H J Schünemann

Summary

Affiliation: University at Buffalo
Country: USA

Publications

  1. ncbi request reprint Systematic reviews for the Journal of Experimental & Clinical Cancer Research: going where the science takes us
    H J Schünemann
    National Cancer Institute Regina Elena, Rome, Italy
    J Exp Clin Cancer Res 26:169-74. 2007
  2. pmc LOST to follow-up Information in Trials (LOST-IT): a protocol on the potential impact
    Elie A Akl
    Department of Medicine, State University of New York at Buffalo, Buffalo, USA
    Trials 10:40. 2009
  3. pmc Stopping randomized trials early for benefit: a protocol of the Study Of Trial Policy Of Interim Truncation-2 (STOPIT-2)
    Matthias Briel
    Department of Clinical Epidemiology and Biostatistics, McMaster University, Hamilton, Canada
    Trials 10:49. 2009
  4. pmc Value of supplemental interventions to enhance the effectiveness of physical exercise during respiratory rehabilitation in COPD patients. A systematic review
    Milo A Puhan
    University of Zurich, Horten Centre, Switzerland
    Respir Res 5:25. 2004
  5. pmc Urinary estrogen metabolites and prostate cancer: a case-control study and meta-analysis
    Maddalena Barba
    Department of Epidemiology, National Cancer Institute Regina Elena, Rome, Italy
    J Exp Clin Cancer Res 28:135. 2009
  6. pmc Low-molecular-weight heparins are superior to vitamin K antagonists for the long term treatment of venous thromboembolism in patients with cancer: a cochrane systematic review
    Elie A Akl
    Department of Medicine, State University of New York at Buffalo, Buffalo, NY, USA
    J Exp Clin Cancer Res 27:21. 2008
  7. pmc Parenteral anticoagulation may prolong the survival of patients with limited small cell lung cancer: a Cochrane systematic review
    Elie A Akl
    Department of Medicine, State University of New York at Buffalo, NY, USA
    J Exp Clin Cancer Res 27:4. 2008
  8. pmc Internal consistency reliability is a poor predictor of responsiveness
    Milo A Puhan
    Horten Centre, University Hospital, Postfach Nord, 8091 Zurich, Switzerland
    Health Qual Life Outcomes 3:33. 2005
  9. pmc Self-administration and interviewer-administration of the German Chronic Respiratory Questionnaire: instrument development and assessment of validity and reliability in two randomised studies
    Milo A Puhan
    Horten Centre, University Hospital of Zurich, Postfach Nord CH 8091 Zurich, Switzerland
    Health Qual Life Outcomes 2:1. 2004
  10. pmc Combining scores from different patient reported outcome measures in meta-analyses: when is it justified?
    Milo A Puhan
    Horten Centre, University of Zurich, Switzerland
    Health Qual Life Outcomes 4:94. 2006

Research Grants

Collaborators

Detail Information

Publications69

  1. ncbi request reprint Systematic reviews for the Journal of Experimental & Clinical Cancer Research: going where the science takes us
    H J Schünemann
    National Cancer Institute Regina Elena, Rome, Italy
    J Exp Clin Cancer Res 26:169-74. 2007
  2. pmc LOST to follow-up Information in Trials (LOST-IT): a protocol on the potential impact
    Elie A Akl
    Department of Medicine, State University of New York at Buffalo, Buffalo, USA
    Trials 10:40. 2009
    ..The secondary objectives are to describe, for published RCTs, (1) the reporting of loss to follow-up information, (2) the analytic methods used for handling loss to follow-up information, and (3) the extent of reported loss to follow-up...
  3. pmc Stopping randomized trials early for benefit: a protocol of the Study Of Trial Policy Of Interim Truncation-2 (STOPIT-2)
    Matthias Briel
    Department of Clinical Epidemiology and Biostatistics, McMaster University, Hamilton, Canada
    Trials 10:49. 2009
    ..The aim of STOPIT-2 is to determine the magnitude and determinants of possible bias introduced by stopping RCTs early for benefit...
  4. pmc Value of supplemental interventions to enhance the effectiveness of physical exercise during respiratory rehabilitation in COPD patients. A systematic review
    Milo A Puhan
    University of Zurich, Horten Centre, Switzerland
    Respir Res 5:25. 2004
    ..The aim of this research was to assess randomised controlled trials (RCTs) testing the additional benefit of supplemental interventions during respiratory rehabilitation in COPD patients...
  5. pmc Urinary estrogen metabolites and prostate cancer: a case-control study and meta-analysis
    Maddalena Barba
    Department of Epidemiology, National Cancer Institute Regina Elena, Rome, Italy
    J Exp Clin Cancer Res 28:135. 2009
    ..To investigate prostate cancer (Pca) risk in relation to estrogen metabolism, expressed as urinary 2-hydroxyestrone (2-OHE1), 16alpha-hydroxyestrone (16alpha-OHE1) and 2-OHE1 to 16alpha-OHE1 ratio...
  6. pmc Low-molecular-weight heparins are superior to vitamin K antagonists for the long term treatment of venous thromboembolism in patients with cancer: a cochrane systematic review
    Elie A Akl
    Department of Medicine, State University of New York at Buffalo, Buffalo, NY, USA
    J Exp Clin Cancer Res 27:21. 2008
    ..The objective of this study was to compare low molecular weight heparin (LMWH) and oral anticoagulants (vitamin K antagonist (VKA) and ximelagatran) for the long term treatment of venous thromboembolism in patients with cancer...
  7. pmc Parenteral anticoagulation may prolong the survival of patients with limited small cell lung cancer: a Cochrane systematic review
    Elie A Akl
    Department of Medicine, State University of New York at Buffalo, NY, USA
    J Exp Clin Cancer Res 27:4. 2008
    ..To determine the efficacy and safety of heparin (unfractionated heparin (UFH) or low-molecular-weight-heparin (LMWH)) and fondaparinux in improving the survival of patients with cancer...
  8. pmc Internal consistency reliability is a poor predictor of responsiveness
    Milo A Puhan
    Horten Centre, University Hospital, Postfach Nord, 8091 Zurich, Switzerland
    Health Qual Life Outcomes 3:33. 2005
    ..We addressed the claims of a recent study, which suggested that investigators could rely on internal consistency to reflect instrument responsiveness...
  9. pmc Self-administration and interviewer-administration of the German Chronic Respiratory Questionnaire: instrument development and assessment of validity and reliability in two randomised studies
    Milo A Puhan
    Horten Centre, University Hospital of Zurich, Postfach Nord CH 8091 Zurich, Switzerland
    Health Qual Life Outcomes 2:1. 2004
    ....
  10. pmc Combining scores from different patient reported outcome measures in meta-analyses: when is it justified?
    Milo A Puhan
    Horten Centre, University of Zurich, Switzerland
    Health Qual Life Outcomes 4:94. 2006
    ....
  11. pmc The influence of demographic factors and health-related quality of life on treatment satisfaction in patients with gastroesophageal reflux disease treated with esomeprazole
    Alessio Degl' Innocenti
    AstraZeneca R and D, 431 83 Mölndal, Sweden
    Health Qual Life Outcomes 3:4. 2005
    ..The objective of this study was to assess correlates of treatment satisfaction in patients with GERD receiving a proton pump inhibitor, esomeprazole...
  12. pmc Detecting myocardial infarction in critical illness using screening troponin measurements and ECG recordings
    Wendy Lim
    Department of Medicine, McMaster University, Canada
    Crit Care 12:R36. 2008
    ..This is a prospective screening study...
  13. pmc Post-graduation migration intentions of students of Lebanese medical schools: a survey study
    Elie A Akl
    Department of Medicine, University at Buffalo, NY, USA
    BMC Public Health 8:191. 2008
    ..Given that residency training abroad is a critical step in the migration of physicians, the objective of this study was to survey students of Lebanese medical schools about their intentions to train abroad and their post training plans...
  14. pmc A decision aid for COPD patients considering inhaled steroid therapy: development and before and after pilot testing
    Elie A Akl
    Department of Medicine, University at Buffalo, Buffalo, NY, USA
    BMC Med Inform Decis Mak 7:12. 2007
    ..An area not covered by a DA is the decision of a patient with chronic obstructive pulmonary disease (COPD) to use inhaled steroids which requires balancing the benefits and downsides of therapy...
  15. pmc An educational game for teaching clinical practice guidelines to Internal Medicine residents: development, feasibility and acceptability
    Elie A Akl
    Department of Medicine, State University of New York at Buffalo, NY, USA
    BMC Med Educ 8:50. 2008
    ..The objectives of this study were to develop an educational game to teach CPGs in Internal Medicine residency programs and to evaluate its feasibility and acceptability...
  16. pmc Graduates of Lebanese medical schools in the United States: an observational study of international migration of physicians
    Elie A Akl
    Department of Medicine, University at Buffalo, NY, USA
    BMC Health Serv Res 7:49. 2007
    ....
  17. pmc Systems for grading the quality of evidence and the strength of recommendations II: pilot study of a new system
    David Atkins
    Center for Practice and Technology Assessment, Agency for Healthcare Research and Quality, 540 Gaither Rd Rokville, MD 20852, USA
    BMC Health Serv Res 5:25. 2005
    ..The GRADE Working Group has developed an approach that addresses key shortcomings in these systems. The aim of this study was to pilot test and further develop the GRADE approach to grading evidence and recommendations...
  18. pmc Systems for grading the quality of evidence and the strength of recommendations I: critical appraisal of existing approaches The GRADE Working Group
    David Atkins
    Center for Practice and Technology Assessment, Agency for Healthcare Research and Quality, 540 Gaither Rd Rockville, MD 20852, USA
    BMC Health Serv Res 4:38. 2004
    ....
  19. ncbi request reprint Pulmonary function is a long-term predictor of mortality in the general population: 29-year follow-up of the Buffalo Health Study
    H J Schünemann
    Department of Social and Preventive Medicine, School of Medicine and Biomedical Sciences, State University of New York at Buffalo, NY 14214 3000, USA
    Chest 118:656-64. 2000
    ..The purpose of this study was to investigate the predictive value of pulmonary function by gender after 29 years of follow-up...
  20. doi request reprint Methodology for antithrombotic and thrombolytic therapy guideline development: American College of Chest Physicians Evidence-based Clinical Practice Guidelines (8th Edition)
    Holger J Schunemann
    Department of Epidemiology, Italian National Cancer Institute Regina Elena, Via Elio Chianesi 53, Rome, Italy
    Chest 133:113S-122S. 2008
    ..In combination with our previous practice of grading recommendations according to their strength and the methodologic quality of the supporting studies, these methods establish our guideline methodology as evidence based...
  21. ncbi request reprint Antithrombotic and thrombolytic therapy: from evidence to application: the Seventh ACCP Conference on Antithrombotic and Thrombolytic Therapy
    Holger J Schunemann
    Department of Medicine, University at Buffalo, ECMC CC142, 462 Grider St, Buffalo, NY 14215, USA
    Chest 126:688S-696S. 2004
    ..Fully informed decisions will require additional research to identify effective guideline implementation strategies to optimize antithrombotic and thrombolytic therapy...
  22. ncbi request reprint Methodology for guideline development for the Seventh American College of Chest Physicians Conference on Antithrombotic and Thrombolytic Therapy: the Seventh ACCP Conference on Antithrombotic and Thrombolytic Therapy
    Holger J Schunemann
    Department of Medicine, Division of General Internal Medicine, University at Buffalo, ECMC CC 142, 462 Grider St, Buffalo, NY 14226, USA
    Chest 126:174S-178S. 2004
    ..In combination with our previous practice of grading recommendations according to their strength, and the methodological quality of the supporting studies, these innovations establish our guidelines as, by and large, evidence based...
  23. pmc Letters, numbers, symbols and words: how to communicate grades of evidence and recommendations
    Holger J Schunemann
    Department of Medicine, University of Buffalo, Buffalo, NY, USA
    CMAJ 169:677-80. 2003
    ..Before promoting the use of specific symbols, numbers, letters or words, the extent to which the intended message is comprehended should be evaluated...
  24. ncbi request reprint The relation of serum levels of antioxidant vitamins C and E, retinol and carotenoids with pulmonary function in the general population
    H J Schünemann
    Department of Social and Preventive Medicine, and Department of Medicine, Division of Pulmonary, Critical Care and Sleep Medicine, School of Medicine and Biomedical Sciences, State University of New York at Buffalo, Buffalo, New York, USA
    Am J Respir Crit Care Med 163:1246-55. 2001
    ..Our findings support the hypothesis that antioxidant vitamins may play a role in respiratory health and that vitamin E and beta-cryptoxanthin appear to be stronger correlates of lung function than other antioxidant vitamins...
  25. ncbi request reprint Lung function in relation to intake of carotenoids and other antioxidant vitamins in a population-based study
    Holger J Schunemann
    Department of Medicine, School of Medicine and Biomedical Sciences, State University of New York, 207 Farber Hall, 3435 Main Street, Buffalo, NY 14214 3000, USA
    Am J Epidemiol 155:463-71. 2002
    ..Their findings support the hypothesis that carotenoids, vitamin C, and vitamin E may play a role in respiratory health and that carotenoids other than beta-carotene may be involved...
  26. ncbi request reprint Antioxidants, oxidative stress, and pulmonary function in individuals diagnosed with asthma or COPD
    H M Ochs-Balcom
    Department of Social and Preventive Medicine, School of Public Health and Health Professions, University at Buffalo, Buffalo, NY, USA
    Eur J Clin Nutr 60:991-9. 2006
    ..The objective of this study was to investigate the association between antioxidant nutrients and markers of oxidative stress with pulmonary function in persons with chronic airflow limitation...
  27. doi request reprint Grading quality of evidence and strength of recommendations in clinical practice guidelines. Part 1 of 3. An overview of the GRADE approach and grading quality of evidence about interventions
    J L Brozek
    Department of Epidemiology, Italian National Cancer Institute Regina Elena, Rome, Italy
    Allergy 64:669-77. 2009
    ..The system classifies quality of evidence as high, moderate, low, or very low according to factors that include the study methodology, consistency and precision of the results, and directness of the evidence...
  28. ncbi request reprint Is being breastfed as an infant associated with adult pulmonary function?
    Aasma Shaukat
    Department of Medicine, University at Buffalo, State University of New York, USA
    J Am Coll Nutr 24:327-33. 2005
    ..Our aim was to determine whether a history of having been breastfed as an infant is a determinant of adult pulmonary function...
  29. ncbi request reprint Oxidative stress and pulmonary function in the general population
    Heather M Ochs-Balcom
    Department of Social and Preventive Medicine, School of Public Health and Health Professions, University at Buffalo, Buffalo, NY, USA
    Am J Epidemiol 162:1137-45. 2005
    ..These results suggest that oxidative stress may be associated with airflow limitation in men, and that gender differences may exist in the relation of oxidative stress to pulmonary function...
  30. pmc A survey of internal medicine residents and faculty about the duration of attendings' inpatient rotations
    Elie A Akl
    Department of Medicine, University at Buffalo, NY 14215, USA
    J Gen Intern Med 19:1133-9. 2004
    ..Our objective was to determine the effect of 2-week inpatient rotation on self-reported impact on medical education, patient care practices, and faculty performance by internal medicine residents and teaching faculty...
  31. ncbi request reprint Oral anticoagulation may prolong survival of a subgroup of patients with cancer: a cochrane systematic review
    E A Akl
    Department of Medicine, State University of New York at Buffalo, NY 14215, USA
    J Exp Clin Cancer Res 26:175-84. 2007
    ..34; 95% CI 1.66-6.74). The evidence suggests a survival benefit from warfarin in patients with extensive SCLC, but not in other patient groups. This survival benefit should be weighed against the increased risk for hemorrhage...
  32. ncbi request reprint Markers of insulin resistance and sex steroid hormone activity in relation to breast cancer risk: a prospective analysis of abdominal adiposity, sebum production, and hirsutism (Italy)
    P Muti
    Divisione di Epidemiologia, Istituto Nazionale per lo Studio e la Cura dei Tumori, Milan, Italy
    Cancer Causes Control 11:721-30. 2000
    ....
  33. pmc Brief report: Internal medicine residents', attendings', and nurses' perceptions of the night float system
    Elie A Akl
    Department of Medicine, University at Buffalo, NY 14215, USA
    J Gen Intern Med 21:494-7. 2006
    ..Residency training programs use the night float system increasingly to meet the new resident work hour regulations...
  34. doi request reprint Low-molecular-weight heparin vs unfractionated heparin for perioperative thromboprophylaxis in patients with cancer: a systematic review and meta-analysis
    Elie A Akl
    Department of Medicine, State University of New York at Buffalo, Erie County Medical Center CC 142, 462 Grider St, Buffalo, NY 14215, USA
    Arch Intern Med 168:1261-9. 2008
    ..We systematically reviewed the literature to quantify these effects...
  35. ncbi request reprint Integrating an evidence-based medicine rotation into an internal medicine residency program
    Elie A Akl
    Department of Medicine, University at Buffalo, ECMC CC 142, 462 Grider St, Buffalo, NY 14215, USA
    Acad Med 79:897-904. 2004
    ..To measure the impact of a resident focused evidence-based medicine (EBM) educational intervention on EBM knowledge of residents and students, to assess its feasibility, and to evaluate residents' attitudes regarding this rotation...
  36. doi request reprint Anticoagulation for the initial treatment of venous thromboembolism in patients with cancer: a systematic review
    Elie A Akl
    Department of Medicine, State University of New York at Buffalo, Buffalo, New York 14215, USA
    Cancer 113:1685-94. 2008
    ..The authors compared the relative efficacy and safety of low-molecular-weight heparin (LMWH) and unfractionated heparin (UFH) for the initial treatment of venous thromboembolism (VTE) between patients with and without cancer...
  37. ncbi request reprint Relation between lung function and RBC distribution width in a population-based study
    Brydon J B Grant
    Veterans Affairs Western New York Health Care System, Veterans Affairs Medical Center, Buffalo, New York 14215, USA
    Chest 124:494-500. 2003
    ..Since an increased RBC distribution width (RDW) has been associated with nutritional deficiencies, we postulated that RDW has an inverse relation to pulmonary function. The purpose of this study was to test this hypothesis...
  38. ncbi request reprint Extended perioperative thromboprophylaxis in patients with cancer. A systematic review
    Elie A Akl
    Department of Medicine, State University of New York at Buffalo, ECMC CC 142, 462 Grider St, Buffalo, NY 14215, USA
    Thromb Haemost 100:1176-80. 2008
    ..More and better quality evidence is needed to justify extended regimens...
  39. ncbi request reprint Anticoagulation in patients with cancer: an overview of reviews
    Elie A Akl
    Department of Medicine, State University of New York at Buffalo, NY 14215, USA
    Pol Arch Med Wewn 118:183-93. 2008
    ..Relative benefits and harms of anticoagulants are required for judgments regarding appropriate anticoagulation in patients with cancer...
  40. doi request reprint The effect of educational games on medical students' learning outcomes: a systematic review: BEME Guide No 14
    Elie A Akl
    State University of New York, Buffalo, NY, USA
    Med Teach 32:16-27. 2010
    ..An educational game is 'an instructional method requiring the learner to participate in a competitive activity with preset rules.' A number of studies have suggested beneficial effects of educational games in medical education...
  41. pmc Support for and aspects of use of educational games in family medicine and internal medicine residency programs in the US: a survey
    Elie A Akl
    Department of Medicine, State University of New York at Buffalo, Buffalo, NY, USA
    BMC Med Educ 10:26. 2010
    ..The objective of this study was to explore the support for and the different aspects of use of educational games in family medicine and internal medicine residency programs in the United States...
  42. doi request reprint Thromboprophylaxis for patients with cancer and central venous catheters: a systematic review and a meta-analysis
    Elie A Akl
    Department of Medicine, State University of New York at Buffalo, Buffalo, NY 14215, USA
    Cancer 112:2483-92. 2008
    ..The objective of this systematic review was to determine the efficacy and safety of anticoagulation in reducing mortality and thromboembolic events in cancer patients with a CVC...
  43. pmc The effects of tracking responses and the day of mailing on physician survey response rate: three randomized trials
    Elie A Akl
    Department of Medicine, State University of New York at Buffalo, Buffalo, New York, United States of America
    PLoS ONE 6:e16942. 2011
    ..e., determining whether each potential participant has responded or not). A secondary objective was to assess the effects of day of mailing (Monday vs. Friday) on physician survey response rate...
  44. ncbi request reprint Why are you draining your brain? Factors underlying decisions of graduating Lebanese medical students to migrate
    Elie A Akl
    Department of Medicine, State University of New York at Buffalo, ECMC CC 142, 462 Grider Street, Buffalo, NY 14215, USA
    Soc Sci Med 64:1278-84. 2007
    ..The marketing of abroad training and the culture of migration are prevalent in the academic institutions...
  45. pmc The United States physician workforce and international medical graduates: trends and characteristics
    Elie A Akl
    Department of Medicine, School of Medicine and Biomedical Sciences, University at Buffalo, Buffalo, NY 14215, USA
    J Gen Intern Med 22:264-8. 2007
    ..International medical graduates (IMGs) have been a valuable resource for the United States physician workforce, and their contribution to the United States workforce is likely to increase...
  46. pmc Educational games in geriatric medicine education: a systematic review
    Ziad Alfarah
    Geriatrics Section, Department of Medicine, Boston University, Boston, MA, USA
    BMC Geriatr 10:19. 2010
    ..To systematically review the medical literature to assess the effect of geriatric educational games on the satisfaction, knowledge, beliefs, attitudes and behaviors of health care professionals...
  47. ncbi request reprint EBM user and practitioner models for graduate medical education: what do residents prefer?
    Elie A Akl
    Department of Sociology, University at Buffalo, State University of NY, Buffalo, NY, USA
    Med Teach 28:192-4. 2006
    ..The user model had the advantage of reduced time requirements. In sum, the majority of residents preferred a curriculum that focuses on the practitioner over the user model...
  48. ncbi request reprint Evidence for a positive association between pulmonary function and wine intake in a population-based study
    Holger J Schunemann
    Department of Medicine, Division of Pulmonary, Critical Care, and Sleep Medicine, School of Medicine and Biomedical Sciences, State University of New York, Buffalo, New York 14214 3000, USA
    Sleep Breath 6:161-73. 2002
    ..We analyzed the relation of beverage-specific alcohol intake with forced expiratory volume in one second (FEV1) and forced vital capacity (FVC) in a random sample of 1555 residents of Western New York, USA...
  49. ncbi request reprint Pulmonary function and abdominal adiposity in the general population
    Heather M Ochs-Balcom
    INFORMA, National Cancer Institute Regina Elena, Rome, Via Elio Chianesi 53, 00144 Rome, Italy
    Chest 129:853-62. 2006
    ..The mechanism for this association and the best marker of abdominal adiposity in relation to pulmonary function is not known...
  50. pmc Interpreting the results of patient reported outcome measures in clinical trials: the clinician's perspective
    Holger J Schunemann
    Division of Clinical Research Development and INFORMAtion Translation, Department of Epidemiology, Istituto Regina Elena Italian National Cancer Institute Rome, Rome, Italy
    Health Qual Life Outcomes 4:62. 2006
    ..Thus, there are several steps investigators can take to facilitate this process to help bringing HRQL information closer to the bedside...
  51. ncbi request reprint Evaluation of the minimal important difference for the feeling thermometer and the St. George's Respiratory Questionnaire in patients with chronic airflow obstruction
    Holger J Schunemann
    Department of Medicine, School of Medicine and Biomedical Sciences, State University of New York at Buffalo, 462 Grider Street, Buffalo, NY 14215, USA
    J Clin Epidemiol 56:1170-6. 2003
    ..The objective of our study is to explore the interpretation of the SGRQ and FT...
  52. doi request reprint Grading quality of evidence and strength of recommendations in clinical practice guidelines: Part 2 of 3. The GRADE approach to grading quality of evidence about diagnostic tests and strategies
    J L Brozek
    Department of Epidemiology, Italian National Cancer Institute Regina Elena, Rome, Italy
    Allergy 64:1109-16. 2009
    ..Well-designed and conducted studies of allergy tests in parallel with efforts to evaluate allergy treatments critically will encourage improved guideline development for allergic diseases...
  53. ncbi request reprint A novel approach for quality control of total lung capacity in the clinical pulmonary function laboratory: a study in a veteran population
    Holger J Schunemann
    Department of Medicine, School of Medicine and Biomedical Sciences, State University of New York at Buffalo, Buffalo, New York, USA
    Respirology 8:365-70. 2003
    ..Second, we measured the test-retest variability of TLCb, TLCm and TLC measured by single breath helium dilution (TLCs) to assess the consistency of the measurements...
  54. ncbi request reprint Symbols were superior to numbers for presenting strength of recommendations to health care consumers: a randomized trial
    Elie A Akl
    Department of Medicine, University at Buffalo, NY, USA
    J Clin Epidemiol 60:1298-305. 2007
    ..To compare health care consumers' understanding, evaluations, and preferences for symbols vs. numbers and letters for the representation of strength of recommendations (SOR) and quality of evidence (QOE)...
  55. pmc Grading quality of evidence and strength of recommendations for diagnostic tests and strategies
    Holger J Schunemann
    Department of Epidemiology, Italian National Cancer Institute Regina Elena, 00144 Rome, Italy
    BMJ 336:1106-10. 2008
  56. ncbi request reprint A clinical trial to evaluate the measurement properties of 2 direct preference instruments administered with and without hypothetical marker states
    Holger J Schunemann
    Department of Medicine, School of Medicine and Biomedical Sciences, State University of New York at Buffalo, Buffalo, NY, USA
    Med Decis Making 23:140-9. 2003
    ..However, there is no evidence to support improvement in measurement properties with the use of CMS. The authors evaluated validity and responsiveness of the SG and FT with and without administration of the CMS...
  57. ncbi request reprint Can contraindications compromise evidence-based, patient-centered clinical practice?
    Victor M Montori
    Knowledge and Encounter Research Unit, Department of Medicine, Mayo Clinic College of Medicine, Rochester, Minnesota, USA
    Can J Clin Pharmacol 13:e92-101. 2006
    ..The impact of contraindications on treatment decisions remains unexplored...
  58. ncbi request reprint A randomized multicenter trial to evaluate simple utility elicitation techniques in patients with gastroesophageal reflux disease
    Holger J Schunemann
    Department of Medicine, School of Medicine and Biomedical Sciences, University at Buffalo, State University of New York, Buffalo, New York, USA
    Med Care 42:1132-42. 2004
    ..We evaluated whether the administration of marker states improves measurement properties of the FT and SG...
  59. pmc Urinary 6-sulfatoxymelatonin levels and risk of breast cancer in postmenopausal women
    Eva S Schernhammer
    Channing Laboratory, Department of Medicine, Brigham and Women s Hospital and Harvard Medical School, 181 Longwood Ave, Boston, MA 02115, USA
    J Natl Cancer Inst 100:898-905. 2008
    ..Low urinary melatonin levels have been associated with an increased risk of breast cancer in premenopausal women. However, the association between melatonin levels and breast cancer risk in postmenopausal women remains unclear...
  60. ncbi request reprint Electronic mail was not better than postal mail for surveying residents and faculty
    Elie A Akl
    Department of Medicine, State University of New York, University at Buffalo, ECMC CC 142, 462 Grider Street, Buffalo, NY 14215, USA
    J Clin Epidemiol 58:425-9. 2005
    ..To compare response rate, time to response, and data quality of electronic and postal surveys in the setting of postgraduate medical education...
  61. ncbi request reprint Application of generalizability theory confirmed lower reliability of the standard gamble than the feeling thermometer
    Holger J Schunemann
    Department of Epidemiology, INFORMA Unit CLARITY Research Group, Italian National Cancer Institute Regina Elena, Via Elio Chianesi 53, 00144 Rome, Italy
    J Clin Epidemiol 60:1256-62. 2007
    ..Further, lack of interrater reliability may compromise the use of CMS in interpreting health state ratings. The aim of this study was to assess the reliability of CMS ratings for the SG and the FT...
  62. ncbi request reprint Do clinical marker states improve responsiveness and construct validity of the standard gamble and feeling thermometer: a randomized multi-center trial in patients with chronic respiratory disease
    Holger J Schunemann
    Division of Clinical Research Development and INFORMAtion Translation INFROMA, Italian National Cancer Institute Regina Elena, Rome, Italy
    Qual Life Res 15:1-14. 2006
    ..We evaluated the impact of clinical marker state (CMS) rating prior to patients' rating their own health on two utility instruments (feeling thermometer (FT) and standard gamble (SG)) in patients with chronic respiratory disease (CRD)...
  63. pmc Association between anemia and quality of life in a population sample of individuals with chronic obstructive pulmonary disease
    Gokul Krishnan
    Department of Medicine, School of Medicine and Biomedical Sciences, University at Buffalo, Buffalo, USA
    BMC Pulm Med 6:23. 2006
    ..However, there is little evidence regarding the association of anemia with HRQL in patients with chronic obstructive pulmonary disease (COPD)...
  64. ncbi request reprint Role of supplemental calcium in the recurrence of colorectal adenomas: a metaanalysis of randomized controlled trials
    Aasma Shaukat
    Department of Medicine, School of Medicine and Biomedical Sciences, State University of New York, 462 Grider Street, Buffalo, NY 14215, USA
    Am J Gastroenterol 100:390-4. 2005
    ..However, the role of calcium supplementation for preventing recurrence of adenomas is controversial. We performed a systematic review and meta-analysis to study the role of calcium supplementation in preventing recurrence of adenomas...
  65. ncbi request reprint A randomized controlled trial to evaluate the effect of informing patients about their pretreatment responses to two respiratory questionnaires
    Holger J Schunemann
    Department of Medicine, School of Medicine and Biomedical Sciences, The University at Buffalo, Buffalo, NY, USA
    Chest 122:1701-8. 2002
    ..George's Respiratory Questionnaire (SGRQ) with a 3-month interval between questionnaire completion...
  66. pmc Transparent development of the WHO rapid advice guidelines
    Holger J Schunemann
    Italian National Cancer Institute Regina Elena, Department of Epidemiology, Rome, Italy
    PLoS Med 4:e119. 2007
    ..The process could be improved by shortening the time required to commission evidence profiles. Further development is needed to facilitate stakeholder involvement, and evaluate and ensure the guideline's usefulness...
  67. doi request reprint Specific HRQL instruments and symptom scores were more responsive than preference-based generic instruments in patients with GERD
    Jan L Brozek
    Department of Epidemiology, CLARITY Research Group, Italian National Cancer Institute Regina Elena, Rome, Italy
    J Clin Epidemiol 62:102-10. 2009
    ..To determine relative responsiveness of disease-specific and generic preference-based health-related quality of life instruments in gastroesophageal reflux disease (GERD)...
  68. ncbi request reprint Measurement properties and interpretability of the Chronic respiratory disease questionnaire (CRQ)
    Holger J Schunemann
    Departments of Medicine, School of Medicine and Biomedical Sciences, University at Buffalo, State of New York, Buffalo, New York, USA
    COPD 2:81-9. 2005
    ..These objectives include the exploration of presentation of quality of life information and prospective anchor-based approaches...
  69. ncbi request reprint A comparison of the original chronic respiratory questionnaire with a standardized version
    Holger J Schunemann
    Department of Medicine, State University of New York at Buffalo, Buffalo, NY, USA
    Chest 124:1421-9. 2003
    ..Because the individualized domain is unwieldy in multicenter clinical trials, we developed a standardized version and tested its discriminative and evaluative properties...

Research Grants1

  1. Integrating and coordinating efforts in COPD guideline development
    Holger Schunemann; Fiscal Year: 2007
    ..End of Abstract) ..