Robert Schnoll

..This study suggests the need to examine novel psychological mechanisms that may account for the relationship between depression symptoms and smoking cessation...

..Thus, faster metabolizers of nicotine may require a higher nicotine patch dose to achieve cessation...

..This study evaluated whether extended vs. standard duration treatment with nicotine patch helps those able to quit smoking to reduce cessation-induced weight gain and explored nicotine patch adherence as a mediator of treatment effects...

..Barriers to the translation of this research to clinical practice are discussed, as are directions for future research...

..As this research advances, it will be important to study and address practical, economic, ethical, and social barriers to the translation of genetics research on tobacco use to clinical practice...

..Greater attention to the unique needs of female smokers may allow healthcare providers to optimize delivery of pharmacotherapy and behavioral counseling to aid their female patients to quit smoking...

..We conclude this paper with a summary and a brief discussion of the major caveats of this literature and priorities for future research...

..Modafinil (Provigil), a wakefulness medication shown to have efficacy for the treatment of cocaine addiction, was tested as a novel therapy for nicotine dependence in a double-blind placebo-controlled trial...

..38, t[355]=-3.09, p<.05). These data support the value of the 3-HC/cotinine ratio as a biomarker to predict success with transdermal nicotine for smoking cessation...

..This study compared the effectiveness of transdermal nicotine vs. nicotine lozenge for smoking cessation and identified predictors of treatment response...

..Many cancer patients continue to smoke post diagnosis, yet there have been few smoking cessation trials for this population. Depression, which is prevalent among cancer patients, may be a barrier to cessation...

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..Little attention has been paid to tobacco use among cancer patients in developing countries, including Russia, where tobacco use is extremely high, and there is little public health infrastructure to address this issue...

..This article describes barriers to clinical integration of pharmacogenetic treatments that will need to be addressed to realize the benefits of individualized smoking-cessation treatment...

..There was no evidence for mediation. In bupropion smoking cessation trials, blind failure may occur and participant guess about treatment arm assignment is associated with quit rates...

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..Public health and government organizations have invested considerably to increase physician adherence to smoking-cessation practice guidelines...

..Identifying prospective predictors of smoking cessation among patients currently receiving smoking cessation treatment can help guide the development and implementation of smoking cessation programs with this population...

..A larger clinical trial to evaluate a genetic prime message for improving recruitment into smoking cessation programs is warranted...

..Larger-scale investigations that incorporate pathway-based or genome-wide analysis, as well as intermediate measures of nicotine dependence (i.e. 'endophenotypes'), may be necessary to capture the complexity of pharmacogenetic effects...

..g., during a celebration; F[7,600]=9.05, p<.05). These findings can be used to refine behavioral smoking cessation interventions to increase self-efficacy to quit smoking...

..Enhanced understanding of these dimensions of nicotine dependence may help to advance progress toward lowering the prevalence rate of tobacco use in the U.S. and lowering the rate of tobacco-related morbidity and mortality...

..However, additional trials including larger and more diverse populations are needed before such data can be translated to practice to reduce smoking prevalence and tobacco-related disease...

..In sum, this study fills a critical gap in knowledge concerning the epidemic of tobacco use in Russia and broadens research regarding tobacco use by cancer patients from the United States to the Russian Federation...

..Tobacco dependence is a chronic, relapsing condition that may require extended treatment...

..Recruitment strategies are needed for patients with advanced disease and specific cancers. Once enrolled, addressing participant's depressive symptoms is critical for promoting cessation...

..Modifiable cancer risk factors can be identified in the majority of workers. Inaccurate risk perception is an important target for future interventions...

..A fraction of smokers considered eligible for pharmacotherapy treatment trials for nicotine dependence enrolled. Little is known about smokers not enrolling in a treatment trial or how these smokers differ from those who have enrolled...

..Because patients have regular contact with oncologists, the efficacy of a physician-based smoking cessation treatment was evaluated...

..These results can be used to guide the development of smoking cessation training programs for Russian physicians...

..These strategies are discussed within the context of models and guidelines for smoking cessation in clinical practice...

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..We examined reasons patients provide for declining smoking treatment and compared treatment decliners to enrollees...

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..continuous smokers exhibited a significantly lower level of risk perceptions than continuous abstainers. These findings can be useful for the development and evaluation of treatments to promote smoking cessation among cancer patients...

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..These findings can help guide the development of smoking cessation interventions for cancer patients...

..To pilot a worksite smoking intervention...

..This study could clarify the TM concept for smoking cessation, shed light on the underlying mechanisms of TMs, and guide future development and implementation of TM-based smoking cessation interventions. ..

..g., promotion of recovery following a lapse) for maintenance therapy with transdermal nicotine will also be assessed. The study results may change how we treat nicotine dependence with transdermal nicotine. ..

..This study could clarify the TM concept for smoking cessation, shed light on the underlying mechanisms of TMs, and guide future development and implementation of TM-based smoking cessation interventions. ..

..This study could clarify the TM concept for smoking cessation, shed light on the underlying mechanisms of TMs, and guide future development and implementation of TM-based smoking cessation interventions. ..

..In turn, our findings may help guide the implementation of smoking cessation treatments for all cancer patients within Comprehensive Cancer Centers in the US. ..

..g., promotion of recovery following a lapse) for maintenance therapy with transdermal nicotine will also be assessed. The study results may change how we treat nicotine dependence with transdermal nicotine. ..