Lee A Shapiro

Summary

Affiliation: University of California
Country: USA

Publications

  1. ncbi request reprint Origin, migration and fate of newly generated neurons in the adult rodent piriform cortex
    Lee A Shapiro
    Department of Anatomy and Neurobiology, School of Medicine, University of California at Irvine, Irvine, CA 92697 1275, USA
    Brain Struct Funct 212:133-48. 2007
  2. ncbi request reprint Newly born dentate granule neurons after pilocarpine-induced epilepsy have hilar basal dendrites with immature synapses
    Lee A Shapiro
    Department of Anatomy and Neurobiology, School of Medicine, University of California, Irvine, CA 92697 1275, United States
    Epilepsy Res 69:53-66. 2006
  3. ncbi request reprint Newly generated granule cells show rapid neuroplastic changes in the adult rat dentate gyrus during the first five days following pilocarpine-induced seizures
    Lee A Shapiro
    Department of Anatomy and Neurobiology, School of Medicine, University of California, Irvine, CA 92697 1275, USA
    Eur J Neurosci 26:583-92. 2007
  4. ncbi request reprint Olfactory enrichment enhances the survival of newly born cortical neurons in adult mice
    Lee A Shapiro
    Department of Anatomy and Neurobiology, University of California at Irvine, Irvine, California 92697 1275, USA
    Neuroreport 18:981-5. 2007
  5. pmc Microglia-associated granule cell death in the normal adult dentate gyrus
    Charles E Ribak
    Department of Anatomy and Neurobiology, School of Medicine, University of California at Irvine, Irvine, CA 92697 1275, USA
    Brain Struct Funct 214:25-35. 2009
  6. ncbi request reprint GFAP-expressing radial glia-like cell bodies are involved in a one-to-one relationship with doublecortin-immunolabeled newborn neurons in the adult dentate gyrus
    Lee A Shapiro
    Department of Anatomy and Neurobiology, College of Medicine, University of California, Irvine, CA 92697 1275, USA
    Brain Res 1040:81-91. 2005
  7. doi request reprint Rapid astrocyte and microglial activation following pilocarpine-induced seizures in rats
    Lee A Shapiro
    Department of Anatomy and Neurobiology, School of Medicine, University of California at Irvine, Irvine, California 92697 1275, USA
    Epilepsia 49:33-41. 2008
  8. ncbi request reprint Spatiotemporal profile of dendritic outgrowth from newly born granule cells in the adult rat dentate gyrus
    Lee A Shapiro
    Department of Anatomy and Neurobiology, School of Medicine, University of California, Irvine, CA 92697 1275, USA
    Brain Res 1149:30-7. 2007
  9. doi request reprint Structural changes for adult-born dentate granule cells after status epilepticus
    Lee A Shapiro
    Department of Anatomy and Neurobiology, University of California, Irvine, California 92697 1275, USA
    Epilepsia 49:13-8. 2008
  10. ncbi request reprint Ultrastructure and synaptic connectivity of cell types in the adult rat dentate gyrus
    Charles E Ribak
    Department of Anatomy and Neurobiology, University of California at Irvine, Irvine, CA 92697 1275, USA
    Prog Brain Res 163:155-66. 2007

Detail Information

Publications15

  1. ncbi request reprint Origin, migration and fate of newly generated neurons in the adult rodent piriform cortex
    Lee A Shapiro
    Department of Anatomy and Neurobiology, School of Medicine, University of California at Irvine, Irvine, CA 92697 1275, USA
    Brain Struct Funct 212:133-48. 2007
    ....
  2. ncbi request reprint Newly born dentate granule neurons after pilocarpine-induced epilepsy have hilar basal dendrites with immature synapses
    Lee A Shapiro
    Department of Anatomy and Neurobiology, School of Medicine, University of California, Irvine, CA 92697 1275, United States
    Epilepsy Res 69:53-66. 2006
    ..The data also suggest that the synapses on DCX-labeled hilar basal dendrites contribute to the persistence of hilar basal dendrites on neurons born after pilocarpine-induced seizures...
  3. ncbi request reprint Newly generated granule cells show rapid neuroplastic changes in the adult rat dentate gyrus during the first five days following pilocarpine-induced seizures
    Lee A Shapiro
    Department of Anatomy and Neurobiology, School of Medicine, University of California, Irvine, CA 92697 1275, USA
    Eur J Neurosci 26:583-92. 2007
    ..The presence of synapses, albeit developing ones, on hilar basal dendrites during this period indicates that newly generated granule cells become rapidly incorporated into dentate gyrus circuitry following seizures...
  4. ncbi request reprint Olfactory enrichment enhances the survival of newly born cortical neurons in adult mice
    Lee A Shapiro
    Department of Anatomy and Neurobiology, University of California at Irvine, Irvine, California 92697 1275, USA
    Neuroreport 18:981-5. 2007
    ..These results confirm that neurogenesis occurs in the piriform cortex of rodents and suggest that it may play a neuroplastic role there...
  5. pmc Microglia-associated granule cell death in the normal adult dentate gyrus
    Charles E Ribak
    Department of Anatomy and Neurobiology, School of Medicine, University of California at Irvine, Irvine, CA 92697 1275, USA
    Brain Struct Funct 214:25-35. 2009
    ..Based on the morphological evidence, this type of cell death differs from either apoptosis or necrosis...
  6. ncbi request reprint GFAP-expressing radial glia-like cell bodies are involved in a one-to-one relationship with doublecortin-immunolabeled newborn neurons in the adult dentate gyrus
    Lee A Shapiro
    Department of Anatomy and Neurobiology, College of Medicine, University of California, Irvine, CA 92697 1275, USA
    Brain Res 1040:81-91. 2005
    ..These data show that GFAP-expressing radial glia-like cells in the dentate gyrus cradle newborn neurons in the subgranular zone and that their radial processes provide a scaffold for neuronal process outgrowth...
  7. doi request reprint Rapid astrocyte and microglial activation following pilocarpine-induced seizures in rats
    Lee A Shapiro
    Department of Anatomy and Neurobiology, School of Medicine, University of California at Irvine, Irvine, California 92697 1275, USA
    Epilepsia 49:33-41. 2008
    ..The differential response patterns of astrocytes and microglial cells following pilocarpine-induced seizures may signify their detrimental role in neuroinflammation after seizures...
  8. ncbi request reprint Spatiotemporal profile of dendritic outgrowth from newly born granule cells in the adult rat dentate gyrus
    Lee A Shapiro
    Department of Anatomy and Neurobiology, School of Medicine, University of California, Irvine, CA 92697 1275, USA
    Brain Res 1149:30-7. 2007
    ....
  9. doi request reprint Structural changes for adult-born dentate granule cells after status epilepticus
    Lee A Shapiro
    Department of Anatomy and Neurobiology, University of California, Irvine, California 92697 1275, USA
    Epilepsia 49:13-8. 2008
    ..This article will describe these structural alterations of granule cells found in the dentate gyrus after SE and will also discuss the time course of these events and possible underlying causes...
  10. ncbi request reprint Ultrastructure and synaptic connectivity of cell types in the adult rat dentate gyrus
    Charles E Ribak
    Department of Anatomy and Neurobiology, University of California at Irvine, Irvine, CA 92697 1275, USA
    Prog Brain Res 163:155-66. 2007
    ..This chapter provides a review of the ultrastructural features and synaptic connectivity of both projection cells and local circuit neurons in the dentate gyrus...
  11. pmc Dendritic development of newly generated neurons in the adult brain
    Charles E Ribak
    Department of Anatomy and Neurobiology, University of California at Irvine, Irvine, CA 92697 1275, USA
    Brain Res Rev 55:390-4. 2007
    ..Therefore, similarities and differences exist for dendritic outgrowth from newborn neurons in the developing and adult brain...
  12. ncbi request reprint Integration of newly born dentate granule cells into adult brains: hypotheses based on normal and epileptic rodents
    Lee A Shapiro
    Department of Anatomy and Neurobiology, College of Medicine, University of California, Irvine, Irvine, CA 92697, USA
    Brain Res Brain Res Rev 48:43-56. 2005
    ..In this review, granule cell development is discussed with relevance to the creation of the recurrent excitatory circuitry in rodent models of temporal lobe epilepsy...
  13. pmc In DRG11 knock-out mice, trigeminal cell death is extensive and does not account for failed brainstem patterning
    Mark F Jacquin
    Department of Neurology, Washington University School of Medicine, St Louis, Missouri 63110, USA
    J Neurosci 28:3577-85. 2008
    ..Thus, apoptotic cell death is not a sufficient cause of failed pattern formation in the PrV of the DRG11(-/-). A signaling pathway involving DRG11 may, therefore, be the elusive PrV pattern maker...
  14. ncbi request reprint Expression levels of cytoskeletal proteins indicate pathological aging of S100B transgenic mice: an immunohistochemical study of MAP-2, drebrin and GAP-43
    Lee A Shapiro
    Program in Biopsychology, Department of Psychology, State University of New York, Stony Brook, NY 11794 2500, USA
    Brain Res 1019:39-46. 2004
    ..Overall, the data suggest that S100B overexpression leads to changes in cytoskeletal markers. The longitudinal effects of S100B overexpression are discussed with relevance to aging and pathology...
  15. ncbi request reprint Increased clusterin expression in old but not young adult S100B transgenic mice: evidence of neuropathological aging in a model of Down Syndrome
    Lee A Shapiro
    Department of Psychology, State University of New York at Stony Brook, Stony Brook, NY 11794 2500, USA
    Brain Res 1010:17-21. 2004
    ..Our findings show increased clusterin expression in the aged S100B mice compared to their CD-1 controls, a finding we have interpreted as further evidence of pathological brain aging...