Affiliation: University of Louisville
Shao H, Sun D, Sun S, Cruze J, Bora N, Kaplan H. Expression of B7 molecules in the eye during experimental autoimmune anterior uveitis (EAAU). Curr Eye Res. 2002;25:271-7 pubmed
..B7.1 and B7.2 are expressed in the eye at different times during EAAU. Both B7 molecules are required for the induction of EAAU, although they probably have different roles. ..
Jiang G, Sun D, Yang H, Lu Q, Kaplan H, Shao H. HMGB1 is an early and critical mediator in an animal model of uveitis induced by IRBP-specific T cells. J Leukoc Biol. 2014;95:599-607 pubmed publisher
..Our study demonstrates that HMGB1 is an early and critical mediator of ocular inflammation initiated by autoreactive T cell invasion. ..
Jiang G, Wang Y, Yun J, Hajrasouliha A, Zhao Y, Sun D, et al
. HMGB1 release triggered by the interaction of live retinal cells and uveitogenic T cells is Fas/FasL activation-dependent. J Neuroinflammation. 2015;12:179 pubmed publisher
..Our results show that interaction of retinal cells with infiltrating uveitogenic T cells leads to rapid release of HMGB1 via the Fas/FasL inflammatory signaling pathway. ..
Ke Y, Sun D, Jiang G, Kaplan H, Shao H. PD-L1(hi) retinal pigment epithelium (RPE) cells elicited by inflammatory cytokines induce regulatory activity in uveitogenic T cells. J Leukoc Biol. 2010;88:1241-9 pubmed publisher