Research Topics
Species | B T ScottSummaryAffiliation: University of Vermont Country: USA Publications
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Detail Information
Publications
Characterization of the human prostaglandin H synthase 1 gene (PTGS1): exclusion by genetic linkage analysis as a second modifier gene in familial thrombosisB T Scott
Department of Pathology, University of Vermont, Burlington 05405, USA
Blood Coagul Fibrinolysis 13:519-31. 2002..Linkage analysis of the SNP and STR markers indicated that PTGS1 is not the interacting gene associated with an increased incidence of thrombosis in the Vermont kindred...
Genetic screening of candidate genes for a prothrombotic interaction with type I protein C deficiency in a large kindredB T Scott
Department of Pathology, University of Vermont, Burlington 05405, USA
Thromb Haemost 85:82-7. 2001..However, linkage analysis provided no evidence to implicate any of the candidate genes as the second inherited factor that promotes thrombophilia in this kindred...
The G20210A prothrombin polymorphism is not associated with increased thromboembolic risk in a large protein C deficient kindredE G Bovill
Department of Pathology, University of Vermont, Burlington 05405, USA
Thromb Haemost 83:366-70. 2000..These findings contrast with those of others who have established the G20210A variant as a thrombophilic risk factor; and emphasize the complex nature of the multigenic pathogenesis of thrombophilia...
Heritability of plasma concentrations of clotting factors and measures of a prethrombotic state in a protein C-deficient familyC Y Vossen
Pathology, University of Vermont, Burlington, VT 05405, USA
J Thromb Haemost 2:242-7. 2004..Hemostatic markers with statistically significant heritability constitute potential targets for the identification of novel genes involved in the control of quantitative trait loci...
Purification and complete sequence determination of the major plasma membrane substrate for cAMP-dependent protein kinase and protein kinase C in myocardiumC J Palmer
Krannert Institute of Cardiology, Indiana University School of Medicine, Indianapolis 46202
J Biol Chem 266:11126-30. 1991..We propose the name "phospholemman" for the 15-kDa protein, which denotes the protein's location within the plasma membrane and its characteristic multisite phosphorylation...
Genome scan of venous thrombosis in a pedigree with protein C deficiencyS J Hasstedt
Department of Human Genetics, University of Utah, Salt Lake City, UT 84112 5330, USA
J Thromb Haemost 2:868-73. 2004..Identification of the unknown mutation(s) promises to reveal a new genetic risk factor for thrombophilia, contribute to our understanding of the blood clotting mechanism, and expand our knowledge of the diversity of oligogenic disease...
A genome search for genetic determinants of markers of protein C activationC Y Vossen
J Thromb Haemost 4:706-8. 2006
