Alexandra Shapiro

Summary

Affiliation: University of Florida
Country: USA

Publications

  1. ncbi The act of voluntary wheel running reverses dietary hyperphagia and increases leptin signaling in ventral tegmental area of aged obese rats
    Alexandra Shapiro
    Department of Pharmacology and Therapeutics, College of Medicine, University of Florida, Gainesville, FL 32610, USA
    Gerontology 57:335-42. 2011
  2. ncbi Fructose-induced leptin resistance exacerbates weight gain in response to subsequent high-fat feeding
    Alexandra Shapiro
    Dept of Pharmacology and Therapeutics, Box 100267, Univ of Florida, Gainesville, Florida 32610, USA
    Am J Physiol Regul Integr Comp Physiol 295:R1370-5. 2008
  3. ncbi Prevention and reversal of diet-induced leptin resistance with a sugar-free diet despite high fat content
    Alexandra Shapiro
    Department of Pharmacology and Therapeutics, University of Florida, College of Medicine, Box 100267, Gainesville, FL 32610, USA
    Br J Nutr 106:390-7. 2011
  4. ncbi POMC overexpression in the ventral tegmental area ameliorates dietary obesity
    Lourdes M Andino
    Departments of Pharmacology and Therapeutics Aging and Geriatrics, University of Florida College of Medicine, PO Box 100267, Gainesville, Florida 32610, USA
    J Endocrinol 210:199-207. 2011
  5. ncbi Central overexpression of leptin antagonist reduces wheel running and underscores importance of endogenous leptin receptor activity in energy homeostasis
    Michael Matheny
    Department of Pharmacology and Therapeutic, University of Florida College of Medicine, Gainesville, Florida 32610, USA
    Am J Physiol Regul Integr Comp Physiol 297:R1254-61. 2009
  6. ncbi Synergy between leptin therapy and a seemingly negligible amount of voluntary wheel running prevents progression of dietary obesity in leptin-resistant rats
    Alexandra Shapiro
    Department of Pharmacology and Therapeutics, Box 100267, University of Florida College of Medicine, Gainesville, Florida 32610, USA
    Diabetes 57:614-22. 2008
  7. ncbi Molecular and biological characterization of a Cypovirus from the mosquito Culex restuans
    Terry B Green
    ARS, CMAVE, Gainesville, FL 32608, USA
    J Invertebr Pathol 91:27-34. 2006
  8. ncbi Morphological and molecular characterization of a Cypovirus (Reoviridae) from the mosquito Uranotaenia sapphirina (Diptera: Culicidae)
    Alexandra Shapiro
    Center for Medical, Agricultural and Veterinary Entomology, USDA/ARS, Gainesville, FL 32604, USA
    J Virol 79:9430-8. 2005

Collaborators

Detail Information

Publications8

  1. ncbi The act of voluntary wheel running reverses dietary hyperphagia and increases leptin signaling in ventral tegmental area of aged obese rats
    Alexandra Shapiro
    Department of Pharmacology and Therapeutics, College of Medicine, University of Florida, Gainesville, FL 32610, USA
    Gerontology 57:335-42. 2011
    ..It appears to trigger a response that substitutes for the reward of highly palatable food that may be mediated by increased leptin signaling in the VTA...
  2. ncbi Fructose-induced leptin resistance exacerbates weight gain in response to subsequent high-fat feeding
    Alexandra Shapiro
    Dept of Pharmacology and Therapeutics, Box 100267, Univ of Florida, Gainesville, Florida 32610, USA
    Am J Physiol Regul Integr Comp Physiol 295:R1370-5. 2008
    ..Our data indicate that chronic fructose consumption induces leptin resistance prior to body weight, adiposity, serum leptin, insulin, or glucose increases, and this fructose-induced leptin resistance accelerates high-fat induced obesity...
  3. ncbi Prevention and reversal of diet-induced leptin resistance with a sugar-free diet despite high fat content
    Alexandra Shapiro
    Department of Pharmacology and Therapeutics, University of Florida, College of Medicine, Box 100267, Gainesville, FL 32610, USA
    Br J Nutr 106:390-7. 2011
    ..These data suggest that fructose is the bioactive component of a HF/high-sugar diet that is essential for the induction of leptin resistance...
  4. ncbi POMC overexpression in the ventral tegmental area ameliorates dietary obesity
    Lourdes M Andino
    Departments of Pharmacology and Therapeutics Aging and Geriatrics, University of Florida College of Medicine, PO Box 100267, Gainesville, Florida 32610, USA
    J Endocrinol 210:199-207. 2011
    ..In conclusion, these data indicate a role for POMC overexpression within the VTA reward center to combat HF-induced obesity...
  5. ncbi Central overexpression of leptin antagonist reduces wheel running and underscores importance of endogenous leptin receptor activity in energy homeostasis
    Michael Matheny
    Department of Pharmacology and Therapeutic, University of Florida College of Medicine, Gainesville, Florida 32610, USA
    Am J Physiol Regul Integr Comp Physiol 297:R1254-61. 2009
    ..These findings underscore the critical role of unrestrained leptin receptor activity in long-term energy homeostasis and suggest that even minor disruption of leptin receptor function can promote obesity...
  6. ncbi Synergy between leptin therapy and a seemingly negligible amount of voluntary wheel running prevents progression of dietary obesity in leptin-resistant rats
    Alexandra Shapiro
    Department of Pharmacology and Therapeutics, Box 100267, University of Florida College of Medicine, Gainesville, Florida 32610, USA
    Diabetes 57:614-22. 2008
    ..Second, we examined if voluntary wheel running is beneficial in reducing the trajectory of weight gain in high-fat-raised leptin-resistant rats...
  7. ncbi Molecular and biological characterization of a Cypovirus from the mosquito Culex restuans
    Terry B Green
    ARS, CMAVE, Gainesville, FL 32608, USA
    J Invertebr Pathol 91:27-34. 2006
    ..Therefore, we propose that CrCPV is a member of the Cypovirus-17 group and designate this species as CrCPV-17...
  8. ncbi Morphological and molecular characterization of a Cypovirus (Reoviridae) from the mosquito Uranotaenia sapphirina (Diptera: Culicidae)
    Alexandra Shapiro
    Center for Medical, Agricultural and Veterinary Entomology, USDA/ARS, Gainesville, FL 32604, USA
    J Virol 79:9430-8. 2005
    ..We conclude that UsCPV should be recognized as a member of a new Cypovirus species (Cypovirus 17, strain UsCPV-17)...