Affiliation: University of Maryland
- Prostaglandin F2alpha receptor (FP receptor) agonists are potent adipose differentiation inhibitors for primary culture of adipocyte precursors in defined mediumG Serrero
Department of Pharmaceutical Sciences, University of Maryland School of Pharmacy, Baltimore 21201 1180, USA
Biochem Biophys Res Commun 233:200-2. 1997..In contrast compounds structurally related to PGE2 such as 17-phenyl trinor PGE2 had no effect on adipose differentiation except when added at a 10,000-fold higher concentration...
- Effect of resveratrol on the expression of autocrine growth modulators in human breast cancer cellsG Serrero
Department of Pharmaceutical Sciences, University of Maryland School of Pharmacy, Baltimore 21201, USA
Antioxid Redox Signal 3:969-79. 2001..These data suggest that resveratrol inhibits proliferation by altering autocrine growth modulator pathways in breast cancer cells...
- Mediation of estrogen mitogenic effect in human breast cancer MCF-7 cells by PC-cell-derived growth factor (PCDGF/granulin precursor)R Lu
Department of Pharmaceutical Sciences, University of Maryland School of Pharmacy, 20 North Pine Street, Baltimore, MD 21201-1180, USA
Proc Natl Acad Sci U S A 98:142-7. 2001..We conclude that autocrine PCDGF mediates the E(2) mitogenic effect via stimulation of cyclin D1. These studies provide information on estrogen action and identify an autocrine molecular target in human breast cancer cells...
- Adipose differentiation related protein: expression, purification of recombinant protein in Escherichia coli and characterization of its fatty acid binding propertiesG Serrero
Department of Pharmaceutical Sciences, University of Maryland School of Pharmacy, Baltimore, MD 21201 1180, USA
Biochim Biophys Acta 1488:245-54. 2000..The data presented here provide evidence that isolated ADRP purified in the experimental conditions described here can be used for functional studies...