Andrey A Shabalin

Summary

Affiliation: University of North Carolina
Country: USA

Publications

  1. pmc Matrix eQTL: ultra fast eQTL analysis via large matrix operations
    Andrey A Shabalin
    Department of Biostatistics, University of North Carolina at Chapel Hill, Chapel Hill, NC 27599, USA
    Bioinformatics 28:1353-8. 2012
  2. doi request reprint Merging two gene-expression studies via cross-platform normalization
    Andrey A Shabalin
    Department of Statistics and Operations Research, University of North Carolina at Chapel Hill, NC, USA
    Bioinformatics 24:1154-60. 2008
  3. pmc FastMap: fast eQTL mapping in homozygous populations
    Daniel M Gatti
    Department of Environmental Sciences and Engineering, University of North Carolina, Chapel Hill, North Carolina 27599, USA
    Bioinformatics 25:482-9. 2009
  4. pmc Sex-specific gene expression in the BXD mouse liver
    Daniel M Gatti
    Department of Environmental Sciences and Engineering, University of North Carolina, Chapel Hill, North Carolina 27599, USA
    Physiol Genomics 42:456-68. 2010
  5. pmc Computational tools for discovery and interpretation of expression quantitative trait loci
    Fred A Wright
    Department of Biostatistics, University of North Carolina, Chapel Hill, NC 27599, USA
    Pharmacogenomics 13:343-52. 2012
  6. pmc seeQTL: a searchable database for human eQTLs
    Kai Xia
    Department of Biostatistics, University of North Carolina, Chapel Hill, NC 27599, USA
    Bioinformatics 28:451-2. 2012
  7. pmc Basal-like Breast cancer DNA copy number losses identify genes involved in genomic instability, response to therapy, and patient survival
    Victor J Weigman
    Bioinformatics and Computational Biology Program, University of North Carolina, Chapel Hill, NC 27599, USA
    Breast Cancer Res Treat 133:865-80. 2012
  8. pmc The Set2/Rpd3S pathway suppresses cryptic transcription without regard to gene length or transcription frequency
    Colin R Lickwar
    Curriculum in Genetics and Molecular Biology, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, United States of America
    PLoS ONE 4:e4886. 2009

Collaborators

Detail Information

Publications8

  1. pmc Matrix eQTL: ultra fast eQTL analysis via large matrix operations
    Andrey A Shabalin
    Department of Biostatistics, University of North Carolina at Chapel Hill, Chapel Hill, NC 27599, USA
    Bioinformatics 28:1353-8. 2012
    ..As more transcripts and SNPs get interrogated over a growing number of samples, the demand for faster tools for eQTL analysis grows stronger...
  2. doi request reprint Merging two gene-expression studies via cross-platform normalization
    Andrey A Shabalin
    Department of Statistics and Operations Research, University of North Carolina at Chapel Hill, NC, USA
    Bioinformatics 24:1154-60. 2008
    ..This article considers the problem of how to merge datasets arising from different gene-expression studies of a common organism and phenotype. Of particular interest is how to merge data from different technological platforms...
  3. pmc FastMap: fast eQTL mapping in homozygous populations
    Daniel M Gatti
    Department of Environmental Sciences and Engineering, University of North Carolina, Chapel Hill, North Carolina 27599, USA
    Bioinformatics 25:482-9. 2009
    ..However, existing eQTL mapping software does not scale well when the number of transcripts and markers are on the order of 10(5) and 10(5)-10(6), respectively...
  4. pmc Sex-specific gene expression in the BXD mouse liver
    Daniel M Gatti
    Department of Environmental Sciences and Engineering, University of North Carolina, Chapel Hill, North Carolina 27599, USA
    Physiol Genomics 42:456-68. 2010
    ..This study enhances our understanding of sex differences at the genome level and between species, as well as increasing our knowledge of the molecular underpinnings of sex differences in responses to xenobiotics...
  5. pmc Computational tools for discovery and interpretation of expression quantitative trait loci
    Fred A Wright
    Department of Biostatistics, University of North Carolina, Chapel Hill, NC 27599, USA
    Pharmacogenomics 13:343-52. 2012
    ..The purpose of this review is to help investigators find appropriate programs for eQTL analysis and interpretation...
  6. pmc seeQTL: a searchable database for human eQTLs
    Kai Xia
    Department of Biostatistics, University of North Carolina, Chapel Hill, NC 27599, USA
    Bioinformatics 28:451-2. 2012
    ..The database presents eQTL association results in a convenient browser, using both segmented local-association plots and genome-wide Manhattan plots...
  7. pmc Basal-like Breast cancer DNA copy number losses identify genes involved in genomic instability, response to therapy, and patient survival
    Victor J Weigman
    Bioinformatics and Computational Biology Program, University of North Carolina, Chapel Hill, NC 27599, USA
    Breast Cancer Res Treat 133:865-80. 2012
    ..These data suggest a possible genetic cause for genomic instability in Basal-like breast cancers and a biological rationale for the use of DNA repair inhibitor related therapeutics in this breast cancer subtype...
  8. pmc The Set2/Rpd3S pathway suppresses cryptic transcription without regard to gene length or transcription frequency
    Colin R Lickwar
    Curriculum in Genetics and Molecular Biology, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, United States of America
    PLoS ONE 4:e4886. 2009
    ..These new results and conclusions have implications for many commonly used genomic analysis approaches, and for the evolution of high-fidelity RNA polymerase II transcriptional initiation in eukaryotes...