KRISTINA HILDEGARD SCHMIDT

Summary

Affiliation: University of South Florida
Country: USA

Publications

  1. pmc Control of translocations between highly diverged genes by Sgs1, the Saccharomyces cerevisiae homolog of the Bloom's syndrome protein
    Kristina H Schmidt
    Department of Biology, University of South Florida, 4202 E Fowler Avenue, SCA110, Tampa, FL 33620, USA
    Mol Cell Biol 26:5406-20. 2006
  2. pmc Suppression of spontaneous genome rearrangements in yeast DNA helicase mutants
    Kristina H Schmidt
    Ludwig Institute for Cancer Research, University of California at San Diego, La Jolla, CA 92093, USA
    Proc Natl Acad Sci U S A 103:18196-201. 2006
  3. pmc Defects in DNA lesion bypass lead to spontaneous chromosomal rearrangements and increased cell death
    Kristina H Schmidt
    Department of Cell Biology, Microbiology and Molecular Biology, University of South Florida, Tampa, FL 33620, USA
    Eukaryot Cell 9:315-24. 2010
  4. pmc Requirement of Rrm3 helicase for repair of spontaneous DNA lesions in cells lacking Srs2 or Sgs1 helicase
    Kristina H Schmidt
    Ludwig Institute for Cancer Research, University of California San Diego School of Medicine, La Jolla, California 92093, USA
    Mol Cell Biol 24:3213-26. 2004
  5. pmc Dynamic changes in protein-protein interaction and protein phosphorylation probed with amine-reactive isotope tag
    Marcus B Smolka
    Ludwig Institute for Cancer Research, Department of Cellular and Molecular Medicine, University of California San Diego, La Jolla, California 92093, USA
    Mol Cell Proteomics 4:1358-69. 2005
  6. ncbi request reprint Saccharomyces cerevisiae RRM3, a 5' to 3' DNA helicase, physically interacts with proliferating cell nuclear antigen
    Kristina H Schmidt
    Ludwig Institute for Cancer Research, Cancer Center, and Department of Medicine, University of California San Diego School of Medicine, La Jolla, California 92093 0660, USA
    J Biol Chem 277:45331-7. 2002
  7. pmc Formation of complex and unstable chromosomal translocations in yeast
    Kristina H Schmidt
    Department of Cell Biology, Microbiology and Molecular Biology, University of South Florida, Tampa, Florida, United States of America
    PLoS ONE 5:e12007. 2010
  8. ncbi request reprint Analysis of gross-chromosomal rearrangements in Saccharomyces cerevisiae
    Kristina H Schmidt
    Ludwig Institute for Cancer Research, University of North Texas, Health Science Center, Fort Worth, USA
    Methods Enzymol 409:462-76. 2006
  9. pmc The C-terminal domain of yeast PCNA is required for physical and functional interactions with Cdc9 DNA ligase
    Sangeetha Vijayakumar
    Radiation Oncology Research Laboratory, Department of Radiation Oncology and The Marlene and Stewart Greenebaum Cancer Center, University of Maryland School of Medicine, Baltimore, MD 21201 1509, USA
    Nucleic Acids Res 35:1624-37. 2007

Research Grants

  1. Suppression of translocations by RecQ-like DNA helicases
    KRISTINA HILDEGARD SCHMIDT; Fiscal Year: 2010
  2. Suppression of translocations by RecQ-like DNA helicases
    KRISTINA HILDEGARD SCHMIDT; Fiscal Year: 2010

Collaborators

Detail Information

Publications9

  1. pmc Control of translocations between highly diverged genes by Sgs1, the Saccharomyces cerevisiae homolog of the Bloom's syndrome protein
    Kristina H Schmidt
    Department of Biology, University of South Florida, 4202 E Fowler Avenue, SCA110, Tampa, FL 33620, USA
    Mol Cell Biol 26:5406-20. 2006
    ..The translocation structures observed suggest involvement of a dicentric intermediate and break-induced replication with multiple cycles of DNA template switching...
  2. pmc Suppression of spontaneous genome rearrangements in yeast DNA helicase mutants
    Kristina H Schmidt
    Ludwig Institute for Cancer Research, University of California at San Diego, La Jolla, CA 92093, USA
    Proc Natl Acad Sci U S A 103:18196-201. 2006
    ..These findings demonstrate that different nonreplicative helicases function at the interface between replication and repair to maintain genome integrity...
  3. pmc Defects in DNA lesion bypass lead to spontaneous chromosomal rearrangements and increased cell death
    Kristina H Schmidt
    Department of Cell Biology, Microbiology and Molecular Biology, University of South Florida, Tampa, FL 33620, USA
    Eukaryot Cell 9:315-24. 2010
    ....
  4. pmc Requirement of Rrm3 helicase for repair of spontaneous DNA lesions in cells lacking Srs2 or Sgs1 helicase
    Kristina H Schmidt
    Ludwig Institute for Cancer Research, University of California San Diego School of Medicine, La Jolla, California 92093, USA
    Mol Cell Biol 24:3213-26. 2004
    ..These observations identify Rrm3 as a new member of a network of pathways, involving Sgs1 and Srs2 helicases and Mus81 endonuclease, suggested to act during repair of stalled replication forks...
  5. pmc Dynamic changes in protein-protein interaction and protein phosphorylation probed with amine-reactive isotope tag
    Marcus B Smolka
    Ludwig Institute for Cancer Research, Department of Cellular and Molecular Medicine, University of California San Diego, La Jolla, California 92093, USA
    Mol Cell Proteomics 4:1358-69. 2005
    ....
  6. ncbi request reprint Saccharomyces cerevisiae RRM3, a 5' to 3' DNA helicase, physically interacts with proliferating cell nuclear antigen
    Kristina H Schmidt
    Ludwig Institute for Cancer Research, Cancer Center, and Department of Medicine, University of California San Diego School of Medicine, La Jolla, California 92093 0660, USA
    J Biol Chem 277:45331-7. 2002
    ..The results presented here suggest that the RRM3 helicase functions at the replication fork...
  7. pmc Formation of complex and unstable chromosomal translocations in yeast
    Kristina H Schmidt
    Department of Cell Biology, Microbiology and Molecular Biology, University of South Florida, Tampa, Florida, United States of America
    PLoS ONE 5:e12007. 2010
    ..These findings provide insight into eukaryotic genome instability, especially the formation of translocations and the sources of intraclonal heterogeneity, both of which are often associated with human cancers...
  8. ncbi request reprint Analysis of gross-chromosomal rearrangements in Saccharomyces cerevisiae
    Kristina H Schmidt
    Ludwig Institute for Cancer Research, University of North Texas, Health Science Center, Fort Worth, USA
    Methods Enzymol 409:462-76. 2006
    ..This GCR analysis provides an effective tool for the assessment of the contribution by multiple cellular mechanisms to the maintenance of genome integrity...
  9. pmc The C-terminal domain of yeast PCNA is required for physical and functional interactions with Cdc9 DNA ligase
    Sangeetha Vijayakumar
    Radiation Oncology Research Laboratory, Department of Radiation Oncology and The Marlene and Stewart Greenebaum Cancer Center, University of Maryland School of Medicine, Baltimore, MD 21201 1509, USA
    Nucleic Acids Res 35:1624-37. 2007
    ....

Research Grants4

  1. Suppression of translocations by RecQ-like DNA helicases
    KRISTINA HILDEGARD SCHMIDT; Fiscal Year: 2010
    ....
  2. Suppression of translocations by RecQ-like DNA helicases
    KRISTINA HILDEGARD SCHMIDT; Fiscal Year: 2010
    ....