleles that mediate innate and adaptive immunity...
  12. pmc Clear and independent associations of several HLA-DRB1 alleles with differential antibody responses to hepatitis B vaccination in youth
    Yufeng Li
    Department of Medicine, University of Alabama at Birmingham, Birmingham, AL 35294, USA
    Hum Genet 126:685-96. 2009
    ....
  13. pmc Incidence, prevalence, and epidemiology of herpes simplex virus-2 in HIV-1-positive and HIV-1-negative adolescents
    Staci L Sudenga
    Department of Epidemiology, School of Public Health, University of Alabama at Birmingham, Birmingham, Alabama 35294 0022, USA
    Sex Transm Dis 39:300-5. 2012
    ..The objective of this study was to determine HSV-2 prevalence and incidence and associated risk factors in a HIV-1-positive and at risk HIV-1-negative adolescent population...
  14. pmc Association of chemokine receptor gene (CCR2-CCR5) haplotypes with acquisition and control of HIV-1 infection in Zambians
    Rakhi Malhotra
    Department of Epidemiology, University of Alabama at Birmingham UAB, Birmingham, AL, USA
    Retrovirology 8:22. 2011
    ....
  15. pmc Human leukocyte antigen class I supertypes and HIV-1 control in African Americans
    Aleksandr Lazaryan
    University of Alabama at Birmingham, Birmingham, Alabama 35294 0022, USA
    J Virol 84:2610-7. 2010
    ..The study demonstrated the dominant role of HLA-B supertypes in HIV-1 clade B-infected African Americans and further dissected the contributions of individual class I alleles and their population frequencies to the supertype effects...
  16. pmc Toll-like receptor gene variants associated with bacterial vaginosis among HIV-1 infected adolescents
    Kathryn E Royse
    Department of Epidemiology, School of Public Health, University of Alabama at Birmingham, Birmingham, AL 35294 0022, USA
    J Reprod Immunol 96:84-9. 2012
    ..86, 95% CI 1.17-2.95). Further studies are warranted to confirm the associations of TLR gene variants and also to understand the underlying pathways and immunogenetic correlates in the context of HIV-1 infection...
  17. pmc A candidate gene approach for virally induced cancer with application to HIV-related Kaposi's sarcoma
    Brahim Aissani
    Department of Epidemiology, University of Alabama, Birmingham, AL
    Int J Cancer 134:397-404. 2014
    ..This "proof of concept" study identified human homologs involved in the regulation of type I interferon-induced signaling, cell cycle and apoptosis potentially as important determinants of HIV-KS...
  18. pmc Role of activating FcγR gene polymorphisms in Kawasaki disease susceptibility and intravenous immunoglobulin response
    Sadeep Shrestha
    Department of Epidemiology, University of Alabama at Birmingham, USA
    Circ Cardiovasc Genet 5:309-16. 2012
    ..We tested the hypothesis that the polymorphisms in the activating receptors (FcγRIIA, FcγRIIIA, and FcγRIIIB) also influence susceptibility, IVIG treatment response, and coronary artery disease in patients with KD...
  19. pmc Genes linked to energy metabolism and immunoregulatory mechanisms are associated with subcutaneous adipose tissue distribution in HIV-infected men
    Marguerite Ryan Irvin
    Department of Epidemiology, University of Alabama at Birmingham, Alabama, USA
    Pharmacogenet Genomics 21:798-807. 2011
    ..Genetic studies may help explain abnormalities of fat distribution in HIV-infected patients treated with antiretroviral therapy (ARV)...
  20. pmc The major histocompatibility complex conserved extended haplotype 8.1 in AIDS-related non-Hodgkin lymphoma
    Brahim Aissani
    Department of Epidemiology, University of Alabama at Birmingham, Birmingham, AL 35294 0022, USA
    J Acquir Immune Defic Syndr 52:170-9. 2009
    ..Which gene variant on this highly conserved extended haplotype (CEH 8.1) in whites most likely represents a true etiologic factor remains uncertain...
  21. ncbi request reprint Interleukin-10 gene (IL10) polymorphisms and human papillomavirus clearance among immunosuppressed adolescents
    Sadeep Shrestha
    Department of Epidemiology, University of Alabama at Birmingham, 1665 University Boulevard, RPHB Room 220A, Birmingham, AL 35294 0022, USA
    Cancer Epidemiol Biomarkers Prev 16:1626-32. 2007
    ....
  22. doi request reprint Association test of multiallelic gene copy numbers in family trios
    Sadeep Shrestha
    Department of Epidemiology, School of Public Health, University of Alabama at Birmingham, Birmingham, Alabama, USA
    Genet Epidemiol 34:2-6. 2010
    ..We present theoretical derivation of the statistics and results of simulation studies that show robustness of our approach and power under several genetic models...
  23. pmc A genome-wide association study of carotid atherosclerosis in HIV-infected men
    Sadeep Shrestha
    Department of Epidemiology, School of Public Health, University of Alabama at Birmingham, 1665 University Blvd, Birmingham, AL 35294 0022, USA
    AIDS 24:583-92. 2010
    ..The role of host genetics in the development of subclinical atherosclerosis in the context of HIV-infected persons who are being treated with highly active antiretroviral therapy (HAART) is not well understood...
  24. pmc Variants in interleukin family of cytokines genes influence clearance of high risk HPV in HIV-1 coinfected African-American adolescents
    Staci L Sudenga
    Department of Epidemiology, School of Public Health, University of Alabama at Birmingham, Birmingham, AL, United States
    Hum Immunol 74:1696-700. 2013
    ..These data suggest that the analyzed genetic variants in interleukin family of cytokines modulate HR-HPV clearance in HIV-1 seropositive African-Americans that warrants replication...
  25. pmc Prevalence of proteinuria and elevated serum cystatin C among HIV-Infected Adolescents in the Reaching for Excellence in Adolescent Care and Health (REACH) study
    Kristal J Aaron
    Nephrology Research and Training Center, Division of Nephrology, Department of Medicine, University of Alabama at Birmingham, Birmingham, AL 35294 0022, USA
    J Acquir Immune Defic Syndr 61:499-506. 2012
    ..Proteinuria and elevated serum cystatin C (eCysC) are used as markers of kidney disease in the general population; however, the prevalence of these markers in HIV-infected adolescents is largely unknown...
  26. pmc Dense Genotyping of Immune-Related Loci Identifies Variants Associated with Clearance of HPV among HIV-Positive Women in the HIV Epidemiology Research Study (HERS)
    Staci L Sudenga
    Department of Epidemiology, University of Alabama at Birmingham, Birmingham, Alabama, United States of America
    PLoS ONE 9:e99109. 2014
    ..Results from this study support associations of immune-related genes, having potential biological mechanism, with differential cervical HR-HPV infection outcomes. ..
  27. pmc Assessment of high-risk human papillomavirus infections using clinician- and self-collected cervical sampling methods in rural women from far Western Nepal
    Derek C Johnson
    Department of Epidemiology, University of Alabama at Birmingham, Birmingham, Alabama, United States of America
    PLoS ONE 9:e101255. 2014
    ..We aimed to assess the distribution of HR- HPV among rural Nepali women while assessing self-collected and clinician-collected cervico-vaginal specimens as sample collection methods for HPV screening...
  28. pmc RYR3 gene variants in subclinical atherosclerosis among HIV-infected women in the Women's Interagency HIV Study (WIHS)
    Aditi Shendre
    Department of Epidemiology, University of Alabama at Birmingham, Birmingham, AL, United States
    Atherosclerosis 233:666-72. 2014
    ..We evaluated SNPs in the RYR3 gene among HIV-infected women participating in Women's Interagency HIV Study (WIHS)...
  29. pmc Natural selection among Eurasians at genomic regions associated with HIV-1 control
    Yann C Klimentidis
    Section on Statistical Genetics, Department of Biostatistics, University of Alabama at Birmingham, Birmingham, AL 35294, USA
    BMC Evol Biol 11:173. 2011
    ....
  30. pmc Variations in CCL3L gene cluster sequence and non-specific gene copy numbers
    Sadeep Shrestha
    Department of Epidemiology, University of Alabama at Birmingham, School of Public Health, 1665 University Blvd, RPHB Room 217L, Birmingham, Alabama 35294 0022, USA
    BMC Res Notes 3:74. 2010
    ..These genes are involved in host defense and inflammatory processes. Several CNV assays have been developed for the CCL3L1 gene...
  31. doi request reprint A qualitative study on factors impacting HIV care adherence among postpartum HIV-infected women in the rural southeastern USA
    Amelia K Boehme
    a Department of Epidemiology, School of Public Health, University of Alabama at Birmingham, Birmingham, AL, USA
    AIDS Care 26:574-81. 2014
    ..Intervention studies need to be cognizant of the specific needs of HIV-infected postpartum women to improve long-term clinical outcomes among this population, who have children. ..