IRWIN SHERMAN

Summary

Affiliation: University of California
Country: USA

Publications

  1. ncbi request reprint Cytoadherence and sequestration in Plasmodium falciparum: defining the ties that bind
    Irwin W Sherman
    Department of Biology, University of California, Riverside, CA 92521, USA
    Microbes Infect 5:897-909. 2003
  2. ncbi request reprint Cytoadherence of malaria-infected red blood cells involves exposure of phosphatidylserine
    Shigetoshi Eda
    Department of Biology, University of California Riverside, 92521, USA
    Cell Physiol Biochem 12:373-84. 2002
  3. ncbi request reprint Plasmodium falciparum-infected erythrocytes bind to the RGD motif of fibronectin via the band 3-related adhesin
    Shigetoshi Eda
    Department of Biology, University of California, Riverside 92521, USA
    Exp Parasitol 107:157-62. 2004
  4. ncbi request reprint Chemical modifications of band 3 protein affect the adhesion of Plasmodium falciparum-infected erythrocytes to CD36
    Enrique Winograd
    Department of Biology, University of California, Riverside, CA 92521, USA
    Mol Biochem Parasitol 136:243-8. 2004
  5. ncbi request reprint Malaria infection induces a conformational change in erythrocyte band 3 protein
    Enrique Winograd
    Department of Biology, University of California, Riverside, CA 92521, USA
    Mol Biochem Parasitol 138:83-7. 2004
  6. ncbi request reprint Band 3 clustering promotes the exposure of neoantigens in Plasmodium falciparum-infected erythrocytes
    Enrique Winograd
    Department of Biology, University of California, Riverside, CA 92521, USA
    Mol Biochem Parasitol 142:98-105. 2005
  7. ncbi request reprint Identification of peptides targeting the surface of Plasmodium falciparum-infected erythrocytes using a phage display peptide library
    Keiko Eda
    Department of Biology, University of California, Riverside, California 92521, USA
    Am J Trop Med Hyg 71:190-5. 2004

Research Grants

  1. ERYTHROCYTE ADHESION IN FALCIPARUM MALARIA
    IRWIN SHERMAN; Fiscal Year: 2004

Collaborators

  • Enrique Winograd
  • Shigetoshi Eda
  • Keiko Eda
  • Jacques G Prudhomme

Detail Information

Publications7

  1. ncbi request reprint Cytoadherence and sequestration in Plasmodium falciparum: defining the ties that bind
    Irwin W Sherman
    Department of Biology, University of California, Riverside, CA 92521, USA
    Microbes Infect 5:897-909. 2003
    ..e. thrombospondin, CD36, ICAM-1 (intercellular adhesion molecule), and chondroitin sulfate...
  2. ncbi request reprint Cytoadherence of malaria-infected red blood cells involves exposure of phosphatidylserine
    Shigetoshi Eda
    Department of Biology, University of California Riverside, 92521, USA
    Cell Physiol Biochem 12:373-84. 2002
    ..In conclusion, these results demonstrate that PS exposed on the surface of malaria-infected red cells contributes, in part, to the adherence of P. falciparum-parasitized red cells to CD36 and thrombospondin...
  3. ncbi request reprint Plasmodium falciparum-infected erythrocytes bind to the RGD motif of fibronectin via the band 3-related adhesin
    Shigetoshi Eda
    Department of Biology, University of California, Riverside 92521, USA
    Exp Parasitol 107:157-62. 2004
    ..Since fibronectin occurs on endothelial cells and platelets, this interaction may contribute to the binding of falciparum-infected erythrocytes to such host cells...
  4. ncbi request reprint Chemical modifications of band 3 protein affect the adhesion of Plasmodium falciparum-infected erythrocytes to CD36
    Enrique Winograd
    Department of Biology, University of California, Riverside, CA 92521, USA
    Mol Biochem Parasitol 136:243-8. 2004
    ..The results suggest that host membrane proteins such as AE1 contribute to the adhesion of malaria-infected erythrocytes to CD36...
  5. ncbi request reprint Malaria infection induces a conformational change in erythrocyte band 3 protein
    Enrique Winograd
    Department of Biology, University of California, Riverside, CA 92521, USA
    Mol Biochem Parasitol 138:83-7. 2004
    ..This report identifies a conformational change in a region of band 3 protein involved in the enhanced adhesiveness of P. falciparum-infected erythrocytes...
  6. ncbi request reprint Band 3 clustering promotes the exposure of neoantigens in Plasmodium falciparum-infected erythrocytes
    Enrique Winograd
    Department of Biology, University of California, Riverside, CA 92521, USA
    Mol Biochem Parasitol 142:98-105. 2005
    ..Thus, a parasite-induced modification of band 3 promotes adhesion and induces antigenic changes in the P. falciparum-infected erythrocyte...
  7. ncbi request reprint Identification of peptides targeting the surface of Plasmodium falciparum-infected erythrocytes using a phage display peptide library
    Keiko Eda
    Department of Biology, University of California, Riverside, California 92521, USA
    Am J Trop Med Hyg 71:190-5. 2004
    ..Our results demonstrate that the P1 peptide may be a lead compound for the development of anti-malarial agents targeting the surface of iRBCs...

Research Grants5

  1. ERYTHROCYTE ADHESION IN FALCIPARUM MALARIA
    IRWIN SHERMAN; Fiscal Year: 2004
    ..e. peptidomimetics, small molecules, antibodies) that could inhibit or reverse sequestration thus allowing for better and safer therapeutic modalities for individuals suffering from falciparum malaria. ..