Srijan Sen

Summary

Affiliation: University of Michigan
Country: USA

Publications

  1. ncbi Serotonin transporter and GABAA alpha 6 receptor variants are associated with neuroticism
    Srijan Sen
    Neuroscience Program, University of Michigan, Ann Arbor, MI 48109 0720, USA
    Biol Psychiatry 55:244-9. 2004
  2. ncbi Meta-analysis of the association between a serotonin transporter promoter polymorphism (5-HTTLPR) and anxiety-related personality traits
    Srijan Sen
    Neuroscience Program, University of Michigan, Ann Arbor, Michigan 48109, USA
    Am J Med Genet B Neuropsychiatr Genet 127:85-9. 2004
  3. ncbi A prospective cohort study investigating factors associated with depression during medical internship
    Srijan Sen
    Department of Psychiatry, University of Michigan, Ann Arbor, MI 48109, USA
    Arch Gen Psychiatry 67:557-65. 2010
  4. ncbi Association between a dopamine-4 receptor polymorphism and blood pressure
    Srijan Sen
    Neuroscience Program, University of Michigan, Ann Arbor, MI 48106, USA
    Am J Hypertens 18:1206-10. 2005
  5. ncbi BDNF Val66Met allele is associated with reduced hippocampal volume in healthy subjects
    Joshua A Bueller
    Mental Health Research Institute, The University of Michigan, Ann Arbor, Michigan, USA
    Biol Psychiatry 59:812-5. 2006
  6. ncbi ADH1A variation predisposes to personality traits and substance dependence
    Lingjun Zuo
    Department of Psychiatry, Yale University School of Medicine, New Haven, CT 06516, USA
    Am J Med Genet B Neuropsychiatr Genet 153:376-86. 2010
  7. ncbi The serotonin transporter promoter variant (5-HTTLPR), stress, and depression meta-analysis revisited: evidence of genetic moderation
    Katja Karg
    Department of Human Genetics, University of Wuerzburg, Wuerzburg, Germany
    Arch Gen Psychiatry 68:444-54. 2011
  8. ncbi Major depression: emerging therapeutics
    Srijan Sen
    Department of Psychiatry, Yale University School of Medicine, New Haven, CT, USA
    Mt Sinai J Med 75:204-25. 2008
  9. ncbi A BDNF coding variant is associated with the NEO personality inventory domain neuroticism, a risk factor for depression
    Srijan Sen
    Neuroscience Program, University of Michigan, Ann Arbor, MI, USA
    Neuropsychopharmacology 28:397-401. 2003
  10. ncbi Hardy-Weinberg analysis of a large set of published association studies reveals genotyping error and a deficit of heterozygotes across multiple loci
    Srijan Sen
    Molecular and Behavioral Neuroscience Institute, University of Michigan, Ann Arbor, MI 48109, USA
    Hum Genomics 3:36-52. 2008

Research Grants

  1. Neurotransmitter Genes in Personality Trait Variation
    Srijan Sen; Fiscal Year: 2002

Detail Information

Publications11

  1. ncbi Serotonin transporter and GABAA alpha 6 receptor variants are associated with neuroticism
    Srijan Sen
    Neuroscience Program, University of Michigan, Ann Arbor, MI 48109 0720, USA
    Biol Psychiatry 55:244-9. 2004
    ..A GABA(A) receptor alpha6 subunit variant (Pro385Ser) has been associated with alcohol-related traits but has not been studied in neuroticism or depression...
  2. ncbi Meta-analysis of the association between a serotonin transporter promoter polymorphism (5-HTTLPR) and anxiety-related personality traits
    Srijan Sen
    Neuroscience Program, University of Michigan, Ann Arbor, Michigan 48109, USA
    Am J Med Genet B Neuropsychiatr Genet 127:85-9. 2004
    ....
  3. ncbi A prospective cohort study investigating factors associated with depression during medical internship
    Srijan Sen
    Department of Psychiatry, University of Michigan, Ann Arbor, MI 48109, USA
    Arch Gen Psychiatry 67:557-65. 2010
    ....
  4. ncbi Association between a dopamine-4 receptor polymorphism and blood pressure
    Srijan Sen
    Neuroscience Program, University of Michigan, Ann Arbor, MI 48106, USA
    Am J Hypertens 18:1206-10. 2005
    ..The long allele (defined as at least one 7 to 10 repeat) has been associated with the personality trait Novelty Seeking and with substance abuse, but associations between dopamine-4 receptor polymorphisms and BP have not been reported...
  5. ncbi BDNF Val66Met allele is associated with reduced hippocampal volume in healthy subjects
    Joshua A Bueller
    Mental Health Research Institute, The University of Michigan, Ann Arbor, Michigan, USA
    Biol Psychiatry 59:812-5. 2006
    ....
  6. ncbi ADH1A variation predisposes to personality traits and substance dependence
    Lingjun Zuo
    Department of Psychiatry, Yale University School of Medicine, New Haven, CT 06516, USA
    Am J Med Genet B Neuropsychiatr Genet 153:376-86. 2010
    ..008 <or= P <or= 0.060). The present study demonstrates that the ADH1A variation may contribute to the genetic component of variation in personality traits and SD...
  7. ncbi The serotonin transporter promoter variant (5-HTTLPR), stress, and depression meta-analysis revisited: evidence of genetic moderation
    Katja Karg
    Department of Human Genetics, University of Wuerzburg, Wuerzburg, Germany
    Arch Gen Psychiatry 68:444-54. 2011
    ..However, even the larger of the meta-analyses included only 14 of the 56 studies that have assessed the relationship between 5-HTTLPR, stress, and depression...
  8. ncbi Major depression: emerging therapeutics
    Srijan Sen
    Department of Psychiatry, Yale University School of Medicine, New Haven, CT, USA
    Mt Sinai J Med 75:204-25. 2008
    ..In this review, we discuss the biological basis and preclinical and clinical evidence for a series of promising classes of antidepressants developed primarily out of a pathophysiologically informed approach...
  9. ncbi A BDNF coding variant is associated with the NEO personality inventory domain neuroticism, a risk factor for depression
    Srijan Sen
    Neuroscience Program, University of Michigan, Ann Arbor, MI, USA
    Neuropsychopharmacology 28:397-401. 2003
  10. ncbi Hardy-Weinberg analysis of a large set of published association studies reveals genotyping error and a deficit of heterozygotes across multiple loci
    Srijan Sen
    Molecular and Behavioral Neuroscience Institute, University of Michigan, Ann Arbor, MI 48109, USA
    Hum Genomics 3:36-52. 2008
    ..For SNPs, HWD tends to be due to a deficit of heterozygotes, indicating that allelic dropout may be the most prevalent genotyping error...
  11. ncbi Serum brain-derived neurotrophic factor, depression, and antidepressant medications: meta-analyses and implications
    Srijan Sen
    Department of Psychiatry, Yale University School of Medicine, Connecticut Mental Health Center, New Haven, Connecticut 06519, USA
    Biol Psychiatry 64:527-32. 2008
    ..Converging lines of evidence implicate the neurotrophin brain-derived neurotrophic factor (BDNF) in the pathophysiology of major depression. Recent studies have begun to explore the relationship between serum BDNF and depression...

Research Grants1

  1. Neurotransmitter Genes in Personality Trait Variation
    Srijan Sen; Fiscal Year: 2002
    ..We will assess whether there is an association between each genotype and the relevant personality trait. Through these studies, we hope to learn more about the role of these genes in personality trait variation. ..