STEPHAN C SCHURER

Summary

Affiliation: University of Miami
Country: USA

Publications

  1. pmc Kinome-wide activity modeling from diverse public high-quality data sets
    STEPHAN C SCHURER
    Department of Molecular and Cellular Pharmacology, Miller School of Medicine and Center for Computational Science, University of Miami, Miami, Florida 33136, USA
    J Chem Inf Model 53:27-38. 2013
  2. pmc BioAssay ontology annotations facilitate cross-analysis of diverse high-throughput screening data sets
    STEPHAN C SCHURER
    Center for Computational Science, University of Miami, Miami, Florida 33136, USA
    J Biomol Screen 16:415-26. 2011
  3. pmc Formalization, annotation and analysis of diverse drug and probe screening assay datasets using the BioAssay Ontology (BAO)
    Uma D Vempati
    Center for Computational Science, University of Miami, Miami, Florida, United States of America
    PLoS ONE 7:e49198. 2012
  4. pmc Chemical interrogation of the neuronal kinome using a primary cell-based screening assay
    Hassan Al-Ali
    Miami Project to Cure Paralysis, University of Miami Miller School of Medicine, Miami, FL 33136, USA
    ACS Chem Biol 8:1027-36. 2013
  5. pmc GPCR ontology: development and application of a G protein-coupled receptor pharmacology knowledge framework
    Magdalena J Przydzial
    Center for Computational Science, University of Miami, Miami, FL 33136, USA and Department of Molecular and Cellular Pharmacology, Miller School of Medicine, University of Miami, Miami, FL 33136, USA
    Bioinformatics 29:3211-9. 2013
  6. doi request reprint Novel kinase inhibitors by reshuffling ligand functionalities across the human kinome
    Dušica Vidović
    Center for Computational Science, Miller School of Medicine, University of Miami, Miami, Florida 33136, USA
    J Chem Inf Model 52:3107-15. 2012
  7. pmc BioAssay Ontology (BAO): a semantic description of bioassays and high-throughput screening results
    Ubbo Visser
    Department of Computer Science, University of Miami, Coral Gables, FL, USA
    BMC Bioinformatics 12:257. 2011

Collaborators

  • Magdalena J Przydzial
  • Ubbo Visser
  • Hassan Al-Ali
  • Vance P Lemmon
  • Uma Vempati
  • Dušica Vidović
  • Uma D Vempati
  • Saminda Abeyruwan
  • Barun Bhhatarai
  • Amar Koleti
  • John L Bixby
  • Steven M Muskal
  • Kunie Sakurai
  • Caty Chung
  • Ahsan Mir
  • Vance Lemmon
  • Robin P Smith

Detail Information

Publications7

  1. pmc Kinome-wide activity modeling from diverse public high-quality data sets
    STEPHAN C SCHURER
    Department of Molecular and Cellular Pharmacology, Miller School of Medicine and Center for Computational Science, University of Miami, Miami, Florida 33136, USA
    J Chem Inf Model 53:27-38. 2013
    ....
  2. pmc BioAssay ontology annotations facilitate cross-analysis of diverse high-throughput screening data sets
    STEPHAN C SCHURER
    Center for Computational Science, University of Miami, Miami, Florida 33136, USA
    J Biomol Screen 16:415-26. 2011
    ..Furthermore, they show that BAO is a valuable toolset for the identification of related assays and for the systematic generation of insights that are beyond the scope of individual assays or screening campaigns...
  3. pmc Formalization, annotation and analysis of diverse drug and probe screening assay datasets using the BioAssay Ontology (BAO)
    Uma D Vempati
    Center for Computational Science, University of Miami, Miami, Florida, United States of America
    PLoS ONE 7:e49198. 2012
    ..As a consequence, BAO offers the potential to infer new knowledge from a corpus of assay results, for example molecular mechanisms of action of perturbagens...
  4. pmc Chemical interrogation of the neuronal kinome using a primary cell-based screening assay
    Hassan Al-Ali
    Miami Project to Cure Paralysis, University of Miami Miller School of Medicine, Miami, FL 33136, USA
    ACS Chem Biol 8:1027-36. 2013
    ..This study can serve as a jumping-off point for structure activity relationship (SAR) and other drug discovery approaches toward the development of drugs for treating SCI and related neurological pathologies...
  5. pmc GPCR ontology: development and application of a G protein-coupled receptor pharmacology knowledge framework
    Magdalena J Przydzial
    Center for Computational Science, University of Miami, Miami, FL 33136, USA and Department of Molecular and Cellular Pharmacology, Miller School of Medicine, University of Miami, Miami, FL 33136, USA
    Bioinformatics 29:3211-9. 2013
    ..As the largest class of drug targets, G protein-coupled receptors (GPCRs) remain of particular interest and are pursued by numerous academic and industrial research projects...
  6. doi request reprint Novel kinase inhibitors by reshuffling ligand functionalities across the human kinome
    Dušica Vidović
    Center for Computational Science, Miller School of Medicine, University of Miami, Miami, Florida 33136, USA
    J Chem Inf Model 52:3107-15. 2012
    ..Here, we systematize and automate this approach leveraging available knowledge covering the entire human Kinome...
  7. pmc BioAssay Ontology (BAO): a semantic description of bioassays and high-throughput screening results
    Ubbo Visser
    Department of Computer Science, University of Miami, Coral Gables, FL, USA
    BMC Bioinformatics 12:257. 2011
    ..Novel approaches to organize, standardize and access HTS data are required to address these challenges...