E Shahar

Summary

Affiliation: University of Minnesota
Country: USA

Publications

  1. ncbi request reprint Docosahexaenoic acid and smoking-related chronic obstructive pulmonary disease. The Atherosclerosis Risk in Communities Study Investigators
    E Shahar
    Division of Epidemiology, School of Public Health, and Department of Laboratory Medicine and Pathology, University of Minnesota, Minneapolis, Minnesota, USA
    Am J Respir Crit Care Med 159:1780-5. 1999
  2. ncbi request reprint Plasma lipid profile and incident ischemic stroke: the Atherosclerosis Risk in Communities (ARIC) study
    Eyal Shahar
    Division of Epidemiology, University of Minnesota, 1300 South Second St, Suite 300, Minneapolis, MN 55454, USA
    Stroke 34:623-31. 2003
  3. ncbi request reprint Hormone replacement therapy and sleep-disordered breathing
    Eyal Shahar
    Division of Epidemiology, University of Minnesota, 1300 South Second Street, Suite 300, Minneapolis, MN 55454, USA
    Am J Respir Crit Care Med 167:1186-92. 2003
  4. ncbi request reprint Generalizability: beyond plausibility and handwaving
    Eyal Shahar
    Division of Epidemiology, University of Minnesota, Minneapolis, MN 55454, USA
    J Eval Clin Pract 9:151-9. 2003
  5. ncbi request reprint Trends in acute coronary heart disease mortality, morbidity, and medical care from 1985 through 1997: the Minnesota heart survey
    P G McGovern
    Division of Epidemiology, School of Public Health, University of Minnesota, Minneapolis, USA
    Circulation 104:19-24. 2001
  6. ncbi request reprint Stroke rates during the 1980s. The Minnesota Stroke Survey
    E Shahar
    Division of Epidemiology, School of Public Health, University of Minnesota, Minneapolis 55454 1015, USA
    Stroke 28:275-9. 1997
  7. ncbi request reprint Sleep-disordered breathing and cardiovascular disease: cross-sectional results of the Sleep Heart Health Study
    E Shahar
    Division of Epidemiology, School of Public Health, University of Minnesota, Minneapolis, Minnesota, USA
    Am J Respir Crit Care Med 163:19-25. 2001
  8. ncbi request reprint Familial history of stroke and stroke risk. The Family Heart Study
    D Liao
    Department of Epidemiology, School of Public Health, University of North Carolina at Chapel Hill 27514, USA
    Stroke 28:1908-12. 1997
  9. ncbi request reprint White blood cell count and incidence of coronary heart disease and ischemic stroke and mortality from cardiovascular disease in African-American and White men and women: atherosclerosis risk in communities study
    C D Lee
    Division of Epidemiology, School of Public Health, University of Minnesota, Minneapolis, 55454-1015, USA
    Am J Epidemiol 154:758-64. 2001
  10. pmc Asthma and incident cardiovascular disease: the Atherosclerosis Risk in Communities Study
    J G Schanen
    University of Minnesota, School of Public Health, Division of Epidemiology and Community Health, 1300 South 2nd Street, Suite 300, Minneapolis, MN 55454, USA
    Thorax 60:633-8. 2005

Research Grants

  1. COMMUNITY SURVEILLANCE OF CONGESTIVE HEART FAILURE
    Eyal Shahar; Fiscal Year: 2002
  2. Sleep Heart Health Study (SHHS)
    Eyal Shahar; Fiscal Year: 2007

Collaborators

Detail Information

Publications46

  1. ncbi request reprint Docosahexaenoic acid and smoking-related chronic obstructive pulmonary disease. The Atherosclerosis Risk in Communities Study Investigators
    E Shahar
    Division of Epidemiology, School of Public Health, and Department of Laboratory Medicine and Pathology, University of Minnesota, Minneapolis, Minnesota, USA
    Am J Respir Crit Care Med 159:1780-5. 1999
    ..DHA may have a role in preventing or treating COPD and other chronic inflammatory conditions of the lung. Pilot testing of that hypothesis in experimental models seems warranted...
  2. ncbi request reprint Plasma lipid profile and incident ischemic stroke: the Atherosclerosis Risk in Communities (ARIC) study
    Eyal Shahar
    Division of Epidemiology, University of Minnesota, 1300 South Second St, Suite 300, Minneapolis, MN 55454, USA
    Stroke 34:623-31. 2003
    ..The role of circulating lipids and lipoproteins in the pathogenesis of ischemic stroke remains uncertain despite 3 decades of research. We examined this issue in a large population-based cohort...
  3. ncbi request reprint Hormone replacement therapy and sleep-disordered breathing
    Eyal Shahar
    Division of Epidemiology, University of Minnesota, 1300 South Second Street, Suite 300, Minneapolis, MN 55454, USA
    Am J Respir Crit Care Med 167:1186-92. 2003
    ..36; 95% confidence interval, 0.21 to 0.60). If the observed associations are causal, hormone replacement therapy could have a role in preventing or alleviating sleep-disordered breathing...
  4. ncbi request reprint Generalizability: beyond plausibility and handwaving
    Eyal Shahar
    Division of Epidemiology, University of Minnesota, Minneapolis, MN 55454, USA
    J Eval Clin Pract 9:151-9. 2003
    ....
  5. ncbi request reprint Trends in acute coronary heart disease mortality, morbidity, and medical care from 1985 through 1997: the Minnesota heart survey
    P G McGovern
    Division of Epidemiology, School of Public Health, University of Minnesota, Minneapolis, USA
    Circulation 104:19-24. 2001
    ..Coronary heart disease (CHD) mortality continued to decline from 1985 to 1997...
  6. ncbi request reprint Stroke rates during the 1980s. The Minnesota Stroke Survey
    E Shahar
    Division of Epidemiology, School of Public Health, University of Minnesota, Minneapolis 55454 1015, USA
    Stroke 28:275-9. 1997
    ..In the present study, we examined trends in the rate of hospitalized stroke in Minneapolis/ St Paul between 1980 and 1990...
  7. ncbi request reprint Sleep-disordered breathing and cardiovascular disease: cross-sectional results of the Sleep Heart Health Study
    E Shahar
    Division of Epidemiology, School of Public Health, University of Minnesota, Minneapolis, Minnesota, USA
    Am J Respir Crit Care Med 163:19-25. 2001
    ..99-1.62), respectively. These findings are compatible with modest to moderate effects of sleep-disordered breathing on heterogeneous manifestations of CVD within a range of AHI values that are considered normal or only mildly elevated...
  8. ncbi request reprint Familial history of stroke and stroke risk. The Family Heart Study
    D Liao
    Department of Epidemiology, School of Public Health, University of North Carolina at Chapel Hill 27514, USA
    Stroke 28:1908-12. 1997
    ....
  9. ncbi request reprint White blood cell count and incidence of coronary heart disease and ischemic stroke and mortality from cardiovascular disease in African-American and White men and women: atherosclerosis risk in communities study
    C D Lee
    Division of Epidemiology, School of Public Health, University of Minnesota, Minneapolis, 55454-1015, USA
    Am J Epidemiol 154:758-64. 2001
    ..An elevated WBC count is directly associated with increased incidence of coronary heart disease and ischemic stroke and mortality from cardiovascular disease in African-American and White men and women...
  10. pmc Asthma and incident cardiovascular disease: the Atherosclerosis Risk in Communities Study
    J G Schanen
    University of Minnesota, School of Public Health, Division of Epidemiology and Community Health, 1300 South 2nd Street, Suite 300, Minneapolis, MN 55454, USA
    Thorax 60:633-8. 2005
    ..A possible association between asthma and cardiovascular disease has been described in several exploratory studies...
  11. ncbi request reprint Ethnic differences in coronary calcification: the Multi-Ethnic Study of Atherosclerosis (MESA)
    Diane E Bild
    Division of Epidemiology and Clinical Applications, National Heart, Lung, and Blood Institute, Bethesda, MD, USA
    Circulation 111:1313-20. 2005
    ....
  12. ncbi request reprint Serum uric acid and risk of ischemic stroke: the ARIC Study
    Atsushi Hozawa
    Division of Epidemiology and Community Health, School of Public Health, University of Minnesota, 1300 South 2nd Street, Suite 300, Minneapolis, MN 55454 1015, USA
    Atherosclerosis 187:401-7. 2006
    ..We therefore investigated the relation between UA and ischemic stroke in the Atherosclerosis Risk in Communities (ARIC) Study...
  13. ncbi request reprint Polysomnographic predictors of blood pressure and hypertension: is one index best?
    Susan Redline
    Case Western Reserve University, Cleveland, OH, USA
    Sleep 28:1122-30. 2005
    ..This study addresses the relative merits of using alternative polysomnography indexes by characterizing the consistency and strength of the association of each index with blood pressure and hypertension...
  14. doi request reprint Novel metabolic risk factors for incident heart failure and their relationship with obesity: the MESA (Multi-Ethnic Study of Atherosclerosis) study
    Hossein Bahrami
    Cardiology Division, Department of Medicine, School of Public Health, Johns Hopkins University, Baltimore, Maryland 21205, USA
    J Am Coll Cardiol 51:1775-83. 2008
    ....
  15. ncbi request reprint Physical activity and breast cancer incidence in middle-aged women: a prospective cohort study
    Amy J Mertens
    Division of Epidemiology and Community Health, University of Minnesota, Minneapolis, MN 55454, USA
    Breast Cancer Res Treat 97:209-14. 2006
    ..31 (95% CI=0.87-1.96) for the sport index and 0.87 (95% CI=0.61-1.24) for the work index. Our findings do not corroborate the majority of previous reports, which implicated physical inactivity as a risk factor for breast cancer...
  16. pmc Association of nocturnal arrhythmias with sleep-disordered breathing: The Sleep Heart Health Study
    Reena Mehra
    Department of Medicine and Pediatrics, Case Western Reserve University, Cleveland, OH 44106, USA
    Am J Respir Crit Care Med 173:910-6. 2006
    ..Sleep-disordered breathing recurrent intermittent hypoxia and sympathetic nervous system activity surges provide the milieu for cardiac arrhythmia development...
  17. ncbi request reprint Coronary risk factors and myocardial perfusion in asymptomatic adults: the Multi-Ethnic Study of Atherosclerosis (MESA)
    Lu Wang
    Division of Epidemiology, School of Public Health, School of Medicine, University of Minnesota, Minneapolis, Minnesota, USA
    J Am Coll Cardiol 47:565-72. 2006
    ..The purpose of this study was to determine the cross-sectional relation between myocardial perfusion and coronary heart disease (CHD) risk factors among adults with no clinical CHD...
  18. ncbi request reprint Prognostic value of a novel classification scheme for heart failure: the Minnesota Heart Failure Criteria
    Joseph Kim
    Medical Statistics Unit, London School of Hygiene and Tropical Medicine, University of London, UK
    Am J Epidemiol 164:184-93. 2006
    ..They closely approximate a nearly full version of the Framingham Criteria but require many fewer variables and can facilitate epidemiologic case-finding for heart failure...
  19. ncbi request reprint Risk factors for ischemic stroke subtypes: the Atherosclerosis Risk in Communities study
    Tetsuya Ohira
    Division of Epidemiology and Community Health, School of Public Health, University of Minnesota, 1300 S 2nd St, Minneapolis, MN 55454 1015, USA
    Stroke 37:2493-8. 2006
    ..To evaluate risk factors for ischemic stroke by its subtypes may contribute to more effective prevention of ischemic stroke, but few prospective studies have characterized risk factors for specific subtypes of ischemic stroke...
  20. doi request reprint Association of restless legs syndrome and cardiovascular disease in the Sleep Heart Health Study
    John W Winkelman
    Division of Sleep Medicine, Brigham and Women s Hospital, Harvard Medical School, 1505 Commonwealth Avenue, Brighton, MA 02135, USA
    Neurology 70:35-42. 2008
    ..We evaluated the cross-sectional association between restless legs syndrome (RLS) and prevalent cardiovascular disease (CVD) in a large community-based sample of middle-aged and elderly subjects...
  21. ncbi request reprint Lung function and ischemic stroke incidence: the Atherosclerosis Risk in Communities study
    Atsushi Hozawa
    Division of Epidemiology and Community Health, School of Public Health, University of Minnesota, 1300 South Second Street, Suite 300, Minneapolis, MN 55454 1015, USA
    Chest 130:1642-9. 2006
    ..Few studies have examined the relation between lung function and ischemic stroke incidence; none have studied African Americans...
  22. ncbi request reprint Association of physical activity with sleep-disordered breathing
    Stuart F Quan
    Arizona Respiratory Center, University of Arizona Health Sciences Center, 1501 N Campbell, Tucson, AZ 85724, USA
    Sleep Breath 11:149-57. 2007
    ..A program of regular vigorous physical activity of at least 3 h per week may be a useful adjunctive treatment modality for SDB, but this association needs confirmation with a prospective clinical trial...
  23. pmc Hemostatic and inflammatory risk factors for intracerebral hemorrhage in a pooled cohort
    Jared D Sturgeon
    Division of Epidemiology and Community Health, School of Public Health, University of Minnesota, 1300 S Second St, Minneapolis, MN 55454 1015, USA
    Stroke 39:2268-73. 2008
    ..The purpose of this study was to identify novel risk factors for intracerebral hemorrhagic stroke (ICH)...
  24. ncbi request reprint Sleep-disordered breathing, glucose intolerance, and insulin resistance: the Sleep Heart Health Study
    Naresh M Punjabi
    Division of Pulmonary and Critical Care Medicine, School of Medicine, Johns Hopkins University, Baltimore, MD21224, USA
    Am J Epidemiol 160:521-30. 2004
    ..The results of this study suggest that SDB is independently associated with glucose intolerance and insulin resistance and may lead to type 2 diabetes mellitus...
  25. ncbi request reprint B-mode ultrasound-detected carotid artery lesions with and without acoustic shadowing and their association with markers of inflammation and endothelial activation: the atherosclerosis risk in communities study
    Kelly J Hunt
    CVD Program, Department of Epidemiology, School of Public Health, University of North Carolina, 137 E Franklin St, Bank of America, Suite 306, Chapel Hill, NC, USA
    Atherosclerosis 162:145-55. 2002
    ..38 (95% CI: 1.10, 1.74)], a marker of endothelial activation. Associations with endothelial adhesion molecules were inconsistent. Further studies aimed at elucidating the mechanisms of arterial mineralization are warranted...
  26. ncbi request reprint Predictors of sleep-disordered breathing in community-dwelling adults: the Sleep Heart Health Study
    Terry Young
    Department of Population Health Sciences, University of Wisconsin, Madison, WI, USA
    Arch Intern Med 162:893-900. 2002
    ..Information on demographic patterns of SDB occurrence and its predictive factors in the general population is needed to target high-risk groups that may benefit from diagnosis...
  27. ncbi request reprint Serum insulin and glucose levels and breast cancer incidence: the atherosclerosis risk in communities study
    Pamela J Mink
    Division of Cancer Prevention and Division of Cancer Epidemiology and Genetics, National Cancer Institute, Rockville, MD 20852, USA
    Am J Epidemiol 156:349-52. 2002
    ..39, 95% confidence interval: 0.86, 2.23). Circulating insulin levels were not predictive of future breast cancer incidence, but there may be a weak association with type 2 diabetes, perhaps modulated via increased adiposity...
  28. ncbi request reprint Measures of cognitive function in persons with varying degrees of sleep-disordered breathing: the Sleep Heart Health Study
    Lori L Boland
    Division of Epidemiology, School of Public Health, University of Minnesota, Minneapolis, MN 55454, USA
    J Sleep Res 11:265-72. 2002
    ..In this sample of free-living individuals with mostly mild to moderate levels of SDB, the degree of SDB appeared to be unrelated to three measures of cognitive performance...
  29. ncbi request reprint Fifteen-year trends in cardiovascular risk factors (1980-1982 through 1995-1997): the Minnesota Heart Survey
    Donna K Arnett
    Division of Epidemiology, School of Public Health, University of Minnesota, Minneapolis, MN 55454 1015, USA
    Am J Epidemiol 156:929-35. 2002
    ..Paul from 1980-1982 to 1995-1997 were paralleled by less favorable recent trends in total cholesterol, hypercholesterolemia, adiposity, and physical activity...
  30. ncbi request reprint Risk factors for intracerebral hemorrhage in a pooled prospective study
    Jared D Sturgeon
    Division of Epidemiology and Community Health, School of Public Health, University of Minnesota, 1300 S Second Street, Suite 300, Minneapolis, MN 55454 1015, USA
    Stroke 38:2718-25. 2007
    ..We studied risk factors for ICH in a pooled cohort of the Atherosclerosis Risk in Communities Study (ARIC) and the Cardiovascular Health Study (CHS)...
  31. ncbi request reprint Diabetes and sleep disturbances: findings from the Sleep Heart Health Study
    Helaine E Resnick
    MedStar Research Institute, Hyattsville, Maryland 20783, USA
    Diabetes Care 26:702-9. 2003
    ..To test the hypothesis that diabetes is independently associated with sleep-disordered breathing (SDB), and in particular that diabetes is associated with sleep abnormalities of a central, rather than obstructive, nature...
  32. ncbi request reprint On morality and logic in medical practice: commentary on 'A critical appraisal of evidence-based medicine: some ethical considerations' (Gupta 2003; Journal of Evaluation in Clinical Practice 9, 111-121)
    Eyal Shahar
    School of Public Health, University of Minnesota, Minneapolis, USA
    J Eval Clin Pract 9:133-5. 2003
  33. ncbi request reprint Associations of whole-grain, refined-grain, and fruit and vegetable consumption with risks of all-cause mortality and incident coronary artery disease and ischemic stroke: the Atherosclerosis Risk in Communities (ARIC) Study
    Lyn M Steffen
    Division of Epidemiology, University of Minnesota School of Public Health, Minneapolis, 55454, USA
    Am J Clin Nutr 78:383-90. 2003
    ..However, the findings were inconsistent for fruit and vegetable intake...
  34. ncbi request reprint Glycaemia (haemoglobin A1c) and incident ischaemic stroke: the Atherosclerosis Risk in Communities (ARIC) Study
    Elizabeth Selvin
    Department of Epidemiology, Welch Center for Prevention, Epidemiology, and Clinical Research, Johns Hopkins Bloomberg School of Public Health, Baltimore, MD 21205 2223, USA
    Lancet Neurol 4:821-6. 2005
    ..Haemoglobin A1c (HbA(1c)), a measure of long-term glycaemia, is strongly related to retinopathy, nephropathy, and neuropathy in diabetes. We sought to assess the association between HbA(1c) and stroke in people with and without diabetes...
  35. ncbi request reprint Sleep and reported daytime sleepiness in normal subjects: the Sleep Heart Health Study
    Joyce A Walsleben
    Department of Pulmonary and Critical Care, New York University School of Medicine, USA
    Sleep 27:293-8. 2004
    ..To describe the distribution of nocturnal sleep characteristics and reports of daytime sleepiness in a large well-defined group of healthy adults...
  36. ncbi request reprint Sleep-disordered breathing is not associated with the presence of retinal microvascular abnormalities: the Sleep Heart Health Study
    Lori L Boland
    Division of Epidemiology, School of Public Health, University of Minnesota, Minneapolis, MN 55454 1015, USA
    Sleep 27:467-73. 2004
    ..We examined the relation between SDB and retinal microvascular abnormalities...
  37. ncbi request reprint Prediction of ischemic stroke risk in the Atherosclerosis Risk in Communities Study
    Lloyd E Chambless
    Department of Biostatistics, School of Public Health, University of North Carolina, Chapel Hill, NC 27514 4145, USA
    Am J Epidemiol 160:259-69. 2004
    ..79 to 0.83 to 0.84; for men, it went from 0.76 to 0.78 to 0.80. These modest improvements are not enough to influence clinical and public health efforts to reduce the community burden of IS...
  38. doi request reprint Baldness and myocardial infarction in men: the atherosclerosis risk in communities study
    Eyal Shahar
    Division of Epidemiology and Biostatistics, Mel and Enid Zuckerman College of Public Health, University of Arizona, Tucson, AZ 85724, USA
    Am J Epidemiol 167:676-83. 2008
    ..The results of this study suggest that male pattern baldness is not a surrogate measure of an important risk factor for myocardial infarction or asymptomatic atherosclerosis...
  39. ncbi request reprint Estimating causal parameters without target populations
    Eyal Shahar
    Division of Epidemiology and Biostatistics, Mel and Enid Zuckerman College of Public Health, University of Arizona, Tucson, AZ 85724, USA
    J Eval Clin Pract 13:814-6. 2007
    ..Some methods to adjust for confounders heavily draw upon this idea...
  40. pmc HDL-cholesterol and incidence of breast cancer in the ARIC cohort study
    Anna M Kucharska-Newton
    Department of Epidemiology, University of North Carolina at Chapel Hill, NC, USA
    Ann Epidemiol 18:671-7. 2008
    ..S. communities...
  41. ncbi request reprint Relation of sleep-disordered breathing to carotid plaque and intima-media thickness
    Keattiyoat Wattanakit
    Division of Epidemiology and Community Health, School of Public Health, University of Minnesota, Suite 300, 1300 South 2nd Street, Minneapolis, MN 55454, United States
    Atherosclerosis 197:125-31. 2008
    ..Sleep-disordered breathing (SDB) is associated with clinical cardiovascular disease (CVD), but its relation to subclinical atherosclerosis remains to be determined...
  42. pmc Coronary artery calcification and myocardial perfusion in asymptomatic adults: the MESA (Multi-Ethnic Study of Atherosclerosis)
    Lu Wang
    Division of Epidemiology, School of Public Health, University of Minnesota, Minneapolis, Minnesota, USA
    J Am Coll Cardiol 48:1018-26. 2006
    ..This study assessed the cross-sectional association between coronary artery calcification (CAC) and myocardial perfusion in an asymptomatic population...
  43. pmc Retinal vascular caliber, cardiovascular risk factors, and inflammation: the multi-ethnic study of atherosclerosis (MESA)
    Tien Yin Wong
    Centre for Eye Research Australia, University of Melbourne, Melbourne, Australia
    Invest Ophthalmol Vis Sci 47:2341-50. 2006
    ..To describe the relationship of retinal arteriolar and venular caliber with cardiovascular risk factors, including inflammatory biomarkers, in a multiethnic population of whites, blacks, Hispanics, and Chinese...
  44. ncbi request reprint Case definitions for acute coronary heart disease in epidemiology and clinical research studies: a statement from the AHA Council on Epidemiology and Prevention; AHA Statistics Committee; World Heart Federation Council on Epidemiology and Prevention; the
    Russell V Luepker
    Circulation 108:2543-9. 2003
  45. ncbi request reprint Hospitalized heart failure: rates and long-term mortality
    Eyal Shahar
    Division of Epidemiology, School of Public Health, University of Minnesota, Minneapolis 55454, USA
    J Card Fail 10:374-9. 2004
    ..Heart failure has been called the "new epidemic of cardiovascular disease," but few studies have described key epidemiologic measures of the syndrome in geographically defined US populations...
  46. ncbi request reprint Sleep and sleep-disordered breathing in adults with predominantly mild obstructive airway disease
    Mark H Sanders
    Division of Pulmonary, Allergy, and Critical Care Medicine, Montefiore University Hospital, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania 15213, USA
    Am J Respir Crit Care Med 167:7-14. 2003
    ....

Research Grants5

  1. COMMUNITY SURVEILLANCE OF CONGESTIVE HEART FAILURE
    Eyal Shahar; Fiscal Year: 2002
    ..The investigators point out that the results of the proposed surveillance will provide guidance to public health decisions, broader surveillance projects of CHF, and a sensitive gauge of the success of medical efforts. ..
  2. Sleep Heart Health Study (SHHS)
    Eyal Shahar; Fiscal Year: 2007
    ..Accomplishing these goals will provide important information concerning the public health impact of SDB. ..