Janhavi Sharma

Summary

Affiliation: University of California
Country: USA

Publications

  1. pmc The absence of myocardial calcium-independent phospholipase A2γ results in impaired prostaglandin E2 production and decreased survival in mice with acute Trypanosoma cruzi infection
    Janhavi Sharma
    Department of Pathology, Saint Louis University School of Medicine, St Louis, Missouri, USA
    Infect Immun 81:2278-87. 2013
  2. pmc Lung endothelial cell platelet-activating factor production and inflammatory cell adherence are increased in response to cigarette smoke component exposure
    Janhavi Sharma
    Department of Pathology, Saint Louis University School of Medicine, St Louis, Missouri 63104, USA
    Am J Physiol Lung Cell Mol Physiol 302:L47-55. 2012
  3. pmc Activation of group VI phospholipase A2 isoforms in cardiac endothelial cells
    Janhavi Sharma
    Department of Pathology, Saint Louis University School of Medicine, Missouri, USA
    Am J Physiol Cell Physiol 300:C872-9. 2011
  4. pmc Platelet-activating factor and metastasis: calcium-independent phospholipase A2β deficiency protects against breast cancer metastasis to the lung
    Jane McHowat
    Department of Pathology, Saint Louis University School of Medicine, Missouri 63104, USA
    Am J Physiol Cell Physiol 300:C825-32. 2011
  5. doi request reprint PGE2 release from tryptase-stimulated rabbit ventricular myocytes is mediated by calcium-independent phospholipase A2γ
    Janhavi Sharma
    Department of Pathology, Saint Louis University School of Medicine, 1402 S Grand Blvd, St Louis, MO 63104, USA
    Lipids 46:391-7. 2011
  6. pmc Endothelial cell prostaglandin I(2) and platelet-activating factor production are markedly attenuated in the calcium-independent phospholipase A(2)beta knockout mouse
    Janhavi Sharma
    Department of Pathology, Saint Louis University School of Medicine, St Louis, Missouri 63104, USA
    Biochemistry 49:5473-81. 2010
  7. pmc Polymorphonuclear leukocytes isolated from umbilical cord blood as a useful research tool to study adherence to cell monolayers
    Janhavi Sharma
    Department of Pathology, Saint Louis University School of Medicine, 1402 S Grand Blvd, St Louis, Missouri 63104, USA
    J Immunol Methods 351:30-5. 2009

Detail Information

Publications7

  1. pmc The absence of myocardial calcium-independent phospholipase A2γ results in impaired prostaglandin E2 production and decreased survival in mice with acute Trypanosoma cruzi infection
    Janhavi Sharma
    Department of Pathology, Saint Louis University School of Medicine, St Louis, Missouri, USA
    Infect Immun 81:2278-87. 2013
    ..Thus, these studies suggest that iPLA2γ plays a cardioprotective role during the acute stage of Chagas' disease...
  2. pmc Lung endothelial cell platelet-activating factor production and inflammatory cell adherence are increased in response to cigarette smoke component exposure
    Janhavi Sharma
    Department of Pathology, Saint Louis University School of Medicine, St Louis, Missouri 63104, USA
    Am J Physiol Lung Cell Mol Physiol 302:L47-55. 2012
    ..In addition, iPLA(2)β is identified as a potential target for therapeutic interventions to reduce airway inflammation and the progression of chronic lung disease...
  3. pmc Activation of group VI phospholipase A2 isoforms in cardiac endothelial cells
    Janhavi Sharma
    Department of Pathology, Saint Louis University School of Medicine, Missouri, USA
    Am J Physiol Cell Physiol 300:C872-9. 2011
    ..These results indicate that cardiac endothelial cell PAF production is dependent on iPLA(2)β activation and that both iPLA(2)β and iPLA(2)γ may be involved in PGI(2) release...
  4. pmc Platelet-activating factor and metastasis: calcium-independent phospholipase A2β deficiency protects against breast cancer metastasis to the lung
    Jane McHowat
    Department of Pathology, Saint Louis University School of Medicine, Missouri 63104, USA
    Am J Physiol Cell Physiol 300:C825-32. 2011
    ..These data indicate that endothelial cell iPLA(2)β is responsible for PAF production and adherence of E0771 cells and may play a role in cancer cell migration to distal locations...
  5. doi request reprint PGE2 release from tryptase-stimulated rabbit ventricular myocytes is mediated by calcium-independent phospholipase A2γ
    Janhavi Sharma
    Department of Pathology, Saint Louis University School of Medicine, 1402 S Grand Blvd, St Louis, MO 63104, USA
    Lipids 46:391-7. 2011
    ..These studies demonstrate that PGE(2) release from tryptase stimulated rabbit ventricular myocytes is mediated primarily by iPLA(2)γ...
  6. pmc Endothelial cell prostaglandin I(2) and platelet-activating factor production are markedly attenuated in the calcium-independent phospholipase A(2)beta knockout mouse
    Janhavi Sharma
    Department of Pathology, Saint Louis University School of Medicine, St Louis, Missouri 63104, USA
    Biochemistry 49:5473-81. 2010
    ....
  7. pmc Polymorphonuclear leukocytes isolated from umbilical cord blood as a useful research tool to study adherence to cell monolayers
    Janhavi Sharma
    Department of Pathology, Saint Louis University School of Medicine, 1402 S Grand Blvd, St Louis, Missouri 63104, USA
    J Immunol Methods 351:30-5. 2009
    ..In conclusion, our data suggest that umbilical cord blood is a suitable source of leukocytes to examine PMN adherence in the setting of inflammation in a variety of disease processes...