Zhong Jian Shen

Summary

Affiliation: University of Wisconsin
Country: USA

Publications

  1. ncbi request reprint Antisense targeting of TGF-beta1 augments BMP-induced upregulation of osteopontin, type I collagen and Cbfa1 in human Saos-2 cells
    Zhong Jian Shen
    Department of Biochemistry, College of Natural Sciences, Kyungpook National University, Taegu 702 701, Korea
    Exp Cell Res 313:1415-25. 2007
  2. ncbi request reprint Negative regulation of bone morphogenetic protein/Smad signaling by Cas-interacting zinc finger protein in osteoblasts
    Zhong Jian Shen
    Department of Molecular Pharmacology, Medical Research Institute, Tokyo Medical and Dental University, 3 10 Kanda Sunugadai 2 Chome Chiyoda ku, Tokyo, 101 Japan
    J Biol Chem 277:29840-6. 2002
  3. pmc The nucleocytoplasmic shuttling protein CIZ reduces adult bone mass by inhibiting bone morphogenetic protein-induced bone formation
    Mikihiko Morinobu
    Department of Molecular Pharmacology, Tokyo Medical and Dental University, Tokyo, Japan
    J Exp Med 201:961-70. 2005
  4. ncbi request reprint The peptidyl-prolyl isomerase Pin1 regulates granulocyte-macrophage colony-stimulating factor mRNA stability in T lymphocytes
    Stephane Esnault
    Waisman Center for Developmental Disabilities, Department of Pathology and Laboratory Medicine, University of Wisconsin School of Medicine, Madison, WI 53705, USA
    J Immunol 177:6999-7006. 2006

Collaborators

Detail Information

Publications4

  1. ncbi request reprint Antisense targeting of TGF-beta1 augments BMP-induced upregulation of osteopontin, type I collagen and Cbfa1 in human Saos-2 cells
    Zhong Jian Shen
    Department of Biochemistry, College of Natural Sciences, Kyungpook National University, Taegu 702 701, Korea
    Exp Cell Res 313:1415-25. 2007
    ..These data suggest autocrine TGF-beta1 antagonizes BMP signaling through modulation of inducible Smad6 and the activity of BMP specific Smad1/5...
  2. ncbi request reprint Negative regulation of bone morphogenetic protein/Smad signaling by Cas-interacting zinc finger protein in osteoblasts
    Zhong Jian Shen
    Department of Molecular Pharmacology, Medical Research Institute, Tokyo Medical and Dental University, 3 10 Kanda Sunugadai 2 Chome Chiyoda ku, Tokyo, 101 Japan
    J Biol Chem 277:29840-6. 2002
    ..Finally, CIZ overexpression suppressed the formation of mineralized nodules in osteoblastic cell cultures. These data indicate that CIZ is a novel type inhibitor of BMP/Smad signaling...
  3. pmc The nucleocytoplasmic shuttling protein CIZ reduces adult bone mass by inhibiting bone morphogenetic protein-induced bone formation
    Mikihiko Morinobu
    Department of Molecular Pharmacology, Tokyo Medical and Dental University, Tokyo, Japan
    J Exp Med 201:961-70. 2005
    ..Finally, BMP-2-induced bone formation on adult mouse calvariae in vivo was enhanced by CIZ deficiency. These results establish that CIZ suppresses the levels of adult bone mass through inhibition of BMP-induced activation of osteoblasts...
  4. ncbi request reprint The peptidyl-prolyl isomerase Pin1 regulates granulocyte-macrophage colony-stimulating factor mRNA stability in T lymphocytes
    Stephane Esnault
    Waisman Center for Developmental Disabilities, Department of Pathology and Laboratory Medicine, University of Wisconsin School of Medicine, Madison, WI 53705, USA
    J Immunol 177:6999-7006. 2006
    ..Mechanistically, Pin1 mediated the association of the AU-rich element-binding protein, AUF1, with GM-CSF mRNA, which determined the rate of decay by the exosome...