Mark E Scott

Summary

Affiliation: University of California
Country: USA

Publications

  1. ncbi request reprint Covariates of cervical cytokine mRNA expression by real-time PCR in adolescents and young women: effects of Chlamydia trachomatis infection, hormonal contraception, and smoking
    Mark E Scott
    Department of Pediatrics, Division of Adolescent Medicine, University of California, San Francisco, California 94143 1374, USA
    J Clin Immunol 26:222-32. 2006
  2. pmc Interlaboratory reproducibility of female genital tract cytokine measurements by Luminex: implications for microbicide safety studies
    Mark E Scott
    Division of Adolescent Medicine, Department of Pediatrics, School of Medicine, University of California, San Francisco, 513 Parnassus Avenue, San Francisco, CA 94143, USA
    Cytokine 56:430-4. 2011
  3. pmc Measurement of mucosal biomarkers in a phase 1 trial of intravaginal 3% StarPharma LTD 7013 gel (VivaGel) to assess expanded safety
    Anna Barbara Moscicki
    Department of Pediatrics, University of California, San Francisco, CA 94118, USA
    J Acquir Immune Defic Syndr 59:134-40. 2012
  4. pmc Association between toll-like receptor expression and human papillomavirus type 16 persistence
    Ibrahim I Daud
    Infectious Disease Research Training Program, University of California, San Francisco, CA 94118, USA
    Int J Cancer 128:879-86. 2011
  5. pmc Determination of cytokine protein levels in cervical mucus samples from young women by a multiplex immunoassay method and assessment of correlates
    Jay A Lieberman
    Division of Adolescent Medicine, Department of Pediatrics, University of California, San Francisco, California 94143, USA
    Clin Vaccine Immunol 15:49-54. 2008
  6. pmc Diminished IFN-gamma and IL-10 and elevated Foxp3 mRNA expression in the cervix are associated with CIN 2 or 3
    Mark E Scott
    Department of Pediatrics, University of California, San Francisco, CA 94143 1374, USA
    Int J Cancer 124:1379-83. 2009
  7. pmc Increased levels of immune activation in the genital tract of healthy young women from sub-Saharan Africa
    Craig R Cohen
    Department of Obstetrics, Gynecology and Reproductive Sciences, University of California, San Francisco, California 94117, USA
    AIDS 24:2069-74. 2010
  8. pmc Higher levels of cervicovaginal inflammatory and regulatory cytokines and chemokines in healthy young women with immature cervical epithelium
    Loris Y Hwang
    University of California San Francisco, Department of Pediatrics, Division of Adolescent Medicine, 3333 California Street, Suite 245, San Francisco, CA 94118, USA
    J Reprod Immunol 88:66-71. 2011
  9. pmc Cervical cytokines and clearance of incident human papillomavirus infection: Hawaii HPV cohort study
    Mark E Scott
    Division of Adolescent Medicine, Department of Pediatrics, University of California, San Francisco, San Francisco, CA
    Int J Cancer 133:1187-96. 2013

Detail Information

Publications9

  1. ncbi request reprint Covariates of cervical cytokine mRNA expression by real-time PCR in adolescents and young women: effects of Chlamydia trachomatis infection, hormonal contraception, and smoking
    Mark E Scott
    Department of Pediatrics, Division of Adolescent Medicine, University of California, San Francisco, California 94143 1374, USA
    J Clin Immunol 26:222-32. 2006
    ..Time since last menstrual period did not affect any of the cytokines; in a substudy of weekly cytokine variability, however, IL-10 showed a non-significant trend toward higher levels around the time of menstruation...
  2. pmc Interlaboratory reproducibility of female genital tract cytokine measurements by Luminex: implications for microbicide safety studies
    Mark E Scott
    Division of Adolescent Medicine, Department of Pediatrics, School of Medicine, University of California, San Francisco, 513 Parnassus Avenue, San Francisco, CA 94143, USA
    Cytokine 56:430-4. 2011
    ....
  3. pmc Measurement of mucosal biomarkers in a phase 1 trial of intravaginal 3% StarPharma LTD 7013 gel (VivaGel) to assess expanded safety
    Anna Barbara Moscicki
    Department of Pediatrics, University of California, San Francisco, CA 94118, USA
    J Acquir Immune Defic Syndr 59:134-40. 2012
    ..The aim of this study was to examine the effect of the 3% StarPharma LTD 7013 gel (VivaGel) on mucosal immune markers hypothesized to be associated with HIV-1 acquisition...
  4. pmc Association between toll-like receptor expression and human papillomavirus type 16 persistence
    Ibrahim I Daud
    Infectious Disease Research Training Program, University of California, San Francisco, CA 94118, USA
    Int J Cancer 128:879-86. 2011
    ....
  5. pmc Determination of cytokine protein levels in cervical mucus samples from young women by a multiplex immunoassay method and assessment of correlates
    Jay A Lieberman
    Division of Adolescent Medicine, Department of Pediatrics, University of California, San Francisco, California 94143, USA
    Clin Vaccine Immunol 15:49-54. 2008
    ..Cigarette smoking appears to downregulate cytokine responses in the cervical mucosa, which may help explain the implicated role of tobacco use as a cofactor for cervical cancer development...
  6. pmc Diminished IFN-gamma and IL-10 and elevated Foxp3 mRNA expression in the cervix are associated with CIN 2 or 3
    Mark E Scott
    Department of Pediatrics, University of California, San Francisco, CA 94143 1374, USA
    Int J Cancer 124:1379-83. 2009
    ..05). These findings support a model in which diminished cellular immunity in the cervical mucosa and mucosal enrichment of Treg cells both contribute to the development of high-grade lesions...
  7. pmc Increased levels of immune activation in the genital tract of healthy young women from sub-Saharan Africa
    Craig R Cohen
    Department of Obstetrics, Gynecology and Reproductive Sciences, University of California, San Francisco, California 94117, USA
    AIDS 24:2069-74. 2010
    ..To determine whether healthy, young women in sub-Saharan Africa have a more activated immune milieu in the genital tract (i.e. activated CD4 T cells) than a similar population in the United States...
  8. pmc Higher levels of cervicovaginal inflammatory and regulatory cytokines and chemokines in healthy young women with immature cervical epithelium
    Loris Y Hwang
    University of California San Francisco, Department of Pediatrics, Division of Adolescent Medicine, 3333 California Street, Suite 245, San Francisco, CA 94118, USA
    J Reprod Immunol 88:66-71. 2011
    ..Cytokine profiles in the healthy state may foreshadow differential responses to pathogens. Cervical epithelial type should be measured in clinical studies involving cervicovaginal immune markers...
  9. pmc Cervical cytokines and clearance of incident human papillomavirus infection: Hawaii HPV cohort study
    Mark E Scott
    Division of Adolescent Medicine, Department of Pediatrics, University of California, San Francisco, San Francisco, CA
    Int J Cancer 133:1187-96. 2013
    ..Our results suggest that in women with a nontransient cervical HPV infection, proinflammatory, Type-1, and regulatory cytokines are elevated, underscoring the long-term commitment of local immune mediators to viral eradication. ..