Kevin N Sheth
Affiliation: University of Maryland
- Intracranial pressure dose and outcome in traumatic brain injuryKevin N Sheth
Department of Neurology, University of Maryland School of Medicine, Baltimore, MD 21201, USA
Neurocrit Care 18:26-32. 2013..The aim of this study was to determine the association between area under the curve measurement of elevated ICP and clinical outcome...
- Neurocritical care education during neurology residency: AAN survey of US program directorsK N Sheth
Department of Neurology, Neurosurgery, and Emergency Medicine, University of Maryland School of Medicine, Baltimore, MD, USA
Neurology 78:1793-6. 2012..Limited information is available regarding the current state of neurocritical care education for neurology residents. The goal of our survey was to assess the need and current state of neurocritical care training for neurology residents...
- Comparison of hematoma shape and volume estimates in warfarin versus non-warfarin-related intracerebral hemorrhageKevin N Sheth
Division of Neurology, University of Maryland Medical Center, Baltimore, MD, USA
Neurocrit Care 12:30-4. 2010..We examined hematoma shape and methods of volume assessment in patients with OAT-ICH...
- Packed red blood cell transfusion and decreased mortality in intracerebral hemorrhageKevin N Sheth
Department of Neurology, Division of Stroke and Neurocritical Care, University of Maryland Medical Center, Baltimore, Maryland 21201, USA
Neurosurgery 68:1286-92. 2011..Although packed red blood cell (PRBC) transfusion appears to increase brain tissue oxygen, it is unknown whether such transfusions, which are commonly administered in patients with intracranial hemorrhage, alter outcome...
- Autoresuscitation after asystole in patients being considered for organ donationKevin N Sheth
Departments of Neurology, The University of Maryland Medical Center, Baltimore, MD, USA
Crit Care Med 40:158-61. 2012..This study tested the hypothesis that a 2-min observation period after asystole is sufficient for the declaration of death in patients being considered for organ donation after circulatory death...
- Posttreatment variables improve outcome prediction after intra-arterial therapy for acute ischemic strokeShyam Prabhakaran
Department of Neurology, Northwestern University Feinberg School of Medicine, Chicago, Ill, USA
Cerebrovasc Dis 37:356-63. 2014..We sought to derive and validate an outcome prediction score for AIS patients undergoing ERT based on readily available pretreatment and posttreatment factors...
- Pilot study of intravenous glyburide in patients with a large ischemic strokeKevin N Sheth
From the Division of Neurocritical Care and Emergency Neurology, Department of Neurology, Yale University School of Medicine, New Haven, CT K N S Division of Neurocritical Care and Emergency Neurology, Department of Neurology W T K and Division of Neuroradiology, Department of Radiology A J Y, Massachusetts General Hospital, Boston Department of Public Health Services, Medical University of South Carolina, Charleston J J E Department of Neurology, Michael E DeBakey VA Medical, Baylor College of Medicine, Houston, TX T A K, P M Department of Neurology, Klinik und Poliklinik fur Neurologie, Kopf und Neurozentrum, Universitatsklinikum Hamburg Eppendorf, Hamburg, Germany G T Department of Neurology, Melbourne Brain Centre at the Royal Melbourne Hospital, University of Melbourne, Parkville, Australia B C, G A D, S M D Department of Neurology, Stanford University School of Medicine, CA G W A Remedy Pharmaceuticals, Inc, New York, NY S J and Departments of Neurosurgery J M S and Neurology B J S, University of Maryland School of Medicine, Baltimore
Stroke 45:281-3. 2014..We assessed the feasibility of recruiting and treating patients with severe stroke while obtaining preliminary information on the safety and tolerability of RP-1127 (glyburide for injection)...
- Brief episodes of intracranial hypertension and cerebral hypoperfusion are associated with poor functional outcome after severe traumatic brain injuryDeborah M Stein
Division of Critical Care Program in Trauma, R Adams Cowley Shock Trauma Center, University of Maryland School of Medicine, Baltimore, Maryland 21201, USA
J Trauma 71:364-73; discussion 373-4. 2011..The purpose of this study was to establish whether a relationship exists between brief episodes of ICH and CH and outcome after severe TBI...
- Measurement of perihematomal edema in intracerebral hemorrhageSebastian Urday
From the Division of Neurocritical Care and Emergency Neurology, Department of Neurology, Yale University School of Medicine, New Haven, CT S U, L A B, D W G, K N S Center for Human Genetic Research, Division of Neurocritical Care and Emergency Neurology, Department of Neurology, Massachusetts General Hospital, Harvard Medical School, Boston, MA A V, A M A, T W K B, W T K, J R and Stroke Division, Department of Neurology, Beth Israel Deaconess Medical Center, Boston, MA M H S
Stroke 46:1116-9. 2015..PHE measurement on computed tomography (CT) is challenging, and the principles used to detect PHE have not been described fully. We developed a systematic approach for CT-based measurement of PHE...
- Higher volume endovascular stroke centers have faster times to treatment, higher reperfusion rates and higher rates of good clinical outcomesRishi Gupta
Department of Neurology, Emory University School of Medicine, Marcus Stroke and Neuroscience Center, Grady Memorial Hospital, Atlanta, GA, USA
J Neurointerv Surg 5:294-7. 2013..Unfortunately, the sequence of events prior to reperfusion may lead to significant treatment delays. This study sought to determine if high-volume (HV) centers were efficient at delivery of endovascular treatment approaches...
- Glibenclamide in cerebral ischemia and strokeJ Marc Simard
Department of Neurosurgery, University of Maryland School of Medicine, 22 S Greene St, Suite S12D, Baltimore, MD, 21201 1595, USA
Neurocrit Care 20:319-33. 2014..The findings reviewed here provide a strong foundation for a translational research program to study glibenclamide in patients with ischemic stroke...
- Targeting secondary injury in intracerebral haemorrhage--perihaematomal oedemaSebastian Urday
Department of Neurology, Yale University School of Medicine, 333 Cedar Street, New Haven, CT 06510, USA
Nat Rev Neurol 11:111-22. 2015..Our discussion emphasizes that PHO has clinical relevance both as a therapeutic target, owing to its augmentation of the mass effect of a haemorrhage, and as a surrogate marker for novel interventions that target secondary injury. ..
- Prognosis in intracerebral hemorrhageKenneth M Crandall
Department of Neurosurgery, University of Maryland School of Medicine, Baltimore, MD, USA
Rev Neurol Dis 8:23-9. 2011..The use and interpretation of these ever-advancing scales may allow physicians to better predict outcome and assist families in making important care-related decisions...
- Does inhibiting Sur1 complement rt-PA in cerebral ischemia?J Marc Simard
Department of Neurosurgery, University of Maryland School of Medicine, Baltimore, Maryland, USA
Ann N Y Acad Sci 1268:95-107. 2012..Inhibition of Sur1 with injectable glyburide holds promise for ameliorating rt-PA-associated HT in stroke...
- Intravenous rt-PA is not associated with increased risk of hemorrhage in patients with intracranial aneurysmsKevin N Sheth
Department of Neurology, Shock Trauma and Anesthesiology Research Center, University of Maryland School of Medicine, Baltimore, MD, USA
Neurocrit Care 17:199-203. 2012..This study was designed to test the hypothesis that the administration of rt-PA is safe in patients who have an unruptured intracranial aneurysm...
- Advanced modality imaging evaluation in acute ischemic stroke may lead to delayed endovascular reperfusion therapy without improvement in clinical outcomesKevin N Sheth
Department of Neurology, University of Maryland School of Medicine, Baltimore, Maryland, USA
J Neurointerv Surg 5:i62-5. 2013..We studied the effect of advanced modality imaging with CT perfusion (CTP) or MRI compared with non-contrast CT (NCT) in a multicenter cohort...
- Education research: A program perspective on learning how to teachKevin N Sheth
Massachusetts General Hospital, Department of Neurology, 55 Fruit Street, Blake 12 Neuro ICU, Boston, MA 02114, USA
Neurology 70:e75-7. 2008