Stephen G Schwartz

Summary

Affiliation: University of Miami
Country: USA

Publications

  1. doi request reprint Ruboxistaurin mesilate hydrate for diabetic retinopathy
    Stephen G Schwartz
    Department of Ophthalmology, Bascom Palmer Eye Institute, University of Miami Miller School of Medicine, Naples, FL, USA
    Drugs Today (Barc) 45:269-74. 2009
  2. doi request reprint "Floater scotoma" demonstrated on spectral-domain optical coherence tomography and caused by vitreous opacification
    Stephen G Schwartz
    Department of Ophthalmology, Bascom Palmer Eye Institute, University of Miami Miller School of Medicine, Miami, Florida 34102, USA
    Ophthalmic Surg Lasers Imaging Retina 44:415-8. 2013
  3. doi request reprint Congenital hypertrophy of the retinal pigment epithelium: choroidal cavitation demonstrated on spectral-domain OCT
    Stephen G Schwartz
    Department of Ophthalmology, Bascom Palmer Eye Institute, University of Miami Miller School of Medicine, Miami, Florida 34102, USA
    Ophthalmic Surg Lasers Imaging Retina 44:301-2. 2013
  4. ncbi request reprint Genetics and diabetic retinopathy
    Stephen G Schwartz
    Bascom Palmer Eye Institute at Naples, 311 9th Street North 100, Naples, FL 34102, USA
    Curr Diabetes Rev 9:86-92. 2013
  5. doi request reprint The ARMS2 A69S variant and bilateral advanced age-related macular degeneration
    Stephen G Schwartz
    Bascom Palmer Eye Institute, University of Miami Miller School of Medicine, Miami, Florida, USA
    Retina 32:1486-91. 2012
  6. doi request reprint Endophthalmitis after intravitreal injections
    Stephen G Schwartz
    University of Miami Miller School of Medicine, Bascom Palmer Eye Institute at Naples, Naples, FL 34102, USA
    Expert Opin Pharmacother 10:2119-26. 2009
  7. ncbi request reprint Pharmacotherapy for diabetic retinopathy
    Stephen G Schwartz
    University of Miami Miller School of Medicine, Bascom Palmer Eye Institute, 311 9th Street North, 100, Naples, FL 34102, USA
    Expert Opin Pharmacother 10:1123-31. 2009
  8. ncbi request reprint Fluocinolone acetonide implantable device for diabetic retinopathy
    Stephen G Schwartz
    Department of Ophthalmology, Bascom Palmer Eye Institute, University of Miami Miller School of Medicine, FL, USA
    Curr Pharm Biotechnol 12:347-51. 2011
  9. pmc Pharmacotherapies for diabetic retinopathy: present and future
    Stephen G Schwartz
    Bascom Palmer Eye Institute, Retina Center at Naples, 311 9th Street North, Naples, FL 34102, USA
    Exp Diabetes Res 2007:52487. 2007
  10. ncbi request reprint Beta1-adrenergic receptor polymorphisms and clinical efficacy of betaxolol hydrochloride in normal volunteers
    Stephen G Schwartz
    Bascom Palmer Eye Institute, University of Miami Miller School of Medicine, Miami, Florida 34102, USA
    Ophthalmology 112:2131-6. 2005

Collaborators

Detail Information

Publications37

  1. doi request reprint Ruboxistaurin mesilate hydrate for diabetic retinopathy
    Stephen G Schwartz
    Department of Ophthalmology, Bascom Palmer Eye Institute, University of Miami Miller School of Medicine, Naples, FL, USA
    Drugs Today (Barc) 45:269-74. 2009
    ..The U.S. Food and Drug Administration issued an approvable letter for ruboxistaurin in 2006, but at this time the medication is not available for routine clinical use...
  2. doi request reprint "Floater scotoma" demonstrated on spectral-domain optical coherence tomography and caused by vitreous opacification
    Stephen G Schwartz
    Department of Ophthalmology, Bascom Palmer Eye Institute, University of Miami Miller School of Medicine, Miami, Florida 34102, USA
    Ophthalmic Surg Lasers Imaging Retina 44:415-8. 2013
    ..This finding may be useful in objectively documenting the status of vitreous opacification and verifying the patient's complaint of symptomatic floaters, a so-called "floater scotoma"...
  3. doi request reprint Congenital hypertrophy of the retinal pigment epithelium: choroidal cavitation demonstrated on spectral-domain OCT
    Stephen G Schwartz
    Department of Ophthalmology, Bascom Palmer Eye Institute, University of Miami Miller School of Medicine, Miami, Florida 34102, USA
    Ophthalmic Surg Lasers Imaging Retina 44:301-2. 2013
    ..Although photoreceptor atrophy overlying congenital hypertrophy of the retinal pigment epithelium has been described on time-domain OCT, this patient manifested a previously unrecognized tomographic feature...
  4. ncbi request reprint Genetics and diabetic retinopathy
    Stephen G Schwartz
    Bascom Palmer Eye Institute at Naples, 311 9th Street North 100, Naples, FL 34102, USA
    Curr Diabetes Rev 9:86-92. 2013
    ..This may be due to small sample sizes, differences in study design, underlying genetic differences between study populations, or other factors. As we continue to collect data, these relationships may become more clear...
  5. doi request reprint The ARMS2 A69S variant and bilateral advanced age-related macular degeneration
    Stephen G Schwartz
    Bascom Palmer Eye Institute, University of Miami Miller School of Medicine, Miami, Florida, USA
    Retina 32:1486-91. 2012
    ....
  6. doi request reprint Endophthalmitis after intravitreal injections
    Stephen G Schwartz
    University of Miami Miller School of Medicine, Bascom Palmer Eye Institute at Naples, Naples, FL 34102, USA
    Expert Opin Pharmacother 10:2119-26. 2009
    ..Infectious endophthalmitis must be differentiated from noninfectious inflammation. Depending on the series, the risk of endophthalmitis is very low. The use of a standardized injection protocol can reduce the risk of infection...
  7. ncbi request reprint Pharmacotherapy for diabetic retinopathy
    Stephen G Schwartz
    University of Miami Miller School of Medicine, Bascom Palmer Eye Institute, 311 9th Street North, 100, Naples, FL 34102, USA
    Expert Opin Pharmacother 10:1123-31. 2009
    ..Although no agent is now approved by the FDA for this purpose, many agents are now being studied in randomized clinical trials (RCTs)...
  8. ncbi request reprint Fluocinolone acetonide implantable device for diabetic retinopathy
    Stephen G Schwartz
    Department of Ophthalmology, Bascom Palmer Eye Institute, University of Miami Miller School of Medicine, FL, USA
    Curr Pharm Biotechnol 12:347-51. 2011
    ..Combination photocoagulation and pharmacotherapy with these devices has not yet been reported...
  9. pmc Pharmacotherapies for diabetic retinopathy: present and future
    Stephen G Schwartz
    Bascom Palmer Eye Institute, Retina Center at Naples, 311 9th Street North, Naples, FL 34102, USA
    Exp Diabetes Res 2007:52487. 2007
    ..Other medications under investigation include the fluocinolone acetonide implantable device, extended-release dexamethasone implant, oral ruboxistaurin, and intravitreal hyaluronidase...
  10. ncbi request reprint Beta1-adrenergic receptor polymorphisms and clinical efficacy of betaxolol hydrochloride in normal volunteers
    Stephen G Schwartz
    Bascom Palmer Eye Institute, University of Miami Miller School of Medicine, Miami, Florida 34102, USA
    Ophthalmology 112:2131-6. 2005
    ..To evaluate the relationship between polymorphisms in the gene encoding the beta1-adrenergic receptor (beta1-AR) and clinical response to betaxolol hydrochloride 0.25% in a small pilot study of normal volunteers...
  11. doi request reprint Long-term safety and efficacy of intravitreal bevacizumab (Avastin) for the management of central retinal vein occlusion
    Ninel Z Gregori
    Department of Ophthalmology, Bascom Palmer Eye Institute, University of Miami Miller School of Medicine, 900 NW 17th St, Miami, FL 33136, USA
    Retina 28:1325-37. 2008
    ..To evaluate the long-term safety and efficacy of intravitreal bevacizumab injections (Avastin, Genentech Inc., San Francisco, CA) for the treatment of macular edema secondary to central retinal vein occlusions...
  12. doi request reprint Endophthalmitis after intravitreal vascular [corrected] endothelial growth factor antagonists: a six-year experience at a university referral center
    Andrew A Moshfeghi
    Bascom Palmer Eye Institute, Department of Ophthalmology, University of Miami Miller School of Medicine, Miami, Florida 33418, USA
    Retina 31:662-8. 2011
    ....
  13. doi request reprint Variants at chromosome 10q26 locus and the expression of HTRA1 in the retina
    Gaofeng Wang
    John P Hussman Institute for Human Genomics, University of Miami Miller School of Medicine, Miami, FL 33136, USA
    Exp Eye Res 112:102-5. 2013
    ..These results suggest that the AMD-associated variants in the chromosome 10q26 locus do not significantly affect the expression of HTRA1. ..
  14. ncbi request reprint Thirty-two month follow-up of successful treatment of choroidal neovascularization from angioid streaks with intravitreal bevacizumab
    Jaclyn L Kovach
    Bascom Palmer Eye Institute, Retina Center at Naples, 311 9th Street North, 100, Naples, FL 34102, USA
    Ophthalmic Surg Lasers Imaging 40:77-9. 2009
    ..In certain patients with choroidal neovascularization from angioid streaks, intravitreal bevacizumab may produce normalization of visual acuity and macular anatomy for an extended period of time...
  15. doi request reprint Glucocorticoid receptor polymorphisms and intraocular pressure response to intravitreal triamcinolone acetonide
    Sabrina M Gerzenstein
    Bascom Palmer Eye Institute, University of Miami Miller School of Medicine, Miami, Florida, USA
    Ophthalmic Genet 29:166-70. 2008
    ..The etiology of the steroid response is poorly understood, although a genetic determinant has long been suspected. We performed a pharmacogenomic association study with glucocorticoid receptor polymorphisms...
  16. pmc Inverse association of female hormone replacement therapy with age-related macular degeneration and interactions with ARMS2 polymorphisms
    Digna R Velez Edwards
    Dr John T Macdonald Foundation Department of Human Genetics and John P Hussman Institute for Human Genomics, Miller School of Medicine, University of Miami, Miami, Florida, USA
    Invest Ophthalmol Vis Sci 51:1873-9. 2010
    ..These results highlight the genetic and environmental complexity of the etiologic architecture of AMD; however, further replication is necessary to validate them...
  17. doi request reprint Safety and efficacy of intravitreal bevacizumab (avastin) for the management of branch and hemiretinal vein occlusion
    Ninel Z Gregori
    Department of Ophthalmology, Bascom Palmer Eye Institute, University of Miami Miller School of Medicine, Miami, Florida 33136, USA
    Retina 29:913-25. 2009
    ..To evaluate the safety and efficacy of intravitreal bevacizumab (Avastin, Genentech) for the treatment of macular edema (ME) secondary to branch retinal vein occlusion (BRVO) and hemiretinal vein occlusion (HRVO)...
  18. pmc Analysis of single nucleotide polymorphisms in the NOS2A gene and interaction with smoking in age-related macular degeneration
    Juan A Ayala-Haedo
    John P Hussman Institute for Human Genomics and the Dr John T Macdonald Foundation Department of Human Genetics, University of Miami Miller School of Medicine, Miami, FL 33136, USA
    Ann Hum Genet 74:195-201. 2010
    ..Our data suggests that SNPs in the NOS2A gene are associated with increased risk for AMD and might modulate the effect of smoking on AMD...
  19. doi request reprint Fovea-sparing retinal detachments: time to surgery and visual outcomes
    Charles C Wykoff
    Department of Ophthalmology, Bascom Palmer Eye Institute, University of Miami Miller School of Medicine, 900 NW 17th Street, Miami, FL 33136, USA
    Am J Ophthalmol 150:205-210.e2. 2010
    ..To study the effect of the duration from initial evaluation to repair on outcomes for fovea-sparing rhegmatogenous retinal detachment (RRD)...
  20. doi request reprint Initial outcomes following intravitreal ocriplasmin for treatment of symptomatic vitreomacular adhesion
    Brian T Kim
    Department of Ophthalmology, Bascom Palmer Eye Institute, University of Miami Miller School of Medicine, Miami, Florida, USA
    Ophthalmic Surg Lasers Imaging Retina 44:334-43. 2013
    ..The authors describe their initial clinical experience with ocriplasmin at a large academic center...
  21. pmc Analysis of the indel at the ARMS2 3'UTR in age-related macular degeneration
    Gaofeng Wang
    Dr John T Macdonald Foundation Department of Human Genetics, John P Hussman Institute for Human Genomics, University of Miami Miller School of Medicine, Miami, FL 33136, USA
    Hum Genet 127:595-602. 2010
    ..Conclusively, the indel at 3'UTR of ARMS2 actually contains two side-by-side indels. The indels are associated with risk of AMD, but not correlated with ARMS2 mRNA level...
  22. doi request reprint Update on retinal detachment surgery
    Stephen G Schwartz
    Bascom Palmer Eye Institute, University of Miami Miller School of Medicine, 900 NW 17 Street, Miami, FL 33136, USA
    Curr Opin Ophthalmol 24:255-61. 2013
    ..Update on controversies in the surgical management of rhegmatogenous retinal detachment...
  23. ncbi request reprint Bilateral CRAO and CRVO from thrombotic thrombocytopenic purpura: OCT findings and treatment with triamcinolone acetonide and bevacizumab
    Stephen G Schwartz
    Bascom Palmer Eye Institute, Department of Ophthalmology, University of Miami Miller School of Medicine, Miami, Florida 34102, USA
    Ophthalmic Surg Lasers Imaging 37:420-2. 2006
    ..Treatment of both eyes with intravitreal bevacizumab (1.25 mg) and panretinal photocoagulation was effective in eliminating iris neovascularization, although the patient lost all visual function...
  24. ncbi request reprint Lack of toxicity of stainless steel retinal tacks during 21 years of follow-up
    Golnaz Javey
    Department of Ophthalmology, Bascom Palmer Eye Institute, University of Miami Miller School of Medicine, Miami, Florida, USA
    Ophthalmic Surg Lasers Imaging 40:75-6. 2009
    ..Although retinal tacks are no longer used, this case report suggests that intraocular stainless steel may cause minimal or no retinal toxicity during long-term follow-up...
  25. doi request reprint Comparison of intravitreal bevacizumab followed by ranibizumab for the treatment of neovascular age-related macular degeneration
    Kimberly E Stepien
    Department of Ophthalmology, Bascom Palmer Eye Institute, University of Miami School of Medicine, Miami, Florida 33136, USA
    Retina 29:1067-73. 2009
    ..To compare outcomes after switching from intravitreal bevacizumab (Avastin) to ranibizumab (Lucentis) in patients with neovascular age-related macular degeneration (AMD)...
  26. pmc Emerging pharmacotherapies for diabetic macular edema
    Golnaz Javey
    Department of Ophthalmology, Baylor College of Medicine, 7200 B Cambridge Street, Houston, TX 77030, USA
    Exp Diabetes Res 2012:548732. 2012
    ..Pharmacotherapies for DME include locally and systemically administered agents. We review several agents that have been studied for the treatment of DME...
  27. ncbi request reprint Primary retinal detachment: scleral buckle or pars plana vitrectomy?
    Stephen G Schwartz
    Department of Ophthalmology, Bascom Palmer Eye Institute, University of Miami Miller School of Medicine, Miami, Florida 33136, USA
    Curr Opin Ophthalmol 17:245-50. 2006
    ..There remains no consensus among vitreoretinal surgeons regarding the optimal management of primary rhegmatogenous retinal detachment. In this article, fundamental principles are discussed and applied to recent clinical reports...
  28. ncbi request reprint Medications and retinal toxicity
    Stephen G Schwartz
    Department of Ophthalmology, Medical College of Virginia, Commonwealth University, 8th Floor, MCV Box 980262, 1101 E Marshall Street, Richmond, VA 23298 0262, USA
    Ophthalmol Clin North Am 15:517-28. 2002
    ..When assessing any patient for a retinal disturbance, it is imperative to question the patient regarding the use of systemic medications. This is especially important as more and more medications are brought to the market each year...
  29. pmc Anti-VEGF Treatment Strategies for Wet AMD
    Jaclyn L Kovach
    Department of Ophthalmology, Bascom Palmer Eye Institute, School of Medicine, University of Miami, 311 9th St North, Naples, FL 34102, USA
    J Ophthalmol 2012:786870. 2012
    ..During this time, treatment strategies have evolved from a monthly dosing schedule to individualized regimens. This paper will review the currently available anti-VEGF agents and evidence-based treatment strategies...
  30. doi request reprint Drug delivery techniques for treating age-related macular degeneration
    Stephen G Schwartz
    University of Miami Miller School of Medicine, Bascom Palmer Eye Institute, 311 9th Street North, Naples, 34102, USA
    Expert Opin Drug Deliv 11:61-8. 2014
    ..In addition, the cumulative risks of endophthalmitis and other complications increase with the number of injections...
  31. pmc Methicillin-resistant Staphylococcus epidermidis isolation from the vitrectomy specimen four hours after initial treatment with vancomycin and ceftazidime
    Golnaz Javey
    Department of Ophthalmology, Cullen Eye Institute, Baylor College of Medicine, Houston, TX, USA
    Clin Ophthalmol 4:101-4. 2010
    ..This case illustrates the time lag necessary to sterilize the vitreous cavity, and suggests a possible two-step staged treatment strategy for situations in which access to PPV equipment and support staff may be limited...
  32. ncbi request reprint Choroideremia with polydactyly mimicking the Laurence-Moon-Bardet-Biedl syndrome
    Stephen G Schwartz
    Department of Ophthalmology, Virginia Commonwealth University, Medical College of Virginia Campus, Richmond, Virginia 23298 0262, USA
    Retina 23:413-5. 2003
  33. pmc Pharmacogenetics and age-related macular degeneration
    Stephen G Schwartz
    Bascom Palmer Eye Institute, Miller School of Medicine, University of Miami, 311 9th Street North, No 100, Naples, FL 34102, USA
    J Ophthalmol 2011:252549. 2011
    ..At this time, the data are not consistent and no definite conclusions may be drawn. As clinical trials data continue to accumulate, these relationships may become more apparent...
  34. pmc Risk factors for endophthalmitis and retinal detachment with retained intraocular foreign bodies
    D Wilkin Parke
    Department of Ophthalmology, Bascom Palmer Eye Institute, Miller School of Medicine, University of Miami, Miami, FL 33136, USA
    J Ophthalmol 2012:758526. 2012
    ..Risk factors for RD were posterior entry site, posterior segment IOFB, endophthalmitis, and retinal impact sites. No eyes developed endophthalmitis after presentation...
  35. doi request reprint Ocular complication of intense pulsed light therapy: iris photoablation
    Golnaz Javey
    Department of Ophthalmology, Baylor College of Medicine, Houston, Texas Department of Ophthalmology, Bascom Palmer Eye Institute, Miller School of Medicine, University of Miami, Miami, Florida
    Dermatol Surg 36:1466-8. 2010
    ..The authors have indicated no significant interest with commercial supporters...
  36. pmc Pars plana vitrectomy for primary rhegmatogenous retinal detachment
    Stephen G Schwartz
    Department of Ophthalmology, Bascom Palmer Eye Institute, University of Miami Miller School of Medicine, Miami, FL, USA
    Clin Ophthalmol 2:57-63. 2008
    ..At this time, the choice of SB versus PPV should be based on the characteristics of the RD, the patient as a whole, and the experience and preference of the individual retinal surgeon...
  37. ncbi request reprint Retained lens fragments in resident-performed cataract extractions
    Stephen G Schwartz
    Department of Ophthalmology, Medical College, Virginia Campus of Virginia Commonwealth University, Richmond, USA
    CLAO J 28:44-7. 2002
    ..To investigate the incidence, management, and outcome of retained lens fragments following resident-performed cataract extraction...