Jason P Sheehan

Summary

Affiliation: University of Virginia
Country: USA

Publications

  1. ncbi Gamma knife surgery for glioblastoma multiforme
    R Webster Crowley
    Department of Neurological Surgery, University of Virginia Health System, Charlottesville, Virginia 22908 0212, USA
    Neurosurg Focus 20:E17. 2006
  2. ncbi Gamma knife surgery for trigeminal schwannoma
    Jason Sheehan
    Lars Leksell Gamma Knife Center, Department of Neurological Surgery, University of Virginia Health System, Charlottesville, Virginia 22908, USA
    J Neurosurg 106:839-45. 2007
  3. pmc Gamma knife radiosurgery of meningiomas involving the foramen magnum
    Robert M Starke
    Department of Neurological Surgery, University of Virginia, Charlottesville, VA, USA
    J Craniovertebr Junction Spine 1:23-8. 2010
  4. ncbi Identification of knowledge gaps in neurosurgery through analysis of responses to the Self-Assessment in Neurological Surgery (SANS)
    Jason Sheehan
    Department of Neurological Surgery, University of Virginia, Charlottesville, Virginia, USA Electronic address
    World Neurosurg 81:229-33. 2014
  5. pmc A multi-national report on methods for institutional credentialing for spine radiosurgery
    Peter C Gerszten
    University of Pittsburgh Medical Center, Pittsburgh, PA, USA
    Radiat Oncol 8:158. 2013
  6. doi Inhibition of glioblastoma and enhancement of survival via the use of mibefradil in conjunction with radiosurgery
    Jason P Sheehan
    Department of Neurological Surgery, University of Virginia, Charlottesville, VA 22908, USA
    J Neurosurg 118:830-7. 2013
  7. ncbi Pathological findings following radiosurgery of pituitary adenomas
    Jason Sheehan
    Department of Neurological Surgery, University of Virginia, Charlottesville, VA 22908, USA
    Prog Neurol Surg 20:172-9. 2007
  8. ncbi Gamma knife surgery-induced meningioma. Report of two cases and review of the literature
    Jason Sheehan
    Lars Leksell Center for Gamma Surgery, Department of Neurological Surgery, University of Virginia Health System, Charlottesville, Virginia 22908, USA
    J Neurosurg 105:325-9. 2006
  9. doi Gamma Knife surgery for pituitary adenomas: factors related to radiological and endocrine outcomes
    Jason P Sheehan
    Department of Neurological Surgery, University of Virginia Health System, Charlottesville, Virginia 22908, USA
    J Neurosurg 114:303-9. 2011
  10. ncbi Pituitary adenomas: is Gamma Knife radiosurgery safe?
    Jason Sheehan
    University of Virginia Health Sciences Center, VA, USA
    Nat Clin Pract Endocrinol Metab 1:2-3. 2005

Detail Information

Publications89

  1. ncbi Gamma knife surgery for glioblastoma multiforme
    R Webster Crowley
    Department of Neurological Surgery, University of Virginia Health System, Charlottesville, Virginia 22908 0212, USA
    Neurosurg Focus 20:E17. 2006
    ..In this paper, the authors review the pathophysiological mechanisms of GKS and its applications for GBM management...
  2. ncbi Gamma knife surgery for trigeminal schwannoma
    Jason Sheehan
    Lars Leksell Gamma Knife Center, Department of Neurological Surgery, University of Virginia Health System, Charlottesville, Virginia 22908, USA
    J Neurosurg 106:839-45. 2007
    ..In this article the authors evaluate the radiological and clinical outcomes in a series of patients in whom Gamma Knife surgery (GKS) was used to treat trigeminal schwannomas...
  3. pmc Gamma knife radiosurgery of meningiomas involving the foramen magnum
    Robert M Starke
    Department of Neurological Surgery, University of Virginia, Charlottesville, VA, USA
    J Craniovertebr Junction Spine 1:23-8. 2010
    ..For some patients, stereotactic radiosurgery may be used as the primary treatment modality. We evaluatedthe long-term outcome of Gamma Knife radiosurgery (GKRS) for the treatment of patientswith a foramen magnum meningioma...
  4. ncbi Identification of knowledge gaps in neurosurgery through analysis of responses to the Self-Assessment in Neurological Surgery (SANS)
    Jason Sheehan
    Department of Neurological Surgery, University of Virginia, Charlottesville, Virginia, USA Electronic address
    World Neurosurg 81:229-33. 2014
    ..To examine the gaps in knowledge of neurosurgeons responding to the Self-Assessment in Neurological Surgery (SANS)...
  5. pmc A multi-national report on methods for institutional credentialing for spine radiosurgery
    Peter C Gerszten
    University of Pittsburgh Medical Center, Pittsburgh, PA, USA
    Radiat Oncol 8:158. 2013
    ..This article describes the methods for institutional credentialing for spine radiosurgery at seven highly experienced international institutions...
  6. doi Inhibition of glioblastoma and enhancement of survival via the use of mibefradil in conjunction with radiosurgery
    Jason P Sheehan
    Department of Neurological Surgery, University of Virginia, Charlottesville, VA 22908, USA
    J Neurosurg 118:830-7. 2013
    ..In vivo study of mibefradil and radiosurgery is lacking. The authors used an intracranial C6 glioma model in rats to study tumor response to mibefradil and radiosurgery...
  7. ncbi Pathological findings following radiosurgery of pituitary adenomas
    Jason Sheehan
    Department of Neurological Surgery, University of Virginia, Charlottesville, VA 22908, USA
    Prog Neurol Surg 20:172-9. 2007
    ..Further study must be performed to determine the histological changes that accompany the frequently beneficial effects of radiosurgery in recurrent or residual pituitary adenomas...
  8. ncbi Gamma knife surgery-induced meningioma. Report of two cases and review of the literature
    Jason Sheehan
    Lars Leksell Center for Gamma Surgery, Department of Neurological Surgery, University of Virginia Health System, Charlottesville, Virginia 22908, USA
    J Neurosurg 105:325-9. 2006
    ..These cases and the few others detailed in the literature emphasize the need for long-term neurosurgical follow-up review in patients after radiosurgery...
  9. doi Gamma Knife surgery for pituitary adenomas: factors related to radiological and endocrine outcomes
    Jason P Sheehan
    Department of Neurological Surgery, University of Virginia Health System, Charlottesville, Virginia 22908, USA
    J Neurosurg 114:303-9. 2011
    ..This study evaluates a large cohort of patients with a pituitary adenoma to characterize factors related to endocrine remission, control of tumor growth, and development of pituitary deficiency...
  10. ncbi Pituitary adenomas: is Gamma Knife radiosurgery safe?
    Jason Sheehan
    University of Virginia Health Sciences Center, VA, USA
    Nat Clin Pract Endocrinol Metab 1:2-3. 2005
  11. ncbi Potentiation of neurite outgrowth and reduction of apoptosis by immunosuppressive agents: implications for neuronal injury and transplantation
    Jason Sheehan
    Department of Neurological Surgery, University of Virginia Health System, Charlottesville, Virginia 22908, USA
    Neurosurg Focus 20:E9. 2006
    ..In this study, the authors evaluate the effect of immunosuppressive medications on neurite outgrowth and cell survival after a pharmacologically induced injury...
  12. doi Review of spinal radiosurgery: a minimally invasive approach for the treatment of spinal and paraspinal metastases
    Jason P Sheehan
    Department of Neurosurgery, University of Virginia Health Sciences Center, Charlottesville, Virginia 22908, USA
    Neurosurg Focus 25:E18. 2008
    ..Spinal radiosurgery has expanded the neurosurgical treatment armamentarium for patients with spinal and paraspinal metastasis...
  13. doi Use of trans sodium crocetinate for sensitizing glioblastoma multiforme to radiation: laboratory investigation
    Jason Sheehan
    Department of Neurological Surgery, University of Virginia Health System, Charlottesville, VA 22908, USA
    J Neurosurg 108:972-8. 2008
    ..Trans sodium crocetinate (TSC) has been shown to increase oxygen diffusion in the brain and elevate the partial brain oxygen level. The goal of this study was to evaluate the radiosensitizing effects of TSC on GBM tumors...
  14. doi Temozolomide-induced inhibition of pituitary adenoma cells
    Jason Sheehan
    Department of Neurological Surgery, University of Virginia Health Sciences Center, Charlottesville, Virginia 22908, USA
    J Neurosurg 114:354-8. 2011
    ..The effectiveness of temozolomide in terms of growth suppression and decreased hormonal production is evaluated...
  15. doi Timing and risk factors for new brain metastasis formation in patients initially treated only with Gamma Knife surgery. Clinical article
    Jason P Sheehan
    Department of Neurological Surgery, University of Virginia Health System, Charlottesville, Virginia, USA
    J Neurosurg 114:763-8. 2011
    ..This study evaluates the timing, number, and risk factors for development of subsequent new brain metastasis in a group of patients treated with stereotactic radiosurgery alone...
  16. doi Resident perceptions of radiosurgical training and the effect of a focused resident training seminar
    Jason P Sheehan
    Department of Neurological Surgery, University of Virginia Health System, Charlottesville, Virginia 22908, USA
    J Neurosurg 113:59-63. 2010
    ..This study evaluates the opinions of residents on current radiosurgical training and the effect of a focused educational course on those residents...
  17. doi Trans-sodium crocetinate enhancing survival and glioma response on magnetic resonance imaging to radiation and temozolomide
    Jason Sheehan
    Department of Neurological Surgery, University of Virginia Health System, Charlottesville, Virginia, USA
    J Neurosurg 113:234-9. 2010
    ..The authors examined whether this improvement in intratumor oxygenation translates to a therapeutic advantage when delivering standard adjuvant treatment to GBs...
  18. doi Gamma Knife radiosurgery for trigeminal neuralgia: the impact of magnetic resonance imaging-detected vascular impingement of the affected nerve
    Jason P Sheehan
    Department of Neurological Surgery, University of Virginia, Charlottesville, Virginia, USA
    J Neurosurg 113:53-8. 2010
    ....
  19. doi Stereotactic radiosurgery for WHO grade I meningiomas
    Jason P Sheehan
    Department of Neurological Surgery, University of Virginia Health Sciences Center, Charlottesville, Virginia 22908, USA
    J Neurooncol 99:407-16. 2010
    ..Longitudinal follow-up including neurologic and radiologic assessment is required. Single and multisession stereotactic radiosurgery will likely play an expanded role in the treatment of patients with meningiomas...
  20. doi Trans sodium crocetinate: functional neuroimaging studies in a hypoxic brain tumor
    Jason P Sheehan
    Department of Neurological Surgery, University of Virginia Health System, Charlottesville, Virginia 22908, USA
    J Neurosurg 115:749-53. 2011
    ..In this research, the authors use oxygen-sensitive PET studies to evaluate the extent of hypoxia in vivo in a glioblastoma model and the effect of TSC on the baseline oxygenation of the tumor...
  21. ncbi Effect of trans sodium crocetinate on brain tumor oxygenation. Laboratory investigation
    Jason Sheehan
    Department of Neurological Surgery, University of Virginia Health System, Charlottesville, Virginia, USA
    J Neurosurg 111:226-9. 2009
    ..Trans sodium crocetinate (TSC) has been shown to be a radiosensitizer. The goal of this research was to elucidate the underlying mechanism of TSC's radiosensitizing effect...
  22. ncbi Stereotactic radiosurgery for pituitary adenomas: a review of the literature and our experience
    Jason P Sheehan
    Lars Leksell Gamma Knife Center, Department of Neurological Surgery, Health Sciences Center, University of Virginia, Charlottesville, VA 22908, USA
    Front Horm Res 34:185-205. 2006
    ....
  23. ncbi Radiosurgery in patients with renal cell carcinoma metastasis to the brain: long-term outcomes and prognostic factors influencing survival and local tumor control
    Jason P Sheehan
    Department of Neurological Surgery, University of Pittsburgh, University of Pittsburgh Medical Center, Presbyterian Hospital, Pittsburgh, Pennsylvania, USA
    J Neurosurg 98:342-9. 2003
    ..In this study the authors examined the efficacy of gamma knife surgery in treating renal cell carcinoma metastases to the brain and evaluated factors affecting long-term survival...
  24. ncbi The safety and utility of recombinant human bone morphogenetic protein-2 for cranial procedures in a nonhuman primate model
    Jason P Sheehan
    Department of Neurological Surgery and Neurology, University of Virginia, Charlottesville, Virginia 22908, USA
    J Neurosurg 98:125-30. 2003
    ..The goal of this study was to evaluate the safety and efficacy of recombinant human bone morphogenetic protein 2 (rhBMP-2) in cranial applications...
  25. ncbi Gamma knife surgery for glomus jugulare tumors: an intermediate report on efficacy and safety
    Jason Sheehan
    Department of Neurological Surgery, University of Virginia, Charlottesville, Virginia 22908, USA
    J Neurosurg 102:241-6. 2005
    ..Despite these therapies, tumor control can be difficult to achieve particularly without undo risk of patient morbidity or mortality. The authors examine the safety and efficacy of gamma knife surgery (GKS) for glomus jugulare tumors...
  26. ncbi Radiosurgery for residual or recurrent nonfunctioning pituitary adenoma
    Jason P Sheehan
    Department of Neurosurgery, The Center for Image Guided Surgery, University of Pittsburgh Medical Center Presbyterian, Pittsburgh, Pennsylvania, USA
    J Neurosurg 97:408-14. 2002
    ..The purpose of this retrospective study is to evaluate the efficacy and role of gamma knife radiosurgery (GKS) in the management of residual or recurrent nonfunctioning pituitary adenomas...
  27. ncbi Radiosurgery for non-small cell lung carcinoma metastatic to the brain: long-term outcomes and prognostic factors influencing patient survival time and local tumor control
    Jason P Sheehan
    Department of Neurological Surgery, University of Pittsburgh Medical Center, Presbyterian Hospital, Pittsburgh, Pennsylvania, USA
    J Neurosurg 97:1276-81. 2002
    ..The authors examine the efficacy of gamma knife radiosurgery (GKS) for treating non-small cell lung carcinoma (NSCLC) metastases to the brain and evaluate factors affecting long-term patient survival...
  28. ncbi Thoracic diastematomyelia with concurrent intradural epidermoid spinal cord tumor and cervical syrinx in an adult. Case report
    Jason P Sheehan
    Department of Neurological Surgery, University of Virginia Health Sciences Center, Charlottesville 22908, USA
    J Neurosurg 97:231-4. 2002
    ..Thorough neuraxis radiographic evaluation and surgical treatment are usually indicated...
  29. ncbi Radiosurgery for patients with recurrent small cell lung carcinoma metastatic to the brain: outcomes and prognostic factors
    Jason Sheehan
    Department of Neurological Surgery, University of Virginia, Charlottesville, Virginia 22908, USA
    J Neurosurg 102:247-54. 2005
    ....
  30. ncbi Radiosurgery for treatment of recurrent intracranial hemangiopericytomas
    Jason Sheehan
    Department of Neurological Surgery, Center for Image Guided Neurosurgery, University of Pittsburgh Medical Center, Pennsylvania, USA
    Neurosurgery 51:905-10; discussion 910-1. 2002
    ..The purpose of this retrospective, single-institution review was to evaluate the efficacy and role of stereotactic radiosurgery in the management of recurrent hemangiopericytomas...
  31. ncbi Radiosurgery for nonfunctioning pituitary adenoma
    Jason P Sheehan
    Department of Neurosurgical Surgery, University of Virginia Health Sciences Center, Charlottesville 22908, USA
    Neurosurg Focus 14:e9. 2003
    ..Nonfunctioning pituitary adenomas comprise approximately 30% of all pituitary tumors. The purpose of this retrospective study was to evaluate the efficacy and role of gamma knife surgery (GKS) in the treatment of these lesions...
  32. ncbi Gamma knife surgery for trigeminal neuralgia: outcomes and prognostic factors
    Jason Sheehan
    Lars Leksell Center for Gamma Surgery, Department of Neurological Surgery, University of Virginia Health System, Charlottesville, Virginia 22908, USA
    J Neurosurg 102:434-41. 2005
    ..Gamma knife surgery (GKS) has been used as an alternative, minimally invasive treatment in TN. In the present study, the authors evaluated the long-term results of GKS in the treatment of TN...
  33. ncbi Congenital absence of a cervical pedicle: report of two cases and review of the literature
    J Sheehan
    Department of Neurological Surgery, University of Virginia, Charlottesville, USA
    Neurosurgery 47:1439-42. 2000
    ..We report two cases of absent cervical pedicles and describe the presentation, diagnosis, and treatment of these patients. Moreover, we review the literature on this clinical entity...
  34. ncbi Pioneers in the development of neurological surgery in Auckland, New Zealand: Robertson, Wrightson, and Mackenzie
    Jason P Sheehan
    Department of Neurological Surgery, University of Virginia, Health Sciences Center, Charlottesville, Virginia 22908, USA
    Neurosurgery 57:364-8; discussion 364-8. 2005
    ..To demonstrate the development of neurosurgery in Auckland, New Zealand, which has diverse roots and was influenced by geographical, socioeconomic, and international forces...
  35. ncbi Intramedullary spinal cysticercosis. Case report and review of the literature
    Jason P Sheehan
    Department of Neurological Surgery, University of Virginia Health Sciences Center, Charlottesville, Virginia 22908, USA
    Neurosurg Focus 12:e10. 2002
    ..The authors present a case of isolated intramedullary cysticercosis of the cervical spine and review the literature...
  36. ncbi Stress fracture of the pedicle after extensive decompression and contralateral posterior fusion for lumbar stenosis. Report of three cases
    Jason P Sheehan
    Department of Neurological Surgery, University of Virginia Health Sciences Center, Charlottesville, Virginia 22908, USA
    Neurosurg Focus 13:E9. 2002
    ..Removal of the fractured pedicle, additional decompression, and enhanced bone fusion are recommended when the symptoms warrant surgical intervention...
  37. ncbi Development of a posterior fossa cavernous malformation associated with bilateral venous anomalies: case report
    Jason Sheehan
    Department of Neurological Surgery, Center for Image Guided Surgery, University of Pittsburgh Medical Center, Presbyterian Hospital, USA
    J Neuroimaging 12:371-3. 2002
    ..Furthermore, the detailed MRI permitted radiosurgical treatment of these CMs. The occurrence of de novo CMs adjacent to VAs on future imaging studies in other patients may help confirm the etiology of at least a subset of CMs...
  38. ncbi Stereotactic radiosurgery for pituitary adenomas: an intermediate review of its safety, efficacy, and role in the neurosurgical treatment armamentarium
    Jason P Sheehan
    Department of Neurological Surgery, University of Virginia Health System, Charlottesville, Virginia 22908, USA
    J Neurosurg 102:678-91. 2005
    ..More recently, radiosurgery has emerged as a viable treatment option. The goal of this research was to define more fully the efficacy, safety, and role of radiosurgery in the treatment of pituitary adenomas...
  39. ncbi A horseradish peroxidase-light and electron microscopic study of immunoliposomes utilized for intracellular delivery to the rat striatum
    J P Sheehan
    Department of Neurological Surgery, University of Virginia, Charlottesville, VA 22908, USA
    Neurosci Lett 333:212-6. 2002
    ..The research has helped to elucidate alternative mechanisms for immunoliposomal delivery. A more fundamental understanding of these attributes is needed to achieve the therapeutic potential of immunoliposomes...
  40. doi Gamma Knife surgery of meningiomas located in the posterior fossa: factors predictive of outcome and remission
    Robert M Starke
    Department of Neurological Surgery, University of Virginia, Charlottesville, Virginia 22908, USA
    J Neurosurg 114:1399-409. 2011
    ..In this study, the authors evaluate the outcomes of posterior fossa meningiomas treated with Gamma Knife surgery (GKS). The authors also assess factors predictive of new postoperative neurological deficits and tumor progression...
  41. doi Gamma Knife surgery for parasellar meningiomas: long-term results including complications, predictive factors, and progression-free survival
    Brian J Williams
    Department of Neurological Surgery, University of Virginia Health System, Charlottesville, Virginia 22908, USA
    J Neurosurg 114:1571-7. 2011
    ..This is particularly true for patients with parasellar meningiomas. In this study, the authors evaluated the outcomes of Gamma Knife surgery (GKS) used to treat parasellar meningiomas...
  42. doi Gamma Knife surgery for patients with nonfunctioning pituitary macroadenomas: predictors of tumor control, neurological deficits, and hypopituitarism
    Robert M Starke
    Department of Neurological Surgery, University of Virginia, Charlottesville, Virginia 22908, USA
    J Neurosurg 117:129-35. 2012
    ..In this study, the authors evaluated outcomes following GKS of nonfunctioning pituitary macroadenomas and assessed predictors of tumor control, neurological deficits, and delayed hypopituitarism...
  43. doi Gamma Knife radiosurgery to the surgical cavity following resection of brain metastases
    Jay Jagannathan
    Department of Neurological Surgery, University of Virginia Health Sciences Center, Charlottesville, VA 22908, USA
    J Neurosurg 111:431-8. 2009
    ..This study evaluated the efficacy of postoperative Gamma Knife surgery (GKS) to the tumor cavity following gross-total resection of a brain metastasis...
  44. doi Gamma Knife surgery for arteriovenous malformations in children
    Chun Po Yen
    Department of Neurological Surgery, University of Virginia Health System, Charlottesville, Virginia 22908, USA
    J Neurosurg Pediatr 6:426-34. 2010
    ..The aim of this study was to evaluate the long-term imaging and clinical outcomes of intracranial arteriovenous malformations (AVMs) in children treated with Gamma Knife surgery (GKS)...
  45. doi Clinical and pathological characteristics of brain metastasis resected after failed radiosurgery
    Jay Jagannathan
    Department of Neurosurgery, University of Virginia Health Sciences Center, Box 800212, Charlottesville, VA 22902, USA
    Neurosurgery 66:208-17. 2010
    ..This study evaluates the tumor histopathology and clinical characteristics of patients who underwent resection of their brain metastasis after failed gamma knife radiosurgery...
  46. doi Transcranial magnetic resonance-guided focused ultrasound surgery for trigeminal neuralgia: a cadaveric and laboratory feasibility study
    Stephen J Monteith
    Department of Neurosurgery, University of Virginia Health System, Charlottesville, Virginia 22908, USA
    J Neurosurg 118:319-28. 2013
    ..In this study, the authors explore the feasibility of targeting the trigeminal nerve in a cadaveric model with temperature assessments using computer simulations and an in vitro skull phantom model fitted with thermocouples...
  47. doi Cranial nerve dysfunction following Gamma Knife surgery for pituitary adenomas: long-term incidence and risk factors
    Christopher P Cifarelli
    Department of Neurological Surgery, University of Virginia Health System, Charlottesville, Virginia 22908 0212, USA
    J Neurosurg 116:1304-10. 2012
    ..This study evaluates the long-term risks of ophthalmological dysfunction following GKS for recurrent pituitary adenomas...
  48. ncbi Cerebellar mutism in adults after posterior fossa surgery: a report of 2 cases
    Jonathan H Sherman
    Department of Neurological Surgery, University of Virginia, Charlottesville, VA 22908, USA
    Surg Neurol 63:476-9. 2005
    ..Characteristics of CMS include complete absence of speech without impaired consciousness, other cranial nerve deficits, or long tract signs...
  49. doi Radiation dose and incidence of new metastasis in the anterior temporal lobe structures of radiosurgically treated patients
    Bhuvaneswara R Basina
    Department of Neurological Surgery, University of Virginia Health System, Charlottesville, Virginia 22908 0212, USA
    J Neurosurg 112:122-9. 2010
    ..They also evaluated the incidence and timing of new metastases in the anterior temporal lobes (ATLs) in patient cohorts that underwent GKS with or without whole-brain radiation therapy (WBRT)...
  50. ncbi Gamma Knife surgery for Cushing's disease
    Jay Jagannathan
    Department of Neurological Surgery, University of Virginia Health System, Charlottesville, Virginia 22908 00212, USA
    J Neurosurg 106:980-7. 2007
    ..In this study the authors address the efficacy and safety of Gamma Knife surgery (GKS) in patients with adrenocorticotropic hormone-secreting pituitary adenomas...
  51. doi Evaluation of the role of Gamma Knife surgery in the treatment of craniopharyngiomas
    Rupa Gopalan
    Department of Neurological Surgery, University of Virginia Health System, Charlottesville, Virginia 22908, USA
    Neurosurg Focus 24:E5. 2008
    ..The overall morbidity rate resulting from radiosurgery was 4% and the overall mortality rate was 0.5%. These results suggest that GKS may provide a favorable benefit-to-risk profile for many patients with craniopharyngiomas...
  52. ncbi Initial Gamma Knife radiosurgery for nonfunctioning pituitary adenomas
    Cheng Chia Lee
    Department of Neurological Surgery, University of Virginia Health System, Charlottesville, Virginia
    J Neurosurg 120:647-54. 2014
    ..In this report, the authors evaluated the efficacy and safety of initial GKRS for NFAs...
  53. ncbi Anterior stabilization of three-column thoracolumbar spinal trauma
    Rod J Oskouian
    Department of Neurological and Orthopaedic Surgery, University of Virginia Health System, Charlottesville, Virginia 22902, USA
    J Neurosurg Spine 5:18-25. 2006
    ..The purpose of this study was to evaluate the results obtained in patients who underwent anterior stabilization for three-column thoracolumbar fractures...
  54. doi Radiosurgery for patients with unruptured intracranial arteriovenous malformations
    Dale Ding
    Department of Neurological Surgery, University of Virginia Health System, Charlottesville, Virginia 22908, USA
    J Neurosurg 118:958-66. 2013
    ..In the present study, the authors evaluate the radiographic and clinical outcomes of radiosurgery for a large cohort of patients with unruptured AVMs...
  55. doi Gamma Knife surgery for basal ganglia and thalamic arteriovenous malformations
    Ching Hsiao Cheng
    Department of Neurological Surgery, University of Virginia Health System, Charlottesville, VA, USA
    J Neurosurg 116:899-908. 2012
    ..The present study aims to investigate the outcomes of GKS for AVMs in the basal ganglia and thalamus...
  56. doi Gamma Knife radiosurgery after radiation therapy as an adjunctive treatment for glioblastoma
    Nader Pouratian
    Department of Neurological Surgery, University of Virginia, Charlottesville, VA 22908, USA
    J Neurooncol 94:409-18. 2009
    ..Moreover, SRS may be a viable alternative to open surgery for aggressive management of GBM at the time of recurrence. Prospective studies of SRS for GBM should focus on these two groups of patients...
  57. ncbi Benign brain tumors: sellar/parasellar tumors
    Jay Jagannathan
    Department of Neurosurgery, University of Virginia Health System, PO Box 800212, Charlottesville, VA 22908 0711, USA
    Neurol Clin 25:1231-49, xi. 2007
    ..Less invasive modalities, such as endoscopic transsphenoidal surgery, specific chemotherapeutic drugs, and stereotactic radiosurgery, show promise as adjuvant treatment modalities...
  58. ncbi Bevacizumab for refractory adverse radiation effects after stereotactic radiosurgery
    Christopher P Deibert
    Department of Neurological Surgery, University of Pittsburgh Medical Center, 200 Lothrop Street, Suite B 400, Pittsburgh, PA, 15213, USA
    J Neurooncol 115:217-23. 2013
    ..The necessary duration and optimum dose of therapy is unknown and provides a further impetus to conduct a prospective trial...
  59. doi Radiosurgery in the treatment of spinal metastases: tumor control, survival, and quality of life after helical tomotherapy
    Jason P Sheehan
    Departments of Neurological Surgery and Radiation Oncology, University of Virginia Health Sciences Center, Charlottesville, Virginia 22908, USA
    Neurosurgery 65:1052-61; discussion 1061-2. 2009
    ..The effectiveness and limitations of spinal radiosurgery using a helical TomoTherapy system for the treatment of spinal metastases are reviewed in this article...
  60. doi Intracranial plasmacytoma with apoplectic presentation and spontaneous intracerebral hemorrhage: Case report and review of the literature
    R Webster Crowley
    Department of Neurological Surgery, University of Virginia School of Medicine, Charlottesville, 22908, United States
    Clin Neurol Neurosurg 112:172-5. 2010
    ..The onset of new symptoms referable to potential intracranial pathology in this setting should prompt consideration of intracranial plasmacytoma in the differential diagnosis...
  61. ncbi Applications of radiotherapy and radiosurgery in the management of pediatric Cushing's disease: a review of the literature and our experience
    Jay Jagannathan
    Department of Neurological Surgery, University of Virginia Health Sciences Center, University of Virginia, Charlottesville, VA 22908, USA
    J Neurooncol 90:117-24. 2008
    ..This paper reviews the effectiveness of radiation in the treatment of pediatric Cushing's disease...
  62. doi Gamma knife radiosurgery for acromegaly: outcomes after failed transsphenoidal surgery
    Jay Jagannathan
    Lars Leksell Gamma Knife Center, Department of Neurosurgery, University of Virginia Health Sciences Center, Charlottesville, Virginia, USA
    Neurosurgery 62:1262-9; discussion 1269-70. 2008
    ..This study evaluates the safety and efficacy of gamma knife radiosurgery (GKRS) in patients with a growth hormone-secreting adenoma...
  63. doi Gamma knife surgery for lymphocytic hypophysitis
    Dibyendu Kumar Ray
    Department of Neurological Surgery, University of Virginia, Charlottesville, Virginia, USA
    J Neurosurg 112:118-21. 2010
    ..Follow-up MR images demonstrated no evidence of recurrence of lymphocytic hypophysitis. For persistent lymphocytic hypophysitis, GKS is a reasonable treatment option...
  64. doi Initial experience with the eXtend System: a relocatable frame system for multiple-session gamma knife radiosurgery
    Faisal T Sayer
    Department of Neurological Surgery, University of Virginia, Charlottesville, Virginia, USA
    World Neurosurg 75:665-72. 2011
    ..To present our initial experience with the Elekta eXtend System, a relocatable frame system for multiple-fraction or serial multiple-session radiosurgery...
  65. doi Bevacizumab used for the treatment of severe, refractory perilesional edema due to an arteriovenous malformation treated with stereotactic radiosurgery
    Brian J Williams
    Department of Neurological Surgery, University of Virginia Health System, Charlottesville, Virginia 22908, USA
    J Neurosurg 116:972-7. 2012
    ..This is the first time that bevacizumab has been used to control severe refractory perilesional edema related to an intracranial arteriovenous malformation...
  66. doi Gamma knife surgery for skull base meningiomas
    Robert M Starke
    Department of Neurological Surgery, University of Virginia Health System, Charlottesville, Virginia 22908, USA
    J Neurosurg 116:588-97. 2012
    ..In this study, the authors evaluate the outcomes of skull base meningiomas treated with Gamma Knife surgery (GKS) both as an adjunct to microsurgery and as a primary treatment modality...
  67. doi Stereotactic radiosurgery for pituitary adenomas: a comprehensive review of indications, techniques and long-term results using the Gamma Knife
    Jay Jagannathan
    Department of Neurological Surgery, University of Virginia Health Sciences Center, Box 800212, Charlottesville, VA 22908, USA
    J Neurooncol 92:345-56. 2009
    ..This study reviews the long-term clinical results of stereotactic radiosurgery in the treatment of pituitary adenoma patients...
  68. doi Gamma knife radiosurgery for intracranial hemangioblastomas--outcome at 3 years
    Faisal T Sayer
    Department of Neurological Surgery, University of Virginia, Charlottesville, Virginia, USA
    World Neurosurg 75:99-105; discussion 45-8. 2011
    ..To define the role of Gamma Knife radiosurgery (GKRS) for the treatment of patients with hemangioblastomas...
  69. doi Early brain tumor metastasis reduction following Gamma Knife surgery
    Arnaldo Neves Da Silva
    The Lars Leksell Gamma Knife Center, Department of Neurosurgery, University of Virginia Health System, Charlottesville, Virginia 22908, USA
    J Neurosurg 110:547-52. 2009
    ..Unlike whole-brain radiation therapy, Gamma Knife surgery (GKS) is delivered in a single session for the treatment of brain metastases. The extent to which GKS can facilitate early tumor control was the focus of this study...
  70. ncbi Gamma Knife surgery for adrenocorticotropic hormone-producing pituitary adenomas after bilateral adrenalectomy
    William J Mauermann
    Lars Leksell Gamma Knife Center, University of Virginia Health System, Charlottesville, Virginia, USA
    J Neurosurg 106:988-93. 2007
    ..These patients with Nelson's syndrome can be treated with Gamma Knife surgery (GKS)...
  71. pmc Tracking brain motion during the cardiac cycle using spiral cine-DENSE MRI
    Xiaodong Zhong
    Department of Biomedical Engineering, University of Virginia, Charlottesville, Virginia 22908, USA
    Med Phys 36:3413-9. 2009
    ..These preliminary results demonstrated that the spiral cine-DENSE MRI technique can be used to measure cardiac-synchronized pulsatile brain motion on the pixel-by-pixel basis with high temporal/spatial resolution and sensitivity...
  72. doi Radiation therapy and stereotactic radiosurgery for the treatment of Cushing's disease: an evidence-based review
    Robert M Starke
    Department of Neurological Surgery, University of Virginia, Charlottesville, Virginia 22908, USA
    Curr Opin Endocrinol Diabetes Obes 17:356-64. 2010
    ..g. maximal dose, tumor margin dose), length of follow-up, tumor-control rate, complications, rate of hormone normalization, newly onset loss of pituitary function, and method used to assess endocrine remission...
  73. ncbi Leksell GammaPlan version 10.0 preview: performance of the new inverse treatment planning algorithm applied to Gamma Knife surgery for pituitary adenoma
    David J Schlesinger
    Department of Neurological Surgery, University of Virginia Health System, Charlottesville, Virginia 22908, USA
    J Neurosurg 113:144-8. 2010
    ..In this study the authors compared the FP and IP approaches to Gamma Knife surgery...
  74. ncbi Single-center experience with pediatric Cushing's disease
    Adam S Kanter
    Department of Neurological Surgery, University of Virginia Health System, Charlottesville, Virginia 22908, USA
    J Neurosurg 103:413-20. 2005
    ....
  75. doi Gamma knife radiosurgery for brain metastasis of nonsmall cell lung cancer: is there a difference in outcome between morning and afternoon treatment?
    Douglas A Rahn
    Department of Radiation Oncology, University of Virginia Health Sciences Center, Charlottesville, Virginia 22908, USA
    Cancer 117:414-20. 2011
    ..The purpose of this study was to determine whether outcomes of single-session gamma knife radiosurgery (GKRS) for metastatic nonsmall cell lung cancer (NSCLC) differ based on treatment time...
  76. ncbi High-intensity focused ultrasound surgery of the brain: part 1--A historical perspective with modern applications
    Jay Jagannathan
    Department of Neurological Surgery, University of Virginia Health Sciences Center, Charlottesville, Virginia 22902, USA
    Neurosurgery 64:201-10; discussion 210-1. 2009
    ..The remaining 2 articles in this series will focus on the physical principles of modern MRgFUS as well as current and future avenues for investigation...
  77. doi Treatment of glomus jugulare tumors with gamma knife radiosurgery
    Philip G Chen
    Department of Otolaryngology, Head and Neck Surgery, University of Virginia, Charlottesville, Virginia, USA
    Laryngoscope 120:1856-62. 2010
    ..However, the optimal treatment of these tumors remains unclear. The authors report their data on treatment of GJTs with gamma knife radiosurgery (GKS)...
  78. doi Impact of the Accreditation Council for Graduate Medical Education work-hour regulations on neurosurgical resident education and productivity
    Jay Jagannathan
    Departments of Neurological Surgery, University of Virginia Health Sciences Center, Charlottesville, Virginia, USA
    J Neurosurg 110:820-7. 2009
    ..The authors have evaluated multiple objective surrogate markers of resident performance and quality of training to determine the impact of the 80-hour workweek...
  79. doi Treatment of intracranial solitary fibrous tumors with gamma knife radiosurgery: report of two cases and review of literature
    Davis L Reames
    Department of Neurosurgery, University of Virginia Health System, Charlottesville, VA, USA
    Neurosurgery 69:E1023-8; discussion E1028. 2011
    ..Gamma knife radiosurgery (GKRS) as a treatment option has not been described in the management of typical intracranial solitary fibrous tumors...
  80. doi Hemorrhage risk of cerebral arteriovenous malformations before and during the latency period after GAMMA knife radiosurgery
    Chun Po Yen
    Lars Leksell Center for Gamma Surgery, Department of Neurological Surgery, University of Virginia Health Sciences System, 1215 Lee Street, Room G512, Charlottesville, VA 22908, USA
    Stroke 42:1691-6. 2011
    ..To evaluate the hemorrhage rates of cerebral arteriovenous malformations (AVM) and the risk factors of hemorrhage before and after Gamma Knife radiosurgery (GKS)...
  81. ncbi Evaluation and management of Cushing syndrome in cases of negative sellar magnetic resonance imaging
    Jay Jagannathan
    Department of Neurosurgery, University of Virginia Health Sciences Center, University of Virginia, Charlottesville, Virginia 22908, USA
    Neurosurg Focus 23:E3. 2007
    ..Radiosurgery is an effective treatment option in patients with persistent Cushing disease. When a target cannot be found on MR imaging, one can target the entire sellar region with radiosurgery...
  82. ncbi Follicular lymphoma of the dura: case report
    D Kojo Hamilton
    Department of Neurological Surgery, University of Virginia, Charlottesville 22908, USA
    Neurosurgery 59:E703-4; discussion E703-4. 2006
    ..The case illustrates the clinical, radiological, and histological relevance of this rare entity...
  83. ncbi Stereotactic radiosurgery for pituitary adenomas: a review of the literature
    Edward R Laws
    University of Virginia, Charlottesville, VA 22908, USA
    J Neurooncol 69:257-72. 2004
    ..More recently, radiosurgery has emerged as a viable treatment option. The goal of this research is to define accurately the efficacy, safety, and role of radiosurgery for treatment of pituitary adenomas...
  84. ncbi Gamma knife surgery for low-grade gliomas
    Peter A Heppner
    The Lars Leksell Gamma Knife Center, Department of Neurological Surgery, University of Virginia, Charlottesville, Virginia, USA
    Neurosurgery 57:1132-9; discussion. 2005
    ..We aimed to review the outcome of patients with low-grade gliomas undergoing Gamma knife surgery at the Lars Leksell Gamma Knife Center at the University of Virginia to clarify its role in the management of these lesions...
  85. ncbi Evaluation of thoracic spinal cord motion using dynamic MRI
    Jing Cai
    Department of Radiation Oncology, University of Virginia, Charlottesville, VA 22908, USA
    Radiother Oncol 84:279-82. 2007
    ..We found that the mean motion range at different thoracic levels is typically within 0.5mm. The good stability makes this an excellent position for stereotactic radiotherapy (SBRT)...
  86. doi Gamma Knife surgery for brain metastases from gastrointestinal cancer
    Arnaldo Neves Da Silva
    The Lars Leksell Gamma Knife Center, Department of Neurological Surgery, University of Virginia Health System, Charlottesville, Virginia 22908, USA
    J Neurosurg 111:423-30. 2009
    ..The purpose of this study was to evaluate the efficacy of Gamma Knife surgery (GKS) for the treatment of brain metastases from gastrointestinal cancers...
  87. pmc Microarray analysis of gene expression in mouse aorta reveals role of the calcium signaling pathway in control of atherosclerosis susceptibility
    Zuobiao Yuan
    Department of Radiology, Univ of Virginia, Box 801339, Snyder Bldg 266, 480 Ray C Hunt Dr, Fontaine Research Park, Charlottesville, VA 22908, USA
    Am J Physiol Heart Circ Physiol 296:H1336-43. 2009
    ..The present findings demonstrate involvement of the calcium signaling pathway in the inflammatory process of atherogenesis...
  88. ncbi Current concepts in management of meningiomas and schwannomas
    Ashok R Asthagiri
    National Institutes of Health NINDS, Bethesda, MD, USA
    Neurol Clin 25:1209-30, xi. 2007
    ..The goal of this article is to provide a review of the current literature surrounding the mainstays of therapy for these lesions...
  89. ncbi Linear accelerator radiosurgery for vestibular schwannomas
    Jason P Sheehan
    J Neurosurg 105:655-6; discussion 656. 2006