M Sen

Summary

Affiliation: University of California
Country: USA

Publications

  1. ncbi request reprint Regulation of fibronectin and metalloproteinase expression by Wnt signaling in rheumatoid arthritis synoviocytes
    Malini Sen
    Department of Medicine, University of California San Diego, 9500 Gilman Drive, La Jolla, CA 92093 0663, USA
    Arthritis Rheum 46:2867-77. 2002
  2. ncbi request reprint WISP3-dependent regulation of type II collagen and aggrecan production in chondrocytes
    Malini Sen
    University of California, San Diego, CA 92093 0663, USA
    Arthritis Rheum 50:488-97. 2004
  3. ncbi request reprint Wnt signalling in rheumatoid arthritis
    M Sen
    Department of Medicine, University of California San Diego, 9500 Gilman Drive, La Jolla, CA 92093 0663, USA
    Rheumatology (Oxford) 44:708-13. 2005
  4. ncbi request reprint Blockade of Wnt-5A/frizzled 5 signaling inhibits rheumatoid synoviocyte activation
    M Sen
    Department of Medicine, University of California, San Diego, La Jolla 92093-0663, USA
    Arthritis Rheum 44:772-81. 2001
  5. ncbi request reprint WISP-3 functions as a ligand and promotes superoxide dismutase activity
    Leila Davis
    Department of Chemistry and Biochemistry, University of California, San Diego, USA
    Biochem Biophys Res Commun 342:259-65. 2006
  6. ncbi request reprint Potential role of WISP3 (CCN6) in regulating the accumulation of reactive oxygen species
    Dustyn S Miller
    Department of Medicine and The Sam and Rose Stein Institute for Research on Aging SIRA, University of California San Diego UCSD, 9500 Gilman Drive, La Jolla, CA 92093 0663, USA
    Biochem Biophys Res Commun 355:156-61. 2007
  7. pmc Activation of the Wnt signaling pathway in chronic lymphocytic leukemia
    Desheng Lu
    Rebecca and John Moores UCSD Cancer Center, University of California at San Diego, La Jolla, CA 92093 0663, USA
    Proc Natl Acad Sci U S A 101:3118-23. 2004
  8. ncbi request reprint Wnt and frizzled receptors as potential targets for immunotherapy in head and neck squamous cell carcinomas
    Chae Seo Rhee
    Department of Medicine and The Sam and Rose Stein Institute for Research on Aging, University of California San Diego, La Jolla, California, CA 92093 0663, USA
    Oncogene 21:6598-605. 2002

Collaborators

Detail Information

Publications8

  1. ncbi request reprint Regulation of fibronectin and metalloproteinase expression by Wnt signaling in rheumatoid arthritis synoviocytes
    Malini Sen
    Department of Medicine, University of California San Diego, 9500 Gilman Drive, La Jolla, CA 92093 0663, USA
    Arthritis Rheum 46:2867-77. 2002
    ..The purpose of the present experiments was to determine the role of Wnt-1-like molecules in the expression of matrix proteins by RA FLS and to ascertain the effects of Wnt antagonists on RA FLS function and survival...
  2. ncbi request reprint WISP3-dependent regulation of type II collagen and aggrecan production in chondrocytes
    Malini Sen
    University of California, San Diego, CA 92093 0663, USA
    Arthritis Rheum 50:488-97. 2004
    ..WISP3 mutations have been linked to progressive pseudorheumatoid dysplasia (PPRD). The present study was conducted to investigate whether WISP3 is responsible for the expression of cartilage-specific molecules...
  3. ncbi request reprint Wnt signalling in rheumatoid arthritis
    M Sen
    Department of Medicine, University of California San Diego, 9500 Gilman Drive, La Jolla, CA 92093 0663, USA
    Rheumatology (Oxford) 44:708-13. 2005
    ..Anti-Wnt/anti-Fz antibodies, Fz receptor antagonists or small-molecule inhibitors of Wnt-Fz signalling might be useful for therapeutic interventions in refractory RA...
  4. ncbi request reprint Blockade of Wnt-5A/frizzled 5 signaling inhibits rheumatoid synoviocyte activation
    M Sen
    Department of Medicine, University of California, San Diego, La Jolla 92093-0663, USA
    Arthritis Rheum 44:772-81. 2001
    ..CONCLUSION: Wnt-5A/Fz5 signaling may contribute to the activated state of FLS in RA. Receptor antagonists of Fz5 should be considered for the treatment of refractory synovitis...
  5. ncbi request reprint WISP-3 functions as a ligand and promotes superoxide dismutase activity
    Leila Davis
    Department of Chemistry and Biochemistry, University of California, San Diego, USA
    Biochem Biophys Res Commun 342:259-65. 2006
    ..Furthermore, apart from regulating collagen II and aggrecan expression, WISP-3 may also promote superoxide dismutase expression and activity in chondrocytes...
  6. ncbi request reprint Potential role of WISP3 (CCN6) in regulating the accumulation of reactive oxygen species
    Dustyn S Miller
    Department of Medicine and The Sam and Rose Stein Institute for Research on Aging SIRA, University of California San Diego UCSD, 9500 Gilman Drive, La Jolla, CA 92093 0663, USA
    Biochem Biophys Res Commun 355:156-61. 2007
    ..Our experimental results suggest that WISP3 regulates the accumulation of cellular ROS, and mutations in WISP3 or loss of expression of WISP3 compromise this function...
  7. pmc Activation of the Wnt signaling pathway in chronic lymphocytic leukemia
    Desheng Lu
    Rebecca and John Moores UCSD Cancer Center, University of California at San Diego, La Jolla, CA 92093 0663, USA
    Proc Natl Acad Sci U S A 101:3118-23. 2004
    ..Taken together, these results indicate that Wnt signaling genes are overexpressed and are active in CLL. Uncontrolled Wnt signaling may contribute to the defect in apoptosis that characterizes this malignancy...
  8. ncbi request reprint Wnt and frizzled receptors as potential targets for immunotherapy in head and neck squamous cell carcinomas
    Chae Seo Rhee
    Department of Medicine and The Sam and Rose Stein Institute for Research on Aging, University of California San Diego, La Jolla, California, CA 92093 0663, USA
    Oncogene 21:6598-605. 2002
    ..Hence, the Wnt and Fz receptors may be possible targets for immunotherapy therapy of this common cancer...