Mark E Scott

Summary

Affiliation: University of California
Country: USA

Publications

  1. pmc Cervical cytokines and clearance of incident human papillomavirus infection: Hawaii HPV cohort study
    Mark E Scott
    Division of Adolescent Medicine, Department of Pediatrics, University of California, San Francisco, San Francisco, CA 94143 1374, USA
    Int J Cancer 133:1187-96. 2013
  2. ncbi request reprint Covariates of cervical cytokine mRNA expression by real-time PCR in adolescents and young women: effects of Chlamydia trachomatis infection, hormonal contraception, and smoking
    Mark E Scott
    Department of Pediatrics, Division of Adolescent Medicine, University of California, San Francisco, California 94143 1374, USA
    J Clin Immunol 26:222-32. 2006
  3. pmc Interlaboratory reproducibility of female genital tract cytokine measurements by Luminex: implications for microbicide safety studies
    Mark E Scott
    Division of Adolescent Medicine, Department of Pediatrics, School of Medicine, University of California, San Francisco, 513 Parnassus Avenue, San Francisco, CA 94143, USA
    Cytokine 56:430-4. 2011
  4. pmc Measurement of mucosal biomarkers in a phase 1 trial of intravaginal 3% StarPharma LTD 7013 gel (VivaGel) to assess expanded safety
    Anna Barbara Moscicki
    Department of Pediatrics, University of California, San Francisco, CA 94118, USA
    J Acquir Immune Defic Syndr 59:134-40. 2012
  5. pmc Association between toll-like receptor expression and human papillomavirus type 16 persistence
    Ibrahim I Daud
    Infectious Disease Research Training Program, University of California, San Francisco, CA 94118, USA
    Int J Cancer 128:879-86. 2011
  6. pmc Determination of cytokine protein levels in cervical mucus samples from young women by a multiplex immunoassay method and assessment of correlates
    Jay A Lieberman
    Division of Adolescent Medicine, Department of Pediatrics, University of California, San Francisco, California 94143, USA
    Clin Vaccine Immunol 15:49-54. 2008
  7. pmc Diminished IFN-gamma and IL-10 and elevated Foxp3 mRNA expression in the cervix are associated with CIN 2 or 3
    Mark E Scott
    Department of Pediatrics, University of California, San Francisco, CA 94143 1374, USA
    Int J Cancer 124:1379-83. 2009
  8. pmc Increased levels of immune activation in the genital tract of healthy young women from sub-Saharan Africa
    Craig R Cohen
    Department of Obstetrics, Gynecology and Reproductive Sciences, University of California, San Francisco, California 94117, USA
    AIDS 24:2069-74. 2010
  9. pmc Higher levels of cervicovaginal inflammatory and regulatory cytokines and chemokines in healthy young women with immature cervical epithelium
    Loris Y Hwang
    University of California San Francisco, Department of Pediatrics, Division of Adolescent Medicine, 3333 California Street, Suite 245, San Francisco, CA 94118, USA
    J Reprod Immunol 88:66-71. 2011

Detail Information

Publications9

  1. pmc Cervical cytokines and clearance of incident human papillomavirus infection: Hawaii HPV cohort study
    Mark E Scott
    Division of Adolescent Medicine, Department of Pediatrics, University of California, San Francisco, San Francisco, CA 94143 1374, USA
    Int J Cancer 133:1187-96. 2013
    ..Our results suggest that in women with a nontransient cervical HPV infection, proinflammatory, Type-1, and regulatory cytokines are elevated, underscoring the long-term commitment of local immune mediators to viral eradication. ..
  2. ncbi request reprint Covariates of cervical cytokine mRNA expression by real-time PCR in adolescents and young women: effects of Chlamydia trachomatis infection, hormonal contraception, and smoking
    Mark E Scott
    Department of Pediatrics, Division of Adolescent Medicine, University of California, San Francisco, California 94143 1374, USA
    J Clin Immunol 26:222-32. 2006
    ..Time since last menstrual period did not affect any of the cytokines; in a substudy of weekly cytokine variability, however, IL-10 showed a non-significant trend toward higher levels around the time of menstruation...
  3. pmc Interlaboratory reproducibility of female genital tract cytokine measurements by Luminex: implications for microbicide safety studies
    Mark E Scott
    Division of Adolescent Medicine, Department of Pediatrics, School of Medicine, University of California, San Francisco, 513 Parnassus Avenue, San Francisco, CA 94143, USA
    Cytokine 56:430-4. 2011
    ....
  4. pmc Measurement of mucosal biomarkers in a phase 1 trial of intravaginal 3% StarPharma LTD 7013 gel (VivaGel) to assess expanded safety
    Anna Barbara Moscicki
    Department of Pediatrics, University of California, San Francisco, CA 94118, USA
    J Acquir Immune Defic Syndr 59:134-40. 2012
    ..The aim of this study was to examine the effect of the 3% StarPharma LTD 7013 gel (VivaGel) on mucosal immune markers hypothesized to be associated with HIV-1 acquisition...
  5. pmc Association between toll-like receptor expression and human papillomavirus type 16 persistence
    Ibrahim I Daud
    Infectious Disease Research Training Program, University of California, San Francisco, CA 94118, USA
    Int J Cancer 128:879-86. 2011
    ....
  6. pmc Determination of cytokine protein levels in cervical mucus samples from young women by a multiplex immunoassay method and assessment of correlates
    Jay A Lieberman
    Division of Adolescent Medicine, Department of Pediatrics, University of California, San Francisco, California 94143, USA
    Clin Vaccine Immunol 15:49-54. 2008
    ..Cigarette smoking appears to downregulate cytokine responses in the cervical mucosa, which may help explain the implicated role of tobacco use as a cofactor for cervical cancer development...
  7. pmc Diminished IFN-gamma and IL-10 and elevated Foxp3 mRNA expression in the cervix are associated with CIN 2 or 3
    Mark E Scott
    Department of Pediatrics, University of California, San Francisco, CA 94143 1374, USA
    Int J Cancer 124:1379-83. 2009
    ..05). These findings support a model in which diminished cellular immunity in the cervical mucosa and mucosal enrichment of Treg cells both contribute to the development of high-grade lesions...
  8. pmc Increased levels of immune activation in the genital tract of healthy young women from sub-Saharan Africa
    Craig R Cohen
    Department of Obstetrics, Gynecology and Reproductive Sciences, University of California, San Francisco, California 94117, USA
    AIDS 24:2069-74. 2010
    ..To determine whether healthy, young women in sub-Saharan Africa have a more activated immune milieu in the genital tract (i.e. activated CD4 T cells) than a similar population in the United States...
  9. pmc Higher levels of cervicovaginal inflammatory and regulatory cytokines and chemokines in healthy young women with immature cervical epithelium
    Loris Y Hwang
    University of California San Francisco, Department of Pediatrics, Division of Adolescent Medicine, 3333 California Street, Suite 245, San Francisco, CA 94118, USA
    J Reprod Immunol 88:66-71. 2011
    ..Cytokine profiles in the healthy state may foreshadow differential responses to pathogens. Cervical epithelial type should be measured in clinical studies involving cervicovaginal immune markers...