Eric R Secor

Summary

Affiliation: University of Connecticut Health Center
Country: USA

Publications

  1. ncbi request reprint Bromelain limits airway inflammation in an ovalbumin-induced murine model of established asthma
    Eric R Secor
    Department of Immunology, University of Connecticut School of Medicine, CT, USA
    Altern Ther Health Med 18:9-17. 2012
  2. pmc Bromelain treatment reduces CD25 expression on activated CD4+ T cells in vitro
    Eric R Secor
    Department of Immunology, University of Connecticut Health Center 263 Farmington Ave, MC1319Farmington, CT 06030, USA
    Int Immunopharmacol 9:340-6. 2009
  3. pmc Subcutaneous late phase responses are augmented during local inhalational tolerance in a murine asthma model
    Anurag Singh
    1Department of Immunology, University of Connecticut Health Center, Farmington, CT, USA
    Immunol Cell Biol 86:535-8. 2008
  4. pmc Phenotypic changes to the endogenous antigen-specific CD8+ T cell response correlates with the development and resolution of allergic airway disease
    Jeffrey T McNamara
    Department of Immunology, University of Connecticut Health Center, Farmington, Connecticut 06030, USA
    Am J Pathol 180:1991-2000. 2012
  5. pmc Regulatory role of B cells in a murine model of allergic airway disease
    Anurag Singh
    Department of Immunology, University of Connecticut Health Center, Framington, CT 06030, USA
    J Immunol 180:7318-26. 2008
  6. pmc Bromelain exerts anti-inflammatory effects in an ovalbumin-induced murine model of allergic airway disease
    Eric R Secor
    Department of Immunology, University of Connecticut, School of Medicine, Farmington, CT, USA
    Cell Immunol 237:68-75. 2005
  7. ncbi request reprint Interleukin-10 does not mediate inhalational tolerance in a chronic model of ovalbumin-induced allergic airway disease
    Prakash M Kabbur
    Department of Pediatrics, University of Connecticut School of Medicine, Farmington, USA
    Cell Immunol 239:67-74. 2006
  8. pmc Oral Bromelain Attenuates Inflammation in an Ovalbumin-induced Murine Model of Asthma
    Eric R Secor
    Department of Immunology and Department of Pediatrics, University of Connecticut School of Medicine, Farmington, CT, USA
    Evid Based Complement Alternat Med 5:61-9. 2008
  9. ncbi request reprint Implementation of outcome measures in a complementary and alternative medicine clinic: evidence of decreased pain and improved quality of life
    Eric R Secor
    Wellness Center, New Britain, CT, USA
    J Altern Complement Med 10:506-13. 2004
  10. pmc LC-MS/MS Identification of a Bromelain Peptide Biomarker from Ananas comosus Merr
    Eric R Secor
    Department of Immunology, UCONN Health Center, Farmington, CT 06030 1319, USA
    Evid Based Complement Alternat Med 2012:548486. 2012

Collaborators

Detail Information

Publications10

  1. ncbi request reprint Bromelain limits airway inflammation in an ovalbumin-induced murine model of established asthma
    Eric R Secor
    Department of Immunology, University of Connecticut School of Medicine, CT, USA
    Altern Ther Health Med 18:9-17. 2012
    ..Researchers are investigating the benefits of lifestyle changes and alternative asthma treatments, including the ability of bromelain to inhibit inflammation. Bromelain is a commonly used, proteolytically active pineapple extract...
  2. pmc Bromelain treatment reduces CD25 expression on activated CD4+ T cells in vitro
    Eric R Secor
    Department of Immunology, University of Connecticut Health Center 263 Farmington Ave, MC1319Farmington, CT 06030, USA
    Int Immunopharmacol 9:340-6. 2009
    ..This novel mechanism of action identifies how Br may exert its therapeutic benefits in inflammatory conditions...
  3. pmc Subcutaneous late phase responses are augmented during local inhalational tolerance in a murine asthma model
    Anurag Singh
    1Department of Immunology, University of Connecticut Health Center, Farmington, CT, USA
    Immunol Cell Biol 86:535-8. 2008
    ..Thus, the resolution of airway inflammatory responses with chronic antigen inhalation is a localized response, not associated with loss of systemic responses to antigen...
  4. pmc Phenotypic changes to the endogenous antigen-specific CD8+ T cell response correlates with the development and resolution of allergic airway disease
    Jeffrey T McNamara
    Department of Immunology, University of Connecticut Health Center, Farmington, Connecticut 06030, USA
    Am J Pathol 180:1991-2000. 2012
    ..These B cell aggregates resembled tertiary ectopic lymphoid tissue and may thus provide a local environment for the salient cellular interactions that contribute to the development of LIT...
  5. pmc Regulatory role of B cells in a murine model of allergic airway disease
    Anurag Singh
    Department of Immunology, University of Connecticut Health Center, Framington, CT 06030, USA
    J Immunol 180:7318-26. 2008
    ..These findings illustrated a novel regulatory role for regional B cells in AAD and suggested a possible contributory role of B cells, along with other cell types, in the establishment of LIT...
  6. pmc Bromelain exerts anti-inflammatory effects in an ovalbumin-induced murine model of allergic airway disease
    Eric R Secor
    Department of Immunology, University of Connecticut, School of Medicine, Farmington, CT, USA
    Cell Immunol 237:68-75. 2005
    ..The purpose of this study was to determine the effect of bromelain treatment in an ovalbumin (OVA)-induced murine model of allergic airway disease (AAD)...
  7. ncbi request reprint Interleukin-10 does not mediate inhalational tolerance in a chronic model of ovalbumin-induced allergic airway disease
    Prakash M Kabbur
    Department of Pediatrics, University of Connecticut School of Medicine, Farmington, USA
    Cell Immunol 239:67-74. 2006
    ..This study determined whether IL-10-dependent mechanisms mediated the local inhalational tolerance seen with chronic inhalational exposure to antigen...
  8. pmc Oral Bromelain Attenuates Inflammation in an Ovalbumin-induced Murine Model of Asthma
    Eric R Secor
    Department of Immunology and Department of Pediatrics, University of Connecticut School of Medicine, Farmington, CT, USA
    Evid Based Complement Alternat Med 5:61-9. 2008
    ..0001) in AAD mice when compared with controls. These results suggest that oral treatment with bromelain had a beneficial therapeutic effect in this murine model of asthma and bromelain may also be effective in human conditions...
  9. ncbi request reprint Implementation of outcome measures in a complementary and alternative medicine clinic: evidence of decreased pain and improved quality of life
    Eric R Secor
    Wellness Center, New Britain, CT, USA
    J Altern Complement Med 10:506-13. 2004
    ....
  10. pmc LC-MS/MS Identification of a Bromelain Peptide Biomarker from Ananas comosus Merr
    Eric R Secor
    Department of Immunology, UCONN Health Center, Farmington, CT 06030 1319, USA
    Evid Based Complement Alternat Med 2012:548486. 2012
    ..In this study, a novel Br peptide was identified in the plasma of treated mice for the first time. This Br peptide could serve as a biomarker to standardize the therapeutic dose and maximize clinical utility...