Affiliation: University of California
- Membrane expansion alleviates endoplasmic reticulum stress independently of the unfolded protein responseSebastian Schuck
Howard Hughes Medical Institute and Department of Biochemistry and Biophysics, University of California, San Francisco, San Francisco, CA 94158, USA
J Cell Biol 187:525-36. 2009..Thus, increasing ER size through membrane synthesis is an integral yet distinct part of the cellular program to overcome ER stress...
- Homeostatic adaptation to endoplasmic reticulum stress depends on Ire1 kinase activityClaudia Rubio
Howard Hughes Medical Institute, San Francisco, CA, USA
J Cell Biol 193:171-84. 2011..Thus, Ire1-catalyzed phosphoryl-transfer aids disassembly of Ire1 signaling complexes and is a critical component of the UPR homeostatic feedback loop...
- Seg1 controls eisosome assembly and shapeKaren E Moreira
Howard Hughes Medical Institute and Department of Biochemistry and Biophysics, University of California San Francisco, San Francisco, CA 94158, USA
J Cell Biol 198:405-20. 2012..The function of Seg1 in the stepwise biogenesis of eisosomes reveals striking architectural similarities between eisosomes in yeast and caveolae in mammals...
- ER-phagy: selective autophagy of the endoplasmic reticulumSebastián Bernales
Howard Hughes Medical Institute, Department of Biochemistry, School of Medicine, University of California San Francisco, San Francisco, California 94158 2517, USA
Autophagy 3:285-7. 2007..ER-phagy could remove damaged or redundant parts of the ER and thus represent an important degradative functionality of the UPR that helps to afford homeostatic control...