S K Schultz
Affiliation: University of Iowa
- Alcohol use and health outcomes in the oldest oldCarolyn L Turvey
Department of Psychiatry, University of Iowa, Iowa City, IA, USA
Subst Abuse Treat Prev Policy 1:8. 2006..Public health recommendations for moderate drinking must take this phenomenon into account...
- Alcohol use among older persons in a rural stateSusan K Schultz
Dept of Psychiatry, University of Iowa College of Medicine, Iowa City 52242, USA
Am J Geriatr Psychiatry 10:750-3. 2002..Older individuals are vulnerable to adverse consequences from alcoholism; unfortunately, alcohol-related problems are often under-identified in this group...
- Evaluation of older persons with mild cognitive deficits: potential utility of magnetic resonance imagingSusan K Schultz
University of Iowa Department of Psychiatry, Carver College of Medicine, Iowa City, IA 52242 1000, USA
Ann Clin Psychiatry 20:204-8. 2008..The objective was to examine cortical volumes in relation to cognitive performance among patients who do not have dementia, but who do have mild cognitive deficits...
- Age and regional cerebral blood flow in schizophrenia: age effects in anterior cingulate, frontal, and parietal cortexSusan K Schultz
Department of Radiology, University of Iowa College of Medicine, Iowa City, Iowa 52242 1000, USA
J Neuropsychiatry Clin Neurosci 14:19-24. 2002..In contrast, the reduced flow observed in the frontal and parietal regions may be unique to schizophrenia...
- Heart rate variability before and after treatment with electroconvulsive therapyS K Schultz
Department of Psychiatry, University of Iowa, College of Medicine, Iowa City, IA 2242, USA
J Affect Disord 44:13-20. 1997..Further work is necessary to better understand the autonomic changes associated with depressive illness and the clinical risks and benefits associated with various treatment modalities...
- Clinical features characterizing young-onset and intermediate-onset schizophreniaS K Schultz
University of Iowa, Department of Psychiatry, Mental Health Clinical Research Center, Iowa City, USA
J Neuropsychiatry Clin Neurosci 12:502-5. 2000..The dichotomy of early vs. late onset may extend to a younger population, reflecting a more continuous influence...
- SchizophreniaS K Schultz
Mental Health Clinical Research Center, Department of Psychiatry, University of Iowa, Iowa City 52242, USA
Lancet 353:1425-30. 1999..Despite these advances, treatment of symptoms and psychosocial and cognitive impairments remains only partially successful for many patients...
- Donepezil effects on cerebral blood flow in older adults with mild cognitive deficitsXiying Chen
Department of Radiology, The Roy J and Lucille A Carver College of Medicine, 500 Newton Rd, Iowa City, IA 52242 1000, USA
J Neuropsychiatry Clin Neurosci 18:178-85. 2006..These findings suggest that donepezil treatment may be associated with a relative maintenance of CBF and improved list-learning...
- The influence of cognitive impairment and psychiatric symptoms on daily functioning in nursing facilities: a longitudinal studySusan K Schultz
Department of Psychiatry, University of Iowa College of Medicine, 500 Newton Road, Iowa City, Iowa 52242 1000, USA
Ann Clin Psychiatry 14:209-13. 2002..These findings may have implications for treatment interventions that seek to enhance functioning in the skilled nursing setting...
- Managing perplexing patients: the case of HelenMarianne Smith
University of Iowa, Iowa City, Iowa, USA
Issues Ment Health Nurs 26:47-63. 2005..Linked nursing diagnoses, outcomes and interventions, and interdisciplinary care plans emphasize the changing care needs of such patients...
- Association between cytochrome P4502D6 (CYP2D6) genotype, antipsychotic exposure, and abnormal involuntary movement scale (AIMS) scoreV L Ellingrod
College of Pharmacy, University of Iowa, Iowa City, USA
Psychiatr Genet 10:9-11. 2000..044) compared with (*1/*3 or *4) patients (slope = 0.001). These results suggest patients with a *3 or *4 allele may have a higher risk for developing antipsychotic induced abnormal movements...
- Social environment and longevity in schizophreniaA J Christensen
Department of Psychology, The University of Iowa, Iowa City 52242, USA
Psychosom Med 61:141-5. 1999..The role of social support as a predictor of long-term survival among patients with schizophrenia was examined...
- Quantitative in vivo measurement of gyrification in the human brain: changes associated with agingV A Magnotta
Mental Health Clinical Research Center, The University of Iowa College of Medicine and Hospitals and Clinics, Iowa City 52242, USA
Cereb Cortex 9:151-60. 1999..Measurements of sulcal and gyral shape may be useful in studying the mechanisms of both neurodevelopmental and neurodegenerative changes that occur during brain maturation and aging...
- Unilateral vs. bilateral ultrasound in the monitoring of cerebral microemboliD J Moser
Department of Psychiatry, University of Iowa, Iowa City, IA 52240, USA
Ultrasound Med Biol 27:757-60. 2001..However, when precise ME counts are required, bilateral monitoring is essential...
- Global cerebral blood flow in relation to cognitive performance and reserve in subjects with mild memory deficitsLaura L Boles Ponto
Positron Emission Tomography Imaging Center, Department of Radiology, Roy J and Lucille A Carver College of Medicine, University of Iowa, Iowa, IA 52242, USA
Mol Imaging Biol 8:363-72. 2006..This study was undertaken to explore the mechanisms underlying cognitive reserve in subjects with mild memory deficits by using positron emission tomography (PET)...
- Basal metabolic rate in anorexia nervosa patients: using appropriate predictive equations during the refeeding processValerie L Forman-Hoffman
Department of Respiratory Care, The University of Iowa, Roy J and Lucille A Carver College of Medicine, Iowa City, IA, USA
Ann Clin Psychiatry 18:123-7. 2006..Accurate predictive equations of basal metabolic rate (BMR) are needed to ensure AN patients gain weight at a safe rate...
- Ginkgo biloba extract: review of CNS effectsLaura L Boles Ponto
Department of Radiology, Positron Emission Tomography Imaging Center, Roy J and Lucille A Carver College of Medicine, University of Iowa, Iowa City, Iowa 52242, USA
Ann Clin Psychiatry 15:109-19. 2003..Limitations of the current scientific literature are highlighted and suggestions for future human and animal research directions are proposed...
- Practice effects in the prediction of long-term cognitive outcome in three patient samples: a novel prognostic indexKevin Duff
University of Iowa, Department of Psychiatry, MEB 1 308, Iowa City, IA 52242 1000, United States
Arch Clin Neuropsychol 22:15-24. 2007..Additionally, this prognostic index could be used to offer interventions to patients who are in the earliest stages of progressive neurodegenerative disorders...
- Effects of smoking marijuana on focal attention and brain blood flowDANIEL S O'LEARY
Department of Psychiatry, Roy J and Lucille A Carver College of Medicine, The University of Iowa, Iowa 52242, USA
Hum Psychopharmacol 22:135-48. 2007..These data indicate that marijuana has dramatic direct effects on rCBF, but causes relatively little change in the normal pattern of task-related rCBF on this auditory focused attention task...
- Dementia, goals of care, and personhood: a study of surrogate decision makers' beliefs and valuesLauris C Kaldjian
Division of General Internal Medicine, Department of Internal Medicine, University of Iowa Carver College of Medicine, Iowa City, IA 52242, USA
Am J Hosp Palliat Care 27:387-97. 2010..In conclusion, the surrogates we interviewed expressed diverse preferences regarding goals of care and diverse assessments about the impact of dementia on personhood...
- Short-term practice effects in amnestic mild cognitive impairment: implications for diagnosis and treatmentKevin Duff
Department of Psychiatry, College of Medicine, University of Iowa, Iowa City, IA 52242 1000, USA
Int Psychogeriatr 20:986-99. 2008..Practice effects have been widely reported in healthy older adults, but these improvements due to repeat exposure to test materials have been more equivocal in individuals with mild cognitive impairment (MCI)...
- Dementia care in assisted living: needs and challengesMarianne Smith
University of Iowa, College of Nursing, Iowa City, Iowa 52242, USA
Issues Ment Health Nurs 29:817-38. 2008....
- Tales from the field: what the nursing research textbooks will not tell youMarianne Smith
University of Iowa College of Nursing, Iowa City, IA 52242, USA
Appl Nurs Res 21:232-6. 2008..Lessons learned, which are believed to be valuable to both neophyte and seasoned researchers, are reviewed...
- A longitudinal community-based study of chronic illness, cognitive and physical function, and depressionCarolyn L Turvey
Department of Psychiatry, University of Iowa, 500 Newton Road, Iowa City, IA 52242 1000, USA
Am J Geriatr Psychiatry 17:632-41. 2009..This study examines the relative contribution of cognitive function, physical function, and chronic illness to depression 2 years later in a nationwide sample of elders aged 70 and older...
- Anxiety, depression, and cognitive impairment in dementia-specific and traditional assisted livingHyunwook Kang
The University of Iowa College of Nursing, Iowa City, Iowa 52242, USA
J Gerontol Nurs 36:18-30; quiz 32-3. 2010..No statistically significant differences in demographic factors or levels of anxiety or depression were observed among residents in either setting...
- Neuropsychological outcomes of older breast cancer survivors: cognitive features ten or more years after chemotherapyTorricia H Yamada
Department of Neurology, University of Iowa Carver College of Medicine, USA
J Neuropsychiatry Clin Neurosci 22:48-54. 2010..Our findings suggest that among breast cancer survivors who remain disease-free for more than a decade, the previous cancer treatment may further augment cognitive dysfunction associated with age-related brain changes...
- Using a brief intervention to improve decisional capacity in schizophrenia researchDavid J Moser
Department of Psychiatry MEB 1 328, University of Iowa Carver College of Medicine, Iowa City, IA 52242, USA
Schizophr Bull 32:116-20. 2006..The use of such interventions will enable a larger number of people with schizophrenia to make informed decisions regarding research participation...
- Capacity to provide informed consent for participation in schizophrenia and HIV researchDavid J Moser
Department of Psychiatry, Mental Health Clinical Research Center, University of Iowa College of Medicine, 200 Hawkins Drive, Iowa City, IA 52240, USA
Am J Psychiatry 159:1201-7. 2002....
- Screening for alcoholism in the primary care setting: are we talking to the right people?Stephan Arndt
University of Iowa College of Medicine, Psychiatry Research MEB, Iowa City, IO 52242, USA
J Fam Pract 51:41-6. 2002..This study assessed which demographic groups were most likely to consume alcohol excessively, and which groups had received inquiries and discussion about alcohol use from their physicians compared with discussions about other health risks...
- Abnormal movements and tardive dyskinesia in smokers and nonsmokers with schizophrenia genotyped for cytochrome P450 2D6Vicki L Ellingrod
College of Pharmacy, University of Iowa, Iowa City 52242, USA
Pharmacotherapy 22:1416-9. 2002..To investigate the relationships between cytochrome P450 (CYP) 2D6 genotype, antipsychotic drug exposure, abnormal movements and tardive dyskinesia, and cigarette smoking...
- CYP2D6 polymorphisms and atypical antipsychotic weight gainVicki L Ellingrod
College of Pharmacy, University of Iowa, Iowa City, Iowa, USA
Psychiatr Genet 12:55-8. 2002..This may be due to increased olanzapine concentrations leading to increased exposure, which may trigger AAP weight gain...
- The influence of cognitive impairment and behavioral dysregulation on daily functioning in the nursing home settingSusan K Schultz
Department of Psychiatry, University of Iowa College of Medicine, Iowa City, 52242 1000, USA
Am J Psychiatry 160:582-4. 2003..The influence of psychiatric symptoms and cognitive impairment on daily living skills was explored in a series of nursing home residents. Three categories of symptoms were examined: behavioral disturbances, depression, and delusions...
- Technical issues in the determination of cerebrovascular reserve in elderly subjects using 15O-water PET imagingLaura L Boles Ponto
Positron Emission Tomography Imaging Center, Department of Radiology, Roy J and Lucille A Carver College of Medicine, University of Iowa Hospitals and Clinics, Iowa City, IA 52242, USA
Neuroimage 21:201-10. 2004..g., heart rate, blood pressure, level of anxiety) of the patient...
- Anxiety and impaired social function in the elderlySusan K Schultz
Psychiatry Research, University of Iowa College of Medicine, Iowa City, Iowa 52242 1000, USA
Ann Clin Psychiatry 16:47-51. 2004..Current interventions for anxiety such as benzodiazepines may have adverse cognitive effects, hence more specific intervention strategies for anxiety may be very important for this population...
- Blood vessel function and cognition in elderly patients with atherosclerosisDavid J Moser
Department of Psychiatry, MEB 1 328, University of Iowa Carver College of Medicine, Iowa City, IA 52242 1000, USA
Stroke 35:e369-72. 2004..This study was conducted to determine the relationship between blood vessel function and cognition in elderly patients with atherosclerosis...
- Comparison of risperidone with olanzapine in elderly patients with dementia and psychosisVicki L Ellingrod
College of Pharmacy, University of Iowa, Iowa City, USA
Pharmacotherapy 22:1-5. 2002..To compare the effects of risperidone and olanzapine on cognition in elderly patients with dementia and psychosis, and to compare the side effects of these drugs...
- Informed consent in medication-free schizophrenia researchDavid J Moser
Department of Psychiatry, University of Iowa, Carver College of Medicine, Iowa City, IA 52242, USA
Am J Psychiatry 162:1209-11. 2005..The authors' goal was to determine whether people with schizophrenia experience changes in decisional capacity when their antipsychotic regimens are discontinued for research purposes...
- Effects of smoking marijuana on brain perfusion and cognitionDANIEL S O'LEARY
Mental Health Clinical Research Center, University of Iowa College of Medicine, Iowa City, IA 52242 1057, USA
Neuropsychopharmacology 26:802-16. 2002..There was no significant rCBF change in the nucleus accumbens or other reward-related brain regions, nor in basal ganglia or hippocampus, which have a high density of cannabinoid receptors...
- Nortriptyline versus fluoxetine in the treatment of depression and in short-term recovery after stroke: a placebo-controlled, double-blind studyR G Robinson
Department of Psychiatry, University of Iowa, Iowa City 52242, USA
Am J Psychiatry 157:351-9. 2000..This study compared nortriptyline and fluoxetine with placebo in the treatment of depression and in recovery from physical and cognitive impairments after stroke...
- Elderly patients with dementia-related symptoms of severe agitation and aggression: consensus statement on treatment options, clinical trials methodology, and policyCarl Salzman
Department of Psychiatry, Harvard Medical School, Boston, Mass 02115, USA
J Clin Psychiatry 69:889-98. 2008..In 2005, the FDA issued a black box warning regarding increased risk of mortality associated with the use of atypical antipsychotic drugs in this patient population...
- Caregiver report of hallucinations and paranoid delusions in elders aged 70 or olderC L Turvey
Department of Psychiatry University of Iowa, Iowa City, 52242 1000, USA
Int Psychogeriatr 13:241-9. 2001..Depressive symptoms and stroke were associated with hallucinations only. These results suggest that inadequate external stimulation in the elderly leads to psychotic experiences...
- Locations of facilities with special programs for older substance abuse clients in the USSusan K Schultz
Department of Psychiatry, College of Medicine, University of Iowa, Iowa City, IA 52242, USA
Int J Geriatr Psychiatry 18:839-43. 2003..Given the growth of our aging population, developing strategies for managing late-life alcoholism is increasingly important...
- Late-life depression: a model for medical classificationGeorge S Alexopoulos
Weill Medical College of Cornell University, White Plains, New York 10605, USA
Biol Psychiatry 58:283-9. 2005....
- Depression in the older adult: the challenge of medical comorbiditySusan K Schultz
Am J Psychiatry 164:847-8. 2007
- Potential ethnic modifiers in the assessment and treatment of Alzheimer's disease: challenges for the futureWarachal E Faison
Alzheimer s Research and Clinical Programs, Neurosciences Department, Medical University of South Carolina, Charleston, South Carolina 29406, USA
Int Psychogeriatr 19:539-58. 2007..for AD to answer two questions: (1) what are the challenges to diagnose and treat AD across different ethnic groups, and (2) are there differences in response to pharmacologic interventions for AD across these different ethnic groups?..
- Phobic anxiety in late-life in relationship to cognition and 5HTTLPR polymorphismSusan K Schultz
Psychiatr Genet 15:305-6. 2005..However, in this sample we did not detect a significant association between phobic anxiety and the 5HTTLPR genotype. The interaction between age-related changes in cognition and anxiety remain an important area for future studies...
- The neuropsychiatry of agingSusan K Schultz
Am J Psychiatry 162:1993-5. 2005
- Long-term adjunctive quetiapine may reduce substance use--a preliminary retrospective studyS Pirzada Sattar
Avera McKennan Research Institute, Sioux Falls, SD, USA
S D Med 60:437, 439-41, 443 passim. 2007..However, there are no reports of long-term benefits of these medications...
- Atypical antipsychotic medications in Alzheimer's disease: effectiveness versus expectationsSusan K Schultz
Am J Psychiatry 165:787-9. 2008
- LA allelic heterozygosity of the 5HTTLPR polymorphism is associated with higher cognitive function and lower interpersonal sensitivityJess G Fiedorowicz
Psychiatr Genet 17:3-4. 2007
- Serotonin 2A -1438 G/A and G-protein Beta3 subunit C825T polymorphisms in patients with depression and SSRI-associated sexual side-effectsJeffrey R Bishop
University of Illinois at Chicago College of Pharmacy, Chicago, IL, USA
Neuropsychopharmacology 31:2281-8. 2006..6; p=0.046). Furthermore, the 5HT2A -1438 GG genotype was a significant predictor of lower arousal scores (p=0.022) after accounting for other measures. There was no significant relationship between any outcome measure and GNB3 genotype...
- Biomarkers in psychiatry: methodological issuesHelena Chmura Kraemer
Department of Psychiatry and Behavioral Sciences, Stanford University, CA 94305, USA
Am J Geriatr Psychiatry 10:653-9. 2002..Authors discuss methods for establishing the validity of a biomarker. Finally, they convey a word of caution about overinterpreting the clinical or scientific value of any biological measure...