Youngho Seo

Summary

Affiliation: University of California
Country: USA

Publications

  1. ncbi request reprint Correction of photon attenuation and collimator response for a body-contouring SPECT/CT imaging system
    Youngho Seo
    Department of Radiology, University of California San Francisco, 185 Berry Street, San Francisco, CA 94107 1739, USA
    J Nucl Med 46:868-77. 2005
  2. pmc In vivo tumor grading of prostate cancer using quantitative 111In-capromab pendetide SPECT/CT
    Youngho Seo
    Department of Radiology and Biomedical Imaging, University of California, San Francisco, California 94143 0946, USA
    J Nucl Med 51:31-6. 2010
  3. pmc Quantitative accuracy of PET/CT for image-based kinetic analysis
    Youngho Seo
    Center for Molecular and Functional Imaging, Department of Radiology and Biomedical Imaging, University of California, San Francisco, California 94143 0946, USA
    Med Phys 35:3086-9. 2008
  4. pmc In vivo microCT imaging of rodent cerebral vasculature
    Youngho Seo
    Center for Molecular and Functional Imaging, Department of Radiology, University of California, San Francisco, CA 94143, USA
    Phys Med Biol 53:N99-107. 2008
  5. ncbi request reprint Rodent brain imaging with SPECT/CT
    Youngho Seo
    Department of Radiology, University of California, San Francisco, California 94143, USA
    Med Phys 34:1217-20. 2007
  6. ncbi request reprint Calculation and validation of the use of effective attenuation coefficient for attenuation correction in In-111 SPECT
    Youngho Seo
    Physics Research Laboratory, Department of Radiology, University of California, San Francisco, California 94143, USA
    Med Phys 32:3628-35. 2005
  7. ncbi request reprint Progress in SPECT/CT imaging of prostate cancer
    Youngho Seo
    Department of Radiology, University of California, San Francisco, California, USA
    Technol Cancer Res Treat 5:329-36. 2006
  8. pmc Novel human single chain antibody fragments that are rapidly internalizing effectively target epithelioid and sarcomatoid mesotheliomas
    Arun K Iyer
    Center for Molecular and Functional Imaging, Department of Radiology and Biomedical Imaging, University of California, San Francisco, California, USA
    Cancer Res 71:2428-32. 2011
  9. doi request reprint Correcting tumour SUV for enhanced bone marrow uptake: retrospective 18F-FDG PET/CT studies
    Boon Keng Teo
    Department of Radiology, University of California, San Francisco, USA
    Nucl Med Commun 29:359-66. 2008
  10. ncbi request reprint Partial-volume correction in PET: validation of an iterative postreconstruction method with phantom and patient data
    Boon Keng Teo
    Department of Radiology, University of California, San Francisco, San Francisco, CA 94107, USA
    J Nucl Med 48:802-10. 2007

Research Grants

Collaborators

Detail Information

Publications26

  1. ncbi request reprint Correction of photon attenuation and collimator response for a body-contouring SPECT/CT imaging system
    Youngho Seo
    Department of Radiology, University of California San Francisco, 185 Berry Street, San Francisco, CA 94107 1739, USA
    J Nucl Med 46:868-77. 2005
    ..In this article, we evaluate a novel iterative reconstruction algorithm using the SPECT/CT data obtained from phantoms and (111)In-capromab pendetide patient studies...
  2. pmc In vivo tumor grading of prostate cancer using quantitative 111In-capromab pendetide SPECT/CT
    Youngho Seo
    Department of Radiology and Biomedical Imaging, University of California, San Francisco, California 94143 0946, USA
    J Nucl Med 51:31-6. 2010
    ..We have developed an in vivo method to quantify antibody uptake using (111)In-capromab pendetide SPECT combined with CT (SPECT/CT). Our goal was to evaluate this method for potential grading of prostate tumors...
  3. pmc Quantitative accuracy of PET/CT for image-based kinetic analysis
    Youngho Seo
    Center for Molecular and Functional Imaging, Department of Radiology and Biomedical Imaging, University of California, San Francisco, California 94143 0946, USA
    Med Phys 35:3086-9. 2008
    ..Within these constraints, the list-mode data acquired with the Biograph 16 PET/CT system are quantitatively accurate for image-based kinetic analysis...
  4. pmc In vivo microCT imaging of rodent cerebral vasculature
    Youngho Seo
    Center for Molecular and Functional Imaging, Department of Radiology, University of California, San Francisco, CA 94143, USA
    Phys Med Biol 53:N99-107. 2008
    ..g. iopromide) and therefore does not require specialized small animal specific contrast agent that has comparatively long in vivo residence time...
  5. ncbi request reprint Rodent brain imaging with SPECT/CT
    Youngho Seo
    Department of Radiology, University of California, San Francisco, California 94143, USA
    Med Phys 34:1217-20. 2007
    ..We have demonstrated a capability of imaging regions of cerebral blood flow deficit in MCAO rat brains in vivo using a pinhole SPECT dedicated to small animal imaging...
  6. ncbi request reprint Calculation and validation of the use of effective attenuation coefficient for attenuation correction in In-111 SPECT
    Youngho Seo
    Physics Research Laboratory, Department of Radiology, University of California, San Francisco, California 94143, USA
    Med Phys 32:3628-35. 2005
    ..Although these results are specific to 111In, the foundation could easily be extended to other multiple-energy isotopes...
  7. ncbi request reprint Progress in SPECT/CT imaging of prostate cancer
    Youngho Seo
    Department of Radiology, University of California, San Francisco, California, USA
    Technol Cancer Res Treat 5:329-36. 2006
    ..There were also changes in interpretations for 4 of 12 studies although the changes were not sufficient to alter prognosis or the patient treatment plan...
  8. pmc Novel human single chain antibody fragments that are rapidly internalizing effectively target epithelioid and sarcomatoid mesotheliomas
    Arun K Iyer
    Center for Molecular and Functional Imaging, Department of Radiology and Biomedical Imaging, University of California, San Francisco, California, USA
    Cancer Res 71:2428-32. 2011
    ....
  9. doi request reprint Correcting tumour SUV for enhanced bone marrow uptake: retrospective 18F-FDG PET/CT studies
    Boon Keng Teo
    Department of Radiology, University of California, San Francisco, USA
    Nucl Med Commun 29:359-66. 2008
    ..We tested this hypothesis by quantifying total F-FDG uptake in the bone marrow of patients with visibly enhanced bone marrow uptake and computing its effect on tumour SUV...
  10. ncbi request reprint Partial-volume correction in PET: validation of an iterative postreconstruction method with phantom and patient data
    Boon Keng Teo
    Department of Radiology, University of California, San Francisco, San Francisco, CA 94107, USA
    J Nucl Med 48:802-10. 2007
    ..An iterative postreconstruction method was evaluated that corrects for PVEs without a priori knowledge of tumor size or background...
  11. pmc Tumor dosimetry using [124I]m-iodobenzylguanidine microPET/CT for [131I]m-iodobenzylguanidine treatment of neuroblastoma in a murine xenograft model
    Youngho Seo
    Department of Radiology and Biomedical Imaging, University of California, San Francisco, CA 94143, USA
    Mol Imaging Biol 14:735-42. 2012
    ....
  12. pmc The effect of internalizing human single chain antibody fragment on liposome targeting to epithelioid and sarcomatoid mesothelioma
    Arun K Iyer
    Center for Molecular and Functional Imaging, Department of Radiology and Biomedical Imaging, University of California at San Francisco, San Francisco, CA 94143, USA
    Biomaterials 32:2605-13. 2011
    ....
  13. pmc Biodistributions of 177Lu- and 111In-labeled 7E11 antibodies to prostate-specific membrane antigen in xenograft model of prostate cancer and potential use of 111In-7E11 as a pre-therapeutic agent for 177Lu-7E11 radioimmunotherapy
    Mei Hsiu Pan
    Center for Molecular and Functional Imaging, Department of Radiology and Biomedical Imaging, University of California, San Francisco, CA 94143, USA
    Mol Imaging Biol 11:159-66. 2009
    ..To serve as a radioimmunotherapeutic agent, a kinetically inert conjugate is desired to maximize tumor uptake and tumor radiation dose with minimal nonspecific exposure to bone marrow and other major organs...
  14. pmc Technological development and advances in single-photon emission computed tomography/computed tomography
    Youngho Seo
    Department of Radiology, University of California, San Francisco, San Francisco, CA, USA
    Semin Nucl Med 38:177-98. 2008
    ....
  15. pmc Targeting prostate cancer cells in vivo using a rapidly internalizing novel human single-chain antibody fragment
    Jiang He
    Department of Radiology and Biomedical Imaging, Center for Molecular and Functional Imaging, University of California at San Francisco, San Francisco, California 94143, USA
    J Nucl Med 51:427-32. 2010
    ..The objective of this study was to evaluate the tumor targeting of an internalizing human antibody fragment, a small-size platform, to provide high contrast in a mouse model of human prostate carcinoma...
  16. pmc Combining dynamic and ECG-gated ⁸²Rb-PET for practical implementation in the clinic
    George A Sayre
    Department of Radiology and Biomedical Imaging, University of California, San Francisco, California 94107, USA
    Nucl Med Commun 33:4-13. 2012
    ....
  17. pmc Vorinostat increases expression of functional norepinephrine transporter in neuroblastoma in vitro and in vivo model systems
    Swati S More
    Departments of Bioengineering and Therapeutic Sciences, UCSF School of Medicine and UCSF Benioff Children s Hospital, San Francisco, California 94158, USA
    Clin Cancer Res 17:2339-49. 2011
    ....
  18. pmc Mapping of lymphatic drainage from the prostate using filtered 99mTc-sulfur nanocolloid and SPECT/CT
    Youngho Seo
    Department of Radiology and Biomedical Imaging, University of California, San Francisco, California 94107 1739, USA
    J Nucl Med 52:1068-72. 2011
    ..We have developed a practice procedure for prostate lymphoscintigraphy using SPECT/CT and filtered (99m)Tc-sulfur nanocolloid, as an alternative to the proprietary product (99m)Tc-Nanocoll, which is not approved in the United States...
  19. doi request reprint Intravenous vasopressin for the prevention of nontarget gastrointestinal embolization during liver-directed cancer treatment: experimental study in a porcine model
    Jeremy C Durack
    Department of Radiology, Memorial Sloan Kettering Cancer Center, New York, NY 10065, USA
    J Vasc Interv Radiol 23:1505-12. 2012
    ..The aim of this study was to evaluate the potential for intravenous vasopressin to reduce the risk of nontarget gastrointestinal embolization during transcatheter liver-directed cancer therapies in a porcine model...
  20. pmc Radiation dose estimation using preclinical imaging with 124I-metaiodobenzylguanidine (MIBG) PET
    Chang Lae Lee
    Department of Radiology and Biomedical Imaging, UCSF Physics Research Laboratory, University of California, San Francisco, San Francisco, California 94143, USA
    Med Phys 37:4861-7. 2010
    ..The aim of this work was to estimate human-equivalent internal radiation dose of 124I-MIBG using PET/CT data in a murine xenograft model...
  21. pmc Design and performance evaluation of a 20-aperture multipinhole collimator for myocardial perfusion imaging applications
    Jason D Bowen
    Physics Research Laboratory, Department of Radiology and Biomedical Imaging, University of California, San Francisco, CA, USA
    Phys Med Biol 58:7209-26. 2013
    ..Systematic analyses showed PH20 collimators present improved diagnostic imaging performance over LEHR collimators, requiring only collimator exchange on existing SPECT cameras for their use. ..
  22. pmc The metabolic profile of tumors depends on both the responsible genetic lesion and tissue type
    Mariia O Yuneva
    G W Hooper Research Foundation, University of California, San Francisco, San Francisco, CA 94143, USA
    Cell Metab 15:157-70. 2012
    ..Our results suggest that the metabolic profiles of tumors are likely to depend on both the genotype and tissue of origin and have implications regarding the design of therapies targeting tumor metabolism...
  23. pmc Patient-Specific Method of Generating Parametric Maps of Patlak K(i) without Blood Sampling or Metabolite Correction: A Feasibility Study
    George A Sayre
    UCSF Department of Radiology and Biomedical Imaging, University of California, San Francisco, CA 94143 0628, USA
    Int J Mol Imaging 2011:185083. 2011
    ....
  24. doi request reprint Preclinical SPECT and SPECT/CT
    Youngho Seo
    Radiological Associate of Sacramento, University of California, San Francisco, CA, USA
    Recent Results Cancer Res 187:193-220. 2013
    ..Several of these advances as well as several specific applications in oncology are highlighted and areas needing further improvement are identified...
  25. pmc Functional imaging for prostate cancer: therapeutic implications
    Carina Mari Aparici
    Department of Radiology and Biomedical Imaging, University of California, and Nuclear Medicine Service, San Francisco Veterans Affairs Medical Center, San Francisco, CA 94107, USA
    Semin Nucl Med 42:328-42. 2012
    ..In this review article, we present the rationale of using functional radionuclide imaging and the therapeutic implications for each of radionuclide imaging agent that have been studied in human subjects...
  26. pmc Selective activation of p53-mediated tumour suppression in high-grade tumours
    Melissa R Junttila
    University of California San Francisco, Department of Pathology and Helen Diller Family Comprehensive Cancer Center, San Francisco, California 94143 0502, USA
    Nature 468:567-71. 2010
    ..Importantly, the failure of low-level oncogenic Kras to engage p53 reveals inherent limits in the capacity of p53 to restrain early tumour evolution and in the efficacy of therapeutic p53 restoration to eradicate cancers...

Research Grants2