M G Shlipak

Summary

Affiliation: University of California
Country: USA

Publications

  1. ncbi request reprint Estrogen and progestin, lipoprotein(a), and the risk of recurrent coronary heart disease events after menopause
    M G Shlipak
    Department of Medicine, University of California, and Veterans Affairs Medical Center, San Francisco, USA
    JAMA 283:1845-52. 2000
  2. ncbi request reprint Cystatin-C and mortality in elderly persons with heart failure
    Michael G Shlipak
    General Internal Medicine Section, Veterans Affairs Medical Center, 4150 Clement Street, University of California San Francisco, San Francisco, CA 94121, USA
    J Am Coll Cardiol 45:268-71. 2005
  3. ncbi request reprint Pharmacotherapy for heart failure in patients with renal insufficiency
    Michael G Shlipak
    Veterans Affairs Medical Center and University of California, San Francisco, San Francisco, California 94121, USA
    Ann Intern Med 138:917-24. 2003
  4. ncbi request reprint Lipid changes on hormone therapy and coronary heart disease events in the Heart and Estrogen/progestin Replacement Study (HERS)
    Michael G Shlipak
    General Internal Medicine Section, Veterans Affairs Medical Center, San Francisco, Calif 94121, USA
    Am Heart J 146:870-5. 2003
  5. ncbi request reprint Creatinine levels and cardiovascular events in women with heart disease: do small changes matter?
    Michael G Shlipak
    General Internal Medicine Section, Veterans Affairs Medical Center, San Francisco, CA 94121, USA
    Am J Kidney Dis 43:37-44. 2004
  6. ncbi request reprint Chronic renal insufficiency and cardiovascular events in the elderly: findings from the Cardiovascular Health Study
    Michael G Shlipak
    General Internal Medicine Section, Medical Service, Veterans Affairs Medical Center, San Francisco, CA 94121, USA
    Am J Geriatr Cardiol 13:81-90. 2004
  7. ncbi request reprint The presence of frailty in elderly persons with chronic renal insufficiency
    Michael G Shlipak
    Epidemiology and Biostatistics, University of California, San Francisco, General Internal Medicine Section, Medical Service, San Francisco Veterans Affairs Medical Center San Francisco, CA 94121, USA
    Am J Kidney Dis 43:861-7. 2004
  8. ncbi request reprint Update on cystatin C: new insights into the importance of mild kidney dysfunction
    Michael G Shlipak
    Department of Medicine, University of California, San Francisco, California 94121, USA
    Curr Opin Nephrol Hypertens 15:270-5. 2006
  9. ncbi request reprint Renal function, digoxin therapy, and heart failure outcomes: evidence from the digoxin intervention group trial
    Michael G Shlipak
    General Internal Medicine Section, San Francisco Veterans Affairs Medical Center, San Francisco, CA 94121, USA
    J Am Soc Nephrol 15:2195-203. 2004
  10. ncbi request reprint Cystatin-C and inflammatory markers in the ambulatory elderly
    Michael G Shlipak
    General Internal Medicine Section, San Francisco Veterans Affairs Medical Center and Department of Medicine, University of California, San Francisco, Calif 94121, USA
    Am J Med 118:1416. 2005

Detail Information

Publications122 found, 100 shown here

  1. ncbi request reprint Estrogen and progestin, lipoprotein(a), and the risk of recurrent coronary heart disease events after menopause
    M G Shlipak
    Department of Medicine, University of California, and Veterans Affairs Medical Center, San Francisco, USA
    JAMA 283:1845-52. 2000
    ..However, few data exist on the clinical importance of Lp(a) lowering for CHD prevention. Hormone therapy with estrogen has been found to lower Lp(a) levels in women...
  2. ncbi request reprint Cystatin-C and mortality in elderly persons with heart failure
    Michael G Shlipak
    General Internal Medicine Section, Veterans Affairs Medical Center, 4150 Clement Street, University of California San Francisco, San Francisco, CA 94121, USA
    J Am Coll Cardiol 45:268-71. 2005
    ..We sought to evaluate cystatin-C, a novel measure of renal function, as a predictor of mortality in elderly persons with heart failure (HF) and to compare it with creatinine...
  3. ncbi request reprint Pharmacotherapy for heart failure in patients with renal insufficiency
    Michael G Shlipak
    Veterans Affairs Medical Center and University of California, San Francisco, San Francisco, California 94121, USA
    Ann Intern Med 138:917-24. 2003
    ..Future clinical trials in heart failure should include a representative number of patients with renal insufficiency to improve the evidence base and outcomes in this vulnerable population...
  4. ncbi request reprint Lipid changes on hormone therapy and coronary heart disease events in the Heart and Estrogen/progestin Replacement Study (HERS)
    Michael G Shlipak
    General Internal Medicine Section, Veterans Affairs Medical Center, San Francisco, Calif 94121, USA
    Am Heart J 146:870-5. 2003
    ..To explore possible mechanisms, we examined the association between lipid changes and CHD outcomes among women assigned to hormone therapy...
  5. ncbi request reprint Creatinine levels and cardiovascular events in women with heart disease: do small changes matter?
    Michael G Shlipak
    General Internal Medicine Section, Veterans Affairs Medical Center, San Francisco, CA 94121, USA
    Am J Kidney Dis 43:37-44. 2004
    ....
  6. ncbi request reprint Chronic renal insufficiency and cardiovascular events in the elderly: findings from the Cardiovascular Health Study
    Michael G Shlipak
    General Internal Medicine Section, Medical Service, Veterans Affairs Medical Center, San Francisco, CA 94121, USA
    Am J Geriatr Cardiol 13:81-90. 2004
    ..The identification of CRI in the elderly and the use of cardiovascular prevention therapies represent a major opportunity to reduce their burden of cardiovascular morbidity...
  7. ncbi request reprint The presence of frailty in elderly persons with chronic renal insufficiency
    Michael G Shlipak
    Epidemiology and Biostatistics, University of California, San Francisco, General Internal Medicine Section, Medical Service, San Francisco Veterans Affairs Medical Center San Francisco, CA 94121, USA
    Am J Kidney Dis 43:861-7. 2004
    ..We hypothesized that chronic renal insufficiency (CRI) would be associated with a greater prevalence of frailty and disability in the elderly...
  8. ncbi request reprint Update on cystatin C: new insights into the importance of mild kidney dysfunction
    Michael G Shlipak
    Department of Medicine, University of California, San Francisco, California 94121, USA
    Curr Opin Nephrol Hypertens 15:270-5. 2006
    ..Studies have questioned, however, whether cystatin C is predominantly a measure of kidney function. This review summarizes the research literature on cystatin C...
  9. ncbi request reprint Renal function, digoxin therapy, and heart failure outcomes: evidence from the digoxin intervention group trial
    Michael G Shlipak
    General Internal Medicine Section, San Francisco Veterans Affairs Medical Center, San Francisco, CA 94121, USA
    J Am Soc Nephrol 15:2195-203. 2004
    ..Renal dysfunction is strongly associated with mortality in stable outpatients with heart failure, notably in patients with estimated GFR <50 ml/min per 1.73 m(2). The effect of digoxin did not differ by level of renal function...
  10. ncbi request reprint Cystatin-C and inflammatory markers in the ambulatory elderly
    Michael G Shlipak
    General Internal Medicine Section, San Francisco Veterans Affairs Medical Center and Department of Medicine, University of California, San Francisco, Calif 94121, USA
    Am J Med 118:1416. 2005
    ..We compared cystatin-C, a novel marker of renal function, with creatinine and estimated glomerular filtration rate (eGFR) as predictors of C-reactive protein and fibrinogen levels...
  11. ncbi request reprint Cystatin C and the risk of death and cardiovascular events among elderly persons
    Michael G Shlipak
    General Internal Medicine Section, Veterans Affairs Medical Center, University of California, San Francisco, USA
    N Engl J Med 352:2049-60. 2005
    ..We compared creatinine and cystatin C levels as predictors of mortality from cardiovascular causes and from all causes in the Cardiovascular Health Study, a cohort study of elderly persons living in the community...
  12. ncbi request reprint Cardiovascular mortality risk in chronic kidney disease: comparison of traditional and novel risk factors
    Michael G Shlipak
    General Internal Medicine Section, Veterans Affairs Medical Center, and Department of Medicine, University of California, San Francisco 94121, USA
    JAMA 293:1737-45. 2005
    ..Elderly persons with chronic kidney disease have substantial risk for cardiovascular mortality, but the relative importance of traditional and novel risk factors is unknown...
  13. ncbi request reprint Elevations of inflammatory and procoagulant biomarkers in elderly persons with renal insufficiency
    Michael G Shlipak
    Department of Medicine, University of California, San Francisco, and the Veterans Affairs Medical Center, San Francisco 94121, USA
    Circulation 107:87-92. 2003
    ..Little is known about the association of renal insufficiency with inflammatory and procoagulant markers, which are potential mediators for the cardiovascular risk of kidney disease...
  14. ncbi request reprint Association of renal insufficiency with treatment and outcomes after myocardial infarction in elderly patients
    Michael G Shlipak
    General Internal Medicine Section, Veterans Affairs Medical Center 111A1 and University of California, San Francisco, 4150 Clement Street, San Francisco, CA 94121, USA
    Ann Intern Med 137:555-62. 2002
    ..Patients with end-stage renal disease are known to have decreased survival after myocardial infarction, but the association of less severe renal dysfunction with survival after myocardial infarction is unknown...
  15. ncbi request reprint Renal insufficiency and cardiovascular events in postmenopausal women with coronary heart disease
    M G Shlipak
    General Internal Medicine Section, Veterans Affairs Medical Center, San Francisco, California 94121, USA
    J Am Coll Cardiol 38:705-11. 2001
    ..This study sought to determine the independent association of renal insufficiency with cardiovascular risk among women with known coronary heart disease (CHD)...
  16. ncbi request reprint Clinical symptoms and myocardial infarction in left bundle branch block patients
    M G Shlipak
    General Internal Medicine Section, Veterans Affairs Medical Center, and Department of Medicine, University of California, San Francisco, CA 94121, USA
    Cardiology 93:100-4. 2000
    ..The clinical history was not effective at distinguishing LBBB patients with myocardial infarction among patients who appeared to be candidates for acute reperfusion therapy...
  17. ncbi request reprint Treatment and outcomes of left bundle-branch block patients with myocardial infarction who present without chest pain. National Registry of Myocardial Infarction 2 Investigators
    M G Shlipak
    General Internal Medicine Section, San Francisco VA Medical Center, California 94121, USA
    J Am Coll Cardiol 36:706-12. 2000
    ..We sought to determine the importance of chest pain on presentation as a predictor of in-hospital treatment and mortality in myocardial infarction (MI) patients with left bundle-branch block (LBBB)...
  18. ncbi request reprint The incidence of unrecognized myocardial infarction in women with coronary heart disease
    M G Shlipak
    General Internal Medicine Section 111A 1, Veterans Affairs Medical Center, 4150 Clement Street, San Francisco, CA 94121, USA
    Ann Intern Med 134:1043-7. 2001
    ..Several cohort studies in populations without coronary heart disease have demonstrated that up to 40% of incident myocardial infarctions are clinically unrecognized...
  19. ncbi request reprint Cardiovascular disease risk status in elderly persons with renal insufficiency
    Michael G Shlipak
    General Internal Medicine Section, Medical Service, Veterans Affairs Medical Center 111A1, 4150 Clement Street, San Francisco, CA 94121, USA
    Kidney Int 62:997-1004. 2002
    ..We determined the prevalence of elevated cardiovascular disease risk status among elderly persons with renal insufficiency...
  20. ncbi request reprint Hormone therapy and the risk of stroke after acute myocardial infarction in postmenopausal women
    B G Angeja
    Department of Medicine, University of California, San Francisco, California 94143, USA
    J Am Coll Cardiol 38:1297-301. 2001
    ..We examined the association of hormone therapy (HRT) with hemorrhagic and ischemic stroke among postmenopausal women with acute myocardial infarction (AMI)...
  21. pmc Incidence and progression of coronary calcification in chronic kidney disease: the Multi-Ethnic Study of Atherosclerosis
    Bryan R Kestenbaum
    Division of Nephrology, Department of Medicine, Harborview Medical Center, Kidney Research Institute, University of Washington, Seattle, Washington 98104 2499, USA
    Kidney Int 76:991-8. 2009
    ..Our study shows that coronary artery calcification is common in people with stage 3 disease, progresses rapidly, and may contribute to cardiovascular risk...
  22. ncbi request reprint Hormone therapy and in-hospital survival after myocardial infarction in postmenopausal women
    M G Shlipak
    General Internal Medicine Section, Veterans Affairs Medical Center, Department of Medicine, University of California, San Francisco, USA
    Circulation 104:2300-4. 2001
    ..CONCLUSIONS: Postmenopausal HRT appears to be associated with reduced mortality after myocardial infarction. This finding could be caused by therapeutic effect of HRT, selection and adherence bias, or some combination of both...
  23. pmc Serum creatinine and functional limitation in elderly persons
    Michelle C Odden
    Department of Epidemiology, School of Public Health, University of California, Berkeley, USA
    J Gerontol A Biol Sci Med Sci 64:370-6. 2009
    ..We hypothesized that higher serum creatinine would be associated with self-reported functional limitation in community-dwelling elderly...
  24. pmc Relation of kidney function and albuminuria with atrial fibrillation (from the Heart and Soul Study)
    David D McManus
    Section of Cardiac Electrophysiology, Division of Cardiology, Department of Medicine, University of Massachusetts, Worcester, Massachusetts, USA
    Am J Cardiol 104:1551-5. 2009
    ..36, 95% CI 1.45 to 13.05) or eGFR(Cr) (OR 4.61, 95% CI 1.56 to 13.66). In conclusion, among outpatients with coronary artery disease, lower eGFR(cys) and higher ACR were associated with prevalent AF, independent of each other...
  25. pmc Association of cystatin C and estimated GFR with inflammatory biomarkers: the Heart and Soul Study
    David Singh
    Department of Medicine, University of California, San Francisco, CA 94121, USA
    Nephrol Dial Transplant 22:1087-92. 2007
    ..In this study, we compared the relative strengths of association of cystatin C and estimated glomerular filtration rate (eGFR) with inflammatory biomarkers...
  26. ncbi request reprint Impact of renal insufficiency on mortality in advanced lower extremity peripheral arterial disease
    ANN M O'HARE
    Division of Nephrology, Box 111J, Nephrology, VA Medical Center San Francisco, 4150 Clement Street, San Francisco, CA 94121, USA
    J Am Soc Nephrol 16:514-9. 2005
    ..Death rates were particularly high among those with a GFR <30 ml/min per 1.73 m(2). This finding may be partly explained by their more frequent presentation with ischemic ulceration or gangrene rather than rest pain...
  27. pmc Inflammatory biomarkers and decline in kidney function in the elderly: the Cardiovascular Health Study
    Christopher Keller
    Department of Medicine, University of California San Francisco, San Francisco, CA, USA
    Nephrol Dial Transplant 25:119-24. 2010
    ..The objective of this study was to determine whether elevated markers of inflammation are independently associated with longitudinal kidney function decline...
  28. ncbi request reprint Kidney function and markers of inflammation in elderly persons without chronic kidney disease: the health, aging, and body composition study
    C R Keller
    Department of Medicine, University of California, San Francisco, California, USA
    Kidney Int 71:239-44. 2007
    ..05). Cystatin C has a linear association with inflammatory biomarkers in an ambulatory elderly cohort with estimated glomerular filtration rates >or=60; associations are particularly strong with TNF-alpha and the STNF-R...
  29. pmc Cystatin C concentration as a predictor of systolic and diastolic heart failure
    Andrew Moran
    Department of Medicine, University of California at San Francisco, San Francisco, California, USA
    J Card Fail 14:19-26. 2008
    ..We hypothesized that kidney dysfunction would predict diastolic HF (DHF) better than systolic HF (SHF) in the Cardiovascular Health Study...
  30. pmc C-reactive protein and ischemia in users and nonusers of beta-blockers and statins: data from the Heart and Soul Study
    Mary S Beattie
    Department of Medicine, University of California, San Francisco, USA
    Circulation 107:245-50. 2003
    ..Elevated levels of C-reactive protein (CRP) are associated with an increased risk of coronary events, but whether inflammation is associated with inducible ischemia in patients with stable coronary disease is unknown...
  31. ncbi request reprint Cystatin C and mortality risk in the elderly: the health, aging, and body composition study
    Michael G Shlipak
    University of San Francisco, General Internal Medicine Section, VA Medical Center 111A1, 4150 Clement Street, San Francisco, CA 94121, USA
    J Am Soc Nephrol 17:254-61. 2006
    ..39], 0.95 [0.68 to 1.32], 1.11 [0.79 to 1.57], 1.16 [0.86 to 1.58]). Cystatin C is a strong, independent risk factor for mortality in the elderly. Future studies should investigate whether cystatin C has a role in clinical medicine...
  32. pmc Cystatin C, albuminuria, and 5-year all-cause mortality in HIV-infected persons
    ANDY CHOI
    University of California, San Francisco, CA, USA
    Am J Kidney Dis 56:872-82. 2010
    ..However, the clinical importance of increased cystatin C level and albuminuria in the HIV-infected population has not been studied...
  33. pmc Fibroblast growth factor-23 and early decrements in kidney function: the Heart and Soul Study
    Joachim H Ix
    Division of Nephrology, Department of Medicine, University of California San Diego, San Diego, CA, USA
    Nephrol Dial Transplant 25:993-7. 2010
    ..The threshold of CKD or albuminuria at which FGF-23 begins to change is unknown...
  34. pmc Microalbuminuria in HIV infection
    Lynda Anne Szczech
    Duke University Medical Center, Department of Medicine, Division of Nephrology, Durham, North Carolina, USA
    AIDS 21:1003-9. 2007
    ..Microalbuminuria is associated with increased risk of cardiovascular disease and mortality. The objective of the study was to evaluate if HIV infection was an independent risk factor for microalbuminuria...
  35. ncbi request reprint Risk factors and secondary prevention in women with heart disease: the Heart and Estrogen/progestin Replacement Study
    Eric Vittinghoff
    University of California, San Francisco and Veterans Affairs Medical Center, San Francisco, 74 New Montgomery, Suite 600, San Francisco, California 94105, USA
    Ann Intern Med 138:81-9. 2003
    ..Risk factors for coronary heart disease events have most commonly been evaluated in healthy men...
  36. pmc Cystatin C and carotid intima-media thickness in asymptomatic adults: the Multi-Ethnic Study of Atherosclerosis (MESA)
    Anh L Bui
    Department of Medicine, University of California, San Francisco, CA, USA
    Am J Kidney Dis 53:389-98. 2009
    ..We therefore explored whether serum cystatin C level is associated with carotid intima-media thickness (IMT) in ambulatory adults without clinical heart disease...
  37. ncbi request reprint Comparison of the effects of angiotensin converting-enzyme inhibitors and beta blockers on survival in elderly patients with reduced left ventricular function after myocardial infarction
    M G Shlipak
    Medical Service, Veterans Affairs Medical Center, University of California, San Francisco 94121, USA
    Am J Med 110:425-33. 2001
    ..Our results suggest that patients who can tolerate both medications gain additional benefit from the combination...
  38. ncbi request reprint Differences in medical care and disease outcomes among black and white women with heart disease
    Ashish K Jha
    Division of General Medicine, San Francisco VA Medical Center, San Francisco, USA
    Circulation 108:1089-94. 2003
    ..We sought to evaluate differences in medical care and clinical outcomes among black and white women with established coronary artery disease...
  39. pmc Left ventricular hypertrophy in mild and moderate reduction in kidney function determined using cardiac magnetic resonance imaging and cystatin C: the multi-ethnic study of atherosclerosis (MESA)
    Andrew Moran
    Division of General Internal Medicine, Department of Medicine, Columbia University, New York, NY, USA
    Am J Kidney Dis 52:839-48. 2008
    ..We hypothesized that mild and moderate decreases in kidney function, reflected in greater serum cystatin C concentrations, would be linearly associated with a greater prevalence of LVH...
  40. pmc Association of chronic kidney disease with the spectrum of ankle brachial index the CHS (Cardiovascular Health Study)
    Joachim H Ix
    Department of Medicine, University of California San Diego, USA
    J Am Coll Cardiol 54:1176-84. 2009
    ..This study sought to determine the association of chronic kidney disease (CKD) with high ankle brachial index (ABI) measurement and to compare its strength with that of CKD with a low ABI...
  41. ncbi request reprint Relationship between hepatitis C and chronic kidney disease: results from the Third National Health and Nutrition Examination Survey
    Judith I Tsui
    General Internal Medicine, Section 111A1, VA Medical Center, 4150 Clement Street, San Francisco, CA 94124, USA
    J Am Soc Nephrol 17:1168-74. 2006
    ....
  42. ncbi request reprint Cystatin C and incident peripheral arterial disease events in the elderly: results from the Cardiovascular Health Study
    ANN M O'HARE
    Nephrology Division, Department of Medicine, and General Internal Medicine Section, Veterans Affairs Medical Center San Francisco, 4150 Clement Street, San Faancisco, CA 94121, USA
    Arch Intern Med 165:2666-70. 2005
    ..The association of cystatin C, a novel marker of renal function, with risk for developing complications related to peripheral arterial disease (PAD) has not been examined...
  43. ncbi request reprint Association of chronic kidney disease with clinical outcomes after coronary revascularization: the Arterial Revascularization Therapies Study (ARTS)
    Joachim H Ix
    Department of Medicine, University of California, San Francisco, Calif, USA
    Am Heart J 149:512-9. 2005
    ..In the Arterial Revascularization Therapies Study (ARTS), we compared long-term clinical outcomes after CABG or PCI with multivessel stenting in patients with CKD...
  44. pmc Cystatin C level as a marker of kidney function in human immunodeficiency virus infection: the FRAM study
    Michelle C Odden
    Department of Medicine, San FranciscoVeterans Affairs Medical Center 4150 Clement Street, San Francisco, CA 94121, USA
    Arch Intern Med 167:2213-9. 2007
    ..Cystatin C measurement may be more sensitive than creatinine for detecting impaired kidney function in persons with HIV...
  45. pmc Simple anthropometric measures correlate with metabolic risk indicators as strongly as magnetic resonance imaging-measured adipose tissue depots in both HIV-infected and control subjects
    Rebecca Scherzer
    Northern California Institute for Research and Education, San Francisco, CA, USA
    Am J Clin Nutr 87:1809-17. 2008
    ..Studies in persons without HIV infection have compared percentage body fat (%BF) and waist circumference as markers of risk for the complications of excess adiposity, but only limited study has been conducted in HIV-infected subjects...
  46. ncbi request reprint Racial differences in mortality among men hospitalized in the Veterans Affairs health care system
    A K Jha
    General Internal Medicine Section 111A1, Veterans Affairs Medical Center, 4150 Clement St, San Francisco, CA 94121, USA
    JAMA 285:297-303. 2001
    ..Few studies have examined racial differences in health outcomes in such a system...
  47. pmc Urinary creatinine excretion rate and mortality in persons with coronary artery disease: the Heart and Soul Study
    Joachim H Ix
    Division of Nephrology and Hypertension, Department of Medicine, University of California San Diego, and VA San Diego Healthcare System, 3350 La Jolla Village Dr, Mail Code 111 H, San Diego, CA 92161, USA
    Circulation 121:1295-303. 2010
    ..In persons with coronary artery disease, low body mass index is associated with greater mortality; however, it is uncertain whether low muscle mass is a risk factor for mortality in this setting...
  48. pmc Association of anemia with diastolic dysfunction among patients with coronary artery disease in the Heart and Soul Study
    Deepu Nair
    Department of Department of Medicine, University of California, San Francisco, California, USA
    Am J Cardiol 95:332-6. 2005
    ..6, 95% CI 0.6 to 4.6) were not significantly associated with LVH. We found anemia to be strongly associated with diastolic dysfunction but not with LVH in this community-based sample of outpatients who had established coronary disease...
  49. ncbi request reprint Relationship between homocysteine and mortality in chronic kidney disease
    Vandana Menon
    Division of Nephrology, Department of Medicine, Tufts New England Medical Center, Boston, MA, USA
    Circulation 113:1572-7. 2006
    ..The relationship between total homocysteine (tHcy) and outcomes has not been investigated in patients with chronic kidney disease stages 3 to 4...
  50. ncbi request reprint Association of antihypertensive therapy and diastolic hypotension in chronic kidney disease
    Carmen A Peralta
    General Internal Medicine Section, San Francisco Veterans Affairs Medical Center, CA 94121, USA
    Hypertension 50:474-80. 2007
    ..Given recent evidence suggesting adverse effects of diastolic hypotension, these results suggest potential risks in patients with CKD from aggressive attempts to control systolic blood pressure...
  51. pmc Fetuin-A and change in body composition in older persons
    Joachim H Ix
    Division of Nephrology, Department of Medicine, and Division of Preventive Medicine, University of California San Diego, Veterans Affairs San Diego Healthcare System, San Diego, California 92161, USA
    J Clin Endocrinol Metab 94:4492-8. 2009
    ..Whether higher fetuin-A concentrations are associated with accumulation of adiposity over time is unknown...
  52. pmc Fetuin-A and incident diabetes mellitus in older persons
    Joachim H Ix
    Division of Nephrology and Hypertension, Department of Medicine, University of California, San Diego, and San Diego Veterans Affairs Healthcare System, 3350 La Jolla Village Dr, Mail Code 111 H, San Diego, CA 92161, USA
    JAMA 300:182-8. 2008
    ..In prior cross-sectional studies in humans, higher fetuin-A levels were associated with insulin resistance. However, the longitudinal association of fetuin-A with incident type 2 diabetes mellitus is unknown...
  53. pmc Cystatin C and aging success
    Mark J Sarnak
    Department of Medicine, Tufts New England Medical Center, Boston, Massachusetts 02111, USA
    Arch Intern Med 168:147-53. 2008
    ..To our knowledge, the effect of kidney function on successful aging has not been examined...
  54. pmc HIV viremia and changes in kidney function
    Chris T Longenecker
    University of California, San Francisco, California 94121, USA
    AIDS 23:1089-96. 2009
    ..To evaluate the effect of HIV infection on longitudinal changes in kidney function and to identify independent predictors of kidney function changes in HIV-infected individuals...
  55. pmc The PRIME curriculum. Clinical research training during residency
    R J Kohlwes
    General Internal Medicine Section, Veterans Affairs Medical Center, San Francisco, CA 94121, USA
    J Gen Intern Med 21:506-9. 2006
    ..In 2000, we implemented a novel research methods curriculum with the dual purposes of teaching basic epidemiology skills and providing mentored opportunities for clinical research projects during residency...
  56. ncbi request reprint Of principles and pens: attitudes and practices of medicine housestaff toward pharmaceutical industry promotions
    M A Steinman
    VA National Quality Scholars Program, San Francisco Veterans Affairs Medical Center, California, USA
    Am J Med 110:551-7. 2001
    ..We studied these attitudes and practices among internal medicine housestaff...
  57. ncbi request reprint The relative safety of ephedra compared with other herbal products
    Stephen Bent
    Osher Center for Integrative Medicine at the University of California, San Francisco, and San Francisco Veterans Affairs Medical Center, San Francisco, 111 A1, 4150 Clement Street, San Francisco, California 94121, USA
    Ann Intern Med 138:468-71. 2003
    ..Ephedra is widely used in dietary supplements that are marketed to promote weight loss or increase energy; however, the safety of this product has been questioned because of numerous case reports of adverse events...
  58. pmc Common genetic variants associate with serum phosphorus concentration
    Bryan Kestenbaum
    Division of Nephrology, Department of Medicine, University of Washington, Kidney Research Institute, Seattle, Washington 98104 2499, USA
    J Am Soc Nephrol 21:1223-32. 2010
    ..05 for each). In conclusion, common genetic variants associate with serum phosphorus in the general population. Further study of the loci identified in this study may help elucidate mechanisms of phosphorus regulation...
  59. pmc Race differences in prevalence of chronic kidney disease among young adults using creatinine-based glomerular filtration rate-estimating equations
    Carmen A Peralta
    Department of Medicine, University of California San Francisco, San Francisco, CA, USA
    Nephrol Dial Transplant 25:3934-9. 2010
    ..Current creatinine-based glomerular filtration rate (GFR)-estimating equations may misclassify young, healthy blacks...
  60. pmc Chronic kidney disease and cognitive function in older adults: findings from the chronic renal insufficiency cohort cognitive study
    Kristine Yaffe
    Department of Psychiatry, School of Medicine, University of California at San Francisco, San Francisco, California, USA
    J Am Geriatr Soc 58:338-45. 2010
    ....
  61. pmc HIV-infected persons continue to lose kidney function despite successful antiretroviral therapy
    Andy I Choi
    Department of Medicine, San Francisco Veterans Affairs Medical Center, San Francisco, California 94121, USA
    AIDS 23:2143-9. 2009
    ..To identify risk factors associated with kidney function decline in a contemporary cohort of treated and untreated HIV-infected patients...
  62. pmc The Association of African Ancestry and elevated creatinine in the Coronary Artery Risk Development in Young Adults (CARDIA) Study
    Carmen A Peralta
    Department of Medicine, University of California San Francisco, USA
    Am J Nephrol 31:202-8. 2010
    ..05 (4.81-17.02) for black men with >80% African ancestry. Genetic factors common to African ancestry may be associated with increased risk of early kidney dysfunction in a young, healthy population, particularly among black men...
  63. pmc Association of mild to moderate kidney dysfunction and coronary calcification
    Joachim H Ix
    Division of Nephrology and Hypertension, Department of Medicine, University of California San Diego, and San Diego VA Healthcare System, 3350 La Jolla Village Drive, Mail Code 111 H, San Diego, CA 92161, USA
    J Am Soc Nephrol 19:579-85. 2008
    ..These results suggest that a higher burden of CAC is unlikely to explain the association between mild to moderate kidney dysfunction and cardiovascular mortality...
  64. pmc Rapid decline of kidney function increases cardiovascular risk in the elderly
    Michael G Shlipak
    General Internal Medicine Section, San Francisco VA Medical Center and Departments of Medicine, Epidemiology, and Biostatistics, University of California San Francisco, 4150 Clement Street, San Francisco, CA 94121, USA
    J Am Soc Nephrol 20:2625-30. 2009
    ..97 to 1.45). The association of rapid decline with each outcome did not differ by the presence or absence of CKD. In conclusion, declining kidney function associates with higher risk for HF, MI, and PAD among patients with or without CKD...
  65. pmc Kidney function and multiple hemostatic markers: cross sectional associations in the multi-ethnic study of atherosclerosis
    Ruth Dubin
    Department of Medicine, Division Nephrology, University of California San Francisco, 521 Parnassus Avenue, San Francisco, CA 94143 0532, USA
    BMC Nephrol 12:3. 2011
    ..73 m2, chronic kidney disease (CKD) is strongly and independently associated with cardiovascular and overall mortality. We hypothesized that reduced kidney function would be characterized by abnormalities of hemostasis...
  66. pmc The differential association of kidney dysfunction with small and large arterial elasticity: the multiethnic study of atherosclerosis
    Carmen A Peralta
    General Internal Medicine Section 111A1, Veterans Affairs Medical Center, San Francisco, CA 94124, USA
    Am J Epidemiol 169:740-8. 2009
    ..26, 0.48, 0.45). Early kidney dysfunction is significantly associated with decreased arterial elasticity in smaller arteries and, to a lesser degree, in larger arteries...
  67. pmc Uromodulin concentrations are not associated with incident CKD among persons with coronary artery disease
    Michael G Shlipak
    San Francisco VA Medical Center, CA, USA
    BMC Nephrol 12:2. 2011
    ..This study within persons with known coronary artery disease (CAD) evaluated whether uromodulin concentrations could distinguish CKD risk...
  68. pmc Association of cystatin C with mortality, cardiovascular events, and incident heart failure among persons with coronary heart disease: data from the Heart and Soul Study
    Joachim H Ix
    Division of Nephrology, Department of Medicine, Box 0532, HSE 672, University of California at San Francisco, San Francisco, CA 94143 0532, USA
    Circulation 115:173-9. 2007
    ..Cystatin C is a novel and sensitive endogenous marker of kidney function. Whether cystatin C concentrations are associated with adverse events among ambulatory persons with CHD is unknown...
  69. ncbi request reprint Renal function and heart failure risk in older black and white individuals: the Health, Aging, and Body Composition Study
    Kirsten Bibbins-Domingo
    Division of General Internal Medicine, San Francisco General Hospital, CA 94143 1364, USA
    Arch Intern Med 166:1396-402. 2006
    ..Our objective was to determine whether the association of chronic kidney disease with incident heart failure differs between blacks and whites...
  70. pmc Cystatin C, left ventricular hypertrophy, and diastolic dysfunction: data from the Heart and Soul Study
    Joachim H Ix
    Division of Nephrology, Department of Medicine, Box 0532, HSE 672, University of California, San Francisco, San Francisco, CA 94143 0532, USA
    J Card Fail 12:601-7. 2006
    ..We evaluate whether cystatin C is associated with left ventricular hypertrophy, diastolic dysfunction, and systolic dysfunction among 818 outpatients with coronary artery disease who were free of clinical heart failure...
  71. pmc Association between human fetuin-A and the metabolic syndrome: data from the Heart and Soul Study
    Joachim H Ix
    Division of Nephrology, Department of Medicine, University of California, San Francisco, CA 94143 0532, USA
    Circulation 113:1760-7. 2006
    ..We evaluated the association between human serum fetuin-A and the metabolic syndrome (MetS) in a cohort of persons with coronary artery disease...
  72. ncbi request reprint Mortality and cardiovascular risk across the ankle-arm index spectrum: results from the Cardiovascular Health Study
    ANN M O'HARE
    Nephrology Division, Department of Medicine, VA Medical Center San Francisco, University of California, San Francisco, CA, USA
    Circulation 113:388-93. 2006
    ..A high AAI also appears to be associated with higher mortality risk in select populations. However, mortality and cardiovascular risk across the AAI spectrum have not been described in a more broadly defined population...
  73. ncbi request reprint Predictors of heart failure among women with coronary disease
    Kirsten Bibbins-Domingo
    Division of General Internal Medicine, San Francisco General Hospital, University of California, San Francisco, San Francisco, CA 94143 1364, USA
    Circulation 110:1424-30. 2004
    ..We determined the risk factors for developing heart failure among postmenopausal women with established coronary disease...
  74. ncbi request reprint Effect of hormone therapy on mortality rates among women with heart failure and coronary artery disease
    Kirsten Bibbins-Domingo
    Division of General Internal Medicine, San Francisco General Hospital, University of California San Francisco, San Francisco, CA 94143, USA
    Am J Cardiol 95:289-91. 2005
    ..Over the 4.1-year follow-up, estrogen plus progestin use had no effect on all-cause mortality (hazard ratio 1.0, 95% confidence interval 0.7 to 1.4, p = 0.8) in women with heart failure and coronary disease...
  75. pmc Kidney function and systolic blood pressure new insights from cystatin C: data from the Heart and Soul Study
    Carmen A Peralta
    General Internal Medicine Section, San Francisco Veterans Affairs Medical Center, and Department of Medicine, University of California, San Francisco, San Francisco, California 94124, USA
    Am J Hypertens 19:939-46. 2006
    ..Whether kidney function in the normal range is associated with systolic BP (SBP), diastolic BP (DBP), and pulse pressure is unclear...
  76. pmc Risk factors for chronic kidney disease among American Indians and Alaska Natives--findings from the Kidney Early Evaluation Program
    Stacey E Jolly
    General Internal Medicine Division, University of California San Francisco, San Francisco, CA 94143, USA
    Am J Nephrol 29:440-6. 2009
    ..Less is known about chronic kidney disease (CKD) among AIAN and whether risk factors differ for low estimated glomerular filtration rate (eGFR) versus albuminuria with a normal eGFR...
  77. ncbi request reprint Cystatin C and prognosis for cardiovascular and kidney outcomes in elderly persons without chronic kidney disease
    Michael G Shlipak
    San Francisco Veterans Affairs Medical Center and University of California, San Francisco, San Francisco, California 94121, USA
    Ann Intern Med 145:237-46. 2006
    ..73 m2)...
  78. pmc Clinical and subclinical cardiovascular disease and kidney function decline in the elderly
    Michael G Shlipak
    San Francisco VA Medical Center, San Francisco, CA 94121, USA
    Atherosclerosis 204:298-303. 2009
    ..As a proxy for the renovascular system, we evaluated the association of clinical and subclinical cardiovascular disease (CVD) with kidney function decline...
  79. pmc Rate of kidney function decline in older adults: a comparison using creatinine and cystatin C
    Michael G Shlipak
    General Internal Medicine Section, San Francisco VA Medical Center, San Francisco, CA 94121, USA
    Am J Nephrol 30:171-8. 2009
    ..The aim of this study was to determine the decline in the estimated glomerular filtration rate (eGFR) in elderly persons and to compare estimates based on creatinine and cystatin C...
  80. doi request reprint Long-term clinical consequences of acute kidney injury in the HIV-infected
    Andy I Choi
    Department of Medicine, San Francisco VA Medical Center, 4150 Clement Street, San Francisco, CA 94121, USA
    Kidney Int 78:478-85. 2010
    ..Additionally, AKI affected almost one of six patients with HIV who survived at least 90 days following discharge...
  81. pmc Preclinical atherosclerosis due to HIV infection: carotid intima-medial thickness measurements from the FRAM study
    Carl Grunfeld
    Medical Service, Department of Veterans Affairs Medical Center, University of California, San Francisco, California 94121, USA
    AIDS 23:1841-9. 2009
    ..However, it is controversial whether HIV infection contributes to accelerated atherosclerosis independent of traditional CVD risk factors...
  82. pmc Fetuin-A and kidney function in persons with coronary artery disease--data from the Heart and Soul Study
    Joachim H Ix
    Division of Nephrology, Department of Medicine, Box 0532, HSE 672, University of California, San Francisco, San Francisco, CA 94143 0532, USA
    Nephrol Dial Transplant 21:2144-51. 2006
    ..Whether fetuin-A concentrations are also lower in the setting of mild-to-moderate chronic kidney disease (CKD) is unknown...
  83. ncbi request reprint The incidence of end-stage renal disease is increasing faster than the prevalence of chronic renal insufficiency
    Chi yuan Hsu
    University of California, San Francisco, San Francisco, California 94143 0532, USA
    Ann Intern Med 141:95-101. 2004
    ..The steady increase in end-stage renal disease (ESRD) incidence is a worldwide public health crisis...
  84. pmc Age and cystatin C in healthy adults: a collaborative study
    Michelle C Odden
    Department of Epidemiology, School of Public Health, University of California, Berkeley, CA, USA
    Nephrol Dial Transplant 25:463-9. 2010
    ..The effect of age on kidney function has not been well described in a healthy population across a wide age spectrum...
  85. pmc Differences in albuminuria between Hispanics and whites: an evaluation by genetic ancestry and country of origin: the multi-ethnic study of atherosclerosis
    Carmen A Peralta
    Department of Medicine, University of California San Francisco, San Francisco, CA 94121, USA
    Circ Cardiovasc Genet 3:240-7. 2010
    ..Reports show higher prevalence of albuminuria among Hispanics compared with whites. Differences by country of origin or genetic background are unknown...
  86. ncbi request reprint Clinician awareness of adherence to hypertension guidelines
    Michael A Steinman
    Division of Geriatrics, San Francisco VA Medical Center and the University of California, San Francisco 94121, USA
    Am J Med 117:747-54. 2004
    ..We compared clinicians' beliefs about their adherence to hypertension guidelines with data on their actual performance...
  87. ncbi request reprint Renal insufficiency as an independent predictor of mortality among women with heart failure
    Kirsten Bibbins-Domingo
    Division of General Internal Medicine, San Francisco General Hospital, University of California at San Francisco, San Francisco, CA 94143 1364, USA
    J Am Coll Cardiol 44:1593-600. 2004
    ..We sought to explore the association between renal insufficiency and mortality among women with heart failure (HF) and to evaluate this risk by the presence of preserved or depressed systolic function...
  88. pmc Structural and functional vascular alterations and incident hypertension in normotensive adults: the Multi-Ethnic Study of Atherosclerosis
    Carmen A Peralta
    General Internal Medicine Section 111A1, VA Medical Center, 4150 Clement Street, San Francisco, CA 94124, USA
    Am J Epidemiol 171:63-71. 2010
    ..88, 3.95; and IRR = 2.85, 95% CI: 1.95, 4.16). Structural and functional vascular abnormalities are independent predictors of incident hypertension. These findings are important for understanding the pathogenesis of hypertension...
  89. pmc Association of upper trunk and visceral adipose tissue volume with insulin resistance in control and HIV-infected subjects in the FRAM study
    Carl Grunfeld
    Department of Medicine, University of California, San Francisco, CA, USA
    J Acquir Immune Defic Syndr 46:283-90. 2007
    ..Thus, VAT and upper trunk SAT are independently associated with insulin resistance in controls and in HIV-infected persons...
  90. pmc Association between kidney function and albuminuria with cardiovascular events in HIV-infected persons
    Andy I Choi
    Department of Medicine, San Francisco Veterans Affairs Medical Center, and University of California, San Francisco, USA
    Circulation 121:651-8. 2010
    ..We examined the association between longitudinal measures of kidney function and albuminuria with risk of atherosclerotic CVD and heart failure in a contemporary cohort of HIV-infected individuals...
  91. ncbi request reprint Association of total and central obesity with mortality in postmenopausal women with coronary heart disease
    Alka M Kanaya
    Division of General Internal Medicine, Department of Medicine, University of California, San Francisco, San Francisco, CA 64115, USA
    Am J Epidemiol 158:1161-70. 2003
    ....
  92. pmc Cystatin C as a marker of cognitive function in elders: findings from the health ABC study
    Kristine Yaffe
    Department of Psychiatry, School of Medicine, University of California, San Francisco, CA 94121, USA
    Ann Neurol 63:798-802. 2008
    ..92; 95% confidence interval, 1.37-2.69; Digit Symbol Substitution: 38 vs 26%; odds ratio, 1.54; 95% confidence interval, 1.10-2.15)...
  93. ncbi request reprint Association of hepatitis C seropositivity with increased risk for developing end-stage renal disease
    Judith I Tsui
    Department of Medicine, University of California, San Francisco, and San Francisco General Hospital, CA 94124, USA
    Arch Intern Med 167:1271-6. 2007
    ..We undertook this study to determine whether having a positive HCV test result was associated with an increased risk for developing treated end-stage renal disease (ESRD)...
  94. ncbi request reprint Racial differences in the progression from chronic renal insufficiency to end-stage renal disease in the United States
    Chi yuan Hsu
    Division of Nephrology, Department of Medicine, University of California, San Francisco, San Francisco, California 94143, USA
    J Am Soc Nephrol 14:2902-7. 2003
    ..The key to understanding black-white differences in ESRD incidence lies in understanding the extreme differences in their progression from CRI to ESRD...
  95. ncbi request reprint Fracture and the risk of coronary events in women with heart disease
    Paul D Varosy
    Department of Medicine, University of California, San Francisco 94143 0124, USA
    Am J Med 115:196-202. 2003
    ..Osteoporosis is associated with aortic calcification and cardiovascular mortality. However, whether skeletal fractures predict the risk of coronary events is unknown...
  96. pmc Association of fetuin-A with mitral annular calcification and aortic stenosis among persons with coronary heart disease: data from the Heart and Soul Study
    Joachim H Ix
    Division of Nephrology, Department of Medicine, Box 0532, HSE 672, University of California, San Francisco, San Francisco, CA 94143 0532, USA
    Circulation 115:2533-9. 2007
    ..Lower serum fetuin-A concentrations are associated with valvular calcification in persons with end-stage renal disease. Whether fetuin-A is associated with valvular calcification in other patient populations is unknown...
  97. pmc Biomarkers to predict recurrent cardiovascular disease: the Heart and Soul Study
    Michael G Shlipak
    Section of General Internal Medicine, San Francisco VA Medical Center, San Francisco, Calif, USA
    Am J Med 121:50-7. 2008
    ..The study purpose was to evaluate the ability of 6 biomarkers to improve the prediction of cardiovascular events among persons with established coronary artery disease...
  98. ncbi request reprint Health and economic benefits of increased beta-blocker use following myocardial infarction
    K A Phillips
    School of Pharmacy and Institute for Health Policy Studies, University of California, San Francisco, 3333 California St, Room 420, Box 0613, San Francisco, CA 94143, USA
    JAMA 284:2748-54. 2000
    ..Understanding the consequences of underuse of beta-blockers is important because of the implications for current policy debates over quality-of-care measures and Medicare prescription drug coverage...
  99. ncbi request reprint Kidney function as a predictor of loss of lean mass in older adults: health, aging and body composition study
    Linda F Fried
    Renal Section, Veterans Affairs Pittsburgh Healthcare System Pittsburgh, Pennsylvania 15240, USA
    J Am Geriatr Soc 55:1578-84. 2007
    ..To assess the association between kidney function and change in body composition in older individuals...
  100. ncbi request reprint Kidney function as a predictor of noncardiovascular mortality
    Linda F Fried
    VA Pittsburgh Healthcare System and Renal Electrolyte Division, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania 15240, USA
    J Am Soc Nephrol 16:3728-35. 2005
    ..Kidney function predicts noncardiovascular mortality from multiple causes in the elderly. Further research is needed to understand the mechanisms and evaluate interventions to reduce the high mortality rate in chronic kidney disease...
  101. ncbi request reprint Cystatin C as a risk factor for outcomes in chronic kidney disease
    Vandana Menon
    Tufts New England Medical Center, Boston, Massachusetts 02111, USA
    Ann Intern Med 147:19-27. 2007
    ....