Patrick Seale

Summary

Affiliation: University of Pennsylvania
Country: USA

Publications

  1. pmc Prdm16 determines the thermogenic program of subcutaneous white adipose tissue in mice
    Patrick Seale
    Institute for Diabetes, Obesity, and Metabolism and Department of Cell and Developmental Biology, University of Pennsylvania School of Medicine, Philadelphia, Pennsylvania, USA
    J Clin Invest 121:96-105. 2011
  2. ncbi request reprint Orexin turns up the heat on obesity
    Patrick Seale
    Institute for Diabetes, Obesity, and Metabolism, University of Pennsylvania, PA 19104, USA
    Cell Metab 14:441-2. 2011
  3. pmc Medicine. Beige can be slimming
    Jeff Ishibashi
    Institute for Diabetes, Obesity and Metabolism and the Department of Cell and Developmental Biology, University of Pennsylvania School of Medicine, Philadelphia, PA 19104, USA
    Science 328:1113-4. 2010
  4. pmc EBF2 Determines and Maintains Brown Adipocyte Identity
    Sona Rajakumari
    Institute for Diabetes, Obesity, and Metabolism, Perelman School of Medicine at the University of Pennsylvania, Philadelphia, PA 19104, USA Department of Cell and Developmental Biology, Perelman School of Medicine at the University of Pennsylvania, Philadelphia, PA 19104, USA
    Cell Metab 17:562-74. 2013
  5. pmc An Evi1-C/EBPβ complex controls peroxisome proliferator-activated receptor γ2 gene expression to initiate white fat cell differentiation
    Jeff Ishibashi
    Institute for Diabetes, Obesity and Metabolism, Department of Cell and Developmental Biology, Perelman School of Medicine at the University of Pennsylvania, Philadelphia, Pennsylvania, USA
    Mol Cell Biol 32:2289-99. 2012

Collaborators

  • Jun Wu
  • Jeff Ishibashi
  • Sona Rajakumari
  • Hee Woong Lim
  • An Hoa Giang
  • Kyoung Jae Won
  • Randall R Reed
  • Kathleen H Wood
  • Heather M Conroe
  • Zeynep Firtina
  • David J Steger

Detail Information

Publications5

  1. pmc Prdm16 determines the thermogenic program of subcutaneous white adipose tissue in mice
    Patrick Seale
    Institute for Diabetes, Obesity, and Metabolism and Department of Cell and Developmental Biology, University of Pennsylvania School of Medicine, Philadelphia, Pennsylvania, USA
    J Clin Invest 121:96-105. 2011
    ..These results demonstrate that Prdm16 is a cell-autonomous determinant of a brown fat-like gene program and thermogenesis in subcutaneous adipose tissues...
  2. ncbi request reprint Orexin turns up the heat on obesity
    Patrick Seale
    Institute for Diabetes, Obesity, and Metabolism, University of Pennsylvania, PA 19104, USA
    Cell Metab 14:441-2. 2011
    ..Sellayah et al. now reveal that a secreted neuropeptide, Orexin, functions a key driver of brown adipocyte differentiation through direct actions on brown adipose precursors...
  3. pmc Medicine. Beige can be slimming
    Jeff Ishibashi
    Institute for Diabetes, Obesity and Metabolism and the Department of Cell and Developmental Biology, University of Pennsylvania School of Medicine, Philadelphia, PA 19104, USA
    Science 328:1113-4. 2010
  4. pmc EBF2 Determines and Maintains Brown Adipocyte Identity
    Sona Rajakumari
    Institute for Diabetes, Obesity, and Metabolism, Perelman School of Medicine at the University of Pennsylvania, Philadelphia, PA 19104, USA Department of Cell and Developmental Biology, Perelman School of Medicine at the University of Pennsylvania, Philadelphia, PA 19104, USA
    Cell Metab 17:562-74. 2013
    ..Together, these results identify Ebf2 as a key transcriptional regulator of brown fat cell fate and function...
  5. pmc An Evi1-C/EBPβ complex controls peroxisome proliferator-activated receptor γ2 gene expression to initiate white fat cell differentiation
    Jeff Ishibashi
    Institute for Diabetes, Obesity and Metabolism, Department of Cell and Developmental Biology, Perelman School of Medicine at the University of Pennsylvania, Philadelphia, Pennsylvania, USA
    Mol Cell Biol 32:2289-99. 2012
    ..These results indicate that Evi1 is a key regulator of adipogenic competency...