Rebecca E Schweppe

Summary

Affiliation: University of Colorado Denver
Country: USA

Publications

  1. pmc Deoxyribonucleic acid profiling analysis of 40 human thyroid cancer cell lines reveals cross-contamination resulting in cell line redundancy and misidentification
    Rebecca E Schweppe
    Division of Endocrinology, Diabetes and Metabolism, Department of Medicine and University of Colorado Cancer Center, Denver, Aurora, Colorado 80045, USA
    J Clin Endocrinol Metab 93:4331-41. 2008
  2. pmc Inhibition of Src with AZD0530 reveals the Src-Focal Adhesion kinase complex as a novel therapeutic target in papillary and anaplastic thyroid cancer
    Rebecca E Schweppe
    Division of Endocrinology, Diabetes, and Metabolism, University of Colorado Denver, Aurora, Colorado 80045, USA
    J Clin Endocrinol Metab 94:2199-203. 2009
  3. pmc Distinct genetic alterations in the mitogen-activated protein kinase pathway dictate sensitivity of thyroid cancer cells to mitogen-activated protein kinase kinase 1/2 inhibition
    Rebecca E Schweppe
    University of Colorado Denver, Aurora, 80045, USA
    Thyroid 19:825-35. 2009
  4. doi request reprint Targeted inhibition of Src kinase with dasatinib blocks thyroid cancer growth and metastasis
    Christine M Chan
    Division of Endocrinology, Metabolism, and Diabetes, Department of Medicine, University of Colorado School of Medicine, Aurora, Colorado 80045, USA
    Clin Cancer Res 18:3580-91. 2012
  5. pmc Inhibition of nuclear factor-kappa B differentially affects thyroid cancer cell growth, apoptosis, and invasion
    Kevin T Bauerle
    Department of Medicine, Division of Endocrinology, Metabolism, and Diabetes, University of Colorado, Research Complex I, South Tower, Mail Stop 8106, 12801 East 17th Avenue, PO Box 6511, Aurora, CO 80045, USA
    Mol Cancer 9:117. 2010
  6. pmc PPARγ Promotes Growth and Invasion of Thyroid Cancer Cells
    William M Wood
    Division of Endocrinology, Metabolism and Diabetes, Department of Medicine, University of Colorado Denver, Aurora, CO 80045, USA
    PPAR Res 2011:171765. 2011

Collaborators

Detail Information

Publications6

  1. pmc Deoxyribonucleic acid profiling analysis of 40 human thyroid cancer cell lines reveals cross-contamination resulting in cell line redundancy and misidentification
    Rebecca E Schweppe
    Division of Endocrinology, Diabetes and Metabolism, Department of Medicine and University of Colorado Cancer Center, Denver, Aurora, Colorado 80045, USA
    J Clin Endocrinol Metab 93:4331-41. 2008
    ..Cell lines derived from human cancers provide critical tools to study disease mechanisms and develop novel therapies. Recent reports indicate that up to 36% of cell lines are cross- contaminated...
  2. pmc Inhibition of Src with AZD0530 reveals the Src-Focal Adhesion kinase complex as a novel therapeutic target in papillary and anaplastic thyroid cancer
    Rebecca E Schweppe
    Division of Endocrinology, Diabetes, and Metabolism, University of Colorado Denver, Aurora, Colorado 80045, USA
    J Clin Endocrinol Metab 94:2199-203. 2009
    ..The role of the Src-FAK complex has not been characterized in papillary and anaplastic thyroid cancer (PTC and ATC)...
  3. pmc Distinct genetic alterations in the mitogen-activated protein kinase pathway dictate sensitivity of thyroid cancer cells to mitogen-activated protein kinase kinase 1/2 inhibition
    Rebecca E Schweppe
    University of Colorado Denver, Aurora, 80045, USA
    Thyroid 19:825-35. 2009
    ....
  4. doi request reprint Targeted inhibition of Src kinase with dasatinib blocks thyroid cancer growth and metastasis
    Christine M Chan
    Division of Endocrinology, Metabolism, and Diabetes, Department of Medicine, University of Colorado School of Medicine, Aurora, Colorado 80045, USA
    Clin Cancer Res 18:3580-91. 2012
    ..We recently showed that Src is overexpressed and activated in thyroid cancer. We therefore tested whether inhibition of Src with dasatinib (BMS-354825) blocks thyroid cancer growth and metastasis...
  5. pmc Inhibition of nuclear factor-kappa B differentially affects thyroid cancer cell growth, apoptosis, and invasion
    Kevin T Bauerle
    Department of Medicine, Division of Endocrinology, Metabolism, and Diabetes, University of Colorado, Research Complex I, South Tower, Mail Stop 8106, 12801 East 17th Avenue, PO Box 6511, Aurora, CO 80045, USA
    Mol Cancer 9:117. 2010
    ..In this study, we have investigated the role of NF-kappaB signaling in thyroid cancer cell proliferation, invasion, and apoptosis using selective genetic inhibition of NF-kappaB in advanced thyroid cancer cell lines...
  6. pmc PPARγ Promotes Growth and Invasion of Thyroid Cancer Cells
    William M Wood
    Division of Endocrinology, Metabolism and Diabetes, Department of Medicine, University of Colorado Denver, Aurora, CO 80045, USA
    PPAR Res 2011:171765. 2011
    ..These data suggest that PPARγ may play a detrimental role in thyroid cancer and that targeting it therapeutically may lead to improved treatment of advanced thyroid cancer...