Craig H Selzman

Summary

Affiliation: University of Colorado Health Sciences Center
Country: USA

Publications

  1. ncbi Ovarian ablation alone promotes aortic intimal hyperplasia and accumulation of fibroblast growth factor
    C H Selzman
    Departments of Surgery and Medicine, University of Colorado Health Sciences Center, Denver, CO, USA
    Circulation 98:2049-54. 1998
  2. ncbi Monocyte chemotactic protein-1 directly induces human vascular smooth muscle proliferation
    Craig H Selzman
    Divison of Cardiothoracic Surgery, University of Colorado Health Sciences Center, Denver 80262, USA
    Am J Physiol Heart Circ Physiol 283:H1455-61. 2002
  3. ncbi Inhibition of intimal hyperplasia using the selective estrogen receptor modulator raloxifene
    Craig H Selzman
    Division of Cardiothoracic Surgery, Campus Box C 310, University of Colorado Health Sciences Center, 4200 E Ninth Ave, Denver, CO 80262, USA
    Arch Surg 137:333-6. 2002
  4. ncbi Therapeutic implications of inflammation in atherosclerotic cardiovascular disease
    C H Selzman
    Department of Surgery, University of Colorado Health Sciences Center, Denver 80262, USA
    Ann Thorac Surg 71:2066-74. 2001
  5. ncbi Current approaches to therapy for vascular injury
    C H Selzman
    Division of Cardiothoracic Surgery, Box C 310, University of Colorado Health Sciences Center, 4200 East Ninth Avenue, Denver, Colorado 80262, USA
    Expert Opin Pharmacother 2:753-64. 2001
  6. ncbi The NFkappaB inhibitory peptide, IkappaBalpha, prevents human vascular smooth muscle proliferation
    C H Selzman
    Department of Surgery, University of Colorado Health Sciences Center, Denver 80262, USA
    Ann Thorac Surg 67:1227-31; discussion 1231-2. 1999
  7. ncbi Liposomal delivery of purified inhibitory-kappaBalpha inhibits tumor necrosis factor-alpha-induced human vascular smooth muscle proliferation
    C H Selzman
    Department of Surgery, University of Colorado Health Sciences Center, Denver, Colo 80262, USA
    Circ Res 84:867-75. 1999
  8. ncbi Therapeutic implications of interleukin-10 in surgical disease
    C H Selzman
    Department of Surgery, University of Colorado Health Sciences Center and The Veterans Affairs Hospital, Denver 80262, USA
    Shock 10:309-18. 1998
  9. ncbi ALCAPA in an adult with preserved left ventricular function
    Craig H Selzman
    Division of Cardiothoracic Surgery, University of Colorado Health Sciences Center, Denver, CO 80262, USA
    J Card Surg 18:25-8. 2003
  10. ncbi Proteasome inhibition promotes regression of left ventricular hypertrophy
    William E Stansfield
    Division of Cardiothoracic Surgery, Department of Surgery, University of North Carolina at Chapel Hill 27599 7065, USA
    Am J Physiol Heart Circ Physiol 294:H645-50. 2008

Collaborators

Detail Information

Publications38

  1. ncbi Ovarian ablation alone promotes aortic intimal hyperplasia and accumulation of fibroblast growth factor
    C H Selzman
    Departments of Surgery and Medicine, University of Colorado Health Sciences Center, Denver, CO, USA
    Circulation 98:2049-54. 1998
    ..We hypothesized that estrogens are atheroprotective, independent of their influence on lipid metabolism, by directly influencing the production and effects of a prototypical atherogenic mediator, basic fibroblast growth factor (bFGF)...
  2. ncbi Monocyte chemotactic protein-1 directly induces human vascular smooth muscle proliferation
    Craig H Selzman
    Divison of Cardiothoracic Surgery, University of Colorado Health Sciences Center, Denver 80262, USA
    Am J Physiol Heart Circ Physiol 283:H1455-61. 2002
    ..Within the inflammatory paradigm of vascular remodeling, these data suggest that MCP-1 is more than simply a chemokine but also a potent mitogen for VSMC proliferation...
  3. ncbi Inhibition of intimal hyperplasia using the selective estrogen receptor modulator raloxifene
    Craig H Selzman
    Division of Cardiothoracic Surgery, Campus Box C 310, University of Colorado Health Sciences Center, 4200 E Ninth Ave, Denver, CO 80262, USA
    Arch Surg 137:333-6. 2002
    ..The selective estrogen receptor modulator raloxifene hydrochloride inhibits intimal hyperplasia...
  4. ncbi Therapeutic implications of inflammation in atherosclerotic cardiovascular disease
    C H Selzman
    Department of Surgery, University of Colorado Health Sciences Center, Denver 80262, USA
    Ann Thorac Surg 71:2066-74. 2001
    ..By examining mechanisms involved in the response to vascular injury, we can more effectively implement targeted therapy aimed at halting or regressing arteriosclerosis...
  5. ncbi Current approaches to therapy for vascular injury
    C H Selzman
    Division of Cardiothoracic Surgery, Box C 310, University of Colorado Health Sciences Center, 4200 East Ninth Avenue, Denver, Colorado 80262, USA
    Expert Opin Pharmacother 2:753-64. 2001
    ..In addition, future therapeutic strategies, based within this inflammatory paradigm, are discussed...
  6. ncbi The NFkappaB inhibitory peptide, IkappaBalpha, prevents human vascular smooth muscle proliferation
    C H Selzman
    Department of Surgery, University of Colorado Health Sciences Center, Denver 80262, USA
    Ann Thorac Surg 67:1227-31; discussion 1231-2. 1999
    ..We hypothesized that strategies aimed at inhibiting NFkappaB would abrogate mitogen-induced human VSMC proliferation...
  7. ncbi Liposomal delivery of purified inhibitory-kappaBalpha inhibits tumor necrosis factor-alpha-induced human vascular smooth muscle proliferation
    C H Selzman
    Department of Surgery, University of Colorado Health Sciences Center, Denver, Colo 80262, USA
    Circ Res 84:867-75. 1999
    ..Furthermore, liposomal delivery of endogenous inhibitory proteins may represent a novel, therapeutically accessible method for selective transcriptional suppression in the response to vascular injury...
  8. ncbi Therapeutic implications of interleukin-10 in surgical disease
    C H Selzman
    Department of Surgery, University of Colorado Health Sciences Center and The Veterans Affairs Hospital, Denver 80262, USA
    Shock 10:309-18. 1998
    ..In conclusion, IL-10 is an important mediator of immune and anti-inflammatory responses in surgical disease and, as such, has therapeutic promise as an immunomodulator and as an anti-inflammatory agent...
  9. ncbi ALCAPA in an adult with preserved left ventricular function
    Craig H Selzman
    Division of Cardiothoracic Surgery, University of Colorado Health Sciences Center, Denver, CO 80262, USA
    J Card Surg 18:25-8. 2003
    ..We report a case of ALCAPA in a 23-year-old female with completely preserved left ventricular function. This article reviews the mechanism of this unusual presentation as well as the therapeutic options for adults presenting with ALCAPA...
  10. ncbi Proteasome inhibition promotes regression of left ventricular hypertrophy
    William E Stansfield
    Division of Cardiothoracic Surgery, Department of Surgery, University of North Carolina at Chapel Hill 27599 7065, USA
    Am J Physiol Heart Circ Physiol 294:H645-50. 2008
    ....
  11. doi Inhibitory kappa B kinase-beta is a target for specific nuclear factor kappa B-mediated delayed cardioprotection
    Nancy C Moss
    Department of Surgery, University of North Carolina, Chapel Hill, North Carolina 27599, USA
    J Thorac Cardiovasc Surg 136:1274-9. 2008
    ..We targeted 2 proteins in the nuclear factor-kappaB pathway, inhibitory kappa B kinase-beta, and 26S cardiac proteasome to determine their cardioprotective effects when delivered during reperfusion...
  12. pmc Periostin is a novel factor in cardiac remodeling after experimental and clinical unloading of the failing heart
    William E Stansfield
    Division of Cardiothoracic Surgery, Department of Surgery, University of North Carolina, Chapel Hill, North Carolina, USA
    Ann Thorac Surg 88:1916-21. 2009
    ..Because of its potential role in cardiovascular development, we sought to establish the role of periostin after relief of pressure overload in animal and human models...
  13. ncbi Interleukin-10 attenuates the response to vascular injury
    Michael A Zimmerman
    Department of Surgery, University of Colorado Health, Sciences Center, Denver, Colorado, USA
    J Surg Res 121:206-13. 2004
    ..Few studies have evaluated the effects of IL-10 in experimental atherosclerosis. The purpose of the present study was to determine the influence of IL-10 on vascular inflammation and IH following mechanical injury...
  14. ncbi IKKbeta inhibition attenuates myocardial injury and dysfunction following acute ischemia-reperfusion injury
    Nancy C Moss
    Department of Surgery, University of North Carolina, Chapel Hill, North Carolina 27599 7065, USA
    Am J Physiol Heart Circ Physiol 293:H2248-53. 2007
    ..These results demonstrate that specific IKKbeta inhibition can provide both acute and delayed cardioprotection and offers a clinically accessible target for preventing cardiac injury following IR...
  15. ncbi Lack of TNF-alpha attenuates intimal hyperplasia after mouse carotid artery injury
    Michael A Zimmerman
    Department of Surgery, University of Colorado Health Sciences Center, Denver 80262, USA
    Am J Physiol Regul Integr Comp Physiol 283:R505-12. 2002
    ..Finally, TNF(-/-) animals demonstrated a sevenfold reduction in IH compared with WT animals. Cumulatively, these data mechanistically link TNF-alpha and NF-kappaB in vivo and suggest an important influence of TNF-alpha on postinjury IH...
  16. pmc Recovery from decompensated heart failure is associated with a distinct, phase-dependent gene expression profile
    Nancy M Andersen
    Department of Surgery, University of North Carolina, Chapel Hill, North Carolina, USA
    J Surg Res 178:72-80. 2012
    ..We hypothesize that the pathways involved with myocardial recovery are not simply the reverse of those that cause heart failure. However, determining when and how a decompensated heart can recover remains unknown...
  17. ncbi Relative contribution of the TNF-alpha receptors to murine intimal hyperplasia
    Michael A Zimmerman
    Divisions of Cardiothoracic Surgery and Infectious Disease, University of Colorado Health Sciences Center, Denver, Colorado 80262, USA
    Am J Physiol Regul Integr Comp Physiol 284:R1213-8. 2003
    ..Suppression of the transcriptional activator nuclear factor-kappaB may provide a mechanism by which p55-mediated IH is attenuated...
  18. pmc Cardiomyocyte-specific p65 NF-κB deletion protects the injured heart by preservation of calcium handling
    Xiu Q Zhang
    Division of Cardiothoracic Surgery, Department of Surgery, University of Utah, Salt Lake City, Utah
    Am J Physiol Heart Circ Physiol 305:H1089-97. 2013
    ..The beneficial effects of NF-κB inhibition are related, in part, to modulation of intracellular calcium homeostasis. ..
  19. ncbi Interleukin-11 attenuates human vascular smooth muscle cell proliferation
    Michael A Zimmerman
    Division of Cardiothoracic Surgery, University of Colorado Health Sciences Center, Denver, Colorado 80262, USA
    Am J Physiol Heart Circ Physiol 283:H175-80. 2002
    ..Stimulated VSMC did not secrete IL-11, suggesting that endogenous IL-11 did not account for our observations. In conclusion, IL-11 inhibits human VSMC proliferation in vitro and is associated with suppression of NF-kappa B...
  20. pmc Regression of pressure-induced left ventricular hypertrophy is characterized by a distinct gene expression profile
    William E Stansfield
    Department of Surgery, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA
    J Thorac Cardiovasc Surg 137:232-8, 238e1-8. 2009
    ..We propose an alternative strategy focusing on mechanisms of left ventricular hypertrophy regression rather than its progression and hypothesize that left ventricular hypertrophy regression is associated with a distinct genomic profile...
  21. ncbi Impact of ventricular assist device complications on posttransplant survival: an analysis of the United network of organ sharing database
    Aaron H Healy
    Department of Surgery, University of Utah School of Medicine, Salt Lake City, UT 84132, USA
    Ann Thorac Surg 95:870-5. 2013
    ..We sought to determine if the presence or absence of complications in status 1A LVAD patients at the time of transplant influenced survival after transplant...
  22. doi Improved survival in heart transplant patients living at high altitude
    Curtis J Wozniak
    Division of Cardiothoracic Surgery, University of Utah, Salt Lake City, UT 84132 2101, USA
    J Thorac Cardiovasc Surg 143:735-741.e1. 2012
    ..The purpose of the present study was to determine whether altitude negatively affects survival among patients undergoing heart transplantation...
  23. ncbi Diagnostic implications of C-reactive protein
    Michael A Zimmerman
    Department of Surgery, Campus Box C 320, University of Colorado Health Sciences Center, 4200 East Ninth Ave, Denver, Colo 80262, USA
    Arch Surg 138:220-4. 2003
    ..Determining whether CRP has a direct pathologic role in the vascular wall itself may have the most clinical relevance...
  24. pmc Inhibitory kappa-B kinase-β inhibition prevents adaptive left ventricular hypertrophy
    Nancy M Andersen
    Department of Surgery, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, USA
    J Surg Res 178:105-9. 2012
    ..In contrast to its known effects related to myocardial ischemia-reperfusion, we hypothesized that NF-κB is necessary for the compensatory phase of cardiac remodeling...
  25. ncbi Proteasome inhibition attenuates infarct size and preserves cardiac function in a murine model of myocardial ischemia-reperfusion injury
    William E Stansfield
    Department of Surgery, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina 27599 7065, USA
    Ann Thorac Surg 84:120-5. 2007
    ..Its activation relies on the degradation of its inhibitory molecule, IkappaB, by the 20S proteasome. We hypothesized that proteasome inhibition would decrease the extent of infarction after temporary coronary occlusion...
  26. ncbi Characterization of a model to independently study regression of ventricular hypertrophy
    William E Stansfield
    Department of Surgery, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, USA
    J Surg Res 142:387-93. 2007
    ..While traditional models of aortic banding have provided useful information regarding the development of LVH, a similarly effective model is necessary to study mechanisms associated with LVH regression...
  27. ncbi Off-pump insertion of continuous flow left ventricular assist devices
    Craig H Selzman
    Division of Cardiothoracic Surgery, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina 27599 7065, USA
    J Card Surg 22:320-2. 2007
    ..Potential adverse effects of CPB in very ill end-stage heart failure patients include right ventricular dysfunction, end-organ injury, and bleeding. We sought to evaluate the feasibility and outcome of LVAD insertion without CPB...
  28. ncbi Vasopressin in the cardiac surgery intensive care unit
    Tracy N Albright
    Cardiothoracic Surgery Service, Veterans Administration Medical Center, Denver, Colo, USA
    Am J Crit Care 11:326-30; quiz 331-2. 2002
    ....
  29. ncbi Atherogenic effects of Chlamydia pneumoniae: refuting the innocent bystander hypothesis
    Craig H Selzman
    Division of Cardiothoracic Surgery, University of North Carolina School of Medicine, Wing C, CB 7065, Chapel Hill, NC 27599, USA
    J Thorac Cardiovasc Surg 126:688-93. 2003
    ..pneumoniae infection of human vascular smooth muscle cells on vascular smooth muscle cell proliferation, cell-cycle protein expression, and inflammatory cytokine release...
  30. doi The impact of bridge-to-transplant ventricular assist device support on survival after cardiac transplantation
    David A Bull
    Division of Cardiothoracic Surgery, Department of Surgery, University of Utah Health Sciences Center, Salt Lake City, Utah 84132, USA
    J Thorac Cardiovasc Surg 140:169-73. 2010
    ..To determine the impact of bridge-to-transplant ventricular assist device support on survival after cardiac transplantation...
  31. doi Experience with the Levitronix CentriMag in the pediatric population as a bridge to decision and recovery
    Peter C Kouretas
    Department of Surgery, The University of Utah, Primary Children s Medical Center, Salt Lake City, UT, USA
    Artif Organs 33:1002-4. 2009
    ..The Levitronix CentriMag has proven to be a versatile, safe, and effective short-term circulatory support system for our pediatric patients...
  32. ncbi Pharmacologic therapies for acute cardiogenic shock
    Jose Nativi-Nicolau
    aDivision of Cardiovascular Medicine, Department of Medicine, University of Utah School of Medicine bCardiology Section, Veterans Affairs Salt Lake City Healthcare System cDivision of Cardiothoracic Surgery, Department of Surgery, University of Utah School of Medicine, Salt Lake City, Utah, USA
    Curr Opin Cardiol 29:250-7. 2014
    ..In this article, we review the current pharmacological agents utilized during cardiogenic shock...
  33. ncbi Use of the Jarvik 2000 continuous flow left ventricular assist device for acute myocardial infarction and cardiogenic shock
    Craig H Selzman
    Division of Cardiothoracic Surgery, University of North Carolina, Chapel Hill, North Carolina 27599 7065, USA
    J Heart Lung Transplant 26:756-8. 2007
    ..We report the novel use of a continuous flow left ventricular assist device (LVAD) for successful recovery and bridging to transplantation in a patient who had massive anterior wall myocardial infarction...
  34. doi Invited commentary
    Craig H Selzman
    Division of Cardiothoracic Surgery, University of North Carolina, CB 7065, 3040 Burnett Womack Building, Chapel Hill, NC 27599 7065, USA
    Ann Thorac Surg 85:585-6. 2008
  35. ncbi Vasopressin in cardiovascular patients: therapeutic implications
    Michael A Zimmerman
    Division of Cardiothoracic Surgery, Box C 310, University of Colorado Health Sciences Center, 4200 East Ninth Avenue, Denver, Colorado 80262, USA
    Expert Opin Pharmacother 3:505-12. 2002
    ..This manuscript reviews the pathophysiological and clinical basis for vasopressin replacement in patients with cardiovascular collapse...
  36. ncbi NFkappaB decoys to prevent vein graft stenosis Invited Editorial on "inhibitory effects of NFkappaB decoy oligodeoxynucleotides on neointimal hyperplasia in a rabbit vein graft model"
    Craig H Selzman
    J Mol Cell Cardiol 41:410-2. 2006
  37. ncbi Case 115: aortic pseudoaneurysm from penetrating superior vena cava stent
    David M Warshauer
    Department of Radiology, University of North Carolina School of Medicine, Campus Box 7510, Chapel Hill, NC 27599 7510, USA
    Radiology 243:901-4. 2007
  38. pmc Myocardin inhibits cellular proliferation by inhibiting NF-kappaB(p65)-dependent cell cycle progression
    Ru Hang Tang
    Departments of Surgery and Cell and Developmental Biology, Carolina Cardiovascular Biology Center, and Lineberger Comprehensive Cancer Center, University of North Carolina, Chapel Hill, NC 27599, USA
    Proc Natl Acad Sci U S A 105:3362-7. 2008
    ....