Patrick Seale

Summary

Affiliation: University of Pennsylvania
Country: USA

Publications

  1. ncbi Prdm16 determines the thermogenic program of subcutaneous white adipose tissue in mice
    Patrick Seale
    Institute for Diabetes, Obesity, and Metabolism and Department of Cell and Developmental Biology, University of Pennsylvania School of Medicine, Philadelphia, Pennsylvania, USA
    J Clin Invest 121:96-105. 2011
  2. ncbi Orexin turns up the heat on obesity
    Patrick Seale
    Institute for Diabetes, Obesity, and Metabolism, University of Pennsylvania, PA 19104, USA
    Cell Metab 14:441-2. 2011
  3. ncbi Medicine. Beige can be slimming
    Jeff Ishibashi
    Institute for Diabetes, Obesity and Metabolism and the Department of Cell and Developmental Biology, University of Pennsylvania School of Medicine, Philadelphia, PA 19104, USA
    Science 328:1113-4. 2010
  4. ncbi An Evi1-C/EBPβ complex controls peroxisome proliferator-activated receptor γ2 gene expression to initiate white fat cell differentiation
    Jeff Ishibashi
    Institute for Diabetes, Obesity and Metabolism, Department of Cell and Developmental Biology, Perelman School of Medicine at the University of Pennsylvania, Philadelphia, Pennsylvania, USA
    Mol Cell Biol 32:2289-99. 2012

Collaborators

  • Jeff Ishibashi
  • Heather M Conroe
  • Zeynep Firtina
  • Kathleen H Wood
  • Sona Rajakumari
  • David J Steger

Detail Information

Publications4

  1. ncbi Prdm16 determines the thermogenic program of subcutaneous white adipose tissue in mice
    Patrick Seale
    Institute for Diabetes, Obesity, and Metabolism and Department of Cell and Developmental Biology, University of Pennsylvania School of Medicine, Philadelphia, Pennsylvania, USA
    J Clin Invest 121:96-105. 2011
    ..These results demonstrate that Prdm16 is a cell-autonomous determinant of a brown fat-like gene program and thermogenesis in subcutaneous adipose tissues...
  2. ncbi Orexin turns up the heat on obesity
    Patrick Seale
    Institute for Diabetes, Obesity, and Metabolism, University of Pennsylvania, PA 19104, USA
    Cell Metab 14:441-2. 2011
    ..Sellayah et al. now reveal that a secreted neuropeptide, Orexin, functions a key driver of brown adipocyte differentiation through direct actions on brown adipose precursors...
  3. ncbi Medicine. Beige can be slimming
    Jeff Ishibashi
    Institute for Diabetes, Obesity and Metabolism and the Department of Cell and Developmental Biology, University of Pennsylvania School of Medicine, Philadelphia, PA 19104, USA
    Science 328:1113-4. 2010
  4. ncbi An Evi1-C/EBPβ complex controls peroxisome proliferator-activated receptor γ2 gene expression to initiate white fat cell differentiation
    Jeff Ishibashi
    Institute for Diabetes, Obesity and Metabolism, Department of Cell and Developmental Biology, Perelman School of Medicine at the University of Pennsylvania, Philadelphia, Pennsylvania, USA
    Mol Cell Biol 32:2289-99. 2012
    ..These results indicate that Evi1 is a key regulator of adipogenic competency...