Research Topics
| W E ShineSummaryAffiliation: University of Texas Southwestern Medical Center Country: USA Publications
| Collaborators
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Detail Information
Publications
Meibomianitis: polar lipid abnormalitiesWard E Shine
Department of Ophthalmology, The University of Texas Southwestern Medical Center at Dallas, Dallas, TX 75390 9057, USA
Cornea 23:781-3. 2004..To determine abnormal meibomian gland secretion polar lipids from meibomianitis patients and to determine the significance of these lipid differences...
Minocycline effect on meibomian gland lipids in meibomianitis patientsW E Shine
Department of Ophthalmology, The University of Texas, Southwestern Medical Center at Dallas, 5323 Harry Hines Blvd, Dallas, TX 75235 9057, USA
Exp Eye Res 76:417-20. 2003..Minocycline may be most effective when the treatment period is longer than 3 months. These results give insight into disease mechanisms associated with chronic blepharitis...
Polar lipids in human meibomian gland secretionsWard E Shine
Department of Ophthalmology, The University of Texas Southwestern Medical Center, Dallas, Texas 75390 9057, USA
Curr Eye Res 26:89-94. 2003..To determine the polar lipid composition of human meibomian gland secretions and their relationship to the preocular tear film...
Short term oral minocycline treatment of meibomianitisJ D Aronowicz
Department of Opthalmology, The University of Texas Southwestern Medical Center at Dallas, Dallas, TX 75390-9057, USA
Br J Ophthalmol 90:856-60. 2006..However, there was improvement in the turbidity of secretions. Short term minocycline therapy probably has efficacy in the management of meibomianitis that extends beyond eradication of bacteria...
Association of meibum oleic acid with meibomian seborrheaW E Shine
Department of Ophthalmology, The University of Texas, Southwestern Medical Center at Dallas, 75235 9057, USA
Cornea 19:72-4. 2000..We sought to determine whether patient meibum fatty acid unsaturation is associated with meibomian gland secretion consistency...
Eyelid disorders: the meibomian gland, blepharitis, and contact lensesJames P McCulley
Department of Ophthalmology, The University of Texas Southwestern Medical Center at Dallas, Dallas, TX 75390 9057, USA
Eye Contact Lens 29:S93-5; discussion S115-8, S192-4. 2003..To present our results to date on the evaluation of the pathophysiology of chronic blepharitis and its relationship to the tear lipid layer, and to propose a structure to that layer...
The lipid layer of tears: dependent on meibomian gland functionJames P McCulley
Department of Ophthalmology, The University of Texas Southwestern Medical Center at Dallas, 5323 Harry Hines Blvd, Dallas, TX 75390 9057, USA
Exp Eye Res 78:361-5. 2004..Before delivery it can be modified by factors such as hormone abnormalities and even after delivery it may be modified by lipases produced by ocular bacteria...
Correlations in a change in aqueous tear evaporation with a change in relative humidity and the impactJames P McCulley
Department of Ophthalmology, The University of Texas Southwestern Medical Center, Dallas, Texas 75390 9057, USA
Am J Ophthalmol 141:758-60. 2006..To establish scientific relationship between relative humidity (RH) and aqueous tear evaporation to elucidate possible significance of this relationship in normals and aqueous tear deficiency patients...
The lipid layer: the outer surface of the ocular surface tear filmJ P McCulley
Department of Ophthalmology, The University of Texas Southwestern Medical Center at Dallas, USA
Biosci Rep 21:407-18. 2001..Finally, lipid layer abnormalities and their relationship to ocular disease are beginning to be clarified...
Meibomian gland and tear film lipids: structure, function and controlJames P McCulley
Department of Ophthalmology, The University of Texas, Southwestern Medical Center at Dallas, Dallas, Texas, USA
Adv Exp Med Biol 506:373-8. 2002
Fourth-generation fluoroquinolone penetration into the aqueous humor in humansJ P McCulley
Department of Ophthalmology, University of Texas Southwestern Medical Center, Dallas, Texas 75390 9057, USA
Ophthalmology 113:955-9. 2006..5% ophthalmic solution and gatifloxacin 0.3% solution in the aqueous humor (AH) in humans after topical application with published levels of other available fluoroquinolones under similar dosing conditions...
Presumed hyposecretory/hyperevaporative KCS: tear characteristicsJames P McCulley
Department of Ophthalmology, University of Texas, Southwestern Medical Center at Dallas, USA
Trans Am Ophthalmol Soc 101:141-52; discussion 152-4. 2003..The role of meibomian gland dropout or slit-lamp MGD in disease is unclear and in our study specifically did not correlate with increased tear evaporation...
Effects of minocycline on the ocular flora of patients with acne rosacea or seborrheic blepharitisChristopher N Ta
Department of Ophthalmology, University of Texas Southwestern Medical Center, 5323 Harry Hines Boulevard, Dallas, Texas 75390, USA
Cornea 22:545-8. 2003..One of the mechanisms of newer generation tetracycline analogues may be a decrease or elimination of bacterial flora from the eyelids...
