Douglas L Schmucker

Summary

Affiliation: University of California
Country: USA

Publications

  1. ncbi Kefir milk enhances intestinal immunity in young but not old rats
    K Thoreux
    Cell Biology and Aging Section 151E, Department of Veterans Affairs Medical Center, San Francisco, CA 94121, USA
    J Nutr 131:807-12. 2001
  2. ncbi Aging impairs intestinal immunity
    D L Schmucker
    Cell Biology and Aging Section, 151E, Veterans Affairs Medical Center, 4150 Clement Street, San Francisco, CA 94121, USA
    Mech Ageing Dev 122:1397-411. 2001
  3. ncbi Liver function and phase I drug metabolism in the elderly: a paradox
    D L Schmucker
    Cell Biology and Aging Section 151E, Veterans Affairs Medical Center, San Francisco, California 94121, USA
    Drugs Aging 18:837-51. 2001
  4. ncbi Intestinal mucosal immunosenescence in rats
    Douglas L Schmucker
    Department of Anatomy, Veterans Affairs Medical Center, Cell Biology and Aging 151E, University of California, 4150 Clement Street, San Francisco, CA 94121, USA
    Exp Gerontol 37:197-203. 2002
  5. ncbi Expression of lymphocyte homing receptors alpha4beta7 and MAdCAM-l in young and old rats
    Douglas L Schmucker
    Cell Biology and Aging Section 151E, Veterans Affairs Medical Center, 4150 Clement Street, San Francisco, CA 94121, USA
    Exp Gerontol 37:1089-95. 2002
  6. ncbi Basis for the age-related decline in intestinal mucosal immunity
    Douglas L Schmucker
    Cell Biology and Aging Section, Veterans Affairs Medical Center, University of California, San Francisco, CA 94121, USA
    Clin Dev Immunol 10:167-72. 2003
  7. ncbi Age-related changes in liver structure and function: Implications for disease ?
    Douglas L Schmucker
    Cell Biology and Aging Section, Veterans Affairs Medical Center, and the Department of Anatomy, University of California, San Francisco, CA 94121, USA
    Exp Gerontol 40:650-9. 2005

Collaborators

Detail Information

Publications7

  1. ncbi Kefir milk enhances intestinal immunity in young but not old rats
    K Thoreux
    Cell Biology and Aging Section 151E, Department of Veterans Affairs Medical Center, San Francisco, CA 94121, USA
    J Nutr 131:807-12. 2001
    ..Most importantly, our data suggest that orally administered kefir enhances the specific intestinal mucosal immune response against CT in young adult, but not in senescent rats...
  2. ncbi Aging impairs intestinal immunity
    D L Schmucker
    Cell Biology and Aging Section, 151E, Veterans Affairs Medical Center, 4150 Clement Street, San Francisco, CA 94121, USA
    Mech Ageing Dev 122:1397-411. 2001
    ..Efforts to identify the mechanism(s) responsible for the age-related decline in intestinal mucosal immune responsiveness may benefit by focusing on the homing of IgA immunoblasts to the effector site...
  3. ncbi Liver function and phase I drug metabolism in the elderly: a paradox
    D L Schmucker
    Cell Biology and Aging Section 151E, Veterans Affairs Medical Center, San Francisco, California 94121, USA
    Drugs Aging 18:837-51. 2001
    ....
  4. ncbi Intestinal mucosal immunosenescence in rats
    Douglas L Schmucker
    Department of Anatomy, Veterans Affairs Medical Center, Cell Biology and Aging 151E, University of California, 4150 Clement Street, San Francisco, CA 94121, USA
    Exp Gerontol 37:197-203. 2002
    ..Binding assays did not detect age-associated declines in either the number or binding affinity of the polymeric immunoglobulin receptor expressed on rodent and monkey intestinal epithelial cells...
  5. ncbi Expression of lymphocyte homing receptors alpha4beta7 and MAdCAM-l in young and old rats
    Douglas L Schmucker
    Cell Biology and Aging Section 151E, Veterans Affairs Medical Center, 4150 Clement Street, San Francisco, CA 94121, USA
    Exp Gerontol 37:1089-95. 2002
    ..This is the first study to examine the expression of these two critical lymphocyte homing molecules as a function of age...
  6. ncbi Basis for the age-related decline in intestinal mucosal immunity
    Douglas L Schmucker
    Cell Biology and Aging Section, Veterans Affairs Medical Center, University of California, San Francisco, CA 94121, USA
    Clin Dev Immunol 10:167-72. 2003
    ..Intestinal mucosal immunosenescence is a consequence of reduced homing of IgA plasma cells to the intestinal LP as a result of declines in homing molecule expression...
  7. ncbi Age-related changes in liver structure and function: Implications for disease ?
    Douglas L Schmucker
    Cell Biology and Aging Section, Veterans Affairs Medical Center, and the Department of Anatomy, University of California, San Francisco, CA 94121, USA
    Exp Gerontol 40:650-9. 2005
    ....