Shivani Sharma

Summary

Affiliation: University of California
Country: USA

Publications

  1. pmc Correlative nanoscale imaging of actin filaments and their complexes
    Shivani Sharma
    Department of Chemistry and Biochemistry, University of California, Los Angeles, California, USA
    Nanoscale 5:5692-702. 2013
  2. pmc Molecular cooperativity of drebrin1-300 binding and structural remodeling of F-actin
    Shivani Sharma
    Department of Chemistry, University of California, Los Angeles, California, USA
    Biophys J 103:275-83. 2012
  3. doi request reprint Correlative nanomechanical profiling with super-resolution F-actin imaging reveals novel insights into mechanisms of cisplatin resistance in ovarian cancer cells
    Shivani Sharma
    Department of Chemistry and Biochemistry, University of California, Los Angeles, California 90095, USA
    Nanomedicine 8:757-66. 2012
  4. pmc Nanocharacterization in dentistry
    Shivani Sharma
    Department of Chemistry and Biochemistry, University of California, Los Angeles 90095, CA, USA E Mails S S S E C C H R P W
    Int J Mol Sci 11:2523-45. 2010
  5. pmc Atomic force microscopy reveals drebrin induced remodeling of f-actin with subnanometer resolution
    Shivani Sharma
    Department of Chemistry and Biochemistry, University of California, Los Angeles, California 90095, USA
    Nano Lett 11:825-7. 2011
  6. pmc Quantitative nanostructural and single-molecule force spectroscopy biomolecular analysis of human-saliva-derived exosomes
    Shivani Sharma
    Department of Chemistry and Biochemistry and California NanoSystems Institute, University of California, Los Angeles, California 90095, USA
    Langmuir 27:14394-400. 2011
  7. pmc Nanostructured Self-Assembly of Inverted Formin 2 (INF2) and F-Actin-INF2 Complexes Revealed by Atomic Force Microscopy
    Shivani Sharma
    Department of Chemistry and Biochemistry, University of California, Los Angeles, California 90095, United States
    Langmuir 30:7533-9. 2014
  8. ncbi request reprint The role of Rho GTPase in cell stiffness and cisplatin resistance in ovarian cancer cells
    Shivani Sharma
    Department of Chemistry and Biochemistry, University of California, Los Angeles, California, USA
    Integr Biol (Camb) 6:611-7. 2014
  9. pmc Structural-mechanical characterization of nanoparticle exosomes in human saliva, using correlative AFM, FESEM, and force spectroscopy
    Shivani Sharma
    Department of Chemistry and Biochemistry, University of California, Los Angeles, California 90095, USA
    ACS Nano 4:1921-6. 2010
  10. ncbi request reprint Nanoscale characterization of effect of l-arginine on Streptococcus mutans biofilm adhesion by atomic force microscopy
    Shivani Sharma
    Department of Chemistry and Biochemistry, University of California, Los Angeles, CA, USA California NanoSystems Institute, University of California, Los Angeles, CA, USA
    Microbiology 160:1466-73. 2014

Detail Information

Publications12

  1. pmc Correlative nanoscale imaging of actin filaments and their complexes
    Shivani Sharma
    Department of Chemistry and Biochemistry, University of California, Los Angeles, California, USA
    Nanoscale 5:5692-702. 2013
    ....
  2. pmc Molecular cooperativity of drebrin1-300 binding and structural remodeling of F-actin
    Shivani Sharma
    Department of Chemistry, University of California, Los Angeles, California, USA
    Biophys J 103:275-83. 2012
    ..The data confirm at the in vitro molecular level that variations in the F-actin helical structure can be modulated by cooperative binding of actin-binding proteins...
  3. doi request reprint Correlative nanomechanical profiling with super-resolution F-actin imaging reveals novel insights into mechanisms of cisplatin resistance in ovarian cancer cells
    Shivani Sharma
    Department of Chemistry and Biochemistry, University of California, Los Angeles, California 90095, USA
    Nanomedicine 8:757-66. 2012
    ..These findings reveal a direct role of the actin remodeling mechanism in cisplatin resistance of ovarian cancer cells, suggesting potential future applications of nanomechanical profiling as a marker for cancer drug sensitivity...
  4. pmc Nanocharacterization in dentistry
    Shivani Sharma
    Department of Chemistry and Biochemistry, University of California, Los Angeles 90095, CA, USA E Mails S S S E C C H R P W
    Int J Mol Sci 11:2523-45. 2010
    ..An outlook on future "nanodentistry" developments such as saliva exosomes based diagnostics, designing biocompatible, antimicrobial dental implants and personalized dental healthcare is presented...
  5. pmc Atomic force microscopy reveals drebrin induced remodeling of f-actin with subnanometer resolution
    Shivani Sharma
    Department of Chemistry and Biochemistry, University of California, Los Angeles, California 90095, USA
    Nano Lett 11:825-7. 2011
    ....
  6. pmc Quantitative nanostructural and single-molecule force spectroscopy biomolecular analysis of human-saliva-derived exosomes
    Shivani Sharma
    Department of Chemistry and Biochemistry and California NanoSystems Institute, University of California, Los Angeles, California 90095, USA
    Langmuir 27:14394-400. 2011
    ..We discuss the use of quantitative, nanoscale ultrastructural and surface biomolecular analysis of saliva exosomes at single-vesicle- and single-protein-level sensitivities as a potentially new oral cancer diagnostic...
  7. pmc Nanostructured Self-Assembly of Inverted Formin 2 (INF2) and F-Actin-INF2 Complexes Revealed by Atomic Force Microscopy
    Shivani Sharma
    Department of Chemistry and Biochemistry, University of California, Los Angeles, California 90095, United States
    Langmuir 30:7533-9. 2014
    ....
  8. ncbi request reprint The role of Rho GTPase in cell stiffness and cisplatin resistance in ovarian cancer cells
    Shivani Sharma
    Department of Chemistry and Biochemistry, University of California, Los Angeles, California, USA
    Integr Biol (Camb) 6:611-7. 2014
    ..These findings suggest the potential applicability of cell mechanical phenotyping as a model for determining sensitivity of ovarian cancer cells that could have major implications in ovarian cancer diagnosis and personalized medicine. ..
  9. pmc Structural-mechanical characterization of nanoparticle exosomes in human saliva, using correlative AFM, FESEM, and force spectroscopy
    Shivani Sharma
    Department of Chemistry and Biochemistry, University of California, Los Angeles, California 90095, USA
    ACS Nano 4:1921-6. 2010
    ....
  10. ncbi request reprint Nanoscale characterization of effect of l-arginine on Streptococcus mutans biofilm adhesion by atomic force microscopy
    Shivani Sharma
    Department of Chemistry and Biochemistry, University of California, Los Angeles, CA, USA California NanoSystems Institute, University of California, Los Angeles, CA, USA
    Microbiology 160:1466-73. 2014
    ..Our results suggest that the presence of Arg in the oral cavity could influence the adhesion properties of S. mutans to the tooth surface. ..
  11. pmc Nanofilaments on glioblastoma exosomes revealed by peak force microscopy
    Shivani Sharma
    Department of Chemistry and Biochemistry, University of California, Los Angeles, CA 90095, USA
    J R Soc Interface 11:20131150. 2014
    ..These stiff, adhesive, trypsin- and RNAse-resistant surface nanofilaments add a new dimension to the current structural knowledge of exosome-mediated intercellular communication. ..
  12. pmc DNA builds and strengthens the extracellular matrix in Myxococcus xanthus biofilms by interacting with exopolysaccharides
    Wei Hu
    State Key Laboratory of Microbial Technology, School of Life Science, Shandong University, Jinan, Shandong, China
    PLoS ONE 7:e51905. 2012
    ..Taken together, these findings demonstrate that DNA interacts with EPS and strengthens biofilm structures in M. xanthus...