Research Topics
Genomes and GenesSpecies | N F SchorSummaryAffiliation: University of Pittsburgh Country: USA Publications
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Detail Information
Publications
Selective oxidation and externalization of membrane phosphatidylserine: Bcl-2-induced potentiation of the final common pathway for apoptosisN F Schor
Department of Neurology, University of Pittsburgh, Pittsburgh, PA, USA
Brain Res 831:125-30. 1999..The mechanism of potentiation of apoptosis by Bcl-2 is related to the enhanced reducing potential of bcl-2-overexpressing PC12 cells...
Interrater concordance for faculty grading of student performances in a problem-based learning courseN F Schor
Department of Pediatrics, University of Pittsburgh School of Medicine, Pennsylvania, USA
Acad Med 72:150-1. 1997..To determine whether it is possible for faculty to arrive at consistent, non-idiosyncratic grades in a problem-based learning (PBL) course...
Neuroblastoma as a neurobiological diseaseN F Schor
Department of Pediatrics, University of Pittsburgh, PA 15213, USA
J Neurooncol 41:159-66. 1999..A neuroscientist's approach to neuroblastoma, its biology and clinical features, is presented herein...
Mechanisms of synergistic toxicity of the radioprotective agent, WR2721, and 6-hydroxydopamineN F Schor
Department of Pediatrics, Children s Hospital, University of Pittsburgh, PA 15213
Biochem Pharmacol 37:1751-62. 1988..Oxygen radicals not only inactivated the synthetase, as well, but hastened the oxidation of the free thiol metabolite of WR2721 to its corresponding disulfide...
Apoptosis in the absence of caspase 3Y Liang
Pediatric Center for Neuroscience, Children's Hospital of Pittsburgh, 3460 Fifth Avenue, Pittsburgh, PA 15213, USA
Oncogene 20:6570-8. 2001..P21 is detected only after activation of caspase 7, and P53 is neither expressed at baseline nor up-regulated with apoptosis induction. This pathway bypasses the need for activated caspase 3 in these cells...
Oxidative signaling pathway for externalization of plasma membrane phosphatidylserine during apoptosisV E Kagan
Department of Environmental and Occupational Health, University of Pittsburgh, 260 Kappa Drive, Pittsburgh, PA 15238, USA
FEBS Lett 477:1-7. 2000..Thus, cytochrome c-mediated phosphatidylserine oxidation may represent an important component of the apoptotic pathway...
Phosphatidylserine peroxidation during apoptosis. A signaling pathway for phagocyte clearanceY Y Tyurina
Department of Environmental and Occupational Health, University of Pittsburgh, Pennsylvania 15238, USA
Subcell Biochem 36:79-96. 2002
Inactivation of mammalian brain glutamine synthetase by oxygen radicalsN F Schor
Department of Pediatrics, Children s Hospital of Pittsburgh, PA 15213
Brain Res 456:17-21. 1988....
Exploiting oxidative stress and signaling in chemotherapy of resistant neoplasmsN F Schor
Department of Pediatrics, University of Pittsburgh, Pittsburgh, USA
Biochemistry (Mosc) 69:38-44. 2004....
Early events in Bcl-2-enhanced apoptosisY Liang
Pediatric Center for Neuroscience and Division of Child Neurology, Department of Pediatrics, University of Pittsburgh, Pittsburgh, PA 15213, USA
Apoptosis 8:609-16. 2003..This makes it unlikely that cleavage of Bcl-2 is the only factor involved in potentiation of NCS-induced apoptosis by Bcl-2...
Neuroblastoma: a neurochemical approachN F Schor
Department of Pediatrics, Children s Hospital of Pittsburgh, PA 15213
J Child Neurol 6:220-8. 1991..It is hoped that these strategies will be generalizable to other neural crest-derived tumors...
Interaction between 6-hydroxydopamine and transferrin: "Let my iron go"G G Borisenko
Department of Environmental and Occupational Health, University of Pittsburgh, Pittsburgh, Pennsylvania 15238, USA
Biochemistry 39:3392-400. 2000..These findings underscore the physiological and pharmacological relevance of 6-OHDA-mediated iron release from Fe-TF and suggest that iron chelators (DFO) may be used for prevention of 6-OHDA toxicity...
DNA microarray profiling of developing PS1-deficient mouse brain reveals complex and coregulated expression changesZ K Mirnics
Department of Pediatrics and Neurology, University of Pittsburgh, School of Medicine, Children s Hospital of Pittsburgh, Pittsburgh, PA 15213, USA
Mol Psychiatry 8:863-78. 2003....
