R S Schofield

Summary

Affiliation: University of Florida
Country: USA

Publications

  1. ncbi Cardiac transplantation in a patient with hereditary hemochromatosis: role of adjunctive phlebotomy and erythropoietin
    R S Schofield
    Division of Cardiology and Cardiac Transplantation, University of Florida College of Medicine, Gainesville, Florida, USA
    J Heart Lung Transplant 20:696-8. 2001
  2. ncbi Early outcomes of a care coordination-enhanced telehome care program for elderly veterans with chronic heart failure
    Richard S Schofield
    Cardiology Section, Rehabilitation Outcomes Research Center, Department of Veterans Affairs Medical Center, Gainesville, Florida, USA
    Telemed J E Health 11:20-7. 2005
  3. ncbi Left ventricular dysfunction after pericardiectomy for constrictive pericarditis
    Richard S Schofield
    Malcom Randall Veterans Administration Medical Center, Department of Medicine, University of Florida College of Medicine, Gainesville, USA
    Ann Thorac Surg 77:1449-51. 2004
  4. ncbi Role of metabolically active drugs in the management of ischemic heart disease
    R S Schofield
    Division of Cardiovascular Medicine, University of Florida College of Medicine, Gainesville, Florida 32610, USA
    Am J Cardiovasc Drugs 1:23-35. 2001
  5. ncbi Cardiac transplantation in patients with anti-phospholipid antibodies
    Richard S Schofield
    Department of Veterans Affairs Medical Center, Gainesville, Florida, USA
    J Heart Lung Transplant 26:299-301. 2007
  6. ncbi Vascular effects of sildenafil in hypertensive cardiac transplant recipients
    Richard S Schofield
    Division of Cardiovascular Medicine and Shands Transplant Center, University of Florida College of Medicine, Gainesville, Florida 32610, USA
    Am J Hypertens 16:874-7. 2003
  7. ncbi Hyperhomocysteinemia in patients with heart failure referred for cardiac transplantation: preliminary observations
    Richard S Schofield
    Division of Cardiovascular Medicine and Shands Transplant Center, University of Florida College of Medicine, Gainesville, Florida, USA
    Clin Cardiol 26:407-10. 2003
  8. ncbi Arterial-wave reflections are increased in heart failure patients with a left-ventricular assist device
    Richard S Schofield
    Department of Veterans Affairs Medical Center, Gainesville, Florida, USA
    Am J Hypertens 20:622-8. 2007
  9. ncbi Amplitude and timing of central aortic pressure wave reflections in heart transplant recipients
    Richard S Schofield
    Division of Cardiovascular Medicine and Shands Transplant Center, University of Florida, College of Medicine, Gainesville, USA
    Am J Hypertens 15:809-15. 2002
  10. ncbi Hormone therapy in men and risk of cardiac allograft rejection
    Richard S Schofield
    Division of Cardiovascular Medicine and University of Florida, Shands Transplant Center, University of Florida College of Medicine, Gainesville, Florida 32610, USA
    J Heart Lung Transplant 21:493-5. 2002

Detail Information

Publications50

  1. ncbi Cardiac transplantation in a patient with hereditary hemochromatosis: role of adjunctive phlebotomy and erythropoietin
    R S Schofield
    Division of Cardiology and Cardiac Transplantation, University of Florida College of Medicine, Gainesville, Florida, USA
    J Heart Lung Transplant 20:696-8. 2001
    ..We also believe that the patient's history of high-dose vitamin C usage may have accelerated iron deposition in the heart and other vital organs...
  2. ncbi Early outcomes of a care coordination-enhanced telehome care program for elderly veterans with chronic heart failure
    Richard S Schofield
    Cardiology Section, Rehabilitation Outcomes Research Center, Department of Veterans Affairs Medical Center, Gainesville, Florida, USA
    Telemed J E Health 11:20-7. 2005
    ..Our nurse-directed, care coordinated home telehealth management program was associated with improved early outcomes in a group of elderly male veterans with chronic HF...
  3. ncbi Left ventricular dysfunction after pericardiectomy for constrictive pericarditis
    Richard S Schofield
    Malcom Randall Veterans Administration Medical Center, Department of Medicine, University of Florida College of Medicine, Gainesville, USA
    Ann Thorac Surg 77:1449-51. 2004
    ....
  4. ncbi Role of metabolically active drugs in the management of ischemic heart disease
    R S Schofield
    Division of Cardiovascular Medicine, University of Florida College of Medicine, Gainesville, Florida 32610, USA
    Am J Cardiovasc Drugs 1:23-35. 2001
    ..Clinical trial data in acute myocardial infarction are promising and have prompted the initiation of a large-scale mortality trial...
  5. ncbi Cardiac transplantation in patients with anti-phospholipid antibodies
    Richard S Schofield
    Department of Veterans Affairs Medical Center, Gainesville, Florida, USA
    J Heart Lung Transplant 26:299-301. 2007
    ....
  6. ncbi Vascular effects of sildenafil in hypertensive cardiac transplant recipients
    Richard S Schofield
    Division of Cardiovascular Medicine and Shands Transplant Center, University of Florida College of Medicine, Gainesville, Florida 32610, USA
    Am J Hypertens 16:874-7. 2003
    ..Sildenafil is commonly used in the treatment of erectile dysfunction in hypertensive male cardiac transplant recipients (CTR); however, little is known about the vascular effects of sildenafil in these patients...
  7. ncbi Hyperhomocysteinemia in patients with heart failure referred for cardiac transplantation: preliminary observations
    Richard S Schofield
    Division of Cardiovascular Medicine and Shands Transplant Center, University of Florida College of Medicine, Gainesville, Florida, USA
    Clin Cardiol 26:407-10. 2003
    ..Hyperhomocysteinemia is becoming recognized as a risk factor for cardiovascular disease, yet there are limited data on the prevalence of hyperhomocysteinemia in patients with heart failure...
  8. ncbi Arterial-wave reflections are increased in heart failure patients with a left-ventricular assist device
    Richard S Schofield
    Department of Veterans Affairs Medical Center, Gainesville, Florida, USA
    Am J Hypertens 20:622-8. 2007
    ..Although the treatment of HF via left-ventricular assist device (LVAD) placement has recently become widespread, the effects of LVAD therapy on central arterial pulse-wave reflections are unknown...
  9. ncbi Amplitude and timing of central aortic pressure wave reflections in heart transplant recipients
    Richard S Schofield
    Division of Cardiovascular Medicine and Shands Transplant Center, University of Florida, College of Medicine, Gainesville, USA
    Am J Hypertens 15:809-15. 2002
    ..The aim of this study was to measure the central aortic pressure wave in HTR on antihypertensive therapy and determine the effects of amplitude and timing of wave reflection on the various components of the wave...
  10. ncbi Hormone therapy in men and risk of cardiac allograft rejection
    Richard S Schofield
    Division of Cardiovascular Medicine and University of Florida, Shands Transplant Center, University of Florida College of Medicine, Gainesville, Florida 32610, USA
    J Heart Lung Transplant 21:493-5. 2002
    ..To our knowledge, this is the first such description of this phenomenon in the literature...
  11. ncbi The use of ranolazine in cardiovascular disease
    Richard S Schofield
    Division of Cardiovascular Medicine, University of Florida College of Medicine, 1600 S W Archer Road, Box 100277, Gainesville, FL 32610, USA
    Expert Opin Investig Drugs 11:117-23. 2002
    ..The maker of ranolazine, CV Therapeutics (Palo Alto, California), will file a New Drug Application (NDA) with the US FDA for the approval of ranolazine as an anti-anginal in the near future...
  12. ncbi Beta1-adrenergic receptor polymorphisms and left ventricular remodeling changes in response to beta-blocker therapy
    Steven G Terra
    Department of Pharmacy Practice, University of Florida College of Pharmacy, Gainesville, FL 32610, USA
    Pharmacogenet Genomics 15:227-34. 2005
    ..We hypothesized that polymorphisms at codon 389 (Arg389Gly) and 49 (Ser49Gly) in the beta1-adrenergic receptor (AR) gene were associated with LV reverse remodeling changes in response to beta-blocker therapy among heart failure patients...
  13. ncbi Tricuspid annular motion as a predictor of severe right ventricular failure after left ventricular assist device implantation
    Sarinya Puwanant
    Division of Cardiovascular Medicine, Department of Internal Medicine, University of Florida, Gainesville, Florida, USA
    J Heart Lung Transplant 27:1102-7. 2008
    ..We sought to determine pre-operative right heart echocardiographic predictors of post-LVAD severe RV failure...
  14. ncbi Effects of exercise training on forearm and calf vasodilation and proinflammatory markers in recent heart transplant recipients: a pilot study
    Gary L Pierce
    Department of Applied Physiology and Kinesiology, College of Health and Human Performance, University of Florida, Gainesville, Florida, USA
    Eur J Cardiovasc Prev Rehabil 15:10-8. 2008
    ..It is, however, currently unknown whether aerobic exercise has a similar effect in heart transplant recipients (HTR)...
  15. ncbi Atorvastatin effect on circulating and leukocyte-produced CD40 ligand concentrations in people with normal cholesterol levels: a pilot study
    Issam Zineh
    Department of Pharmacy Practice and Center for Pharmacogenomics, College of Pharmacy, University of Florida, Gainesville, Florida 32610, USA
    Pharmacotherapy 26:1572-7. 2006
    ....
  16. ncbi Managing the post-left ventricular assist device patient
    Charles T Klodell
    Department of Surgery, University of Florida, Gainesville, FL 32610, USA
    Congest Heart Fail 12:41-5. 2006
    ..Key issues following the implantation of assist devices include the prevention of right ventricular failure, appropriate pharmacologic management, prevention and management of infection, and detection and treatment of device dysfunction...
  17. ncbi Modulatory effects of atorvastatin on endothelial cell-derived chemokines, cytokines, and angiogenic factors
    Issam Zineh
    Department of Pharmacy Practice, College of Pharmacy, University of Florida, Gainesville, Florida 32610, USA
    Pharmacotherapy 26:333-40. 2006
    ....
  18. ncbi CXCL5 gene polymorphisms are related to systemic concentrations and leukocyte production of epithelial neutrophil-activating peptide (ENA-78)
    Issam Zineh
    University of Florida College of Pharmacy, Department of Pharmacy Practice, 1600 SW Archer Road, Room PG 06, PO Box 100486, Gainesville, FL 32610, USA
    Cytokine 33:258-63. 2006
    ..Our findings add to the strength of CXCL5 as candidate gene in future disease-gene and pharmacogenetic association studies...
  19. ncbi Initial heart rate and systolic blood pressure predict outcomes in chronic heart failure patients who are evaluated for cardiac transplant
    Juan M Aranda
    University of Florida College of Medicine, Department of Medicine, Division of Cardiovascular Medicine, Gainesville, Florida, USA
    Clin Cardiol 30:282-7. 2007
    ..We sought to determine whether an initial hemodynamic profile of HR and SBP could be used to predict outcomes in chronic heart failure patients evaluated for Htx...
  20. ncbi Complementary and alternative medicine use among individuals participating in research: implications for research and practice
    Gregory J Welder
    Department of Pharmacy Practice and Center for Pharmacogenomics, College of Pharmacy, University of Florida, Gainesville, Florida 32610, USA
    Pharmacotherapy 26:1794-801. 2006
    ....
  21. ncbi Effect of sildenafil on pulmonary artery pressure, systemic pressure, and nitric oxide utilization in patients with left ventricular assist devices
    Charles T Klodell
    Department of Surgery, University of Florida College of Medicine, Gainesville, Florida, USA
    Ann Thorac Surg 83:68-71; discussion 71. 2007
    ..We evaluated the effect of oral sildenafil therapy on pulmonary artery pressure, systemic pressure, and nitric oxide utilization...
  22. ncbi Exercise training attenuates progressive decline in brachial artery reactivity in heart transplant recipients
    Randy W Braith
    Center for Exercise Science, Department of Applied Physiology and Kinesiology, College of Health and Human Performance, University of Florida, Gainesville, Florida 32611, USA
    J Heart Lung Transplant 27:52-9. 2008
    ..Heart transplantation normalizes central hemodynamics, but endothelial dysfunction persists after transplantation...
  23. ncbi Synergistic polymorphisms of beta1 and alpha2C-adrenergic receptors and the influence on left ventricular ejection fraction response to beta-blocker therapy in heart failure
    Maximilian T Lobmeyer
    Department of Pharmacy Practice, University of Florida, Gainesville, FL 32610, USA
    Pharmacogenet Genomics 17:277-82. 2007
    ..We tested whether the ADRA2C insertion/deletion polymorphism was associated with beta-blocker response in heart failure, either alone or in combination with the ADRB1Arg389Gly polymorphism...
  24. ncbi Management of heart failure after cardiac resynchronization therapy: integrating advanced heart failure treatment with optimal device function
    Juan M Aranda
    Division of Cardiovascular Medicine, College of Medicine, University of Florida Health Science Center, Gainesville, Florida, USA
    J Am Coll Cardiol 46:2193-8. 2005
    ..This algorithm represents a new, comprehensive, collaborative approach between the HF and electrophysiology specialists to further improve and sustain outcomes in the field of CRT...
  25. ncbi Dobutamine-related asthma in a patient awaiting cardiac transplantation: the eosinophilic dilemma
    Juan M Aranda
    Division of Cardiovascular Medicine, Shands Hospital, University of Florida, Gainesville, Florida 32610, USA
    J Heart Lung Transplant 23:260-1. 2004
    ..Once the patient was switched to an alternative inotrope, milrinone, the eosinophil count returned to normal, and the asthma exacerbation resolved...
  26. ncbi Anti-CD20 monoclonal antibody (rituximab) therapy for acute cardiac humoral rejection: a case report
    Juan M Aranda
    Department of Medicine, Division of Cardiovascular Medicine, University of Florida College of Medicine, Gainesville, FL 32610, USA
    Transplantation 73:907-10. 2002
    ..One year posttransplant, the patient is rejection-free, with normal left ventricular systolic function and coronary arteries...
  27. ncbi The evolving role of nesiritide in advanced or decompensated heart failure
    Issam Zineh
    Department of Pharmacy Practice, College of Pharmacy, University of Florida, P O Box 100486, Gainesville, FL 32610, USA
    Pharmacotherapy 23:1266-80. 2003
    ..In addition, recommendations for its administration are provided, and unresolved therapeutic considerations are discussed...
  28. ncbi Percutaneous coronary intervention versus medical therapy for coronary allograft vasculopathy. One center's experience
    Juan M Aranda
    Division of Cardiovascular Medicine, University of Florida College of Medicine, Gainesville, USA
    J Heart Lung Transplant 21:860-6. 2002
    ..We compared clinical outcomes in heart transplant recipients with coronary allograft vasculopathy who were treated either with percutaneous coronary intervention or with aggressive medical therapy alone...
  29. ncbi Ventricular dyssynchrony in dilated cardiomyopathy: the role of biventricular pacing in the treatment of congestive heart failure
    Juan M Aranda
    University of Florida Health Science Center, Division of Cardiovascular Medicine, Gainesville 32610 0277, USA
    Clin Cardiol 25:357-62. 2002
    ..This article reviews the pathophysiology of ventricular dyssynchrony and examine insights from clinical trials that are evaluating cardiac resynchronization therapy for CHF...
  30. ncbi Use of cardiac resynchronization therapy to optimize beta-blocker therapy in patients with heart failure and prolonged QRS duration
    Juan M Aranda
    Division of Cardiovascular Medicine, University of Florida College of Medicine, Gainesville, Florida, USA
    Am J Cardiol 95:889-91. 2005
    ....
  31. ncbi Comparison of dobutamine versus milrinone therapy in hospitalized patients awaiting cardiac transplantation: a prospective, randomized trial
    Juan M Aranda
    University of Florida College of Medicine, Division of Cardiovascular Medicine, the University of Florida Shands Transplant Center, Gainesville, FL 32610 0395, USA
    Am Heart J 145:324-9. 2003
    ..The costs and effectiveness of these drugs have yet to be compared in a prospective, randomized study...
  32. ncbi Sustained restoration of autonomic balance with long- but not short-acting metoprolol in patients with heart failure
    Christina L Aquilante
    Department of Pharmacy Practice, University of Florida College of Pharmacy, Gainesville, 32610, USA
    J Card Fail 12:171-6. 2006
    ..0005, respectively). CONCLUSION: These data suggest that with twice daily dosing, metoprolol IR is inferior to metoprolol XL in its effects on heart rate variability, autonomic balance, and blood pressure in patients with heart failure...
  33. ncbi Images in cardiology: a case of giant left atrium
    Richard S Schofield
    Division of Cardiovascular Medicine, University of Florida College of Medicine, Gainesville, Florida, USA
    Clin Cardiol 26:188. 2003
  34. ncbi Relation of beta(2)-adrenoceptor haplotype to risk of death and heart transplantation in patients with heart failure
    Jaekyu Shin
    College of Pharmacy, Gainesville, Florida, USA
    Am J Cardiol 99:250-5. 2007
    ..In conclusion, ADRB2 Arg16Gln27 haplotype may significantly increase the risk of adverse outcomes in patients with HF receiving contemporary HF pharmacotherapy...
  35. ncbi Appropriate evaluation and treatment of heart failure patients after implantable cardioverter-defibrillator discharge: time to go beyond the initial shock
    Joseph D Mishkin
    Division of Cardiovascular Medicine, University of Florida College of Medicine, Gainesville, Florida 32610, USA
    J Am Coll Cardiol 54:1993-2000. 2009
    ..Aggressive HF surveillance and management is required after an ICD shock, as the risk of sudden cardiac death is transformed to an increased HF event risk...
  36. ncbi Atrial fibrillation as a cause of left ventricular dysfunction after cardiac transplantation
    Gregory W Woo
    Division of Cardiovascular Medicine, University of Florida College of Medicine, Gainesville, Florida, USA
    J Heart Lung Transplant 25:131-3. 2006
    ..The onset of atrial fibrillation years after a heart transplant is not necessarily an indication of rejection. Aggressive rate control and restoration of normal sinus rhythm may improve allograft function in such cases...
  37. ncbi Constrictive pericarditis presenting as a calcified anterior cardiac mass
    Richard S Schofield
    Division of Cardiovascular Medicine, University of Florida, Gainesville, Florida, USA
    Ann Thorac Surg 87:1597-9. 2009
    ..Upon diagnosis of constrictive pericarditis, the patient underwent pericardectomy and resection of the mass. He is well 6 months postoperatively, with complete resolution of his heart failure symptoms...
  38. ncbi beta-Adrenergic receptor polymorphisms and responses during titration of metoprolol controlled release/extended release in heart failure
    Steven G Terra
    Department of Pharmacy Practice, University of Florida, Gainsville, FL 32610, USA
    Clin Pharmacol Ther 77:127-37. 2005
    ..We also tested whether polymorphisms in the beta(2)-adrenergic receptor, G-protein alpha s subunit (G(s)alpha), and cytochrome P450 (CYP) 2D6 genes or S-metoprolol plasma concentrations were associated with beta-blocker tolerability...
  39. ncbi Incidence, predictors, and outcomes of cardiac pacing after cardiac transplantation: an 11-year retrospective analysis
    Gregory W Woo
    Division of Cardiovascular Medicine, University of Florida College of Medicine, Gainesville, Florida 32610 0277, USA
    Transplantation 85:1216-8. 2008
    ..001). Approximately one fourth of cardiac transplant patients require permanent pacing. Surgical technique is a major predictor of who will require permanent pacing after cardiac transplantation...
  40. ncbi Mental stress provokes ischemia in coronary artery disease subjects without exercise- or adenosine-induced ischemia
    Srikanth Ramachandruni
    University of Florida, Gainesville, Florida 32608, USA
    J Am Coll Cardiol 47:987-91. 2006
    ..CONCLUSIONS: Mental stress may produce ischemia in some subjects with CAD and negative exercise or chemical nuclear stress test results...
  41. ncbi Pharmacological treatment of patients with peripheral arterial disease
    Chin K Kim
    Cardiology Section, Department of Veterans Affairs, Medical Service, Malcom Randall VA Medical Center, Gainesville, Florida, USA
    Drugs 63:637-47. 2003
    ..With aggressive risk factor modification and adequate pharmacotherapy, patients with peripheral arterial disease can have an improved quality of life as well as prolonged survival...
  42. ncbi Dilated cardiomyopathy and acute liver injury associated with combined use of ephedra, gamma-hydroxybutyrate, and anabolic steroids
    Brychan M Clark
    Department of Medicine, Wilford Hall USAF Medical Center, San Antonio, TX 78236, USA
    Pharmacotherapy 25:756-61. 2005
    ....
  43. ncbi Association of diurnal blood pressure pattern with risk of hospitalization or death in men with heart failure
    Jaekyu Shin
    College of Pharmacy, University of Florida, Gainesville, Florida, USA
    J Card Fail 13:656-62. 2007
    ..We tested whether an altered diurnal BP pattern is associated with adverse outcomes (death or hospitalization for HF exacerbation) in patients with HF...
  44. ncbi Role of heart failure etiology on arterial wave reflection in heart transplant recipients: relation with C-reactive protein
    Gary L Pierce
    Department of Applied Physiology and Kinesiology, USA
    J Hypertens 25:2273-9. 2007
    ....
  45. ncbi Integrating complementary medicine into cardiovascular medicine. A report of the American College of Cardiology Foundation Task Force on Clinical Expert Consensus Documents (Writing Committee to Develop an Expert Consensus Document on Complementary and In
    John H K Vogel
    J Am Coll Cardiol 46:184-221. 2005
  46. ncbi Effect of exercise training on endothelial function in men with coronary artery disease
    David G Edwards
    Department of Kinesiology, University of New Hampshire, Durham, New Hampshire 03824, USA
    Am J Cardiol 93:617-20. 2004
    ..9% at baseline vs 11.1% at 12 weeks). Exercise training resulted in increased plasma nitrite and nitrate levels, increased plasma superoxide dismutase activity, and decreased oxidative stress...
  47. ncbi Effect of exercise training on central aortic pressure wave reflection in coronary artery disease
    David G Edwards
    Department of Kinesiology, University of New Hampshire, Durham, NH 03824, USA
    Am J Hypertens 17:540-3. 2004
    ..Arterial stiffness is an important factor for cardiovascular performance and a predictor of cardiovascular risk. We investigated the effect of exercise training on arterial stiffness in coronary artery disease (CAD)...
  48. ncbi ACCF/AHA/CDC conference report on emerging infectious diseases and biological terrorism threats: the clinical and public health implications for the prevention and control of cardiovascular diseases
    George A Mensah
    J Am Coll Cardiol 49:1373-412. 2007
  49. ncbi ACCF/AHA 2007 clinical expert consensus document on coronary artery calcium scoring by computed tomography in global cardiovascular risk assessment and in evaluation of patients with chest pain: a report of the American College of Cardiology Foundation Cl
    Philip Greenland
    Circulation 115:402-26. 2007
  50. ncbi ACCF/AHA/CDC conference report on emerging infectious diseases and biological terrorism threats: the clinical and public health implications for the prevention and control of cardiovascular diseases
    George A Mensah
    National Center for Chronic Disease Prevention and Health Promotion, Centers for Disease Control and Prevention, Atlanta, GA 30341-3717, USA
    Circulation 115:1656-95. 2007