Shahrokh F Shariat

Summary

Affiliation: University of Texas Southwestern Medical Center
Country: USA

Publications

  1. ncbi Survivin expression is associated with bladder cancer presence, stage, progression, and mortality
    Shahrokh F Shariat
    Department of Urology, University of Texas Southwestern Medical Center at Dallas, Texas 75390 9110, USA
    Cancer 109:1106-13. 2007
  2. ncbi Notice of duplicate publication: "Potentially harmful effect of a testosterone dietary supplement on prostate cancer growth and metastasis" (arch intern med. 2008;168[2]:235-236)
    Shahrokh F Shariat
    Department of Urology, The University of Texas Southwestern Medical Center, 5323 Harry Hines Blvd, Dallas, TX 75390-9110
    Arch Intern Med 168:2046-7. 2008
  3. ncbi Preoperative plasma HER2 and epidermal growth factor receptor for staging and prognostication in patients with clinically localized prostate cancer
    Shahrokh F Shariat
    Department of Urology, University of Texas Southwestern Medical Center at Dallas, Dallas, Texas 75390 9110, USA
    Clin Cancer Res 13:5377-84. 2007
  4. ncbi Inventory of prostate cancer predictive tools
    Shahrokh F Shariat
    Department of Urology, University of Texas Southwestern Medical Centre, Dallas, Texas 75390 9110, USA
    Curr Opin Urol 18:279-96. 2008
  5. ncbi Features and outcomes of patients with grade IV renal injury
    Shahrokh F Shariat
    Department of Urology, University of Texas Southwestern Medical Center, Dallas, TX 75390 9110, USA
    BJU Int 102:728-33; discussion 733. 2008
  6. ncbi Development of a highly accurate nomogram for prediction of the need for exploration in patients with renal trauma
    Shahrokh F Shariat
    Department of Urology, University of Texas Southwestern Medical Center, Dallas, Texas, USA
    J Trauma 64:1451-8. 2008
  7. ncbi Predictive value of cell cycle biomarkers in nonmuscle invasive bladder transitional cell carcinoma
    Shahrokh F Shariat
    Department of Urology, University of Texas Southwestern Medical Center, Dallas, Texas 75390 9110, USA
    J Urol 177:481-7; discussion 487. 2007
  8. ncbi Outcomes of radical cystectomy for transitional cell carcinoma of the bladder: a contemporary series from the Bladder Cancer Research Consortium
    Shahrokh F Shariat
    Department of Urology, University of Texas Southwestern Medical Center, 5323 Harry Hines Boulevard, Dallas, TX 75390, USA
    J Urol 176:2414-22; discussion 2422. 2006
  9. ncbi Concomitant carcinoma in situ is a feature of aggressive disease in patients with organ-confined TCC at radical cystectomy
    Shahrokh F Shariat
    Department of Urology, University of Texas Southwestern Medical Center, Dallas, TX 75390 9110, USA
    Eur Urol 51:152-60. 2007
  10. ncbi Association of the circulating levels of the urokinase system of plasminogen activation with the presence of prostate cancer and invasion, progression, and metastasis
    Shahrokh F Shariat
    Department of Urology, The University of Texas Southwestern Medical Center, Dallas, TX 75390 9110, USA
    J Clin Oncol 25:349-55. 2007

Collaborators

Detail Information

Publications109 found, 100 shown here

  1. ncbi Survivin expression is associated with bladder cancer presence, stage, progression, and mortality
    Shahrokh F Shariat
    Department of Urology, University of Texas Southwestern Medical Center at Dallas, Texas 75390 9110, USA
    Cancer 109:1106-13. 2007
    ....
  2. ncbi Notice of duplicate publication: "Potentially harmful effect of a testosterone dietary supplement on prostate cancer growth and metastasis" (arch intern med. 2008;168[2]:235-236)
    Shahrokh F Shariat
    Department of Urology, The University of Texas Southwestern Medical Center, 5323 Harry Hines Blvd, Dallas, TX 75390-9110
    Arch Intern Med 168:2046-7. 2008
  3. ncbi Preoperative plasma HER2 and epidermal growth factor receptor for staging and prognostication in patients with clinically localized prostate cancer
    Shahrokh F Shariat
    Department of Urology, University of Texas Southwestern Medical Center at Dallas, Dallas, Texas 75390 9110, USA
    Clin Cancer Res 13:5377-84. 2007
    ..We tested the hypothesis that plasma levels of HER2 and/or EGFR are associated with prostate cancer stage and prognosis in patients with clinically localized disease...
  4. ncbi Inventory of prostate cancer predictive tools
    Shahrokh F Shariat
    Department of Urology, University of Texas Southwestern Medical Centre, Dallas, Texas 75390 9110, USA
    Curr Opin Urol 18:279-96. 2008
    ..We describe the patient populations to which they apply and the outcomes predicted, and record their individual characteristics...
  5. ncbi Features and outcomes of patients with grade IV renal injury
    Shahrokh F Shariat
    Department of Urology, University of Texas Southwestern Medical Center, Dallas, TX 75390 9110, USA
    BJU Int 102:728-33; discussion 733. 2008
    ....
  6. ncbi Development of a highly accurate nomogram for prediction of the need for exploration in patients with renal trauma
    Shahrokh F Shariat
    Department of Urology, University of Texas Southwestern Medical Center, Dallas, Texas, USA
    J Trauma 64:1451-8. 2008
    ..To develop and validate a nomogram for predicting the need for renal exploration after renal trauma...
  7. ncbi Predictive value of cell cycle biomarkers in nonmuscle invasive bladder transitional cell carcinoma
    Shahrokh F Shariat
    Department of Urology, University of Texas Southwestern Medical Center, Dallas, Texas 75390 9110, USA
    J Urol 177:481-7; discussion 487. 2007
    ..We determined whether the combined expression of p53, p21, p27 and pRB is associated with outcomes of patients with nonmuscle invasive bladder transitional cell carcinoma...
  8. ncbi Outcomes of radical cystectomy for transitional cell carcinoma of the bladder: a contemporary series from the Bladder Cancer Research Consortium
    Shahrokh F Shariat
    Department of Urology, University of Texas Southwestern Medical Center, 5323 Harry Hines Boulevard, Dallas, TX 75390, USA
    J Urol 176:2414-22; discussion 2422. 2006
    ..We present the characteristics and outcomes of a large, contemporary, consecutive series of patients treated with radical cystectomy and pelvic lymphadenectomy for transitional cell carcinoma of the bladder...
  9. ncbi Concomitant carcinoma in situ is a feature of aggressive disease in patients with organ-confined TCC at radical cystectomy
    Shahrokh F Shariat
    Department of Urology, University of Texas Southwestern Medical Center, Dallas, TX 75390 9110, USA
    Eur Urol 51:152-60. 2007
    ..The aim of this study was to assess whether presence of concomitant CIS has a detrimental effect on cancer control after radical cystectomy...
  10. ncbi Association of the circulating levels of the urokinase system of plasminogen activation with the presence of prostate cancer and invasion, progression, and metastasis
    Shahrokh F Shariat
    Department of Urology, The University of Texas Southwestern Medical Center, Dallas, TX 75390 9110, USA
    J Clin Oncol 25:349-55. 2007
    ..To assess whether preoperative plasma levels of urokinase-type plasminogen activator (uPA) and its soluble receptor (uPAR) would predict cancer of the prostate (CaP) presence, stage, and prognosis...
  11. ncbi Variability in the performance of nuclear matrix protein 22 for the detection of bladder cancer
    Shahrokh F Shariat
    Department of Urology, University of Texas Southwestern Medical Center, 5323 Harry Hines Boulevard, Dallas, TX 75390, USA
    J Urol 176:919-26; discussion 926. 2006
    ..We assessed variability in the diagnostic performance of NMP22 for detecting recurrence and progression in patients with Ta, T1, and/or CIS transitional cell carcinoma of the bladder in a large international cohort...
  12. ncbi External validation of a biomarker-based preoperative nomogram predicts biochemical recurrence after radical prostatectomy
    Shahrokh F Shariat
    Cancer Prognostics and Health Outcomes Unit, University of Montreal, Montreal, Quebec, Canada
    J Clin Oncol 26:1526-31. 2008
    ..However, this model was never externally validated. We tested the accuracy of this nomogram in an independent, external cohort...
  13. ncbi Cooperative effect of cell-cycle regulators expression on bladder cancer development and biologic aggressiveness
    Shahrokh F Shariat
    Department of Urology, University of Texas Southwestern Medical Center, Dallas, TX 75390 9110, USA
    Mod Pathol 20:445-59. 2007
    ..In contrast to the use of single biological markers, evaluation of their combined status may improve prognostic models and help identify patients who might benefit from adjuvant therapies and in decision-making...
  14. ncbi Prognostic value of syndecan-1 expression in patients treated with radical prostatectomy
    Shahrokh F Shariat
    Department of Urology, University of Texas Southwestern Medical Center, Dallas, TX 75390 9110, USA
    BJU Int 101:232-7. 2008
    ....
  15. ncbi Multiple biomarkers improve prediction of bladder cancer recurrence and mortality in patients undergoing cystectomy
    Shahrokh F Shariat
    Department of Urology, University of Texas Southwestern Medical Center, Dallas, Texas 75390 9110, USA
    Cancer 112:315-25. 2008
    ....
  16. ncbi Association of cyclin D1 and E1 expression with disease progression and biomarkers in patients with nonmuscle-invasive urothelial cell carcinoma of the bladder
    Shahrokh F Shariat
    Department of Urology, University of Texas Southwestern Medical Center at Dallas, Dallas, TX 75390 9110, USA
    Urol Oncol 25:468-75. 2007
    ..To determine the association of cyclin D1 and E1 expression with bladder cancer presence, clinical and molecular characteristics, and disease progression in patients with nonmuscle-invasive urothelial cell carcinoma of the bladder...
  17. ncbi Plasminogen activation inhibitor-1 improves the predictive accuracy of prostate cancer nomograms
    Shahrokh F Shariat
    Department of Urology, University of Texas Southwestern Medical Center, Dallas, Texas 75390 9110, USA
    J Urol 178:1229-36; discussion 1236-7. 2007
    ....
  18. ncbi Blood biomarkers for prostate cancer detection and prognosis
    Shahrokh F Shariat
    University of Texas Southwestern Medical Center, Department of Urology, 5323 Harry Hines Boulevard, Dallas, TX 75390 9110, USA
    Future Oncol 3:449-61. 2007
    ..With recent advances in biotechnology such as high-throughput molecular analyses, many potential blood biomarkers have been identified and are currently under investigation...
  19. ncbi Nomograms for bladder cancer
    Shahrokh F Shariat
    Department of Urology, The University of Texas Southwestern Medical Center, Dallas, TX 75390 9110, USA
    Eur Urol 54:41-53. 2008
    ..Physicians need tools to accurately estimate the risk of recurrence and cancer-specific mortality to recommend individualized therapy and to design appropriate clinical trials...
  20. ncbi Herbal/hormonal dietary supplement possibly associated with prostate cancer progression
    Shahrokh F Shariat
    Department of Urology, University of Texas Southwestern Medical Center, Dallas, TX 75390 9110, USA
    Clin Cancer Res 14:607-11. 2008
    ..After two men developed an unusual course of clinically aggressive prostate cancer within months of starting daily consumption of the same HHDS product, we investigated the effect of this product on prostate cancer progression...
  21. ncbi Early postoperative plasma transforming growth factor-beta1 is a strong predictor of biochemical progression after radical prostatectomy
    Shahrokh F Shariat
    Department of Urology, University of Texas Southwestern Medical Center, Dallas, Texas 75390 9110, USA
    J Urol 179:1593-7. 2008
    ....
  22. ncbi Evidence-based validation of the predictive value of the American Association for the Surgery of Trauma kidney injury scale
    Shahrokh F Shariat
    Department of Urology, University of Texas Southwestern Medical Center at Dallas, Texas 75390 9110, USA
    J Trauma 62:933-9. 2007
    ..To evaluate the predictive value of the American Association for the Surgery of Trauma (AAST) kidney injury scale for the management of traumatic renal injuries...
  23. ncbi Discrepancy between clinical and pathologic stage: impact on prognosis after radical cystectomy
    Shahrokh F Shariat
    Department of Urology, University of Texas Southwestern Medical Center, Dallas, Texas 75390 9110, USA
    Eur Urol 51:137-49; discussion 149-51. 2007
    ..We compared clinical and pathologic staging in a large, contemporary, consecutive series of patients who were treated with radical cystectomy and pelvic lymphadenectomy, and determined the effect of stage discrepancy on outcomes...
  24. ncbi Nomograms including nuclear matrix protein 22 for prediction of disease recurrence and progression in patients with Ta, T1 or CIS transitional cell carcinoma of the bladder
    Shahrokh F Shariat
    Department of Urology, The University of Texas Southwestern Medical Center, Dallas, Texas 75390 9110, USA
    J Urol 173:1518-25. 2005
    ..We developed and validated nomograms that accurately predict disease recurrence and progression in patients with Ta, T1, or CIS transitional cell carcinoma (TCC) of the bladder using a large international cohort...
  25. ncbi New blood-based biomarkers for the diagnosis, staging and prognosis of prostate cancer
    Shahrokh F Shariat
    Department of Urology, University of Texas Southwestern Medical Center in Dallas, Texas 75390 9110, USA
    BJU Int 101:675-83. 2008
    ....
  26. ncbi Urinary levels of tumor-associated trypsin inhibitor (TATI) in the detection of transitional cell carcinoma of the urinary bladder
    Shahrokh F Shariat
    Department of Urology, University of Texas Southwestern Medical Center, Dallas, 75390 9110, USA
    Eur Urol 48:424-31. 2005
    ....
  27. ncbi Urinary levels of soluble e-cadherin in the detection of transitional cell carcinoma of the urinary bladder
    Shahrokh F Shariat
    Department of Urology, University of Texas Southwestern Medical School 5323 Harry Hines Blvd, Dallas, Texas 75390 9110, USA
    Eur Urol 48:69-76. 2005
    ..To test the hypothesis that elevated urinary levels of soluble E-cadherin (sE-cadherin) would aid in the detection of transitional cell carcinoma (TCC) of the urinary bladder...
  28. ncbi Urine cytology and urine-based markers for bladder urothelial carcinoma detection and monitoring: developments and future prospects
    Shahrokh F Shariat
    The University of Texas Southwestern Medical Center, Department of Urology, 5323 Harry Hines Boulevard, Dallas, TX 75390 9110, USA
    Biomark Med 2:165-80. 2008
    ..An ideal bladder cancer test would be noninvasive, highly sensitive and specific, inexpensive, easy to perform and yield highly reproducible results. Many of the tests reviewed herein meet some, but not all, of these criteria...
  29. ncbi Risk stratification for bladder tumor recurrence, stage and grade by urinary nuclear matrix protein 22 and cytology
    Shahrokh F Shariat
    Department of Urology, University of Texas Southwestern Medical Center, 5323 Harry Hines Boulevard, Dallas, TX 75390 9110, USA
    Eur Urol 45:304-13; author reply 313. 2004
    ....
  30. ncbi Survivin expression is associated with features of biologically aggressive prostate carcinoma
    Shahrokh F Shariat
    Department of Urology, University of Texas Southwestern Medical Center, Dallas, Texas 75390 91120, USA
    Cancer 100:751-7. 2004
    ....
  31. ncbi Gastrointestinal hemorrhage as first manifestation of metastatic testicular tumor
    Shahrokh F Shariat
    Department of Urology, University of Texas Southwestern Medical School, Dallas, Texas 75390 9110, USA
    Urology 66:1319. 2005
    ..He underwent ileal enterectomy, radical orchiectomy, and several cycles of chemotherapy (cisplatin, etoposide, and bleomycin). He died within 41 days of diagnosis...
  32. ncbi Correlation of cyclin D1 and E1 expression with bladder cancer presence, invasion, progression, and metastasis
    Shahrokh F Shariat
    Department of Urology, University of Texas Southwestern Medical Center at Dallas, TX 75390 9110, USA
    Hum Pathol 37:1568-76. 2006
    ..Cyclin E1 expression stratifies patients with bladder transitional cell carcinoma into those with more "indolent" behavior and those with features of biologically and clinically aggressive disease...
  33. ncbi Pre-operative percent free PSA predicts clinical outcomes in patients treated with radical prostatectomy with total PSA levels below 10 ng/ml
    Shahrokh F Shariat
    Department of Urology, The University of Texas Southwestern Medical Center at Dallas, TX 75390 9110, USA
    Eur Urol 49:293-302. 2006
    ..To evaluate the association of total prostate specific antigen (T-PSA) and percent free PSA (%F-PSA) with prostate cancer outcomes in patients treated with radical prostatectomy (RP)...
  34. ncbi Molecular markers in bladder cancer
    Shahrokh F Shariat
    Department of Urology, UT Southwestern Medical Center, Dallas, Texas 75390 9110, USA
    Curr Opin Urol 18:1-8. 2008
    ..Bladder cancer is a diverse disease whose molecular phenotypes are being elucidated. In this review, we summarize currently known molecular pathways and associated markers in bladder cancer...
  35. ncbi A population based assessment of perioperative mortality after cystectomy for bladder cancer
    Hendrik Isbarn
    Cancer Prognostics and Health Outcomes Unit, University of Montreal Health Center, Montreal, Quebec, Canada
    J Urol 182:70-7. 2009
    ..Contemporary estimates range from 0.7% to 5.6%. We tested several predictors of perioperative mortality and devised a model for individual perioperative mortality prediction...
  36. ncbi Propensity-score-matched comparison of perioperative outcomes between open and laparoscopic nephroureterectomy: a national series
    Nawar Hanna
    Cancer Prognostics and Health Outcomes Unit, University of Montreal Health Center, Montreal, Canada
    Eur Urol 61:715-21. 2012
    ..Either an open NU (ONU) or a laparoscopic NU (LNU) may be considered. Despite the presence of several reports comparing perioperative and cancer-control outcomes between the two approaches, no reports relied on a population-based cohort...
  37. ncbi Predictive value of the differential expression of the urokinase plasminogen activation axis in radical prostatectomy patients
    Amit Gupta
    Department of Urology, University of Texas Southwestern Medical Center, Dallas, Texas 75390 9110, USA
    Eur Urol 55:1124-33. 2009
    ..This axis is involved in cell proliferation, angiogenesis, extracellular matrix degradation, invasion, and metastases...
  38. ncbi Predictive value of combined immunohistochemical markers in patients with pT1 urothelial carcinoma at radical cystectomy
    Shahrokh F Shariat
    Department of Urology, University of Texas Southwestern Medical Center, Dallas, Texas, USA
    J Urol 182:78-84; discussion 84. 2009
    ..We tested whether the combination of immunohistochemical markers could risk stratify cases of pT1 urothelial carcinoma of the bladder at radical cystectomy...
  39. ncbi Nephroureterectomy and segmental ureterectomy in the treatment of invasive upper tract urothelial carcinoma: a population-based study of 2299 patients
    Giovanni Lughezzani
    Cancer Prognosis and Health Outcomes Unit, University of Montreal Health Center, Montreal, QC, Canada, H2X 3J4
    Eur J Cancer 45:3291-7. 2009
    ..We tested the prognostic impact of pT and pN stages on cancer-specific mortality (CSM) in a large population-based cohort of surgically treated patients with UTUC...
  40. ncbi Lymphovascular invasion is independently associated with overall survival, cause-specific survival, and local and distant recurrence in patients with negative lymph nodes at radical cystectomy
    Yair Lotan
    Department of Urology, The University of Texas Southwestern Medical Center at Dallas, Dallas, TX 75390 9110, USA
    J Clin Oncol 23:6533-9. 2005
    ..We hypothesized that bladder cancer patients with associated lymphovascular invasion (LVI) are at increased risk of occult metastases...
  41. ncbi Pre-treatment biomarker levels improve the accuracy of post-prostatectomy nomogram for prediction of biochemical recurrence
    Robert S Svatek
    Department of Urology, University of Texas Southwestern Medical Centre, 1515 Holcombe Blvd, Houston, TX 77030, USA
    Prostate 69:886-94. 2009
    ..We tested the ability of several pre-operative blood-based biomarkers to enhance the accuracy of standard post-operative features for the prediction of biochemical recurrence (BCR) after radical prostatectomy (RP)...
  42. ncbi A population-based assessment of the National Comprehensive Cancer Network practice guideline indications for pelvic lymph node dissection at radical prostatectomy
    Firas Abdollah
    Cancer Prognostics and Health Outcomes Unit, Department of Urology, Vita Salute San Raffaele University, Milan, Italy
    BJU Int 109:1177-82. 2012
    ..The 2010 NCCN practice guidelines for prostate cancer recommend a pelvic lymph node dissection (PLND) at radical prostatectomy in all individuals with a nomogram predicted LNI risk of ≥2%...
  43. ncbi Head-to-head comparison of three commonly used preoperative tools for prediction of lymph node invasion at radical prostatectomy
    Firas Abdollah
    Cancer Prognostics and Health Outcomes Unit, University of Montreal Health Centre, Montreal, Canada
    Urology 78:1363-7. 2011
    ....
  44. ncbi External validation of the updated partin tables in a cohort of French and Italian men
    Naeem Bhojani
    Cancer Prognostics and Health Outcomes Unit, University of Montreal, Montreal, PQ, Canada
    Int J Radiat Oncol Biol Phys 73:347-52. 2009
    ..To test the discrimination and calibration properties of the newly developed 2007 Partin Tables in two European cohorts with localized prostate cancer...
  45. ncbi Tumor grade improves the prognostic ability of American Joint Committee on Cancer stage in patients with penile carcinoma
    Rodolphe Thuret
    Cancer Prognostics and Health Outcomes Unit, University of Montreal, Montreal, Quebec, Canada
    J Urol 185:501-7. 2011
    ..Penile cancer is rare. Thus, predicting cancer specific mortality may be difficult. We devised an accurate and yet easily applicable predictive rule that compares favorably with 2 previous models (73.8% and 74.7% accuracy, respectively)...
  46. ncbi Lymph node count threshold for optimal pelvic lymph node staging in prostate cancer
    Firas Abdollah
    Cancer Prognostics and Health Outcomes Unit, University of Montreal Health Centre, Montreal, Quebec, Canada
    Int J Urol 19:645-51. 2012
    ....
  47. ncbi Predicting clinical outcomes after radical nephroureterectomy for upper tract urothelial carcinoma
    Eugene K Cha
    Department of Urology, Weill Cornell Medical College, New York Presbyterian Hospital, New York, NY 10065, USA
    Eur Urol 61:818-25. 2012
    ..Novel prognostic factors for patients after radical nephroureterectomy (RNU) for upper tract urothelial carcinoma (UTUC) have recently been described...
  48. ncbi Competing-risks mortality after radiotherapy vs. observation for localized prostate cancer: a population-based study
    Firas Abdollah
    Cancer Prognostics and Health Outcomes Unit, University of Montreal Health Centre, Montreal, Canada
    Int J Radiat Oncol Biol Phys 84:95-103. 2012
    ..Our objective was to test the relationship between radiotherapy and survival in men with localized PCa and compare it with those treated with observation...
  49. ncbi Trends of retroperitoneal lymphadenectomy use in patients with nonseminomatous germ cell tumor of the testis: a population-based study
    Maxine Sun
    Cancer Prognostics and Health Outcomes Unit, University of Montreal Health Center CHUM, Montreal, QC, Canada
    Ann Surg Oncol 18:2997-3004. 2011
    ..Our objective was to assess the utilization rate of RPLND in patients with NSGCTT...
  50. ncbi Use of preoperative plasma endoglin for prediction of lymph node metastasis in patients with clinically localized prostate cancer
    Jose A Karam
    Department of Urology, The University of Texas Southwestern Medical Center, Dallas, Texas 75390 9110, USA
    Clin Cancer Res 14:1418-22. 2008
    ..The aim of the study was to evaluate whether preoperative plasma endoglin improves the prediction of lymph node metastases in patients with clinically localized prostate cancer...
  51. ncbi Gender-related differences in patients with stage I to III upper tract urothelial carcinoma: results from the Surveillance, Epidemiology, and End Results database
    Giovanni Lughezzani
    Cancer Prognosis and Health Outcomes Unit, University of Montreal Health Center, Montreal, Quebec, Canada
    Urology 75:321-7. 2010
    ..To examine the effect of gender in upper tract urothelial carcinoma (UTUC) stage at nephroureterectomy (NU), as well as on cancer-specific mortality (CSM) after NU in patients with American Joint Committee on Cancer stages I-III UTUC...
  52. ncbi Limited prognostic value of tumor necrosis in patients with renal cell carcinoma
    Hendrik Isbarn
    Cancer Prognostics and Health Outcomes Unit, University of Montreal Health Center, Montreal, Quebec, Canada
    Urology 75:1378-84. 2010
    ..However, its added prognostic value along with established cancer-specific mortality (CSM) predictors has never been formally tested...
  53. ncbi Comparison of oncologic outcomes for open and laparoscopic nephroureterectomy: a multi-institutional analysis of 1249 cases
    Umberto Capitanio
    Cancer Prognostics and Health Outcomes Unit, University of Montreal Health Center, Montreal, Quebec, Canada
    Eur Urol 56:1-9. 2009
    ..Data regarding the oncologic efficacy of laparoscopic nephroureterectomy (LNU) compared to open nephroureterectomy (ONU) are scarce...
  54. ncbi A population-based comparison of cancer-control rates between radical and partial nephrectomy for T1A renal cell carcinoma
    Maxime Crepel
    Cancer Prognostics and Health Outcomes Unit, University of Montreal, Montreal, Quebec, Canada
    Urology 76:883-8. 2010
    ..We relied on the surveillance, epidemiology, and end results (SEER) database and assessed cancer-specific mortality (CSM) after either PN or RN for T1aN0M0 RCC, in competing-risks models...
  55. ncbi Survival benefit of radical prostatectomy in patients with localized prostate cancer: estimations of the number needed to treat according to tumor and patient characteristics
    Firas Abdollah
    Cancer Prognostics and Health Outcomes Unit, University of Montreal Health Centre, Montreal, Quebec, Canada
    J Urol 188:73-83. 2012
    ..We assessed the relationship between treatment type (radical prostatectomy vs observation) and cancer specific mortality in a large, population based cohort...
  56. ncbi Nomogram for predicting disease recurrence after radical cystectomy for transitional cell carcinoma of the bladder
    Pierre I Karakiewicz
    Cancer Prognostics and Health Outcomes Unit, University of Montreal, Montreal, Quebec, Canada
    J Urol 176:1354-61; discussion 1361-2. 2006
    ....
  57. ncbi p53 expression in patients with advanced urothelial cancer of the urinary bladder
    Shahrokh F Shariat
    Department of Urology, University of Texas Southwestern Medical Center, Dallas, TX, USA
    BJU Int 105:489-95. 2010
    ..To test whether assessing p53 expression could improve the ability to predict disease recurrence and disease-specific survival in a multi-institutional cohort of patients with advanced urothelial carcinoma of the urinary bladder (UCB)...
  58. ncbi Survivin as a prognostic marker for urothelial carcinoma of the bladder: a multicenter external validation study
    Shahrokh F Shariat
    Departments of Urology and Pathology, University of Texas Southwestern Medical Center, Dallas, Texas, USA
    Clin Cancer Res 15:7012-9. 2009
    ..Specimens showing at least 10% reactivity were considered altered. Predictive accuracy was quantified using the concordance index and 200-bootstrap resamples were used to reduce overfit bias...
  59. ncbi Combination of multiple molecular markers can improve prognostication in patients with locally advanced and lymph node positive bladder cancer
    Shahrokh F Shariat
    Department of Urology, University of Texas Southwestern Medical Center, Dallas, Texas 10065, USA
    J Urol 183:68-75. 2010
    ..We also assessed whether the combination of molecular markers is superior to any individual biomarker...
  60. ncbi Use of combined apoptosis biomarkers for prediction of bladder cancer recurrence and mortality after radical cystectomy
    Jose A Karam
    Department of Urology, University of Texas Southwestern Medical Center, Dallas, TX 75390, USA
    Lancet Oncol 8:128-36. 2007
    ....
  61. ncbi Association of angiogenesis related markers with bladder cancer outcomes and other molecular markers
    Shahrokh F Shariat
    Department of Urology, University of Texas Southwestern Medical Center, Dallas, Texas, USA
    J Urol 183:1744-50. 2010
    ....
  62. ncbi A competing-risks analysis of survival after alternative treatment modalities for prostate cancer patients: 1988-2006
    Firas Abdollah
    Cancer Prognostics and Health Outcomes Unit, University of Montreal Health Center, Montreal, Canada
    Eur Urol 59:88-95. 2011
    ..The efficacy of prostate cancer (PCa) treatment modalities is a subject of continuous debate...
  63. ncbi Age-adjusted incidence, mortality, and survival rates of stage-specific renal cell carcinoma in North America: a trend analysis
    Maxine Sun
    Cancer Prognostics and Health Outcomes Unit, University of Montreal Health Center, Montreal, Canada
    Eur Urol 59:135-41. 2011
    ..The rising incidence of renal cell carcinoma (RCC) has been largely attributed to the increasing use of imaging procedures...
  64. ncbi A nomogram predicting 10-year life expectancy in candidates for radical prostatectomy or radiotherapy for prostate cancer
    Jochen Walz
    Cancer Prognostics and Health Outcomes Unit, University of Montreal Health Center, Montreal, Quebec, Canada
    J Clin Oncol 25:3576-81. 2007
    ..To circumvent this problem, we developed a nomogram predicting 10-year LE for patients treated with either radical prostatectomy (RP) or external-beam radiation therapy (EBRT) and compared it with an existing tool...
  65. ncbi Critical assessment of the European Association of Urology guideline indications for pelvic lymph node dissection at radical prostatectomy
    Firas Abdollah
    Cancer Prognostics and Health Outcomes Unit, University of Montreal Health Centre, Montreal, Canada
    BJU Int 108:1769-75. 2011
    ..We presented the first formal validation of the 2010 European Association of Urology guidelines for lymphadenectomy in prostate cancer patients...
  66. ncbi The rate of secondary malignancies after radical prostatectomy versus external beam radiation therapy for localized prostate cancer: a population-based study on 17,845 patients
    Naeem Bhojani
    Cancer Prognostics and Health Outcomes Unit, University of Montreal Health Center, Montreal, QC, Canada
    Int J Radiat Oncol Biol Phys 76:342-8. 2010
    ..We tested this hypothesis in a large French Canadian population-based cohort of prostate cancer patients...
  67. ncbi Chronological age is not an independent predictor of clinical outcomes after radical nephroureterectomy
    Thomas F Chromecki
    Department of Urology, Weill Cornell Medical Center, New York Presbyterian Hospital, New York, NY 10065, USA
    World J Urol 29:473-80. 2011
    ..The aim of the current study was to test this hypothesis in a large multicenter external validation cohort of patients treated with radical nephroureterectomy (RNU) while controlling for patient performance status...
  68. ncbi Temporal stage and grade migration in surgically treated patients with upper tract urothelial carcinoma
    Giovanni Lughezzani
    University of Montreal Health Center, Montreal, Canada
    BJU Int 105:799-804. 2010
    ..Study Type - Therapy (individual cohort) Level of Evidence 2b..
  69. ncbi Should bladder cuff excision remain the standard of care at nephroureterectomy in patients with urothelial carcinoma of the renal pelvis? A population-based study
    Giovanni Lughezzani
    Cancer Prognosis and Health Outcomes Unit, University of Montreal Health Center, Montreal, Quebec, Canada
    Eur Urol 57:956-62. 2010
    ..A large, multi-institutional, tertiary care center study suggested no benefit from bladder cuff excision (BCE) at nephroureterectomy in patients with upper tract urothelial carcinoma (UC)...
  70. ncbi Adjuvant chemotherapy for bladder cancer does not alter cancer-specific survival after cystectomy in a matched case-control study
    Jochen Walz
    Cancer Prgonosis and Health Outcomes Unit, University of Montreal, Montreal, Quebec, Canada
    BJU Int 101:1356-61. 2008
    ....
  71. ncbi Comparison of stage migration patterns between Europe and the USA: an analysis of 11 350 men treated with radical prostatectomy for prostate cancer
    Andrea Gallina
    Cancer Prognostics and Health Outcomes Unit, University of Montreal, Montreal, Quebec, Canada
    BJU Int 101:1513-8. 2008
    ..To examine the stage migration patterns in patients treated with radical prostatectomy (RP) for prostate cancer in Europe and in the USA in the last 20 years...
  72. ncbi A critical appraisal of the value of lymph node dissection at nephroureterectomy for upper tract urothelial carcinoma
    Giovanni Lughezzani
    Cancer Prognosis and Health Outcomes Unit, University of Montreal Health Center, Montreal, Quebec, Canada
    Urology 75:118-24. 2010
    ....
  73. ncbi Nomograms provide improved accuracy for predicting survival after radical cystectomy
    Shahrokh F Shariat
    Department of Urology, University of Texas Southwestern Medical Center, Dallas, Texas, and The Brady Urological Institute, The Johns Hopkins Hospital, Baltimore, MD, USA
    Clin Cancer Res 12:6663-76. 2006
    ....
  74. ncbi High surgical volume is associated with a lower rate of secondary therapy after radical prostatectomy for localized prostate cancer
    Claudio Jeldres
    Cancer Prognostics and Health Outcomes Unit, University of Montreal Health Center, Montreal, Quebec, Canada
    BJU Int 102:463-7. 2008
    ....
  75. ncbi Caveolin-1 overexpression is associated with aggressive prostate cancer recurrence
    Jose A Karam
    Department of Urology, University of Texas Southwestern Medical Center, Dallas, TX 75390 9110, USA
    Prostate 67:614-22. 2007
    ....
  76. ncbi Body mass index and its association with genitourinary disorders in men undergoing prostate cancer screening
    Naeem Bhojani
    Cancer Prognostics and Health Outcomes Unit, University of Montreal Health Center, Montreal, Quebec, Canada
    J Sex Med 5:2141-51. 2008
    ..Elevated body mass index (BMI) may predispose to several pelvic pathologies...
  77. ncbi Ki-67 is an independent predictor of bladder cancer outcome in patients treated with radical cystectomy for organ-confined disease
    Vitaly Margulis
    Department of Urology, University of Texas Southwestern Medical Center, Dallas, Texas 75390-9110, USA
    Clin Cancer Res 12:7369-73. 2006
    ..041). CONCLUSIONS: Ki-67 overexpression is associated with features of aggressive bladder TCC and adds independent prognostic information to standard pathologic features for prediction of clinical outcome after radical cystectomy...
  78. ncbi Decreased DOC-2/DAB2 expression in urothelial carcinoma of the bladder
    Jose A Karam
    Department of Urology, University of Texas Southwestern Medical Center at Dallas, Dallas, Texas, USA
    Clin Cancer Res 13:4400-6. 2007
    ..Little is known about the expression of this gene in urothelial carcinoma of the bladder (UCB). We profiled DOC-2/DAB2 expression in mouse and human normal and neoplastic urothelia...
  79. ncbi Prostate cancer disease-free survival after radical retropubic prostatectomy in patients older than 70 years compared to younger cohorts
    Bahaa S Malaeb
    Department of Urology, University of Minnesota, Minneapolis, MN 55455, USA
    Urol Oncol 25:291-7. 2007
    ..To evaluate the feasibility of radical retropubic prostatectomy (RRP) as an option for treating men older than 70 years with organ confined prostate cancer and to compare biochemical progression-free survival with younger cohorts...
  80. ncbi Preoperative plasma levels of interleukin-6 and its soluble receptor predict disease recurrence and survival of patients with bladder cancer
    Ben Andrews
    Scott Department of Urology, Baylor College of Medicine and The Methodist Hospital, Houston, Texas, USA
    J Urol 167:1475-81. 2002
    ..Levels of IL-6 and IL-6sR were associated with cancer stage and metastases, and were strong independent predictors of disease recurrence and disease specific survival...
  81. ncbi Development and split-sample validation of a nomogram predicting the probability of seminal vesicle invasion at radical prostatectomy
    Andrea Gallina
    Cancer Prognostics and Health Outcomes Unit, University of Montreal, Montreal, Quebec, Canada
    Eur Urol 52:98-105. 2007
    ..We hypothesized that contemporary patients, at very low risk of seminal vesicle invasion (SVI), can be highly accurately identified with an equally contemporary SVI nomogram...
  82. ncbi Predictive value of plasma hepatocyte growth factor/scatter factor levels in patients with clinically localized prostate cancer
    Amit Gupta
    Department of Urology, The University of Texas Southwestern Medical Center, Dallas, Texas 75390 9110, USA
    Clin Cancer Res 14:7385-90. 2008
    ..We assessed whether preoperative plasma levels of HGF can enhance the accuracy of standard models for predicting pathologic features and clinical outcomes...
  83. ncbi Survivin expression in patients with non-muscle-invasive urothelial cell carcinoma of the bladder
    Jose A Karam
    Department of Urology, University of Texas Southwestern Medical Center at Dallas, Dallas, Texas 75390 9110, USA
    Urology 70:482-6. 2007
    ..Our objectives were to evaluate the association of survivin expression with the presence of urothelial cell carcinoma of the bladder and clinical outcomes in patients with non-muscle-invasive urothelial cell carcinoma of the bladder...
  84. ncbi External validation of the updated Partin tables in a cohort of North American men
    Pierre I Karakiewicz
    Cancer Prognostics and Health Outcomes Unit and Department of Urology, University of Montreal, Montreal, Quebec, Canada
    J Urol 180:898-902; discussion 902-3. 2008
    ..The Partin tables were updated in 2007. However, to our knowledge their accuracy and performance characteristics have not been confirmed in an external validation cohort...
  85. ncbi Salvage radiotherapy for recurrent prostate cancer after radical prostatectomy
    Andrew J Stephenson
    Department of Urology, Sidney Kimmel Center for Prostate and Urologic Cancers, Memorial Sloan-Kettering Cancer Center, New York, NY, USA
    JAMA 291:1325-32. 2004
    ..Selected patients with high-grade disease and/or a rapid PSADT who were previously thought to be destined to develop progressive metastatic disease may achieve a durable response to salvage radiotherapy...
  86. ncbi Soluble Fas--a promising novel urinary marker for the detection of recurrent superficial bladder cancer
    Robert S Svatek
    Department of Urology, University of Texas Southwestern Medical Center, Dallas, Texas 75390 9110, USA
    Cancer 106:1701-7. 2006
    ....
  87. ncbi Predictive value of primary Gleason pattern 4 in patients with Gleason score 7 tumours treated with radical prostatectomy
    Seyed M Khoddami
    Department of Urology, The University of Texas South-western Medical Center, Dallas, USA
    BJU Int 94:42-6. 2004
    ..Recognising the distinction in GS 7 between predominant 4 vs 3 scores after radical prostatectomy should improve the ability of clinicians to counsel patients. The GS 4 pattern deserves further molecular study...
  88. ncbi Association of p53 and p21 expression with clinical outcome in patients with carcinoma in situ of the urinary bladder
    Shahrokh F Shariat
    Scott Department of Urology, Baylor College of Medicine and Methodist Hospital, Houston, Texas, USA
    Urology 61:1140-5. 2003
    ..To determine whether p53 and p21 expression in bladder carcinoma in situ (CIS) with or without papillary disease can predict disease recurrence, progression, and survival...
  89. ncbi Mortality at 120 days after prostatic biopsy: a population-based study of 22,175 men
    Andrea Gallina
    Cancer Prognostics and Health Outcomes Unit, University of Montreal, Montreal, Quebec, Canada
    Int J Cancer 123:647-52. 2008
    ..In conclusion, our data suggest that prostate biopsy might predispose to higher mortality rate. The certainty of this association remains to be proven...
  90. ncbi Role of urinary cathepsin B and L in the detection of bladder urothelial cell carcinoma
    Robert S Svatek
    Department of Urology, University of Texas Southwestern Medical Center, Dallas, Texas, USA
    J Urol 179:478-84; discussion 484. 2008
    ..We tested the hypothesis that urinary cathepsin B and L are associated with bladder cancer recurrence and invasiveness in patients with a history of nonmuscle invasive urothelial carcinoma of the bladder...
  91. ncbi Impact of clinical factors, including a point-of-care nuclear matrix protein-22 assay and cytology, on bladder cancer detection
    Yair Lotan
    Cancer Prognostics and Health Outcomes Unit, University of Montreal Health Center, Montreal, Quebec, Canada
    BJU Int 103:1368-74. 2009
    ..To determine whether the nuclear matrix protein-22 (NMP22) assay can improve the accuracy of discriminating between high-risk patients with and without bladder cancer...
  92. ncbi Accuracy of life tables in predicting overall survival in candidates for radiotherapy for prostate cancer
    Jochen Walz
    Cancer Prognostics and Health Outcomes Unit, University of Montreal, Montreal, Quebec, Canada
    Int J Radiat Oncol Biol Phys 69:88-94. 2007
    ..To test the accuracy of life tables (LTs) in predicting survival in men treated with radiotherapy for localized prostate cancer...
  93. ncbi Expression of survivin and apoptotic biomarkers in benign prostatic hyperplasia
    Shahrokh F Shariat
    Department of Urology, University of Texas Southwestern Medical Center, Dallas, Texas 75390-9110, USA
    J Urol 174:2046-50. 2005
    ..CONCLUSIONS: Survivin is over expressed in BPH and it correlates with BPH parameters. Increases in proliferation and inhibition of apoptosis have a role in BPH...
  94. ncbi p53 predictive value for pT1-2 N0 disease at radical cystectomy
    Shahrokh F Shariat
    Department of Urology, University of Texas Southwestern Medical Center, Dallas, USA
    J Urol 182:907-13. 2009
    ..We determined whether p53 expression would improve the prediction of disease progression after radical cystectomy for pT1-2N0M0 UCB...
  95. ncbi Expression of cyclooxygenase-2 in normal urothelium, and superficial and advanced transitional cell carcinoma of bladder
    Vitaly Margulis
    Department of Urology, University of Texas Southwestern Medical Center at Dallas, Dallas, Texas 75390 9110, USA
    J Urol 177:1163-8. 2007
    ....
  96. ncbi The addition of urinary urokinase-type plasminogen activator to urinary nuclear matrix protein 22 and cytology improves the detection of bladder cancer
    Shahrokh F Shariat
    Scott Department of Urology, Baylor College of Medicine, Houston, Texas 77030, USA
    J Urol 170:2244-7. 2003
    ..An approach using multiple biomarkers may improve the diagnostic accuracy of voided urinary diagnostic tests...
  97. ncbi p53, p21, pRB, and p16 expression predict clinical outcome in cystectomy with bladder cancer
    Shahrokh F Shariat
    Scott Department of Urology, Baylor College of Medicine, 6560 Fannin, Suite 2100, Houston, TX 77030, USA
    J Clin Oncol 22:1014-24. 2004
    ....
  98. ncbi Early postoperative peripheral blood reverse transcription PCR assay for prostate-specific antigen is associated with prostate cancer progression in patients undergoing radical prostatectomy
    Shahrokh F Shariat
    Matsunaga-Conte Prostate Cancer Research Center, Scott Department of Urology, Baylor College of Medicine and The Methodist Hospital, Houston, Texas 77030, USA
    Cancer Res 63:5874-8. 2003
    ....
  99. ncbi Association of plasma urokinase-type plasminogen activator and its receptor with clinical outcome in patients undergoing radical cystectomy for transitional cell carcinoma of the bladder
    Shahrokh F Shariat
    Scott Department of Urology, Baylor College of Medicine and Methodist Hospital, Houston, Texas 77030, USA
    Urology 61:1053-8. 2003
    ..We tested the hypothesis that preoperative plasma levels of uPA and its specific receptor, uPAR, would predict cancer stage and prognosis in patients with transitional cell carcinoma of the bladder...
  100. ncbi The addition of interleukin-6 soluble receptor and transforming growth factor beta1 improves a preoperative nomogram for predicting biochemical progression in patients with clinically localized prostate cancer
    Michael W Kattan
    Scott Department of Urology, Baylor College of Medicine, 6535 Fannin St, Houston, TX 77030, USA
    J Clin Oncol 21:3573-9. 2003
    ....
  101. ncbi Macroscopic, but not microscopic, perivesical fat invasion at radical cystectomy is an adverse predictor of recurrence and survival
    Patrick J Bastian
    The James Buchanan Brady Urological Institute, The Johns Hopkins Hospital, Baltimore, MD, USA
    BJU Int 101:450-4. 2008
    ....