Affiliation: University of California
- The power of the Transmission Disequilibrium Test in the presence of population stratificationRonnie Sebro
Institute for Human Genetics, University of California, San Francisco, San Francisco, CA 94143 0794, USA
Eur J Hum Genet 18:1032-8. 2010..This method potentially aids in reducing the number of false-negative association studies...
- Testing for non-random mating: evidence for ancestry-related assortative mating in the Framingham heart studyRonnie Sebro
Institute for Human Genetics, University of California San Francisco, San Francisco, California 94143 0794, USA
Genet Epidemiol 34:674-9. 2010..This nonrandom mating likely affects genetic structure seen more generally in the North American population of European descent today, and decreases the rate of decay of linkage disequilibrium for ancestrally informative markers...
- Differentiating population stratification from genotyping error using family dataRonnie Sebro
Institute for Human Genetics, University of California, San Francisco, 513 Parnassus Avenue, Suite S965, San Francisco, CA 94143, USA
Ann Hum Genet 76:42-52. 2012..We simulate data based on several models of genotyping error in previously published literature, and show how this method could be used in practice to assist in differentiating population stratification from systematic genotyping error...
- Ancestry-related assortative mating in Latino populationsNeil Risch
Institute for Human Genetics, University of California, San Francisco, 513 Parnassus Ave, San Francisco, CA 94143, USA
Genome Biol 10:R132. 2009..While spouse correlations have been documented for numerous traits, no prior studies have assessed assortative mating for genetic ancestry in admixed populations...
- Functional genomics of membrane transporters in human populationsThomas J Urban
Department of Biopharmaceutical Sciences, San Francisco, CA 94143, USA
Genome Res 16:223-30. 2006..These variants and the reduced function variants provide plausible candidates for disease susceptibility or variation in clinical drug response...