G B Segel

Summary

Affiliation: University of Rochester
Country: USA

Publications

  1. ncbi Anticoagulant proteins in childhood venous and arterial thrombosis: a review
    G B Segel
    Division of Pediatric Hematology Oncology, Box 777, University of Rochester Medical Center, Children s Hospital at Strong, 601 Elmwood Avenue, Rochester, New York 14642, USA
    Blood Cells Mol Dis 26:540-60. 2000
  2. ncbi Early gene activation in chronic leukemic B lymphocytes induced toward a plasma cell phenotype
    George B Segel
    Department of Pediatrics, and Unity Health System, University of Rochester School of Medicine and Dentistry, Rochester, NY 14642, USA
    Blood Cells Mol Dis 30:277-87. 2003
  3. ncbi Controversies in the diagnosis and management of childhood acute immune thrombocytopenic purpura
    George B Segel
    Department of Pediatrics, Golisano Children s Hospital, University of Rochester School of Medicine, Rochester, New York 14642, USA
    Pediatr Blood Cancer 53:318-24. 2009
  4. ncbi The paradox of the neutrophil's role in tissue injury
    George B Segel
    Department of Pediatrics, University of Rochester Medical Center, Rochester, New York, USA
    J Leukoc Biol 89:359-72. 2011
  5. ncbi Cloning of rabbit Cct6 and the distribution of the Cct complex in mammalian tissues
    G J Schwartz
    Department of Pediatrics, University of Rochester School of Medicine, Rochester, NY 14642, USA
    Exp Nephrol 8:152-60. 2000
  6. ncbi Uncommon phenotypes of acute myelogenous leukemia: basophilic, mast cell, eosinophilic, and myeloid dendritic cell subtypes: a review
    Marshall A Lichtman
    University of Rochester Medical Center, Rochester, NY 14642, USA
    Blood Cells Mol Dis 35:370-83. 2005
  7. ncbi The Na+/H+ exchanger in immature and mature granulocytic HL-60 cells. Property changes induced by intracellular acidification and cell maturation
    M R Costa-Casnellie
    Department of Medicine, University of Rochester Medical Center, New York 14642
    J Biol Chem 263:11851-5. 1988
  8. ncbi Photoinhibition of 2-amino-2-carboxybicyclo[2,2,1]heptane transport by O-diazoacetyl-L-serine. An initial step in identifying the L-system amino acid transporter
    G B Segel
    Department of Pediatrics, University of Rochester School of Medicine, New York 14642
    J Biol Chem 264:16399-402. 1989
  9. ncbi Prohibitin expression is increased in phorbol ester-treated chronic leukemic B-lymphocytes
    T J Woodlock
    Department of Medicine, University of Rochester School of Medicine and Dentistry, Rochester, New York 14642, USA
    Blood Cells Mol Dis 27:27-34. 2001

Collaborators

Detail Information

Publications9

  1. ncbi Anticoagulant proteins in childhood venous and arterial thrombosis: a review
    G B Segel
    Division of Pediatric Hematology Oncology, Box 777, University of Rochester Medical Center, Children s Hospital at Strong, 601 Elmwood Avenue, Rochester, New York 14642, USA
    Blood Cells Mol Dis 26:540-60. 2000
    ....
  2. ncbi Early gene activation in chronic leukemic B lymphocytes induced toward a plasma cell phenotype
    George B Segel
    Department of Pediatrics, and Unity Health System, University of Rochester School of Medicine and Dentistry, Rochester, NY 14642, USA
    Blood Cells Mol Dis 30:277-87. 2003
    ..These findings suggest that the products of these three genes may be central to early steps in the TPA-induced evolution of CLL B cells to a plasmacytic phenotype...
  3. ncbi Controversies in the diagnosis and management of childhood acute immune thrombocytopenic purpura
    George B Segel
    Department of Pediatrics, Golisano Children s Hospital, University of Rochester School of Medicine, Rochester, New York 14642, USA
    Pediatr Blood Cancer 53:318-24. 2009
    ..Therefore, careful observation may be the best management option for the patient with ITP, in the absence of severe bleeding. The data available relevant to these issues are discussed...
  4. ncbi The paradox of the neutrophil's role in tissue injury
    George B Segel
    Department of Pediatrics, University of Rochester Medical Center, Rochester, New York, USA
    J Leukoc Biol 89:359-72. 2011
    ..In this review, we summarize the evidence for its role as a mediator of tissue injury in these seven conditions, making it or its products potential therapeutic targets...
  5. ncbi Cloning of rabbit Cct6 and the distribution of the Cct complex in mammalian tissues
    G J Schwartz
    Department of Pediatrics, University of Rochester School of Medicine, Rochester, NY 14642, USA
    Exp Nephrol 8:152-60. 2000
    ..These data characterize the rabbit Cct6 subunit and compare it to its homologues. The Western analyses support the concept that Cct complex is widely distributed among tissues and highly conserved among eukaryotes...
  6. ncbi Uncommon phenotypes of acute myelogenous leukemia: basophilic, mast cell, eosinophilic, and myeloid dendritic cell subtypes: a review
    Marshall A Lichtman
    University of Rochester Medical Center, Rochester, NY 14642, USA
    Blood Cells Mol Dis 35:370-83. 2005
    ..We discuss the features of these uncommon phenotypes and review the criteria used for their diagnosis...
  7. ncbi The Na+/H+ exchanger in immature and mature granulocytic HL-60 cells. Property changes induced by intracellular acidification and cell maturation
    M R Costa-Casnellie
    Department of Medicine, University of Rochester Medical Center, New York 14642
    J Biol Chem 263:11851-5. 1988
    ..At lower intracellular pH, 5.9, the inhibition was mixed in both types of cells. Thus, the properties of the exchanger in granulocytic cells are influenced by the cell maturation stage and the intracellular pH...
  8. ncbi Photoinhibition of 2-amino-2-carboxybicyclo[2,2,1]heptane transport by O-diazoacetyl-L-serine. An initial step in identifying the L-system amino acid transporter
    G B Segel
    Department of Pediatrics, University of Rochester School of Medicine, New York 14642
    J Biol Chem 264:16399-402. 1989
    ..Thus, photolysis of azaserine provides an initial step toward the identification of the L-system transporter...
  9. ncbi Prohibitin expression is increased in phorbol ester-treated chronic leukemic B-lymphocytes
    T J Woodlock
    Department of Medicine, University of Rochester School of Medicine and Dentistry, Rochester, New York 14642, USA
    Blood Cells Mol Dis 27:27-34. 2001
    ..These data suggest that increased prohibitin expression is associated with and may facilitate B-cell maturation...