Robert L Schmidt

Summary

Affiliation: University of Utah
Country: USA

Publications

  1. doi A mathematical procedure to estimate the impact of a change in method on discordance or misclassification at a decision limit in laboratory method comparison studies
    Robert L Schmidt
    Department of Pathology and ARUP Laboratories, University of Utah School of Medicine, Salt Lake City, UT, United States Electronic address
    Clin Chim Acta 440:23-30. 2015
  2. doi An analysis of clinical consultation activities in clinical pathology: who requests help and why
    Robert L Schmidt
    From the Department of Pathology, University of Utah School of Medicine and ARUP Laboratories, Salt Lake City, UT
    Am J Clin Pathol 142:286-91. 2014
  3. doi Quality appraisal of diagnostic accuracy studies in fine-needle aspiration cytology: a survey of risk of bias and comparability
    Robert L Schmidt
    Department of Pathology, University of Utah School of Medicine and ARUP Laboratories, Salt Lake City, Utah 84112, USA
    Arch Pathol Lab Med 137:566-75. 2013
  4. doi Understanding sources of bias in diagnostic accuracy studies
    Robert L Schmidt
    Department of Pathology, University of Utah School of Medicine and ARUP Laboratories, Salt Lake City, Utah 84112, USA
    Arch Pathol Lab Med 137:558-65. 2013
  5. doi Rapid on-site evaluation increases endoscopic ultrasound-guided fine-needle aspiration adequacy for pancreatic lesions
    Robert L Schmidt
    Department of Pathology, University of Utah School of Medicine, Salt Lake City, UT, USA
    Dig Dis Sci 58:872-82. 2013
  6. doi Risk-benefit analysis of sampling methods for fine-needle aspiration cytology: a mathematical modeling approach
    Robert L Schmidt
    Department of Pathology, University of Utah School of Medicine and ARUP Laboratories, Salt Lake City, UT 84112, USA
    Am J Clin Pathol 139:336-44. 2013
  7. doi Methods specification for diagnostic test accuracy studies in fine-needle aspiration cytology: a survey of reporting practice
    Robert L Schmidt
    Department of Pathology, University of Utah, Salt Lake City, UT 84112, USA
    Am J Clin Pathol 137:132-41. 2012
  8. doi The comparative effectiveness of fine-needle aspiration cytology sampling policies: a simulation study
    Robert L Schmidt
    Dept of Pathology, University of Utah School of Medicine, Salt Lake City, UT 84112, USA
    Am J Clin Pathol 138:823-30. 2012
  9. doi Diagnostic accuracy studies of fine-needle aspiration show wide variation in reporting of study population characteristics: implications for external validity
    Robert L Schmidt
    From the Department of Pathology, University of Utah School of Medicine and ARUP Laboratories, Salt Lake City, Utah
    Arch Pathol Lab Med 138:88-97. 2014
  10. doi Rapid on-site evaluation reduces needle passes in endoscopic ultrasound-guided fine-needle aspiration for solid pancreatic lesions: a risk-benefit analysis
    Robert L Schmidt
    Department of Pathology, University of Utah School of Medicine, Salt Lake City, UT, USA
    Dig Dis Sci 58:3280-6. 2013

Collaborators

Detail Information

Publications24

  1. doi A mathematical procedure to estimate the impact of a change in method on discordance or misclassification at a decision limit in laboratory method comparison studies
    Robert L Schmidt
    Department of Pathology and ARUP Laboratories, University of Utah School of Medicine, Salt Lake City, UT, United States Electronic address
    Clin Chim Acta 440:23-30. 2015
    ..Laboratories often adopt new methods. It would be useful to have a statistical procedure to estimate the incremental impact of a change in assay...
  2. doi An analysis of clinical consultation activities in clinical pathology: who requests help and why
    Robert L Schmidt
    From the Department of Pathology, University of Utah School of Medicine and ARUP Laboratories, Salt Lake City, UT
    Am J Clin Pathol 142:286-91. 2014
    ..To examine the distribution of callers who made consultation requests and to identify associations between caller categories and consultation topics...
  3. doi Quality appraisal of diagnostic accuracy studies in fine-needle aspiration cytology: a survey of risk of bias and comparability
    Robert L Schmidt
    Department of Pathology, University of Utah School of Medicine and ARUP Laboratories, Salt Lake City, Utah 84112, USA
    Arch Pathol Lab Med 137:566-75. 2013
    ..While diagnostic accuracy studies for fine-needle aspiration cytology (FNAC) are frequently published, the methodologic issues associated with this body of literature have never been reviewed...
  4. doi Understanding sources of bias in diagnostic accuracy studies
    Robert L Schmidt
    Department of Pathology, University of Utah School of Medicine and ARUP Laboratories, Salt Lake City, Utah 84112, USA
    Arch Pathol Lab Med 137:558-65. 2013
    ..Accuracy is an important feature of any diagnostic test. There has been an increasing awareness of deficiencies in study design that can create bias in estimates of test accuracy. Many pathologists are unaware of these sources of bias...
  5. doi Rapid on-site evaluation increases endoscopic ultrasound-guided fine-needle aspiration adequacy for pancreatic lesions
    Robert L Schmidt
    Department of Pathology, University of Utah School of Medicine, Salt Lake City, UT, USA
    Dig Dis Sci 58:872-82. 2013
    ....
  6. doi Risk-benefit analysis of sampling methods for fine-needle aspiration cytology: a mathematical modeling approach
    Robert L Schmidt
    Department of Pathology, University of Utah School of Medicine and ARUP Laboratories, Salt Lake City, UT 84112, USA
    Am J Clin Pathol 139:336-44. 2013
    ..Variable sampling policies using ROSE achieve greater per-case adequacy with fewer needle passes than sampling policies using a fixed number of passes if assessor accuracy is high...
  7. doi Methods specification for diagnostic test accuracy studies in fine-needle aspiration cytology: a survey of reporting practice
    Robert L Schmidt
    Department of Pathology, University of Utah, Salt Lake City, UT 84112, USA
    Am J Clin Pathol 137:132-41. 2012
    ..A more complete and standardized reporting of methods, perhaps by means of a checklist, would improve the interpretation of FNAC DTA studies...
  8. doi The comparative effectiveness of fine-needle aspiration cytology sampling policies: a simulation study
    Robert L Schmidt
    Dept of Pathology, University of Utah School of Medicine, Salt Lake City, UT 84112, USA
    Am J Clin Pathol 138:823-30. 2012
    ..Alternative ROSE assessors (eg, cytotechnologists) may be a cost-effective alternative to pathologists when the per-pass adequacy rate is moderate (60%-80%) or when the number of needle passes is limited...
  9. doi Diagnostic accuracy studies of fine-needle aspiration show wide variation in reporting of study population characteristics: implications for external validity
    Robert L Schmidt
    From the Department of Pathology, University of Utah School of Medicine and ARUP Laboratories, Salt Lake City, Utah
    Arch Pathol Lab Med 138:88-97. 2014
    ....
  10. doi Rapid on-site evaluation reduces needle passes in endoscopic ultrasound-guided fine-needle aspiration for solid pancreatic lesions: a risk-benefit analysis
    Robert L Schmidt
    Department of Pathology, University of Utah School of Medicine, Salt Lake City, UT, USA
    Dig Dis Sci 58:3280-6. 2013
    ..The trade-off between needle passes and adequacy has not been well-characterized...
  11. doi Needle size has only a limited effect on outcomes in EUS-guided fine needle aspiration: a systematic review and meta-analysis
    Kajsa E Affolter
    Department of Pathology, School of Medicine and ARUP Laboratories, University of Utah, Salt Lake City, UT, USA
    Dig Dis Sci 58:1026-34. 2013
    ..Several recent studies have investigated the utility of 19-, 22-, and 25-gauge needles in endoscopic ultrasound-guided fine needle aspiration (EUS-FNA) of pancreatic and peri-pancreatic tumors...
  12. doi A systematic review and meta-analysis of the diagnostic accuracy of frozen section for parotid gland lesions
    Robert L Schmidt
    Dept of Pathology, University of Utah, 15 North Medical Drive East, Salt Lake City, UT 84112, USA
    Am J Clin Pathol 136:729-38. 2011
    ..99 (95% confidence interval [CI], 0.98-1.00), 0.90 (95% CI, 0.81-0.94), and 0.99 (95% CI, 0.98-1.00), respectively. FS has acceptable accuracy (90% sensitivity, 99% specificity) and is consistently accurate across study centers...
  13. doi Ultrasound-guided core needle biopsy of salivary gland lesions: a systematic review and meta-analysis
    Benjamin L Witt
    Department of Pathology and ARUP Laboratories, University of Utah, Salt Lake City, Utah, U S A
    Laryngoscope 124:695-700. 2014
    ..To obtain summary estimates of the sensitivity and specificity of core needle biopsy for assessment of salivary gland lesions and to investigate sources of variation in accuracy between study locations...
  14. doi Significance of atypia in pancreatic and bile duct brushings: follow-up analysis of the categories atypical and suspicious for malignancy
    Barbara E Chadwick
    Department of Pathology, University of Utah School of Medicine and ARUP Laboratories, Salt Lake City, Utah
    Diagn Cytopathol 42:285-91. 2014
    ..The "atypical suspicious for malignancy" category has a follow-up similar to the "malignant" category while the "atypical favor reactive" category is associated with a clinical outcome similar to that of the "benign" category...
  15. doi Fine-needle aspiration cytology for the diagnosis of metastatic melanoma: systematic review and meta-analysis
    Brian J Hall
    Dept of Pathology, University of Utah School of Medicine, 15 N Medical Dr E, Salt Lake City, UT 84112
    Am J Clin Pathol 140:635-42. 2013
    ..To perform a thorough review and meta-analysis of studies that have shown non-image-guided fine-needle aspiration cytology (FNAC) to be highly sensitive and specific for assessing questionable metastatic melanoma to lymph nodes...
  16. doi A systematic review and meta-analysis of the diagnostic accuracy of ultrasound-guided core needle biopsy for salivary gland lesions
    Robert L Schmidt
    Department of Pathology, University of Utah, 15 N Medical Drive East, Salt Lake City, UT 84112, USA
    Am J Clin Pathol 136:516-26. 2011
    ..2%) inadequacy rate. CNB is more accurate than fine-needle aspiration, at least in some settings, but the best selection of which test to use for an individual patient and setting remains to be defined...
  17. doi Thrombin-mediated degradation of parathyroid hormone in serum tubes
    Sonia L La'ulu
    ARUP Institute for Clinical and Experimental Pathology, 500 Chipeta Way, Salt Lake City, UT 84108, USA
    Clin Chim Acta 437:191-6. 2014
    ....
  18. doi An analysis of clinical consultation activities in clinical chemistry: implications for transformation and resident training in chemical pathology
    Robert L Schmidt
    From the Department of Pathology, University of Utah School of Medicine and ARUP Laboratories, Salt Lake City Drs Schmidt, Garcia, and Hussong Path on Call, ARUP Laboratories, Salt Lake City, Utah Ms Panlener and the University of Utah School of Medicine and ARUP Laboratories, Salt Lake City Drs Ashwood and Jackson
    Arch Pathol Lab Med 138:671-7. 2014
    ..Although many have suggested that residency programs need to provide experience in clinical consultation, little has been written on the nature of consultation or on the methods of training...
  19. doi The influence of rapid onsite evaluation on the adequacy rate of fine-needle aspiration cytology: a systematic review and meta-analysis
    Robert L Schmidt
    Department of Pathology, University of Utah School of Medicine and ARUP Laboratories, Salt Lake City, UT 84112, USA
    Am J Clin Pathol 139:300-8. 2013
    ..Studies with high non-ROSE adequacy rates showed low improvement after ROSE was implemented. Studies must account for the effect of the non-ROSE adequacy rate to determine the effect of ROSE on FNA adequacy rates...
  20. doi Verification bias in diagnostic accuracy studies for fine- and core needle biopsy of salivary gland lesions in otolaryngology journals: a systematic review and analysis
    Robert L Schmidt
    Department of Pathology and ARUP Laboratories, University of Utah School of Medicine, Salt Lake City, Utah
    Head Neck 36:1654-61. 2014
    ..Diagnostic test accuracy (DTA) studies for needle biopsy are frequently published in otolaryngology journals, but this body of literature has not been assessed for verification bias...
  21. doi Gastrointestinal stromal tumors: clinical significance of p53 expression, MDM2 amplification, and KIT mutation status
    Michelle L Wallander
    ARUP Institute for Clinical and Experimental Pathology, University of Utah School of Medicine, Salt Lake City, UT 84112, USA
    Appl Immunohistochem Mol Morphol 21:308-12. 2013
    ..We investigated the prognostic value of p53 protein expression and MDM2 gene amplification in a series of GISTs...
  22. doi Rapid onsite evaluation improves the adequacy of fine-needle aspiration for thyroid lesions: a systematic review and meta-analysis
    Benjamin L Witt
    Department of Anatomic Pathology, University of Utah School of Medicine ARUP Laboratories, Salt Lake City, Utah 84112, USA
    Thyroid 23:428-35. 2013
    ..To our knowledge, no meta-analysis of the literature on this subject has been undertaken...
  23. doi HER2/neu gene amplification heterogeneity: the significance of cells with a 3:1 HER2/CEP17 ratio
    Lester J Layfield
    Department of Pathology, University of Utah, USA
    Appl Immunohistochem Mol Morphol 20:543-9. 2012
    ..Moreover, 3:1 HER2/CEP17 ratio cells are a poor predictor for the presence of additional amplified cells in a sample...
  24. doi A systematic review and meta-analysis of the diagnostic accuracy of fine-needle aspiration cytology for parotid gland lesions
    Robert L Schmidt
    Department of Pathology, University of Utah School of Medicine, Salt Lake City, UT 84112, USA
    Am J Clin Pathol 136:45-59. 2011
    ..There is a need to improve the quality of reporting and to improve study designs to remove or assess the impact of bias...