Mahnaz Shahidi

Summary

Affiliation: University of Illinois at Chicago
Country: USA

Publications

  1. ncbi request reprint A method for differentiating ocular higher-order aberrations from light scatter applied to retinitis pigmentosa
    Mahnaz Shahidi
    Department of Ophthalmology and Visual Sciences, University of Illinois at Chicago, Chicago, Illinois 60612, USA
    Optom Vis Sci 82:976-80. 2005
  2. pmc A method for chorioretinal oxygen tension measurement
    Mahnaz Shahidi
    Department of Ophthalmology and Visual Sciences, University of Illinois at Chicago, Chicago, Illinois 60612, USA
    Curr Eye Res 31:357-66. 2006
  3. pmc Quantitative assessment of conjunctival microvascular circulation of the human eye
    M Shahidi
    Department of Ophthalmology and Visual Sciences, University of Illinois at Chicago, Chicago, IL 60612, USA
    Microvasc Res 79:109-13. 2010
  4. ncbi request reprint Quantitative thickness measurement of retinal layers imaged by optical coherence tomography
    Mahnaz Shahidi
    Department of Ophthalmology and Visual Sciences, University of Illinois at Chicago, 1855 West Taylor Street, Chicago, IL 60612, USA
    Am J Ophthalmol 139:1056-61. 2005
  5. ncbi request reprint Optical section retinal imaging and wavefront sensing in diabetes
    Mahnaz Shahidi
    Department of Ophthalmology and Visual Sciences, University of Illinois at Chicago, Chicago, Illinois 60612, USA
    Optom Vis Sci 81:778-84. 2004
  6. ncbi request reprint Measurements of ocular aberrations and light scatter in healthy subjects
    Mahnaz Shahidi
    Department of Ophthalmology and Visual Sciences, University of Illinois at Chicago, Chicago, Illinois 60612, USA
    Optom Vis Sci 81:853-7. 2004
  7. pmc Three-dimensional mapping of chorioretinal vascular oxygen tension in the rat
    Mahnaz Shahidi
    Department of Ophthalmology and Visual Sciences, University of Illinois at Chicago, Chicago, Illinois 60612, USA
    Invest Ophthalmol Vis Sci 50:820-5. 2009
  8. pmc Retinal tissue oxygen tension imaging in the rat
    Mahnaz Shahidi
    Department of Ophthalmology and Visual Sciences, University of Illinois at Chicago, Chicago, Illinois 60612, USA
    Invest Ophthalmol Vis Sci 51:4766-70. 2010
  9. pmc Abnormal retinal vascular oxygen tension response to light flicker in diabetic rats
    Norman P Blair
    Department of Ophthalmology and Visual Sciences University of Illinois at Chicago, Chicago, Illinois 60612, USA
    Invest Ophthalmol Vis Sci 50:5444-8. 2009
  10. pmc Inner retinal oxygen extraction fraction in rat
    Pang yu Teng
    Department of Ophthalmology and Visual Sciences, University of Illinois at Chicago, USA
    Invest Ophthalmol Vis Sci 54:647-51. 2013

Research Grants

  1. Retinal Image Quality in Retinal-diseased Eyes
    Mahnaz Shahidi; Fiscal Year: 2010
  2. Noninvasive Imaging of Chorioretinal Oxygen Tension
    Mahnaz Shahidi; Fiscal Year: 2007
  3. Noninvsive Imaging of Chorio-retinal Oxygen Tension
    Mahnaz Shahidi; Fiscal Year: 2005
  4. Retinal Image Quality in Retinal-diseased Eyes
    Mahnaz Shahidi; Fiscal Year: 2004
  5. Noninvasive Imaging of Chorioretinal Oxygen Tension
    Mahnaz Shahidi; Fiscal Year: 2010

Collaborators

Detail Information

Publications42

  1. ncbi request reprint A method for differentiating ocular higher-order aberrations from light scatter applied to retinitis pigmentosa
    Mahnaz Shahidi
    Department of Ophthalmology and Visual Sciences, University of Illinois at Chicago, Chicago, Illinois 60612, USA
    Optom Vis Sci 82:976-80. 2005
    ..The purpose of this study is to report a method for differentiating ocular higher-order aberrations and intraocular light scatter based on a deconvolution technique...
  2. pmc A method for chorioretinal oxygen tension measurement
    Mahnaz Shahidi
    Department of Ophthalmology and Visual Sciences, University of Illinois at Chicago, Chicago, Illinois 60612, USA
    Curr Eye Res 31:357-66. 2006
    ..The feasibility of the system for the measurement of changes in pO2 separately in the retinal and choroidal vasculatures was established in rat eyes by varying the fraction of inspired oxygen and inhibiting nitric oxide activity...
  3. pmc Quantitative assessment of conjunctival microvascular circulation of the human eye
    M Shahidi
    Department of Ophthalmology and Visual Sciences, University of Illinois at Chicago, Chicago, IL 60612, USA
    Microvasc Res 79:109-13. 2010
    ..87). The application of this technique for in vivo quantitative assessment of blood flow dynamics has potential to impact diagnosis and monitoring of various cardiovascular and blood disorders...
  4. ncbi request reprint Quantitative thickness measurement of retinal layers imaged by optical coherence tomography
    Mahnaz Shahidi
    Department of Ophthalmology and Visual Sciences, University of Illinois at Chicago, 1855 West Taylor Street, Chicago, IL 60612, USA
    Am J Ophthalmol 139:1056-61. 2005
    ..To report an image analysis algorithm that was developed to provide quantitative thickness measurement of retinal layers on optical coherence tomography (OCT) images...
  5. ncbi request reprint Optical section retinal imaging and wavefront sensing in diabetes
    Mahnaz Shahidi
    Department of Ophthalmology and Visual Sciences, University of Illinois at Chicago, Chicago, Illinois 60612, USA
    Optom Vis Sci 81:778-84. 2004
    ..To investigate differences in higher-order ocular aberrations and in optical section retinal image resolution between healthy normal and diabetic subjects...
  6. ncbi request reprint Measurements of ocular aberrations and light scatter in healthy subjects
    Mahnaz Shahidi
    Department of Ophthalmology and Visual Sciences, University of Illinois at Chicago, Chicago, Illinois 60612, USA
    Optom Vis Sci 81:853-7. 2004
    ..To report and validate an optical imaging system that provides measurements of higher order ocular aberrations and light scatter in human eyes...
  7. pmc Three-dimensional mapping of chorioretinal vascular oxygen tension in the rat
    Mahnaz Shahidi
    Department of Ophthalmology and Visual Sciences, University of Illinois at Chicago, Chicago, Illinois 60612, USA
    Invest Ophthalmol Vis Sci 50:820-5. 2009
    ..An optical section phosphorescence lifetime imaging system was developed for three-dimensional mapping of oxygen tension (P(O2)) in chorioretinal vasculatures...
  8. pmc Retinal tissue oxygen tension imaging in the rat
    Mahnaz Shahidi
    Department of Ophthalmology and Visual Sciences, University of Illinois at Chicago, Chicago, Illinois 60612, USA
    Invest Ophthalmol Vis Sci 51:4766-70. 2010
    ..To report an imaging technique for measurement of oxygen tension (PO2) in retinal tissue and establish its feasibility for measuring retinal PO2 variations in rat eyes by adjusting the fraction of inspired oxygen (FiO2)...
  9. pmc Abnormal retinal vascular oxygen tension response to light flicker in diabetic rats
    Norman P Blair
    Department of Ophthalmology and Visual Sciences University of Illinois at Chicago, Chicago, Illinois 60612, USA
    Invest Ophthalmol Vis Sci 50:5444-8. 2009
    ..To test the hypothesis that the intravascular oxygen response to light flicker is abnormal in diabetes...
  10. pmc Inner retinal oxygen extraction fraction in rat
    Pang yu Teng
    Department of Ophthalmology and Visual Sciences, University of Illinois at Chicago, USA
    Invest Ophthalmol Vis Sci 54:647-51. 2013
    ..We report a method for measurement of inner retinal OEF in rats under normoxia and hypoxia based on vascular oxygen tension (PO(2)) imaging...
  11. pmc Chorioretinal vascular oxygen tension changes in response to light flicker
    Akbar Shakoor
    Department of Ophthalmology and Visual Sciences, University of Illinois at Chicago UIC, 1855 West Taylor Street, Chicago, IL 60612, USA
    Invest Ophthalmol Vis Sci 47:4962-5. 2006
    ..To investigate oxygen tension (P(O2)) changes in the retinal and choroidal vasculatures in response to visual stimulation by light flicker...
  12. ncbi request reprint Feasibility of noninvasive imaging of chorioretinal oxygenation
    Mahnaz Shahidi
    Department of Ophthalmology and Visual Sciences, University of Illinois at Chicago, Chicago, Illinois 60612, USA
    Ophthalmic Surg Lasers Imaging 35:415-22. 2004
    ..Due to its depth discrimination, this optical section imaging technique has potential for differential imaging of oxygen tension in the chorioretinal vasculatures...
  13. ncbi request reprint Noninvasive assessment of chorioretinal oxygenation changes in experimental carotid occlusion
    Akbar Shakoor
    Department of Ophthalmology and Visual Sciences, University of Illinois at Chicago, Chicago, Illinois 60612, USA
    Curr Eye Res 30:763-71. 2005
    ..To demonstrate the capability of our optical imaging system to assess oxygenation changes in chorioretinal vasculatures due to experimentally induced carotid occlusion...
  14. pmc Oxygen tension and gradient measurements in the retinal microvasculature of rats
    Pang yu Teng
    Department of Ophthalmology and Visual Sciences, University of Illinois at Chicago, 1855 West Taylor Street, Chicago, IL 60612, USA
    Graefes Arch Clin Exp Ophthalmol 250:361-7. 2012
    ..Therefore, measurements of retinal vascular oxygen tension (PO(2)) and PO(2) longitudinal gradients (gPO(2)) along retinal blood vessels may help gain fundamental knowledge of retinal physiology and pathological processes...
  15. pmc Object frequency characteristics of visual acuity
    J Jason McAnany
    Department of Ophthalmology and Visual Sciences, University of Illinois at Chicago, Chicago, Illinois 60612, USA
    Invest Ophthalmol Vis Sci 52:9534-8. 2011
    ..To examine the extent to which visual acuity (VA) for broadband optotypes is scale invariant by determining whether the same object frequencies mediate VA for individuals with different levels of VA...
  16. ncbi request reprint Is "whole eye" wavefront analysis helpful to corneal refractive therapy?
    Charlotte E Joslin
    Department of Ophthalmology and Visual Sciences, University of Illinois at Chicago, 1855 West Taylor Street, Suite 3 164, Chicago, IL 60612, USA
    Eye Contact Lens 30:186-8; discussion 205-6. 2004
    ..To examine how corneal refractive therapy (CRT) affects the balance between corneal surface and whole eye spherical aberration (Z4) and to identify whether corneal aberrations alone can accurately predict optical outcomes of CRT...
  17. ncbi request reprint Higher-order wavefront aberrations in retinitis pigmentosa
    Aruna S Rajagopalan
    Department of Ophthalmology and Visual Sciences, University of Illinois at Chicago, Chicago, Illinois 60612, USA
    Optom Vis Sci 82:623-8. 2005
    ..The purpose of this study was to characterize higher-order wavefront aberrations associated with posterior subcapsular (PSC) cataracts in patients with retinitis pigmentosa (RP)...
  18. ncbi request reprint Retinal thickness and visual thresholds measured in patients with retinitis pigmentosa
    Marsha A Apushkin
    Department of Ophthalmology and Visual Sciences, University of Illinois at Chicago, Chicago, Illinois, USA
    Retina 27:349-57. 2007
    ..To determine the association between retinal thickness and visual function in patients with retinitis pigmentosa (RP)...
  19. doi request reprint Correlation between microaneurysms and retinal thickness in diabetic macular edema
    Norman P Blair
    Department of Ophthalmology and Visual Sciences, University of Illinois, Chicago, Illinois 60612, USA
    Retina 28:1097-103. 2008
    ..The hypothesis that thicker areas of retina in diabetic retinopathy have more microaneurysms per unit area than areas that are not as thick was tested...
  20. pmc Outer retinal oxygen consumption of rat by phosphorescence lifetime imaging
    Justin Wanek
    Department of Ophthalmology and Visual Sciences, University of Illinois at Chicago, Chicago, IL 60612, USA
    Curr Eye Res 37:132-7. 2012
    ..The purpose of this study was to report measurements of Q(OR) in rats using a phosphorescence lifetime imaging technique...
  21. doi request reprint Association between retinal thickness and retinal pigment epithelium elevation in age-related macular degeneration
    Michael P Blair
    Department of Ophthalmology and Visual Sciences, University of Illinois at Chicago, Chicago, Illinois, USA
    Ophthalmic Surg Lasers Imaging 41:175-81. 2010
    ..To determine the association between retinal pigment epithelium elevation and maximum retinal thickness in patients with age-related macular degeneration...
  22. pmc Feasibility of a method for en face imaging of photoreceptor cell integrity
    Justin Wanek
    Department of Ophthalmology and Visual Sciences, University of Illinois at Chicago, Chicago, Illinois 60612, USA
    Am J Ophthalmol 152:807-14.e1. 2011
    ..To report a method for en face imaging of the photoreceptor inner and outer segment junction by spectral-domain optical coherence tomography (SD OCT) and to describe findings in normal subjects and patients with various retinal diseases...
  23. ncbi request reprint Imaging retinal depression sign in sickle cell anemia using optical coherence tomography and the retinal thickness analyzer
    Akbar Shakoor
    Department of Ophthalmology and Visual Sciences, University of Illinois at Chicago, 1855 W Taylor Street, Chicago, IL 60612, USA
    Arch Ophthalmol 123:1278-9. 2005
  24. ncbi request reprint A method for three-dimensional imaging of the retina in human eyes
    Mahnaz Shahidi
    Department of Ophthalmology and Visual Sciences, University of Illinois at Chicago, 1855 West Taylor Street, Chicago, IL 60612, USA
    Ophthalmic Surg Lasers Imaging 38:35-42. 2007
    ..An optical system for three-dimensional imaging of the retinal tissue in human eyes is described...
  25. pmc Differential macular morphology in patients with RPE65-, CEP290-, GUCY2D-, and AIPL1-related Leber congenital amaurosis
    Sirichai Pasadhika
    Department of Ophthalmology and Visual Sciences, University of Illinois Medical Center, Chicago, Illinois, USA
    Invest Ophthalmol Vis Sci 51:2608-14. 2010
    ..To evaluate genotypic and macular morphologic correlations in patients with RPE65-, CEP290-, GUCY2D-, or AIPL1-related Leber congenital amaurosis (LCA) using spectral-domain optical coherence tomography (SD-OCT)...
  26. pmc Thickness mapping of retinal layers by spectral-domain optical coherence tomography
    Ana L Loduca
    Department of Ophthalmology and Visual Sciences, University of Illinois at Chicago, Chicago, Illinois 60612, USA
    Am J Ophthalmol 150:849-55. 2010
    ..Intersubject thickness variability and thickness variations in 9 macular sectors were established...
  27. pmc Thickness profiles of retinal layers by optical coherence tomography image segmentation
    Ahmet Murat Bagci
    Department of Electrical and Computer Engineering, University of Illinois at Chicago, Chicago, Illinois, USA
    Am J Ophthalmol 146:679-87. 2008
    ..To report an image segmentation algorithm that was developed to provide quantitative thickness measurement of six retinal layers in optical coherence tomography (OCT) images...
  28. ncbi request reprint Nerve fiber layer thickness in glaucoma patients with asymmetric hemifield visual field loss
    Vandana Badlani
    Department of Ophthalmology and Visual Sciences, University of Illinois at Chicago, 60612, USA
    J Glaucoma 15:275-80. 2006
    ..To investigate the presence of retinal nerve fiber layer (RNFL) thinning and determine the relationship between RNFL thickness and visual field sensitivity loss in glaucoma patients with asymmetric hemifield visual field loss...
  29. pmc Macular thinning associated with unilateral optic nerve hypoplasia
    Quan V Hoang
    Department of Ophthalmology and Visual Sciences, University of Illinois at Chicago, Chicago, Illinois 60612, USA
    Ophthalmic Surg Lasers Imaging 42:e6-9. 2011
    ....
  30. pmc Contributions of optical and non-optical blur to variation in visual acuity
    J Jason McAnany
    Department of Ophthalmology and Visual Sciences, University of Illinois at Chicago, Chicago, Illinois, USA
    Optom Vis Sci 88:716-23. 2011
    ..To determine the relative contributions of optical and non-optical sources of intrinsic blur to variations in visual acuity (VA) among normally sighted subjects...
  31. ncbi request reprint Chorioretinal topography and histopathology in laser-induced choroidal neovascularization
    Wico W Lai
    Department of Ophthalmology and Visual Sciences, University of Illinois at Chicago, 1855 W Taylor St, Chicago, Illinois 60612, USA
    Ophthalmic Surg Lasers Imaging 34:38-43. 2003
    ..To investigate the correspondence between topographic mapping of the vitreoretinal and chorioretinal surfaces in vivo and histopathology findings...
  32. pmc Central macular splaying and outer retinal thinning in asymptomatic sickle cell patients by spectral-domain optical coherence tomography
    Quan V Hoang
    Department of Ophthalmology and Visual Sciences, University of Illinois at Chicago, 1855 W Taylor St, Chicago, IL 60612, USA
    Am J Ophthalmol 151:990-994.e1. 2011
    ..To investigate the prevalence and degree of macular thinning on optical coherence tomography (SDOCT) in African-American female patients with asymptomatic sickle cell disease...
  33. pmc Regularized estimation of retinal vascular oxygen tension from phosphorescence images
    Isa Yildirim
    Department of Electrical and Computer Engineering, University of Illinois, Chicago, IL 60607 USA
    IEEE Trans Biomed Eng 56:1989-95. 2009
    ..The method is shown to yield estimates that are robust to noise and whose variance is lower than that obtained with the classical LS method...
  34. pmc Inner retinal oxygen delivery and metabolism under normoxia and hypoxia in rat
    Justin Wanek
    Department of Ophthalmology and Visual Sciences, University of Illinois at Chicago, Chicago, Illinois
    Invest Ophthalmol Vis Sci 54:5012-9. 2013
    ..We report measurements of oxygen delivery by the retinal circulation (DO2_IR) and inner retinal oxygen metabolism (MO2_IR) under systemic normoxia and hypoxia in rat...
  35. pmc Effect of aberrations and scatter on image resolution assessed by adaptive optics retinal section imaging
    Justin M Wanek
    Department of Ophthalmology and Visual Sciences, University of Illinois at Chicago 60612, USA
    J Opt Soc Am A Opt Image Sci Vis 24:1296-304. 2007
    ..The findings of the current study suggest that AO imaging systems can potentially improve image resolution in aging eyes with increased aberrations and scatter...
  36. doi request reprint Human bulbar conjunctival hemodynamics in hemoglobin SS and SC disease
    Justin Wanek
    Department of Ophthalmology and Visual Sciences, University of Illinois at Chicago, Chicago, IL 60612, USA
    Am J Hematol 88:661-4. 2013
    ..2). Quantitative assessment of conjunctival microvascular hemodynamics in SS and SC disease may advance understanding of sickle cell disease pathophysiology and thereby improve therapeutic interventions...
  37. pmc Feasibility of conjunctival hemodynamic measurements in rabbits: reproducibility, validity, and response to acute hypotension
    Bruce Gaynes
    Department of Ophthalmology, Loyola University Medical Center, Maywood, Illinois, USA
    Microcirculation 19:521-9. 2012
    ..To evaluate the feasibility of conjunctival hemodynamic measurements based on assessment of reproducibility, validity, and response to acute hypotension...
  38. pmc Inner retinal metabolic rate of oxygen by oxygen tension and blood flow imaging in rat
    Justin Wanek
    Department of Ophthalmology and Visual Sciences, University of Illinois at Chicago, Chicago IL, 60612, USA
    Biomed Opt Express 2:2562-8. 2011
    ..The application of this technology has the potential to broaden knowledge of retinal oxygen dynamics and advance understanding of disease pathophysiology...
  39. pmc Representing the retinal line spread shape with mathematical functions
    Yi Rong Yang
    Department of Bioengineering, University of Illinois at Chicago, IL 60607, USA
    J Zhejiang Univ Sci B 9:996-1002. 2008
    ..Determining analytical functions that represent the double-pass LSF is important because it allows modeling the optical performance of the eye...
  40. ncbi request reprint Higher-order wavefront aberrations in corneal refractive therapy
    Charlotte E Joslin
    Department of Ophthalmology and Visual Sciences, University of Illinois at Chicago, 1855 W Taylor St, Suite 3 164, Chicago, IL 60612, USA
    Optom Vis Sci 80:805-11. 2003
    ..To assess the changes in higher-order (third through sixth) ocular wavefront aberrations produced by Corneal Refractive Therapy (CRT; Paragon Vision Sciences, Mesa, AZ)...
  41. ncbi request reprint Relationship of retinal structural and clinical vision parameters to driving performance of diabetic retinopathy patients
    Janet P Szlyk
    Research and Development Service, Department of Veterans Affairs Chicago Health Care System, West Side Division, Chicago, IL 60612, USA
    J Rehabil Res Dev 41:347-58. 2004
    ..Retinal thickness and laser scarring correlated with driving simulator performance in subjects with diabetic retinopathy...
  42. ncbi request reprint Relation between retinal thickening and clinically visible fundus pathologies in mild nonproliferative diabetic retinopathy
    Hirokazu Nishiwaki
    Wilmer Ophthalmological Institute, Johns Hopkins University, Baltimore, Maryland, USA
    Ophthalmic Surg Lasers 33:127-34. 2002
    ..To determine the association of retinal thickening (RT) with clinically observable retinal pathologies in eyes with mild nonproliferative diabetic retinopathy...

Research Grants11

  1. Retinal Image Quality in Retinal-diseased Eyes
    Mahnaz Shahidi; Fiscal Year: 2010
    ....
  2. Noninvasive Imaging of Chorioretinal Oxygen Tension
    Mahnaz Shahidi; Fiscal Year: 2007
    ..Once refined, the technique will serve as a valuable tool for investigating disease-related oxygen dynamics, and thereby, can significantly impact the understanding of the pathophysiology, diagnosis and treatment of retinal diseases. ..
  3. Noninvsive Imaging of Chorio-retinal Oxygen Tension
    Mahnaz Shahidi; Fiscal Year: 2005
    ..abstract_text> ..
  4. Retinal Image Quality in Retinal-diseased Eyes
    Mahnaz Shahidi; Fiscal Year: 2004
    ..abstract_text> ..
  5. Noninvasive Imaging of Chorioretinal Oxygen Tension
    Mahnaz Shahidi; Fiscal Year: 2010
    ..Once refined, the technique will serve as a valuable tool for investigating disease-related oxygen dynamics, and thereby, can significantly impact the understanding of the pathophysiology, diagnosis and treatment of retinal diseases. ..