David S Sheps
Affiliation: University of Florida
- Mental stress-induced ischemia and all-cause mortality in patients with coronary artery disease: Results from the Psychophysiological Investigations of Myocardial Ischemia studyDavid S Sheps
University of Florida College of Medicine, the Malcom Randall Veterans Affairs Medical Center, and the Medical Research Service of the Department of Veterans Affairs, Gainesville, Fla 32610 0277, USA
Circulation 105:1780-4. 2002..Ischemia during laboratory mental stress tests has been linked to significantly higher rates of adverse cardiac events. Previous studies have not been designed to detect differences in mortality rates...
- Sex differences in chest pain in patients with documented coronary artery disease and exercise-induced ischemia: Results from the PIMI studyD S Sheps
University of Florida College of Medicine, Gainesville, FL 32610 0277, USA
Am Heart J 142:864-71. 2001..Sex differences in the pathophysiologic course of coronary artery disease (CAD) are widely recognized, yet accurate diagnosis of coronary artery disease in women remains challenging...
- Chest pain in patients with cardiac and noncardiac diseaseDavid S Sheps
University of Florida and the Malcom Randall VA Medical Center, P O Box 100181, Gainesville, FL 100181 0181, USA
Psychosom Med 66:861-7. 2004..To describe factors influencing chest pain expression in patients with cardiac or noncardiac disease...
- Variability of myocardial ischemic responses to mental versus exercise or adenosine stress in patients with coronary artery diseaseMustafa Hassan
Division of Cardiology, Department of Medicine, University of Florida, Gainesville, FL, USA
J Nucl Cardiol 15:518-25. 2008..In this study we sought to compare the within-individual ischemic responses to mental versus exercise or adenosine stress in a cohort of CAD patients...
- Do men and women differ on measures of mental stress-induced ischemia?Kaki M York
Cardiovascular Research, Department of Medicine, University of Florida, Gainesville, Florida, USA
Psychosom Med 69:918-22. 2007..However, little is known about the effects of mental stress on ischemic processes in women. Most studies to date either had few women or required a positive exercise stress test...
- Usefulness of peripheral arterial tonometry in the detection of mental stress-induced myocardial ischemiaMustafa Hassan
Division of Cardiology, Department of Medicine, University of Florida, Gainesville, Florida, USA
Clin Cardiol 32:E1-6. 2009..Peripheral arterial vasoconstriction has been consistently reported as an underlying mechanism for ischemia development in this setting and as such affords a unique opportunity for the noninvasive detection of this phenomenon...
- Comparison of peripheral arterial response to mental stress in men versus women with coronary artery diseaseMustafa Hassan
Cardiovascular Research, Division of Cardiology, Department of Medicine, University of Florida, Gainesville, Florida, USA
Am J Cardiol 102:970-4. 2008..This finding may suggest that men have higher susceptibility to mental stress-related adverse effects. Additional studies are needed to determine the significance of this finding...
- Coronary artery disease and depression: patients with more depressive symptoms have lower cardiovascular reactivity during laboratory-induced mental stressKaki M York
Cardiovascular Research, Department of Medicine, University of Florida, Gainesville, FL, USA
Psychosom Med 69:521-8. 2007..Some researchers have proposed that negative outcomes in depressed patients with CAD may be related to exaggerated cardiovascular reactivity and psychological stress. However, the data are unclear...
- Association of beta1-adrenergic receptor genetic polymorphism with mental stress-induced myocardial ischemia in patients with coronary artery diseaseMustafa Hassan
Cardiovascular Research, Division of Cardiology, Department of Medicine, College of Pharmacy, University of Florida, 1601 SW Archer Rd, Code 111 D, Gainesville, FL 32608, USA
Arch Intern Med 168:763-70. 2008....
- The effect of acute psychological stress on QT dispersion in patients with coronary artery diseaseMustafa Hassan
Division of Cardiology, Department of Medicine, University of Florida, Gainesville, Florida, USA
Pacing Clin Electrophysiol 32:1178-83. 2009..Mental stress-induced myocardial ischemia occurs in a significant percentage of the CAD population. It is unknown if the proarrhythmic effects of psychological stress are mediated through the development of myocardial ischemia...
- Mental stress provokes ischemia in coronary artery disease subjects without exercise- or adenosine-induced ischemiaSrikanth Ramachandruni
University of Florida, Gainesville, Florida 32608, USA
J Am Coll Cardiol 47:987-91. 2006..The study population consisted solely of those with negative test results...
- Psychobiology of depression/distress in congestive heart failureKaki M York
VAMC, Psychology Service 116B, North Florida South Georgia VA Healthcare System, 1601 SW Archer Rd, Gainesville, FL 32608, USA
Heart Fail Rev 14:35-50. 2009..These mechanisms are reviewed in this article. Additional novel mechanisms such as mental stress-induced myocardial ischemia are also discussed...
- Detection and reproducibility of mental stress-induced myocardial ischemia with Tc-99m sestamibi SPECT in normal and coronary artery disease populationsChin K Kim
Division of Cardiovascular Medicine, University of Florida, Gainesville, Fla, USA
J Nucl Cardiol 10:56-62. 2003....
- Mental stress-induced myocardial ischemia in coronary artery disease patients with left ventricular dysfunctionMustafa Hassan
Cardiovascular Research, Division of Cardiology, Department of Medicine, University of Florida, Gainesville, FL, USA
J Nucl Cardiol 14:308-13. 2007..Mental stress-induced myocardial ischemia (MSIMI) also identifies a subset of CAD patients at increased risk for future cardiovascular events. Susceptibility to MSIMI in patients with CAD and reduced LVEF is unknown...
- Acute and chronic psychological stress in coronary diseaseSrikanth Ramachandruni
Department of Medicine, University of Florida College of Medicine, Gainesville, Florida 32610 0277, USA
Curr Opin Cardiol 19:494-9. 2004..It is well recognized that stress can be harmful to the cardiovascular system. The combination of the preexisting vulnerability and the major stressor are believed to result in cardiac arrhythmias and/or plaque rupture leading to death...
- Pharmacological treatment of patients with peripheral arterial diseaseChin K Kim
Cardiology Section, Department of Veterans Affairs, Medical Service, Malcom Randall VA Medical Center, Gainesville, Florida, USA
Drugs 63:637-47. 2003..With aggressive risk factor modification and adequate pharmacotherapy, patients with peripheral arterial disease can have an improved quality of life as well as prolonged survival...
- Are heart rate and blood pressure responses to mental stress predictive of clinical cardiovascular events? The answer varies by coronary artery disease syndromeDavid S Sheps
Am Heart J 146:197-8. 2003
- Social networks and incident stroke among women with suspected myocardial ischemiaThomas Rutledge
Department of Psychiatry, VA San Diego Healthcare System, University of California, San Diego, CA 92161, USA
Psychosom Med 70:282-7. 2008..Social networks are an independent predictor of all-cause and cardiovascular mortality, but their relationship with stroke events in at-risk populations is largely unknown...
- Anger, hostility, and cardiac symptoms in women with suspected coronary artery disease: the Women's Ischemia Syndrome Evaluation (WISE) StudyDavid S Krantz
Department of Medical and Clinical Psychology, Uniformed Services University of Health Sciences, Bethesda, Maryland 20814, USA
J Womens Health (Larchmt) 15:1214-23. 2006..To determine the relationship of anger and hostility to angiographic coronary artery disease (CAD), symptoms, and functional status among women with suspected CAD...
- Panic attacks, daily life ischemia, and chest pain in postmenopausal womenJordan W Smoller
Department of Psychiatry, Massachusetts General Hospital, Boston, Massachusetts, USA
Psychosom Med 68:824-32. 2006..Chest pain is a common symptom of panic attacks, but little is known about the relationship in older women among panic attacks, chest pain, and daily life ischemia...
- Depressive symptoms predict heart rate recovery after exercise treadmill testing in patients with coronary artery disease: results from the Psychophysiological Investigation of Myocardial Ischemia studyJoel W Hughes
Kent State University, Kent, Ohio, USA
Psychosom Med 70:456-60. 2008..The purpose of this study was to determine whether depressive symptoms are associated with low heart rate variability (HRV) and prolonged HR recovery after exercise testing in patients with coronary artery disease (CAD)...
- Depressive symptoms and heart rate variability in postmenopausal womenChin K Kim
Division of Cardiovascular Medicine, University of Florida, Gainesville 32610 0277, USA
Arch Intern Med 165:1239-44. 2005..Findings regarding a relationship between depressive symptoms and heart rate variability that could explain increased cardiovascular risk have been inconsistent across studies...
- Depression is a risk factor for mortality in coronary heart diseaseRobert M Carney
Psychosom Med 66:799-801. 2004
- The INTERHEART study: intersection between behavioral and general medicineDavid S Sheps
Psychosom Med 66:797-8. 2004
- Cognitive and somatic symptoms of depression are associated with medical comorbidity in patients after acute myocardial infarctionLana L Watkins
Department of Psychiatry and Behavioral Sciences, Duke University, Durham, NC, USA
Am Heart J 146:48-54. 2003..However, the extent to which clinical depression is related to comorbid medical conditions is unknown. This study examined the degree of association between clinical depression and medical comorbidity in patients hospitalized with AMI...
- Depression and coronary heart disease: recommendations for screening, referral, and treatment: a science advisory from the American Heart Association Prevention Committee of the Council on Cardiovascular Nursing, Council on Clinical Cardiology, Council onJudith H Lichtman
Circulation 118:1768-75. 2008..This multispecialty consensus document reviews the evidence linking depression with CHD and provides recommendations for healthcare providers for the assessment, referral, and treatment of depression...
- ENRICHD and SADHART: implications for future biobehavioral intervention effortsDavid S Sheps
Psychosom Med 65:1-2. 2003
- Walking compared with vigorous exercise for the prevention of cardiovascular events in womenJoAnn E Manson
Division of Preventive Medicine, Harvard Medical School and Brigham and Women s Hospital, Boston 02215, USA
N Engl J Med 347:716-25. 2002..The role of walking, as compared with vigorous exercise, in the prevention of cardiovascular disease remains controversial. Data for women who are members of minority racial or ethnic groups are particularly sparse...
- Depression, the metabolic syndrome and cardiovascular riskViola Vaccarino
Division of Cardiology, Department of Medicine, Emory University School of Medicine, 1256 Briarcliff Road NE, Suite 1 North, Atlanta, GA 30306, USA
Psychosom Med 70:40-8. 2008..The relationship between depression and the metabolic syndrome is unclear, and whether metabolic syndrome explains the association between depression and cardiovascular disease (CVD) risk is unknown...
- Depression, inflammation, and incident cardiovascular disease in women with suspected coronary ischemia: the National Heart, Lung, and Blood Institute-sponsored WISE studyViola Vaccarino
Department of Medicine, Division of Cardiology, Emory University School of Medicine, Atlanta, Georgia 30306, USA
J Am Coll Cardiol 50:2044-50. 2007..The purpose of this study was to examine prospectively whether inflammation explains the relationship between depression and cardiovascular disease (CVD)...
- Psychological stress and myocardial ischemia: understanding the link and the implicationsDavid S Sheps
Psychosom Med 69:491-2. 2007
- Depression as a risk factor for post-MI mortalityRobert M Carney
J Am Coll Cardiol 44:472; author reply 473-4. 2004
- A population-based evaluation of the thrombolysis in myocardial infarction risk score for unstable angina and non-ST elevation myocardial infarctionBeth A Bartholomew
William Beaumont Hospital, Royal Oak, Michigan 48073, USA
Clin Cardiol 27:74-8. 2004....
- Mood disorders in the medically ill: scientific review and recommendationsDwight L Evans
School of Medicine, University of Pennsylvania, 423 Guardian Drive, Philadelphia, PA 19104, USA
Biol Psychiatry 58:175-89. 2005....
- Women's Ischemic Syndrome Evaluation: current status and future research directions: report of the National Heart, Lung and Blood Institute workshop: October 2-4, 2002: Section 2: stable ischemia: pathophysiology and gender differencesRita F Redberg
Circulation 109:e47-9. 2004
- Prevalence and correlates of panic attacks in postmenopausal women: results from an ancillary study to the Women's Health InitiativeJordan W Smoller
Department of Psychiatry, Massachusetts General Hospital, Boston, MA 02114, USA
Arch Intern Med 163:2041-50. 2003..Panic attacks are known to be more common in women than in men, but the prevalence and correlates of panic in the postmenopausal period have not been well defined...
- Assessment and treatment of depression in patients with cardiovascular disease: National Heart, Lung, and Blood Institute Working Group ReportKarina W Davidson
Department of Medicine, Columbia University College of Physicians and Surgeons, 622 W 168th St, PH9 Center, Room 941, New York, NY 10032, USA
Psychosom Med 68:645-50. 2006..The National Heart, Lung, and Blood Institute convened an interdisciplinary working group of experts to develop recommendations for the assessment and treatment of depression in patients with coronary heart disease (CHD)...
- The Editor's Roundtable: major depression in patients with coronary heart diseaseVincent E Friedewald
The University of Texas Health Sciences Center at Houston, Houston, Texas, USA
Am J Cardiol 99:519-29. 2007
- Peripheral arterial tonometry: a diagnostic method for detection of myocardial ischemia induced during mental stress tests: a pilot studyDaniel A Goor
Cardiovascular Medicine, Tel Aviv University, Tel Aviv, Israel
Clin Cardiol 27:137-41. 2004..It has been shown recently that myocardial ischemia induced during mental stress tests is specifically associated with peripheral arterial vasoconstriction...
- Assessment and treatment of depression in patients with cardiovascular disease: National Heart, Lung, and Blood Institute working group reportKarina W Davidson
Department of Medicine, Columbia University College of Physicians and Surgeons, New York, NY 10032, USA, and Centre Hospitalier de l Universite de Montreal Research Center, Quebec, Canada
Ann Behav Med 32:121-6. 2006