JANICE SCHWARTZ

Summary

Affiliation: University of California
Country: USA

Publications

  1. doi request reprint Effects of vitamin D supplementation in atorvastatin-treated patients: a new drug interaction with an unexpected consequence
    J B Schwartz
    Department of Research, The Jewish Home of San Francisco, San Francisco, California, USA
    Clin Pharmacol Ther 85:198-203. 2009
  2. pmc Patterns of chronic co-morbid medical conditions in older residents of U.S. nursing homes: differences between the sexes and across the agespan
    K L Moore
    J B Schwartz, MD, Research Department, 302 Silver Avenue, San Francisco, CA 94112 415 406 1573, fax 415 406 1577
    J Nutr Health Aging 18:429-36. 2014
  3. pmc Vitamin D3 effects on lipids differ in statin and non-statin-treated humans: superiority of free 25-OH D levels in detecting relationships
    Lynn Kane
    MD, 302 Silver Avenue, San Francisco, CA 94112
    J Clin Endocrinol Metab 98:4400-9. 2013
  4. ncbi request reprint Population analyses of atorvastatin clearance in patients living in the community and in nursing homes
    J B Schwartz
    Division of Clinical Pharmacology, University of California, San Francisco, San Francisco, California, USA
    Clin Pharmacol Ther 86:497-502. 2009
  5. doi request reprint Failure of pharmacogenetic-based dosing algorithms to identify older patients requiring low daily doses of warfarin
    Janice B Schwartz
    Jewish Home, San Francisco, CA, USA
    J Am Med Dir Assoc 12:633-8. 2011
  6. doi request reprint Effects of testosterone on the Q-T interval in older men and older women with chronic heart failure
    J B Schwartz
    Department of Medicine, University of California, San Francisco, CA 94112, USA
    Int J Androl 34:e415-21. 2011
  7. ncbi request reprint What does the Medicare prescription drug legislation mean for the American cardiologist?
    Janice B Schwartz
    Jewish Home of San Francisco and the Division of Clinical Pharmacology, University of California, San Francisco, CA 94112, USA
    Am J Geriatr Cardiol 14:317-24. 2005
  8. ncbi request reprint Gender-specific implications for cardiovascular medication use in the elderly optimizing therapy for older women
    Janice B Schwartz
    Divisions of Clinical Pharmacology and Cardiology, University of California, San Francisco and Jewish Home of San Francisco, San Francisco, CA 94112, USA
    Cardiol Rev 11:275-98. 2003
  9. ncbi request reprint The influence of sex on pharmacokinetics
    Janice B Schwartz
    Institute on Aging and Jewish Home of San Francisco, and University of California, San Francisco, California 94112, USA
    Clin Pharmacokinet 42:107-21. 2003
  10. ncbi request reprint Erythromycin breath test results in elderly, very elderly, and frail elderly persons
    Janice B Schwartz
    Jewish Home of San Francisco and Division of Clinical Pharmacology, Department of Medicine, University of California, San Francisco, California, USA
    Clin Pharmacol Ther 79:440-8. 2006

Research Grants

Collaborators

Detail Information

Publications17

  1. doi request reprint Effects of vitamin D supplementation in atorvastatin-treated patients: a new drug interaction with an unexpected consequence
    J B Schwartz
    Department of Research, The Jewish Home of San Francisco, San Francisco, California, USA
    Clin Pharmacol Ther 85:198-203. 2009
    ..005) were lower during vitamin D supplementation. The conclusion of the study is that vitamin D supplementation lowers atorvastatin and active metabolite concentrations yet has synergistic effects on cholesterol concentrations...
  2. pmc Patterns of chronic co-morbid medical conditions in older residents of U.S. nursing homes: differences between the sexes and across the agespan
    K L Moore
    J B Schwartz, MD, Research Department, 302 Silver Avenue, San Francisco, CA 94112 415 406 1573, fax 415 406 1577
    J Nutr Health Aging 18:429-36. 2014
    ..Our goal was to determine the most common co-morbid medical conditions in older residents of U.S. nursing homes and identify sex differences in prevalences and changes across the agespan of nursing residents...
  3. pmc Vitamin D3 effects on lipids differ in statin and non-statin-treated humans: superiority of free 25-OH D levels in detecting relationships
    Lynn Kane
    MD, 302 Silver Avenue, San Francisco, CA 94112
    J Clin Endocrinol Metab 98:4400-9. 2013
    ..Inverse associations between 25-OH vitamin D levels and cardiovascular morbidity and mortality have been reported...
  4. ncbi request reprint Population analyses of atorvastatin clearance in patients living in the community and in nursing homes
    J B Schwartz
    Division of Clinical Pharmacology, University of California, San Francisco, San Francisco, California, USA
    Clin Pharmacol Ther 86:497-502. 2009
    ....
  5. doi request reprint Failure of pharmacogenetic-based dosing algorithms to identify older patients requiring low daily doses of warfarin
    Janice B Schwartz
    Jewish Home, San Francisco, CA, USA
    J Am Med Dir Assoc 12:633-8. 2011
    ..We evaluated performance of pharmacogenetic-based warfarin dosing estimation algorithms in old and very old patients...
  6. doi request reprint Effects of testosterone on the Q-T interval in older men and older women with chronic heart failure
    J B Schwartz
    Department of Medicine, University of California, San Francisco, CA 94112, USA
    Int J Androl 34:e415-21. 2011
    ..Mean decreases are small and unlikely to affect risks of arrhythmic events in patients receiving Q-T prolonging medications...
  7. ncbi request reprint What does the Medicare prescription drug legislation mean for the American cardiologist?
    Janice B Schwartz
    Jewish Home of San Francisco and the Division of Clinical Pharmacology, University of California, San Francisco, CA 94112, USA
    Am J Geriatr Cardiol 14:317-24. 2005
    ..This article details the background, benefits, and expected impact of all of these aspects of the new Medicare Part D prescription drug benefit...
  8. ncbi request reprint Gender-specific implications for cardiovascular medication use in the elderly optimizing therapy for older women
    Janice B Schwartz
    Divisions of Clinical Pharmacology and Cardiology, University of California, San Francisco and Jewish Home of San Francisco, San Francisco, CA 94112, USA
    Cardiol Rev 11:275-98. 2003
    ..Optimal care for the older woman with cardiovascular disease will also require investigation of cardiovascular medications in older women and of therapies for cardiovascular diseases that are more common in women than men...
  9. ncbi request reprint The influence of sex on pharmacokinetics
    Janice B Schwartz
    Institute on Aging and Jewish Home of San Francisco, and University of California, San Francisco, California 94112, USA
    Clin Pharmacokinet 42:107-21. 2003
    ..The relative role of sex on pharmacokinetics as compared to genetics, age, disease, social habits and their potential interactions in the clinical setting is not yet fully known but should be routinely considered and further studied...
  10. ncbi request reprint Erythromycin breath test results in elderly, very elderly, and frail elderly persons
    Janice B Schwartz
    Jewish Home of San Francisco and Division of Clinical Pharmacology, Department of Medicine, University of California, San Francisco, California, USA
    Clin Pharmacol Ther 79:440-8. 2006
    ..Our objective was to determine the effects of very old age and frailty on erythromycin breath test (ERBT) results in patients and, secondarily, to determine the effects of sex and comedications on ERBT results...
  11. ncbi request reprint Sex differences in major bleeding with glycoprotein IIb/IIIa inhibitors: results from the CRUSADE (Can Rapid risk stratification of Unstable angina patients Suppress ADverse outcomes with Early implementation of the ACC/AHA guidelines) initiative
    Karen P Alexander
    Duke Clinical Research Institute, Duke University Medical Center, Durham, NC 27715, USA
    Circulation 114:1380-7. 2006
    ..The contribution of dosing to the observed sex-related differences in bleeding is unknown...
  12. ncbi request reprint Population analyses of amlodipine in patients living in the community and patients living in nursing homes
    Dongwoo Kang
    Department of Medicine, Division of Clinical Pharmacology, University of California, San Francisco, Calif, USA
    Clin Pharmacol Ther 79:114-24. 2006
    ..Our objective was to determine the effects of age, sex, and morbidity on the apparent oral clearance (CL/F) of amlodipine...
  13. ncbi request reprint Sample size computations for PK/PD population models
    Dongwoo Kang
    Department of Biopharmaceutical Sciences, University of California at San Francisco, 521 Parnassus Avenue, Box 0446, San Francisco, CA 94143 0446, USA
    J Pharmacokinet Pharmacodyn 32:685-701. 2005
    ..The method is general and can accommodate any type of hierarchical models. Simulation results suggest that intensive sampling allows the reduction of the number of patients enrolled in a clinical study...
  14. ncbi request reprint A sample size computation method for non-linear mixed effects models with applications to pharmacokinetics models
    Dongwoo Kang
    Department of Biopharmaceutical Sciences, University of California San Francisco, San Francisco, CA 94132 0446, USA
    Stat Med 23:2551-66. 2004
    ..The proposed method greatly reduces computing times compared with simulation-based methods of estimating sample sizes for population PK studies...
  15. ncbi request reprint Sudden cardiac death among women in the United States
    Janice B Schwartz
    Circulation 108:e153; author reply e153. 2003
  16. ncbi request reprint Population analyses of sustained-release verapamil in patients: effects of sex, race, and smoking
    Dongwoo Kang
    Division of Clinical Pharmacology, Department of Biopharmaceutical Sciences, University of California at San Francisco, San Francisco, USA
    Clin Pharmacol Ther 73:31-40. 2003
    ..Our objective was to determine the effects of age, sex, and sustained-release formulation on apparent oral clearance of sustained-release racemic verapamil in patient populations...
  17. ncbi request reprint Pharmacogenetics: has it reached the clinic?
    Janice B Schwartz
    Long Term Care Research Center, Institute on Aging Jewish Home, 302 Silver Ave, San Francisco, CA 94112, USA
    J Gend Specif Med 5:13-8. 2002
    ..g., 6-mercaptopurine and azathioprine) because clinically life-threatening complications or decreased efficacy is strongly related to the genetically determined activity of this enzyme...

Research Grants10

  1. OLDER PERSONS AND DRUGS--RACE, GENDER, AND AGE EFFECTS
    JANICE SCHWARTZ; Fiscal Year: 2000
    ..Further studies are planned to compare oral pharmacokinetics of verapamil and/ nifedipine in similar subjects on a standardized diet. ..
  2. Older Persons & Drugs: race, gender, and age effects
    JANICE SCHWARTZ; Fiscal Year: 2009
    ..The potential impact of these findings on the care of the growing number of very old patients, especially understudied women and minority groups, is great. ..
  3. Older Persons & Drugs: race, gender, and age effects
    JANICE SCHWARTZ; Fiscal Year: 2007
    ..The potential impact of these findings on the care of the growing number of very old patients, especially understudied women and minority groups, is great. ..
  4. Older Persons & Drugs: race, gender, and age effects
    JANICE SCHWARTZ; Fiscal Year: 2006
    ..The potential impact of these findings on the care of the growing number of very old patients, especially understudied women and minority groups, is great. ..
  5. Older Persons & Drugs: race, gender, and age effects
    JANICE SCHWARTZ; Fiscal Year: 2005
    ..The potential impact of these findings on the care of the growing number of very old patients, especially understudied women and minority groups, is great. ..
  6. OLDER PERSONS AND DRUGS--RACE, GENDER, AND AGE EFFECTS
    JANICE SCHWARTZ; Fiscal Year: 2003
    ..Further studies are planned to compare oral pharmacokinetics of verapamil and/ nifedipine in similar subjects on a standardized diet. ..
  7. OLDER PERSONS AND DRUGS--RACE, GENDER, AND AGE EFFECTS
    JANICE SCHWARTZ; Fiscal Year: 2002
    ..Further studies are planned to compare oral pharmacokinetics of verapamil and/ nifedipine in similar subjects on a standardized diet. ..
  8. OLDER PERSONS AND DRUGS--RACE, GENDER, AND AGE EFFECTS
    JANICE SCHWARTZ; Fiscal Year: 2001
    ..Further studies are planned to compare oral pharmacokinetics of verapamil and/ nifedipine in similar subjects on a standardized diet. ..
  9. Older Persons & Drugs: race, gender, and age effects
    JANICE SCHWARTZ; Fiscal Year: 2009
    ..The potential impact of these findings on the care of the growing number of very old patients, especially understudied women and minority groups, is great. ..